Project name: 3c08:L
Status: done
submitted: 2019-03-20 20:07:11, status changed: 2019-03-20 20:17:43
Settings
|
Chain sequence(s)
|
L: MTQSPSSLSASVGDRVTITCSASVTYMYWYQQKPGKAPKLLIYDTSNLASGVPSRFSGSGSGTDYTFTISSLQPEDIATYYCQQWSSHIFTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.1461
-
Maximal score value
-
3.0398
-
Average score
-
-0.7371
-
Total score value
-
-151.8463
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 4 |
M |
L |
0.4004 |
|
| 5 |
T |
L |
-0.0845 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.5420 |
|
| 8 |
P |
L |
-0.7240 |
|
| 9 |
S |
L |
-1.0501 |
|
| 10 |
S |
L |
-1.0674 |
|
| 11 |
L |
L |
-0.7900 |
|
| 12 |
S |
L |
-1.1682 |
|
| 13 |
A |
L |
-1.0481 |
|
| 14 |
S |
L |
-0.7755 |
|
| 15 |
V |
L |
0.4054 |
|
| 16 |
G |
L |
-0.5861 |
|
| 17 |
D |
L |
-1.7735 |
|
| 18 |
R |
L |
-2.2605 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6125 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.6145 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
S |
L |
-0.7819 |
|
| 25 |
A |
L |
-0.5505 |
|
| 28 |
S |
L |
-0.1839 |
|
| 29 |
V |
L |
0.3259 |
|
| 30 |
T |
L |
0.0309 |
|
| 31 |
Y |
L |
0.2437 |
|
| 32 |
M |
L |
0.0000 |
|
| 33 |
Y |
L |
0.6563 |
|
| 34 |
W |
L |
0.0000 |
|
| 35 |
Y |
L |
0.0124 |
|
| 36 |
Q |
L |
0.0000 |
|
| 37 |
Q |
L |
-1.5524 |
|
| 38 |
K |
L |
-2.0829 |
|
| 39 |
P |
L |
-1.5960 |
|
| 40 |
G |
L |
-1.7538 |
|
| 41 |
K |
L |
-2.3785 |
|
| 42 |
A |
L |
-1.4975 |
|
| 43 |
P |
L |
-1.4493 |
|
| 44 |
K |
L |
-1.7694 |
|
| 45 |
L |
L |
-0.0346 |
|
| 46 |
L |
L |
0.0000 |
|
| 47 |
I |
L |
0.0000 |
|
| 48 |
Y |
L |
-0.0323 |
|
| 49 |
D |
L |
-0.8035 |
|
| 50 |
T |
L |
-0.5827 |
|
| 51 |
S |
L |
-0.8388 |
|
| 52 |
N |
L |
-1.1320 |
|
| 53 |
L |
L |
-0.1981 |
|
| 54 |
A |
L |
-0.2802 |
|
| 55 |
S |
L |
-0.3267 |
|
| 56 |
G |
L |
-0.4384 |
|
| 57 |
V |
L |
-0.1495 |
|
| 58 |
P |
L |
-0.2728 |
|
| 59 |
S |
L |
-0.3599 |
|
| 60 |
R |
L |
-0.6741 |
|
| 61 |
F |
L |
0.0000 |
|
| 62 |
S |
L |
-0.4445 |
|
| 63 |
G |
L |
0.0000 |
|
| 64 |
S |
L |
-0.9421 |
|
| 65 |
G |
L |
-1.1035 |
|
| 66 |
S |
L |
-1.0483 |
|
| 67 |
G |
L |
-1.0856 |
|
| 68 |
T |
L |
-1.2350 |
|
| 69 |
D |
L |
-2.1383 |
|
| 70 |
Y |
L |
0.0000 |
|
| 71 |
T |
L |
-0.6875 |
|
| 72 |
F |
L |
0.0000 |
|
| 73 |
T |
L |
-0.5721 |
|
| 74 |
I |
L |
0.0000 |
|
| 75 |
S |
L |
-1.3899 |
|
| 76 |
S |
L |
-1.0505 |
|
| 77 |
L |
L |
0.0000 |
|
| 78 |
Q |
L |
-0.7890 |
|
| 79 |
P |
L |
-1.6105 |
|
| 80 |
E |
L |
-2.4139 |
|
| 81 |
D |
L |
0.0000 |
|
| 82 |
I |
L |
0.0000 |
|
| 83 |
A |
L |
0.0000 |
|
| 84 |
T |
L |
0.0000 |
|
| 85 |
Y |
L |
0.0000 |
|
| 86 |
Y |
L |
-0.1344 |
|
| 87 |
C |
L |
0.0000 |
|
| 88 |
Q |
L |
0.0000 |
|
| 89 |
Q |
L |
1.3445 |
|
| 90 |
W |
L |
1.5498 |
|
| 91 |
S |
L |
0.9178 |
|
| 92 |
S |
L |
0.3657 |
|
| 93 |
H |
L |
0.3695 |
|
| 94 |
I |
L |
2.4769 |
|
| 95 |
F |
L |
3.0398 |
|
| 96 |
T |
L |
1.9107 |
|
| 97 |
F |
L |
1.5347 |
|
| 98 |
G |
L |
0.0511 |
|
| 99 |
Q |
L |
-1.0723 |
|
| 100 |
G |
L |
0.0000 |
|
| 101 |
T |
L |
0.0000 |
|
| 102 |
K |
L |
