Project name: 3giz:L
Status: done
submitted: 2019-03-20 20:09:22, status changed: 2019-03-20 20:17:04
Settings
|
Chain sequence(s)
|
L: EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6761
-
Maximal score value
-
1.5489
-
Average score
-
-0.817
-
Total score value
-
-172.3949
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
L |
-1.1019 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
V |
L |
1.0640 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.5914 |
|
| 6 |
Q |
L |
-0.6325 |
|
| 7 |
S |
L |
-0.7753 |
|
| 8 |
P |
L |
-0.3081 |
|
| 9 |
A |
L |
-0.3665 |
|
| 10 |
T |
L |
-0.1673 |
|
| 11 |
L |
L |
-0.0418 |
|
| 12 |
S |
L |
-0.4237 |
|
| 13 |
L |
L |
-0.9204 |
|
| 14 |
S |
L |
-1.3413 |
|
| 15 |
P |
L |
-1.6146 |
|
| 16 |
G |
L |
-1.6532 |
|
| 17 |
E |
L |
-2.1649 |
|
| 18 |
R |
L |
-2.5781 |
|
| 19 |
A |
L |
0.0000 |
|
| 20 |
T |
L |
-0.5790 |
|
| 21 |
L |
L |
0.0000 |
|
| 22 |
S |
L |
-0.9887 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.2725 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.9140 |
|
| 27 |
Q |
L |
-1.4524 |
|
| 28 |
S |
L |
-1.2127 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
S |
L |
-0.7496 |
|
| 31 |
S |
L |
-0.4459 |
|
| 32 |
Y |
L |
-0.3049 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.3668 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.0042 |
|
| 39 |
K |
L |
-1.7447 |
|
| 40 |
P |
L |
-1.4321 |
|
| 41 |
G |
L |
-1.3761 |
|
| 42 |
Q |
L |
-1.9005 |
|
| 43 |
A |
L |
-1.0594 |
|
| 44 |
P |
L |
-0.8855 |
|
| 45 |
R |
L |
-0.8108 |
|
| 46 |
L |
L |
0.1792 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.6219 |
|
| 50 |
D |
L |
-1.3396 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-1.3793 |
|
| 53 |
N |
L |
-2.0774 |
|
| 54 |
R |
L |
-1.7929 |
|
| 55 |
A |
L |
-0.9416 |
|
| 56 |
T |
L |
-0.6396 |
|
| 57 |
G |
L |
-0.6906 |
|
| 58 |
I |
L |
0.0000 |
|
| 59 |
P |
L |
-0.4643 |
|
| 60 |
A |
L |
-0.4131 |
|
| 61 |
R |
L |
-0.7163 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.8315 |
|
| 64 |
G |
L |
-0.8899 |
|
| 65 |
S |
L |
-1.0627 |
|
| 66 |
G |
L |
-1.3705 |
|
| 67 |
S |
L |
-1.0040 |
|
| 68 |
G |
L |
-1.1583 |
|
| 69 |
T |
L |
-1.9133 |
|
| 70 |
D |
L |
-2.7466 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.9255 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6410 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3832 |
|
| 77 |
S |
L |
-1.6458 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
E |
L |
-1.8729 |
|
| 80 |
P |
L |
-1.4030 |
|
| 81 |
E |
L |
-1.9788 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-0.5419 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
V |
L |
-0.1145 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.2045 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
R |
L |
-0.9277 |
|
| 92 |
S |
L |
-0.5100 |
|
| 93 |
N |
L |
-0.5248 |
|
| 94 |
W |
L |
0.6370 |
|
| 95 |
P |
L |
0.6509 |
|
| 96 |
I |
L |
1.5489 |
|
| 97 |
T |
L |
1.0570 |
|
| 98 |
F |
L |
1.3575 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-0.7570 |
|
| 101 |
G |
