Project name: 3qwo:L
Status: done
submitted: 2019-03-20 20:13:13, status changed: 2019-03-20 20:25:40
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSTLSASVGDRVTITCSASSRVGYMHWYQQKPGKAPKLLIYDTSKLASGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCFQGSGYPFTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.1761
-
Maximal score value
-
1.7917
-
Average score
-
-0.7564
-
Total score value
-
-158.8391
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.5969 |
|
| 2 |
I |
L |
-1.0360 |
|
| 3 |
Q |
L |
-1.1783 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.4972 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.5315 |
|
| 8 |
P |
L |
-0.5334 |
|
| 9 |
S |
L |
-0.6588 |
|
| 10 |
T |
L |
-0.6270 |
|
| 11 |
L |
L |
-0.5577 |
|
| 12 |
S |
L |
-0.8084 |
|
| 13 |
A |
L |
-1.0131 |
|
| 14 |
S |
L |
-0.9347 |
|
| 15 |
V |
L |
-0.3437 |
|
| 16 |
G |
L |
-0.8964 |
|
| 17 |
D |
L |
-1.8684 |
|
| 18 |
R |
L |
-2.3653 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6122 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.5629 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
S |
L |
-1.2965 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-1.4815 |
|
| 27 |
S |
L |
-1.7780 |
|
| 29 |
R |
L |
-2.2538 |
|
| 30 |
V |
L |
0.0000 |
|
| 31 |
G |
L |
-0.6205 |
|
| 32 |
Y |
L |
0.2670 |
|
| 33 |
M |
L |
0.0000 |
|
| 34 |
H |
L |
0.2547 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.3558 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.2255 |
|
| 39 |
K |
L |
-1.8099 |
|
| 40 |
P |
L |
-1.5867 |
|
| 41 |
G |
L |
-1.6712 |
|
| 42 |
K |
L |
-2.2858 |
|
| 43 |
A |
L |
-1.2778 |
|
| 44 |
P |
L |
-1.0629 |
|
| 45 |
K |
L |
-1.0697 |
|
| 46 |
L |
L |
0.2492 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.2054 |
|
| 50 |
D |
L |
-0.7524 |
|
| 51 |
T |
L |
0.0000 |
|
| 52 |
S |
L |
-1.0348 |
|
| 53 |
K |
L |
-1.6850 |
|
| 54 |
L |
L |
-0.4136 |
|
| 55 |
A |
L |
0.0000 |
|
| 56 |
S |
L |
-0.4452 |
|
| 57 |
G |
L |
-0.3680 |
|
| 58 |
V |
L |
-0.3273 |
|
| 59 |
P |
L |
-0.3084 |
|
| 60 |
S |
L |
-0.3928 |
|
| 61 |
R |
L |
-0.7627 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.5509 |
|
| 64 |
G |
L |
0.0000 |
|
| 65 |
S |
L |
-0.8557 |
|
| 66 |
G |
L |
-0.9101 |
|
| 67 |
S |
L |
-1.1084 |
|
| 68 |
G |
L |
-1.4924 |
|
| 69 |
T |
L |
-1.6961 |
|
| 70 |
E |
L |
-2.1577 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.6442 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6061 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3436 |
|
| 77 |
S |
L |
-1.1862 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.4852 |
|
| 80 |
P |
L |
-2.0192 |
|
| 81 |
D |
L |
-2.4503 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-0.6380 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.4521 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
F |
L |
1.1693 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
G |
L |
0.7527 |
|
| 92 |
S |
L |
0.0971 |
|
| 93 |
G |
L |
0.3220 |
|
| 94 |
Y |
L |
1.1965 |
|
| 95 |
P |
L |
0.8092 |
|
| 96 |
F |
L |
1.5797 |
|
| 97 |
T |
L |
1.0954 |
|
| 98 |
F |
L |
1.7917 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
G |
L |
-0.2868 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.1729 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.1799 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.2751 |
|
| 108 |
R |
L |
-0.7494 |
|
| 109 |
T |
L |
-0.0723 |
|
| 110 |
V |
L |
0.2540 |
|
| 111 |
A |
L |
0.0044 |
|
| 112 |
A |
L |
-0.2361 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.0479 |
|
| 115 |
V |
L |
0.4363 |
|
| 116 |
F |
L |
1.4293 |
|
| 117 |
I |
L |
1.4960 |
|
| 118 |
F |
L |
1.7186 |
|
| 119 |
P |
L |
-0.0309 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.7945 |
|
| 122 |
D |
L |
-3.2842 |
|
| 123 |
E |
L |
-3.4400 |
|
| 124 |
Q |
L |
-2.5802 |
|
| 125 |
L |
L |
-2.6040 |
|
| 126 |
K |
L |
-3.0126 |
|
| 127 |
S |
L |
-1.9115 |
|
| 128 |
G |
L |
-1.6236 |
|
| 129 |
T |
L |
-1.5361 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0261 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.8433 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.6411 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5566 |
|
| 138 |
N |
L |
-1.3241 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.7825 |
|
| 142 |
R |
L |
-2.9968 |
|
| 143 |
E |
L |
-3.2576 |
|
| 144 |
A |
L |
-2.3632 |
|
| 145 |
K |
L |
-2.2700 |
|
| 146 |
V |
L |
-1.1107 |
|
| 147 |
Q |
L |
-0.5865 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.3695 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.7786 |
|
| 152 |
N |
L |
-1.3975 |
|
| 153 |
A |
L |
-0.1626 |
|
| 154 |
L |
L |
0.7781 |
|
| 155 |
Q |
L |
-0.0559 |
|
| 156 |
S |
L |
-0.5256 |
|
| 157 |
G |
L |
-0.9972 |
|
| 158 |
N |
L |
-0.9033 |
|
| 159 |
S |
L |
-1.3330 |
|
| 160 |
Q |
L |
-2.1722 |
|
| 161 |
E |
L |
-2.0671 |
|
| 162 |
S |
L |
-1.2070 |
|
| 163 |
V |
L |
-0.7741 |
|
| 164 |
T |
L |
-1.3042 |
|
| 165 |
E |
L |
-2.3862 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.5155 |
|
| 168 |
S |
L |
-2.5865 |
|
| 169 |
K |
L |
-2.8975 |
|
| 170 |
D |
L |
-2.2827 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-1.0248 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.3582 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5189 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.5927 |
|
| 181 |
L |
L |
-0.9274 |
|
| 182 |
S |
L |
-1.3648 |
|
| 183 |
K |
L |
-2.4797 |
|
| 184 |
A |
L |
-2.3028 |
|
| 185 |
D |
L |
-3.2999 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-4.1761 |
|
| 188 |
K |
L |
-4.1404 |
|
| 189 |
H |
L |
-3.4697 |
|
| 190 |
K |
L |
-3.6338 |
|
| 191 |
V |
L |
-1.8641 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.7053 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2281 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7719 |
|
| 200 |
G |
L |
-0.4827 |
|
| 201 |
L |
L |
-0.2684 |
|
| 202 |
S |
L |
-0.4683 |
|
| 203 |
S |
L |
-0.4525 |
|
| 204 |
P |
L |
-0.6145 |
|
| 205 |
V |
L |
-0.0826 |
|
| 206 |
T |
L |
-0.3353 |
|
| 207 |
K |
L |
-0.1861 |
|
| 208 |
S |
L |
-0.4560 |
|
| 209 |
F |
L |
-0.9312 |
|
| 210 |
N |
L |
-2.5449 |
|
| 211 |
R |
L |
-3.4940 |
|