Project name: 4i77:L
Status: done
submitted: 2019-03-20 20:18:21, status changed: 2019-03-20 20:27:49
Settings
|
Chain sequence(s)
|
L: DIVMTQSPDSLSVSLGERATINCRASKSVDSYGNSFMHWYQQKPGQPPKLLIYLASNLESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQNNEDPRTFGGGTKVEIKRTVAAPSVFIFPPSDEEQLKSGTASVVCLLNNFYPREAKVQQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACCEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.1038
-
Maximal score value
-
1.579
-
Average score
-
-0.905
-
Total score value
-
-197.2804
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.6380 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
V |
L |
0.6336 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.8213 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-1.6662 |
|
| 8 |
P |
L |
-1.4396 |
|
| 9 |
D |
L |
-2.2105 |
|
| 10 |
S |
L |
-1.1697 |
|
| 11 |
L |
L |
-0.6574 |
|
| 12 |
S |
L |
-0.4688 |
|
| 13 |
V |
L |
-0.9379 |
|
| 14 |
S |
L |
-0.8987 |
|
| 15 |
L |
L |
0.0226 |
|
| 16 |
G |
L |
-1.0174 |
|
| 17 |
E |
L |
-2.2383 |
|
| 18 |
R |
L |
-2.5709 |
|
| 19 |
A |
L |
0.0000 |
|
| 20 |
T |
L |
-0.7852 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
N |
L |
-2.2618 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.8864 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-1.2797 |
|
| 27 |
K |
L |
-2.3538 |
|
| 27A |
S |
L |
-1.8893 |
|
| 27B |
V |
L |
0.0000 |
|
| 27C |
D |
L |
-1.3055 |
|
| 27D |
S |
L |
-0.4216 |
|
| 28 |
Y |
L |
0.5628 |
|
| 29 |
G |
L |
-0.6029 |
|
| 30 |
N |
L |
-1.1771 |
|
| 31 |
S |
L |
0.0000 |
|
| 32 |
F |
L |
-0.4759 |
|
| 33 |
M |
L |
0.0000 |
|
| 34 |
H |
L |
0.4535 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.1254 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.2656 |
|
| 39 |
K |
L |
-1.8034 |
|
| 40 |
P |
L |
-1.4973 |
|
| 41 |
G |
L |
-1.5204 |
|
| 42 |
Q |
L |
-2.0630 |
|
| 43 |
P |
L |
-1.4857 |
|
| 44 |
P |
L |
-1.3032 |
|
| 45 |
K |
L |
-1.5827 |
|
| 46 |
L |
L |
-0.2131 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.6648 |
|
| 50 |
L |
L |
0.1868 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.4400 |
|
| 53 |
N |
L |
-0.4977 |
|
| 54 |
L |
L |
-0.4946 |
|
| 55 |
E |
L |
-0.9126 |
|
| 56 |
S |
L |
-0.8482 |
|
| 57 |
G |
L |
-0.9228 |
|
| 58 |
V |
L |
0.0000 |
|
| 59 |
P |
L |
-1.2611 |
|
| 60 |
D |
L |
-2.1373 |
|
| 61 |
R |
L |
-1.6755 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.8137 |
|
| 64 |
G |
L |
-0.4612 |
|
| 65 |
S |
L |
-0.9622 |
|
| 66 |
G |
L |
-1.4704 |
|
| 67 |
S |
L |
-1.5011 |
|
| 68 |
G |
L |
-1.6923 |
|
| 69 |
T |
L |
-2.1846 |
|
| 70 |
D |
L |
-2.9657 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-1.3760 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.7743 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.7882 |
|
| 77 |
S |
L |
-1.4676 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.3688 |
|
| 80 |
A |
L |
-1.5354 |
|
| 81 |
E |
L |
-1.8615 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
V |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
V |
L |
-0.3346 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.1973 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
N |
L |
-2.4114 |
|
| 92 |
N |
L |
-2.5888 |
|
| 93 |
E |
L |
-4.1038 |
|
| 94 |
D |
L |
-3.9996 |
|
| 95 |
