Project name: 3fzu

Chain sequence(s)	A: DIQMTQSPSSLSASVGDRVTITCRASQDIRYYLNWYQQKPGKAPKLLIYVASSLQSGVPSRFSGSGSGTEFTLTVSSLQPEDFATYYCLQVYSTPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEEVQLVESGGGLAKPGGSLRLSCAASGFRFTFNNYYMDWVRQAPGQGLEWVSRISSSGDPTWYADSVKGRFTISRENAKNTLFLQMNSLRAEDTAVYYCASLTTGSDSWGQGVLVTVSSASTKGPSVFPLAPSSKSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5612
• Maximal score value: 1.1314
• Average score: -0.7704
• Total score value: -329.752

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-2.1403
2	I	A	-1.5021
3	Q	A	-1.7969
4	M	A	0.0000
5	T	A	-1.2589
6	Q	A	0.0000
7	S	A	-0.8343
8	P	A	-0.6129
9	S	A	-0.8140
10	S	A	-0.7849
11	L	A	-0.3988
12	S	A	-0.8261
13	A	A	0.0000
14	S	A	-1.2833
15	V	A	-0.7396
16	G	A	-1.0568
17	D	A	-2.4407
18	R	A	-2.6099
19	V	A	-1.1424
20	T	A	-0.3882
21	I	A	0.0000
22	T	A	-0.8312
23	C	A	0.0000
24	R	A	-2.8440
25	A	A	0.0000
26	S	A	-2.1373
27	Q	A	-2.8777
28	D	A	-2.5709
29	I	A	0.0000
30	R	A	-2.2722
31	Y	A	-0.1810
32	Y	A	0.6447
33	L	A	0.0000
34	N	A	0.0000
35	W	A	0.0000
36	Y	A	0.0000
37	Q	A	0.0000
38	Q	A	0.0000
39	K	A	-1.6399
40	P	A	-1.2951
41	G	A	-1.6937
42	K	A	-2.4411
43	A	A	-1.6296
44	P	A	0.0000
45	K	A	-1.4937
46	L	A	0.0000
47	L	A	0.0000
48	I	A	0.0000
49	Y	A	0.3948
50	V	A	0.0000
51	A	A	0.0000
52	S	A	-0.0460
53	S	A	0.0237
54	L	A	0.3383
55	Q	A	-0.2681
56	S	A	-0.2068
57	G	A	-0.1380
58	V	A	-0.2129
59	P	A	-0.3708
60	S	A	-0.4531
61	R	A	-0.9028
62	F	A	0.0000
63	S	A	-0.3522
64	G	A	-0.2640
65	S	A	-0.6083
66	G	A	-1.4225
67	S	A	-1.7019
68	G	A	-2.5223
69	T	A	-2.6401
70	E	A	-3.0157
71	F	A	0.0000
72	T	A	-0.8631
73	L	A	0.0000
74	T	A	-0.5451
75	V	A	0.0000
76	S	A	-1.5258
77	S	A	-1.4544
78	L	A	0.0000
79	Q	A	-1.4096
80	P	A	-2.3007
81	E	A	-2.6761
82	D	A	0.0000
83	F	A	0.0000
84	A	A	0.0000
85	T	A	-0.8240
86	Y	A	0.0000
87	Y	A	0.0000
88	C	A	0.0000
89	L	A	0.0000
90	Q	A	0.0000
91	V	A	1.1248
92	Y	A	0.8166
93	S	A	0.2066
94	T	A	-0.1045
95	P	A	-0.5268
96	R	A	0.0000
97	T	A	-0.5154
98	F	A	-0.3328
99	G	A	0.0000
100	Q	A	-1.5255
101	G	A	-1.1657
102	T	A	-1.0351
103	K	A	-1.3534
104	V	A	0.0000
105	E	A	-1.5267
106	I	A	0.0000
107	K	A	-1.8173
108	R	A	-1.2182
109	T	A	-0.2165
110	V	A	0.6586
111	A	A	-0.0124
112	A	A	-0.2656
113	P	A	0.0000
114	S	A	-0.3087
115	V	A	0.0637
116	F	A	0.1351
117	I	A	0.1293
118	F	A	0.0000
119	P	A	-0.3794
120	P	A	-0.7411
121	S	A	-1.5419
122	D	A	-2.7933
123	E	A	-2.7589
