Project name: mAb1

Chain sequence(s)	H: QVQLQQWGAGLLKPSETLSLTCAVSGGSFSGYHWSWIRQPPGKGLEWIGEINQSGNTNYNPSLKSRVTISEDTSKNQFSLKLSSVTAADTAVYFCARGGFCSGGNCYYYGMDVWGQGTTVTVSS; L: YELTQPPSVSVSPGLTARITCSGDALPKKYAYWYQQKSGQAPVLVIYEDSKRPSGIPERFSGSSSGTMATLTVTGAQVEDEADYYCYSSDTGGDHRVFGGGTKLTVLGQP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.5434
• Maximal score value: 2.0289
• Average score: -0.6233
• Total score value: -145.862

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
3	Y	L	-0.1774
4	E	L	-1.6080
5	L	L	0.0000
6	T	L	-0.7231
7	Q	L	-0.4319
8	P	L	-0.6320
9	P	L	-0.9529
10	S	L	-0.8589
11	V	L	-0.3452
12	S	L	-0.1002
13	V	L	0.0000
14	S	L	0.4045
15	P	L	0.0853
16	G	L	0.1264
17	L	L	1.1415
18	T	L	-0.0620
19	A	L	-0.6327
20	R	L	-1.8529
21	I	L	0.0000
22	T	L	-0.5532
23	C	L	0.0000
24	S	L	-0.8359
25	G	L	-1.2989
26	D	L	-2.3743
27	A	L	0.0000
28	L	L	0.0000
29	P	L	-1.7681
30	K	L	-2.2060
31	K	L	-1.2279
32	Y	L	-0.4272
33	A	L	0.0000
34	Y	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	-0.3438
38	Q	L	0.0000
39	K	L	-1.5440
40	S	L	-1.1654
41	G	L	-1.4100
42	Q	L	-1.7777
43	A	L	-0.8194
44	P	L	0.0000
45	V	L	0.7799
46	L	L	0.0000
47	V	L	0.0000
48	I	L	0.0000
49	Y	L	-1.0827
50	E	L	-1.3155
51	D	L	-2.5434
52	S	L	-1.9812
53	K	L	-2.3642
54	R	L	-2.2394
55	P	L	-1.1666
56	S	L	-0.9489
57	G	L	-0.8738
58	I	L	-0.7410
59	P	L	-1.2701
60	E	L	-2.2398
61	R	L	-1.3616
62	F	L	0.0000
63	S	L	-1.5107
64	G	L	-1.2176
65	S	L	-1.0114
66	S	L	-0.6425
67	S	L	-0.4466
68	G	L	-1.0619
69	T	L	-1.0995
70	M	L	-0.3187
71	A	L	0.0000
72	T	L	0.0000
73	L	L	0.0000
74	T	L	-0.9993
75	V	L	0.0000
76	T	L	-0.6392
77	G	L	-0.1798
78	A	L	0.0000
79	Q	L	-0.8755
80	V	L	-0.1047
81	E	L	-1.6156
82	D	L	0.0000
83	E	L	-1.3035
84	A	L	0.0000
85	D	L	-1.4616
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	Y	L	0.0000
90	S	L	0.0000
91	S	L	0.0000
92	D	L	-1.4109
93	T	L	-1.4779
94	G	L	-0.9831
95	G	L	-1.3140
95A	D	L	-2.2971
95B	H	L	-1.3696
96	R	L	0.0000
97	V	L	-0.4049
98	F	L	-0.3571
99	G	L	0.0000
100	G	L	-1.3465
101	G	L	-1.1882
102	T	L	0.0000
103	K	L	-2.1186
104	L	L	0.0000
105	T	L	-0.2237
106	V	L	0.0000
107	L	L	0.6120
108	G	L	-0.3905
109	Q	L	-0.6370
110	P	L	-0.6170
1	Q	H	-1.6439
2	V	H	-1.3319
3	Q	H	-2.0454
4	L	H	0.0000
5	Q	H	-1.5361
6	Q	H	0.0000
7	W	H	0.7795
8	G	H	0.6033
9	A	H	0.6826
10	G	H	0.8499
11	L	H	1.1870
12	L	H	-0.2339
13	K	H	-1.6104
14	P	H	-1.2652
15	S	H	-1.3784
16	E	H	-1.9988
17	T	H	-1.4903
18	L	H	0.0000
19	S	H	-0.7340
20	L	H	0.0000
21	T	H	-0.2505
22	C	H	0.0000
23	A	H	-1.1167
24	V	H	0.0000
25	S	H	-1.3758
26	G	H	-1.3497
27	G	H	-1.1495
28	S	H	-0.6384
29	F	H	0.0000
30	S	H	-0.8109
31	G	H	-0.5249
32	Y	H	-0.1177
33	H	H	-0.6151
34	W	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	I	H	0.0000
38	R	H	0.0000
39	Q	H	-0.7522
40	P	H	-0.9098
41	P	H	-1.0339
42	G	H	-1.4766
43	K	H	-2.2527
44	G	H	-1.3788
45	L	H	0.0000
46	E	H	-0.7227
47	W	H	0.0000
48	I	H	0.0000
49	G	H	0.0000
50	E	H	-0.9443
51	I	H	0.0000
52	N	H	-1.7106
53	Q	H	-1.7190
54	S	H	-1.3391
55	G	H	-1.5435
56	N	H	-2.0935
57	T	H	-1.6330
58	N	H	-2.2349
59	Y	H	-1.5011
60	N	H	0.0000
61	P	H	-1.3182
62	S	H	-0.8338
63	L	H	0.0000
64	K	H	-2.1900
65	S	H	-1.3292
66	R	H	-1.4398
67	V	H	0.0000
68	T	H	-1.2085
69	I	H	0.0000
70	S	H	-1.2435
71	E	H	-1.7048
72	D	H	-1.8430
73	T	H	-1.6326
74	S	H	-1.4995
75	K	H	-2.3849
76	N	H	-1.9503
77	Q	H	-1.7762
78	F	H	0.0000
79	S	H	-0.6387
80	L	H	0.0000
81	K	H	-1.7780
82	L	H	0.0000
82A	S	H	-1.2315
82B	S	H	-1.1186
82C	V	H	0.0000
83	T	H	-0.5998
84	A	H	-0.2068
85	A	H	0.0448
86	D	H	0.0000
87	T	H	0.1868
88	A	H	0.0000
89	V	H	0.0617
90	Y	H	0.0000
91	F	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	R	H	-0.4342
95	G	H	0.0000
96	G	H	0.6114
97	F	H	2.0289
98	C	H	1.4093
99	S	H	0.3380
100	G	H	-0.7306
100A	G	H	-1.1512
100B	N	H	-1.4487
100C	C	H	-0.3851
100D	Y	H	1.1825
100E	Y	H	0.0000
100F	Y	H	1.1544
100G	G	H	0.0000
100H	M	H	0.0000
101	D	H	-0.4512
102	V	H	-0.4720
103	W	H	-0.6348
104	G	H	0.0000
105	Q	H	-1.8769
106	G	H	-0.8753
107	T	H	-0.1419
108	T	H	0.3544
109	V	H	0.0000
110	T	H	0.3336
111	V	H	0.0000
112	S	H	-0.4121
113	S	H	-0.5334