P |
L |
-3.2303 |
|
| 96 |
R |
L |
-3.0644 |
|
| 97 |
T |
L |
-0.9202 |
|
| 98 |
F |
L |
1.1479 |
|
| 99 |
G |
L |
0.4971 |
|
| 100 |
G |
L |
-0.2318 |
|
| 101 |
G |
L |
-0.5678 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-0.7660 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-0.9393 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.1916 |
|
| 108 |
R |
L |
-0.6191 |
|
| 109 |
T |
L |
0.0421 |
|
| 110 |
V |
L |
0.5256 |
|
| 111 |
A |
L |
-0.0579 |
|
| 112 |
A |
L |
-0.2006 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1284 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.2290 |
|
| 117 |
I |
L |
1.2445 |
|
| 118 |
F |
L |
1.5790 |
|
| 119 |
P |
L |
0.0003 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.7145 |
|
| 122 |
D |
L |
-3.1957 |
|
| 123 |
E |
L |
-3.4130 |
|
| 124 |
Q |
L |
-2.4902 |
|
| 125 |
L |
L |
-2.6095 |
|
| 126 |
K |
L |
-3.0624 |
|
| 127 |
S |
L |
-1.9214 |
|
| 128 |
G |
L |
-1.4045 |
|
| 129 |
T |
L |
-1.2792 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0309 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7671 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5285 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5505 |
|
| 138 |
N |
L |
-1.3023 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.7595 |
|
| 142 |
R |
L |
-3.0950 |
|
| 143 |
E |
L |
-3.2840 |
|
| 144 |
A |
L |
-2.4265 |
|
| 145 |
K |
L |
-2.5533 |
|
| 146 |
V |
L |
0.0000 |
|
| 147 |
Q |
L |
-0.6301 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5142 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.7967 |
|
| 152 |
N |
L |
-1.4454 |
|
| 153 |
A |
L |
-0.1967 |
|
| 154 |
L |
L |
0.8095 |
|
| 155 |
Q |
L |
-0.0185 |
|
| 156 |
S |
L |
-0.4915 |
|
| 157 |
G |
L |
-0.9886 |
|
| 158 |
N |
L |
-0.9562 |
|
| 159 |
S |
L |
-1.4156 |
|
| 160 |
Q |
L |
-2.2940 |
|
| 161 |
E |
L |
-2.3294 |
|
| 162 |
S |
L |
-1.1340 |
|
| 163 |
V |
L |
-0.6376 |
|
| 164 |
T |
L |
-1.0416 |
|
| 165 |
E |
L |
-1.9770 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.2657 |
|
| 168 |
S |
L |
-2.3151 |
|
| 169 |
K |
L |
-2.6582 |
|
| 170 |
D |
L |
-2.0274 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9112 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4406 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5932 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.5880 |
|
| 181 |
L |
L |
-0.8758 |
|
| 182 |
S |
L |
-1.3030 |
|
| 183 |
K |
L |
-2.5291 |
|
| 184 |
A |
L |
-2.1687 |
|
| 185 |
D |
L |
-2.8859 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.7218 |
|
| 188 |
K |
L |
-3.7477 |
|
| 189 |
H |
L |
-2.9301 |
|
| 190 |
K |
L |
-2.8225 |
|
| 191 |
V |
L |
-1.0844 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.9589 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2665 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7306 |
|
| 200 |
G |
L |
-0.3846 |
|
| 201 |
L |
L |
-0.2296 |
|
| 202 |
S |
L |
-0.4817 |
|
| 203 |
S |
L |
-0.4179 |
|
| 204 |
P |
L |
-0.5632 |
|
| 205 |
V |
L |
-0.0107 |
|
| 206 |
T |
L |
-0.4023 |
|
| 207 |
K |
L |
-0.3895 |
|
| 208 |
S |
L |
-0.2141 |
|
| 209 |
F |
L |
0.0000 |
|
| 210 |
N |
L |
-1.3324 |
|
| 211 |
R |
L |
-2.2008 |
|
| 212 |
G |
L |
-1.8668 |
|
| 213 |
E |
L |
-2.0754 |
|
| 214 |
C |
L |
-0.5300 |
|