-2.2677 |
|
| 103 |
V |
L |
0.0000 |
|
| 104 |
E |
L |
-1.4487 |
|
| 105 |
I |
L |
0.0000 |
|
| 106 |
K |
L |
-1.6435 |
|
| 107 |
R |
L |
-1.0120 |
|
| 108 |
T |
L |
-0.0931 |
|
| 109 |
V |
L |
0.4961 |
|
| 110 |
A |
L |
0.1720 |
|
| 111 |
A |
L |
-0.1248 |
|
| 112 |
P |
L |
0.0000 |
|
| 113 |
S |
L |
-0.0374 |
|
| 114 |
V |
L |
0.0000 |
|
| 115 |
F |
L |
1.1700 |
|
| 116 |
I |
L |
1.2221 |
|
| 117 |
F |
L |
1.4755 |
|
| 118 |
P |
L |
-0.1346 |
|
| 119 |
P |
L |
-0.5963 |
|
| 120 |
S |
L |
-1.7736 |
|
| 121 |
D |
L |
-3.2447 |
|
| 122 |
E |
L |
-3.4331 |
|
| 123 |
Q |
L |
-2.4207 |
|
| 124 |
L |
L |
-2.4670 |
|
| 125 |
K |
L |
-2.9903 |
|
| 126 |
S |
L |
-1.9292 |
|
| 127 |
G |
L |
-1.3741 |
|
| 128 |
T |
L |
-1.1073 |
|
| 129 |
A |
L |
0.0000 |
|
| 130 |
S |
L |
-0.0551 |
|
| 131 |
V |
L |
0.0000 |
|
| 132 |
V |
L |
0.6999 |
|
| 133 |
C |
L |
0.0000 |
|
| 134 |
L |
L |
0.5119 |
|
| 135 |
L |
L |
0.0000 |
|
| 136 |
N |
L |
-0.4474 |
|
| 137 |
N |
L |
-1.1880 |
|
| 138 |
F |
L |
0.0000 |
|
| 139 |
Y |
L |
0.0000 |
|
| 140 |
P |
L |
-1.8137 |
|
| 141 |
R |
L |
-2.8882 |
|
| 142 |
E |
L |
-3.1958 |
|
| 143 |
A |
L |
-2.2226 |
|
| 144 |
K |
L |
-2.0754 |
|
| 145 |
V |
L |
-1.0365 |
|
| 146 |
Q |
L |
-0.6686 |
|
| 147 |
W |
L |
0.0000 |
|
| 148 |
K |
L |
-0.5942 |
|
| 149 |
V |
L |
0.0000 |
|
| 150 |
D |
L |
-1.9886 |
|
| 151 |
N |
L |
-1.5111 |
|
| 152 |
A |
L |
-0.2482 |
|
| 153 |
L |
L |
0.6683 |
|
| 154 |
Q |
L |
-0.3578 |
|
| 155 |
S |
L |
-0.8998 |
|
| 156 |
G |
L |
-1.5410 |
|
| 157 |
N |
L |
-1.9099 |
|
| 158 |
S |
L |
-1.9750 |
|
| 159 |
Q |
L |
-2.5346 |
|
| 160 |
E |
L |
-2.3601 |
|
| 161 |
S |
L |
-1.3503 |
|
| 162 |
V |
L |
-0.7384 |
|
| 163 |
T |
L |
-1.1800 |
|
| 164 |
E |
L |
-2.4410 |
|
| 165 |
Q |
L |
0.0000 |
|
| 166 |
D |
L |
-2.1681 |
|
| 167 |
S |
L |
-2.3018 |
|
| 168 |
K |
L |
-2.5192 |
|
| 169 |
D |
L |
-1.7787 |
|
| 170 |
S |
L |
0.0000 |
|
| 171 |
T |
L |
0.0000 |
|
| 172 |
Y |
L |
0.0000 |
|
| 173 |
S |
L |
-0.9136 |
|
| 174 |
L |
L |
0.0000 |
|
| 175 |
S |
L |
-0.5264 |
|
| 176 |
S |
L |
0.0000 |
|
| 177 |
T |
L |
-0.8570 |
|
| 178 |
L |
L |
0.0000 |
|
| 179 |
T |
L |
-0.7888 |
|
| 180 |
L |
L |
-0.8990 |
|
| 181 |
S |
L |
-1.0266 |
|
| 182 |
K |
L |
-2.0583 |
|
| 183 |
A |
L |
-1.9516 |
|
| 184 |
D |
L |
-2.7329 |
|
| 185 |
Y |
L |
0.0000 |
|
| 186 |
E |
L |
-4.1461 |
|
| 187 |
K |
L |
-4.0429 |
|
| 188 |
H |
L |
-3.6516 |
|
| 189 |
K |
L |
-3.9433 |
|
| 190 |
V |
L |
-2.0374 |
|
| 191 |
Y |
L |
0.0000 |
|
| 192 |
A |
L |
0.0000 |
|
| 193 |
C |
L |
0.0000 |
|
| 194 |
E |
L |
-0.7748 |
|
| 195 |
V |
L |
0.0000 |
|
| 196 |
T |
L |
-1.1569 |
|
| 197 |
H |
L |
0.0000 |
|
| 198 |
Q |
L |
-1.6467 |
|
| 199 |
G |
L |
-0.2967 |
|
| 200 |
L |
L |
-0.1577 |
|
| 201 |
S |
L |
-0.4160 |
|
| 202 |
S |
L |
-0.4227 |
|
| 203 |
P |
L |
-0.5946 |
|
| 204 |
V |
L |
-0.0728 |
|
| 205 |
T |
L |
-0.4344 |
|
| 206 |
K |
L |
-0.3658 |
|
| 207 |
S |
L |
-0.3046 |
|
| 208 |
F |
L |
-0.8962 |
|
| 209 |
N |
L |
-2.6573 |
|
| 210 |
R |
L |
-3.8407 |
|
| 211 |
G |
L |
-3.6630 |
|