124	Q	A	0.0000
125	L	A	-1.9694
126	K	A	-2.8169
127	S	A	-1.7911
128	G	A	-1.2401
129	T	A	-1.1917
130	A	A	-1.0908
131	S	A	0.0000
132	V	A	0.0000
133	V	A	0.0000
134	C	A	0.0000
135	L	A	0.0000
136	L	A	0.0000
137	N	A	-0.4669
138	N	A	-1.6705
139	F	A	0.0000
140	Y	A	-1.2610
141	P	A	-1.5730
142	R	A	-2.2491
143	E	A	-3.0109
144	A	A	-1.9392
145	K	A	-2.0827
146	V	A	0.0000
147	Q	A	-0.7813
148	W	A	0.0000
149	K	A	-0.7731
150	V	A	0.0000
151	D	A	-1.8137
152	N	A	-1.4040
153	A	A	-0.3266
154	L	A	0.4740
155	Q	A	-0.5235
156	S	A	-0.9716
157	G	A	-1.0910
158	N	A	-1.7649
159	S	A	-1.6373
160	Q	A	-1.6316
161	E	A	-1.9934
162	S	A	-0.5406
163	V	A	-0.1663
164	T	A	-0.7825
165	E	A	-1.6781
166	Q	A	0.0000
167	D	A	-2.5143
168	S	A	-2.7552
169	K	A	-3.3170
170	D	A	-3.4473
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	0.0000
175	L	A	0.4021
176	S	A	0.0000
177	S	A	-0.8970
178	T	A	0.0000
179	L	A	0.0000
180	T	A	-0.4670
181	L	A	-0.7225
182	S	A	0.0000
183	K	A	-2.1235
184	A	A	-1.8135
185	D	A	-2.2975
186	Y	A	0.0000
187	E	A	-3.5612
188	K	A	-3.5149
189	H	A	-2.8894
190	K	A	-2.6707
191	V	A	-1.0822
192	Y	A	0.0000
193	A	A	-0.6519
194	C	A	0.0000
195	E	A	-1.0358
196	V	A	0.0000
197	T	A	-1.1097
198	H	A	0.0000
199	Q	A	-1.7707
200	G	A	-0.5909
201	L	A	-0.1938
202	S	A	-0.4843
203	S	A	-0.3873
204	P	A	-0.4037
205	V	A	-0.0404
206	T	A	-0.5428
207	K	A	-0.6524
208	S	A	-0.3937
209	F	A	-0.4785
210	N	A	-1.3951
211	R	A	-1.5816
212	G	A	-1.0244
1	E	A	-1.8731
2	V	A	-1.2423
3	Q	A	-1.2384
4	L	A	0.0000
5	V	A	0.1595
6	E	A	-0.2080
7	S	A	-0.4911
8	G	A	-1.1385
9	G	A	-1.0918
10	G	A	-0.6783
11	L	A	-0.3441
12	A	A	0.0000
13	K	A	-2.2007
14	P	A	-1.9252
15	G	A	-1.6186
16	G	A	-1.4368
17	S	A	-1.4559
18	L	A	-1.2319
19	R	A	-2.1711
20	L	A	0.0000
21	S	A	-0.4834
22	C	A	0.0000
23	A	A	-0.5783
24	A	A	-0.2283
25	S	A	-0.8177
26	G	A	-1.1008
27	F	A	-0.7536
28	R	A	-1.1771
29	F	A	-0.0525
30	T	A	-0.6176
31	F	A	0.0000
32	N	A	-1.7907
33	N	A	-1.4303
34	Y	A	0.0000
35	Y	A	-0.0239
36	M	A	0.0000
37	D	A	0.0000
38	W	A	0.0000
39	V	A	0.0000
40	R	A	0.0000
41	Q	A	-0.6490
42	A	A	-1.0735
43	P	A	-1.0946
44	G	A	-1.2304
45	Q	A	-1.8651
46	G	A	-1.3288
47	L	A	0.0000
48	E	A	-0.8812
49	W	A	0.0000
50	V	A	0.0000
51	S	A	0.0000
52	R	A	-0.3275
53	I	A	0.0000
54	S	A	0.0000
55	S	A	-1.1443
56	S	A	-1.5809
57	G	A	-1.6239
58	D	A	-2.0366
59	P	A	-1.3878
60	T	A	-0.6634
61	W	A	-0.2986
62	Y	A	-0.8955
63	A	A	-1.6569
64	D	A	-2.4859
