Project name: wtrbd

Chain sequence(s)	C: TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGP
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.1283
• Maximal score value: 1.7421
• Average score: -0.1947
• Total score value: -37.9573

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
333	T	C	-0.3023
334	N	C	-0.9855
335	L	C	1.3282
336	C	C	0.3524
337	P	C	-0.0281
338	F	C	0.1121
339	G	C	-0.6434
340	E	C	-1.8831
341	V	C	0.0000
342	F	C	0.0000
343	N	C	-1.2701
344	A	C	-0.2307
345	T	C	-0.4052
346	R	C	-1.8570
347	F	C	0.0000
348	A	C	0.0051
349	S	C	-0.0231
350	V	C	0.0000
351	Y	C	0.1562
352	A	C	0.0371
353	W	C	0.0000
354	N	C	-1.4326
355	R	C	-1.2536
356	K	C	-1.3322
357	R	C	-1.9844
358	I	C	0.0000
359	S	C	-0.3239
360	N	C	-1.2896
361	C	C	0.0000
362	V	C	0.7123
363	A	C	0.0000
364	D	C	-1.2793
365	Y	C	-0.1372
366	S	C	0.1805
367	V	C	1.7421
368	L	C	0.0000
369	Y	C	1.0797
370	N	C	-1.0449
371	S	C	-0.3060
372	A	C	0.0042
373	S	C	-0.1487
374	F	C	0.2305
375	S	C	-0.1492
376	T	C	0.0634
377	F	C	0.4128
378	K	C	-1.1660
379	C	C	0.0133
380	Y	C	0.4443
381	G	C	-0.2423
382	V	C	0.2070
383	S	C	-0.0665
384	P	C	-0.0743
385	T	C	-0.3887
386	K	C	-1.7129
387	L	C	0.0000
388	N	C	-0.7892
389	D	C	-1.7294
390	L	C	0.4870
391	C	C	0.3991
392	F	C	0.2282
393	T	C	0.0000
394	N	C	-0.1749
395	V	C	0.0000
396	Y	C	-0.0700
397	A	C	0.0000
398	D	C	0.0000
399	S	C	0.0000
400	F	C	0.0000
401	V	C	0.0000
402	I	C	0.0000
403	R	C	-0.3122
404	G	C	-0.3050
405	D	C	-0.8181
406	E	C	0.0000
407	V	C	-0.1253
408	R	C	-1.8292
409	Q	C	-0.4690
410	I	C	0.0000
411	A	C	-0.0028
412	P	C	-0.3348
413	G	C	-0.5568
414	Q	C	-0.5396
415	T	C	-0.1690
416	G	C	-0.3493
417	K	C	-1.3272
418	I	C	0.0000
419	A	C	0.0000
420	D	C	-0.3345
421	Y	C	0.1969
422	N	C	0.0000
423	Y	C	0.0000
424	K	C	-0.5409
425	L	C	0.0000
426	P	C	-0.3691
427	D	C	-2.1283
428	D	C	-2.1159
429	F	C	0.0000
430	T	C	-0.1052
431	G	C	0.0000
432	C	C	0.0000
433	V	C	0.0000
434	I	C	0.0000
435	A	C	0.0000
436	W	C	0.0569
437	N	C	-0.4053
438	S	C	0.0000
439	N	C	-0.4746
440	N	C	-1.0358
441	L	C	1.3163
442	D	C	0.0000
443	S	C	-0.3506
444	K	C	-1.3996
445	V	C	1.3726
446	G	C	-0.1479
447	G	C	-0.4169
448	N	C	-0.1014
449	Y	C	1.0594
450	N	C	-1.0329
451	Y	C	0.0000
452	L	C	0.3915
453	Y	C	0.2202
454	R	C	0.0000
455	L	C	0.3147
456	F	C	0.4373
457	R	C	-0.6105
458	K	C	-1.8094
459	S	C	-0.7586
460	N	C	-1.3386
461	L	C	0.0000
462	K	C	-1.7193
463	P	C	-0.3659
464	F	C	0.4958
465	E	C	-0.5800
466	R	C	-1.4506
467	D	C	0.0000
468	I	C	1.2111
469	S	C	0.0912
470	T	C	-0.4257
471	E	C	-1.7778
472	I	C	0.0134
473	Y	C	0.2010
474	Q	C	-0.6953
475	A	C	-0.2484
476	G	C	-0.3253
477	S	C	-0.2578
478	T	C	-0.1565
479	P	C	-0.2530
480	C	C	-0.2006
481	N	C	-1.3449
482	G	C	-0.3794
483	V	C	1.3506
484	E	C	-1.5563
485	G	C	-0.3754
486	F	C	1.6667
487	N	C	-0.7417
488	C	C	-0.3005
489	Y	C	0.7586
490	F	C	1.2987
491	P	C	0.0000
492	L	C	0.0406
493	Q	C	-0.6327
494	S	C	-0.1293
495	Y	C	0.0000
496	G	C	-0.0631
497	F	C	0.0000
498	Q	C	-0.4836
499	P	C	-0.2447
500	T	C	-0.1464
501	N	C	-0.3626
502	G	C	-0.1854
503	V	C	1.6624
504	G	C	0.2800
505	Y	C	0.4556
506	Q	C	-0.0453
507	P	C	0.0000
508	Y	C	0.0850
509	R	C	0.0000
510	V	C	0.0000
511	V	C	0.0000
512	V	C	0.0000
513	L	C	0.0000
514	S	C	-0.0208
515	F	C	0.0000
516	E	C	-0.4487
517	L	C	1.6989
518	L	C	1.6525
519	H	C	-0.7003
520	A	C	-0.2036
521	P	C	-0.2452
522	A	C	-0.0022
523	T	C	-0.0153
524	V	C	0.0000
525	C	C	0.3413
526	G	C	-0.1324
527	P	C	-0.2674