L |
-0.4742 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
R |
L |
-0.4552 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
0.0000 |
|
| 106 |
I |
L |
-0.7088 |
|
| 107 |
K |
L |
-1.3017 |
|
| 108 |
R |
L |
-0.9378 |
|
| 109 |
T |
L |
-0.1860 |
|
| 110 |
V |
L |
0.0593 |
|
| 111 |
A |
L |
-0.0792 |
|
| 112 |
A |
L |
-0.2920 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1581 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.3329 |
|
| 117 |
I |
L |
1.2789 |
|
| 118 |
F |
L |
1.5312 |
|
| 119 |
P |
L |
-0.1984 |
|
| 120 |
P |
L |
-0.8053 |
|
| 121 |
S |
L |
-1.7494 |
|
| 122 |
D |
L |
-3.1835 |
|
| 123 |
E |
L |
-3.3325 |
|
| 124 |
Q |
L |
-2.3896 |
|
| 125 |
L |
L |
-2.3765 |
|
| 126 |
K |
L |
-2.8864 |
|
| 127 |
S |
L |
-1.8121 |
|
| 128 |
G |
L |
-1.4203 |
|
| 129 |
T |
L |
-0.9308 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0600 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7400 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5549 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6545 |
|
| 138 |
N |
L |
-1.2194 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.7806 |
|
| 142 |
R |
L |
-2.8634 |
|
| 143 |
E |
L |
-3.1182 |
|
| 144 |
A |
L |
-2.3092 |
|
| 145 |
K |
L |
-2.4254 |
|
| 146 |
V |
L |
-1.2579 |
|
| 147 |
Q |
L |
-0.6663 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.6753 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-2.1526 |
|
| 152 |
N |
L |
-1.6657 |
|
| 153 |
A |
L |
-0.3725 |
|
| 154 |
L |
L |
0.4611 |
|
| 155 |
Q |
L |
-0.4570 |
|
| 156 |
S |
L |
-0.7441 |
|
| 157 |
G |
L |
-1.4205 |
|
| 158 |
N |
L |
-1.7948 |
|
| 159 |
S |
L |
-1.8551 |
|
| 160 |
Q |
L |
-2.4775 |
|
| 161 |
E |
L |
-2.3565 |
|
| 162 |
S |
L |
-1.1750 |
|
| 163 |
V |
L |
-0.7481 |
|
| 164 |
T |
L |
-1.1152 |
|
| 165 |
E |
L |
-1.9991 |
|
| 166 |
Q |
L |
-1.7698 |
|
| 167 |
D |
L |
-2.0854 |
|
| 168 |
S |
L |
-1.9831 |
|
| 169 |
K |
L |
-2.2502 |
|
| 170 |
D |
L |
-1.6328 |
|
| 171 |
S |
L |
-1.6384 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9599 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.5141 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.7596 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.7371 |
|
| 181 |
L |
L |
-0.8438 |
|
| 182 |
S |
L |
-1.0585 |
|
| 183 |
K |
L |
-2.0148 |
|
| 184 |
A |
L |
-1.8386 |
|
| 185 |
D |
L |
-2.7106 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.4069 |
|
| 188 |
K |
L |
-3.6761 |
|
| 189 |
H |
L |
-3.4834 |
|
| 190 |
K |
L |
-3.6099 |
|
| 191 |
V |
L |
-2.3634 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.7165 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2325 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7713 |
|
| 200 |
G |
L |
-0.4976 |
|
| 201 |
L |
L |
-0.2848 |
|
| 202 |
S |
L |
-0.4702 |
|
| 203 |
S |
L |
-0.4353 |
|
| 204 |
P |
L |
-0.5506 |
|
| 205 |
V |
L |
-0.0493 |
|
| 206 |
T |
L |
-0.3525 |
|
| 207 |
K |
L |
-0.2490 |
|
| 208 |
S |
L |
-0.5328 |
|
| 209 |
F |
L |
-1.0230 |
|
| 210 |
N |
L |
-2.6153 |
|
| 211 |
R |
L |
-3.2867 |
|