65	S	A	-1.8239
66	V	A	0.0000
67	K	A	-2.5660
68	G	A	-1.7868
69	R	A	-1.6164
70	F	A	0.0000
71	T	A	-0.8013
72	I	A	0.0000
73	S	A	-0.9145
74	R	A	-1.8165
75	E	A	-2.8466
76	N	A	-2.9630
77	A	A	-2.0175
78	K	A	-2.8243
79	N	A	-2.5120
80	T	A	0.0000
81	L	A	0.0000
82	F	A	-0.4636
83	L	A	0.0000
84	Q	A	-1.2254
85	M	A	0.0000
86	N	A	-1.5801
87	S	A	-1.3868
88	L	A	0.0000
89	R	A	-2.4540
90	A	A	-1.8040
91	E	A	-2.2870
92	D	A	0.0000
93	T	A	-0.7039
94	A	A	0.0000
95	V	A	0.3706
96	Y	A	0.0000
97	Y	A	0.0000
98	C	A	0.0000
99	A	A	0.0000
100	S	A	0.0000
101	L	A	0.1392
102	T	A	-0.0689
103	T	A	-0.2667
104	G	A	-0.5535
105	S	A	-0.3715
106	D	A	-0.5291
107	S	A	-0.3867
108	W	A	0.0000
109	G	A	-0.6651
110	Q	A	-1.5640
111	G	A	0.0000
112	V	A	-0.0622
113	L	A	0.1631
114	V	A	0.0000
115	T	A	0.0000
116	V	A	0.0000
117	S	A	-1.0123
118	S	A	-0.9915
119	A	A	-0.6841
120	S	A	-0.7948
121	T	A	-0.9607
122	K	A	-1.7247
123	G	A	-1.8105
124	P	A	0.0000
125	S	A	-0.4103
126	V	A	0.0000
127	F	A	0.0000
128	P	A	-1.2391
129	L	A	0.0000
130	A	A	-0.4787
131	P	A	-0.2601
132	S	A	-0.6342
133	S	A	-1.2618
134	K	A	-2.1732
135	S	A	-1.4895
138	G	A	-1.3998
139	G	A	-1.1618
140	T	A	-0.7123
141	A	A	-0.5657
142	A	A	0.0000
143	L	A	0.0000
144	G	A	0.0000
145	C	A	0.0000
146	L	A	0.0000
147	V	A	0.0000
148	K	A	0.0000
149	D	A	-0.6795
150	Y	A	0.0000
151	F	A	0.0000
152	P	A	0.0000
153	E	A	-0.9190
154	P	A	-0.8576
155	V	A	0.0000
156	T	A	-0.6875
157	V	A	-0.0983
158	S	A	-0.2873
159	W	A	0.0000
160	N	A	-0.7479
161	S	A	-0.6399
162	G	A	-0.4518
163	A	A	-0.0907
164	L	A	0.2513
165	T	A	-0.0734
166	S	A	-0.1427
167	G	A	-0.3149
168	V	A	-0.0004
169	H	A	-0.5819
170	T	A	-0.1570
171	F	A	0.0000
172	P	A	-0.3254
173	A	A	0.0150
174	V	A	0.2771
175	L	A	1.1314
176	Q	A	0.1852
177	S	A	-0.2515
178	S	A	-0.2679
179	G	A	-0.0161
180	L	A	-0.0508
181	Y	A	0.2236
182	S	A	0.0000
183	L	A	0.0000
184	S	A	0.0000
185	S	A	0.0000
186	V	A	0.0000
187	V	A	0.0000
188	T	A	-0.1424
189	V	A	0.0766
190	P	A	-0.4534
191	S	A	-0.9769
192	S	A	-0.7432
193	S	A	-0.3860
194	L	A	-0.5650
195	G	A	-0.7112
196	T	A	-0.7429
197	Q	A	-1.1573
198	T	A	-1.3119
199	Y	A	0.0000
200	I	A	-1.2069
201	C	A	0.0000
202	N	A	-1.4154
203	V	A	0.0000
204	N	A	-1.9962
205	H	A	0.0000
206	K	A	-2.5561
207	P	A	-1.5903
208	S	A	-1.9232
209	N	A	-2.4893
210	T	A	-2.1536
211	K	A	-2.7177
212	V	A	-1.6967
213	D	A	-2.3973
214	K	A	-2.2095
215	K	A	-2.6142
216	V	A	0.0000
217	E	A	-2.3980
218	P	A	-1.2665