Project name: 3532f76b5e245a8

Chain sequence(s)	A: KEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.5569
• Maximal score value: 0.1183
• Average score: -1.3648
• Total score value: -249.7652

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
8	K	A	-2.3026
9	E	A	-1.8889
10	P	A	-1.8116
11	E	A	-2.5012
12	Q	A	-1.3802
13	L	A	-0.6108
14	R	A	0.0000
15	K	A	-0.7558
16	L	A	0.0000
17	F	A	0.0000
18	I	A	0.0000
19	G	A	-0.8240
20	G	A	-0.5652
21	L	A	0.0000
22	S	A	-0.6797
23	F	A	0.1183
24	E	A	-1.3594
25	T	A	0.0000
26	T	A	-1.5247
27	D	A	-1.9192
28	E	A	-2.6266
29	S	A	-2.1625
30	L	A	0.0000
31	R	A	-2.9297
32	S	A	-2.2298
33	H	A	-2.2218
34	F	A	0.0000
35	E	A	-2.7755
36	Q	A	-2.2176
37	W	A	-1.2684
38	G	A	-1.2641
39	T	A	-0.9630
40	L	A	-0.9756
41	T	A	-0.8227
42	D	A	-0.9455
43	C	A	0.0000
44	V	A	-0.6355
45	V	A	0.0000
46	M	A	0.0000
47	R	A	-2.5876
48	D	A	-2.9719
49	P	A	-2.2161
50	N	A	-2.6052
51	T	A	-2.4891
52	K	A	-3.6513
53	R	A	-3.3147
54	S	A	0.0000
55	R	A	-1.8908
56	G	A	-0.7474
57	F	A	0.0000
58	G	A	0.0000
59	F	A	0.0000
60	V	A	0.0000
61	T	A	0.0000
62	Y	A	0.0000
63	A	A	-1.0847
64	T	A	-1.4369
65	V	A	-1.4774
66	E	A	-2.0239
67	E	A	-1.7065
68	V	A	0.0000
69	D	A	-1.4195
70	A	A	-1.2793
71	A	A	0.0000
72	M	A	0.0000
73	N	A	-1.5954
74	A	A	-0.9482
75	R	A	-1.4468
76	P	A	-1.2351
77	H	A	0.0000
78	K	A	-2.5100
79	V	A	0.0000
80	D	A	-2.3785
81	G	A	-2.0125
82	R	A	-2.0023
83	V	A	-1.1384
84	V	A	0.0000
85	E	A	-1.9924
86	P	A	0.0000
87	K	A	-0.8026
88	R	A	0.0000
89	A	A	0.0000
90	V	A	0.0000
91	S	A	-1.8442
92	R	A	-2.9462
93	E	A	-3.5118
94	D	A	-3.0029
95	S	A	-2.7483
96	Q	A	-3.3738
97	R	A	-3.5006
98	P	A	-1.7448
99	G	A	-1.3652
100	A	A	-1.2707
101	H	A	-0.6957
102	L	A	0.0582
103	T	A	-0.3296
104	V	A	-0.7348
105	K	A	-1.9852
106	K	A	-1.9637
107	I	A	0.0000
108	F	A	-0.5338
109	V	A	0.0000
110	G	A	0.0000
111	G	A	-2.0134
112	I	A	0.0000
113	K	A	-4.0103
114	E	A	-4.5569
115	D	A	-3.9553
116	T	A	0.0000
117	E	A	-3.8865
118	E	A	-3.2285
119	H	A	-3.0823
120	H	A	-2.9806
121	L	A	0.0000
122	R	A	-3.6406
123	D	A	-3.4874
124	Y	A	-2.0922
125	F	A	0.0000
126	E	A	-3.4892
127	Q	A	-2.6461
128	Y	A	-1.4644
129	G	A	-2.3678
130	K	A	-3.1889
131	I	A	-2.5858
132	E	A	-2.3770
133	V	A	-1.0106
134	I	A	-1.0420
135	E	A	-0.9964
136	I	A	-1.1011
137	M	A	-0.9919
138	T	A	-2.4165
139	D	A	-2.7681
140	R	A	-2.9182
141	G	A	-1.9206
142	S	A	-2.0105
143	G	A	-2.4086
144	K	A	-3.4509
145	K	A	-3.6124
146	R	A	-3.2177
147	G	A	-2.4044
148	F	A	-1.0257
149	A	A	0.0000
150	F	A	0.0406
151	V	A	0.0000
152	T	A	0.0000
153	F	A	0.0000
154	D	A	-2.8443
155	D	A	-2.0970
156	H	A	-1.2608
157	D	A	0.0000
158	S	A	0.0000
159	V	A	0.0000
160	D	A	0.0000
161	K	A	-0.2675
162	I	A	0.0000
163	V	A	-0.3354
164	I	A	-0.0448
165	Q	A	-0.4454
166	K	A	-1.4041
167	Y	A	-0.2661
168	H	A	0.0000
169	T	A	-1.2567
170	V	A	0.0000
171	N	A	-2.6098
172	G	A	-1.5998
173	H	A	-2.1025
174	N	A	-2.1943
175	C	A	0.0000
176	E	A	-2.2523
177	V	A	-1.2214
178	R	A	-1.6143
179	K	A	0.0000
180	A	A	-0.7727
181	L	A	-0.8698
182	S	A	-1.3430
183	K	A	-2.3234
184	Q	A	-2.2352
185	E	A	-1.7243
186	M	A	-0.9351
187	A	A	-0.8893
188	S	A	-0.9258
189	A	A	-0.8701
190	S	A	-0.2509