Project name: 379dd139172c47c

Chain sequence(s)	A: SKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFVQCFSRYPDHMKRHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLEFVTAAGI
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.9632
• Maximal score value: 1.2374
• Average score: -0.9312
• Total score value: -209.5257

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	S	A	-1.7529
3	K	A	-1.9422
4	G	A	0.0000
5	E	A	-2.6716
6	E	A	-2.5949
7	L	A	-1.2087
8	F	A	0.0000
9	T	A	-0.6353
10	G	A	0.4437
11	V	A	1.2374
12	V	A	0.0000
13	P	A	-0.9706
14	I	A	0.0000
15	L	A	-0.9837
16	V	A	0.0000
17	E	A	-1.9112
18	L	A	0.0000
19	D	A	-3.3257
20	G	A	0.0000
21	D	A	-2.4254
22	V	A	0.0000
23	N	A	-2.0488
24	G	A	-1.6208
25	H	A	-2.1592
26	K	A	-2.8439
27	F	A	0.0000
28	S	A	-1.6626
29	V	A	0.0000
30	S	A	-0.9609
31	G	A	0.0000
32	E	A	-2.1395
33	G	A	-1.4828
34	E	A	-1.5481
35	G	A	0.0000
36	D	A	0.0545
37	A	A	0.0000
38	T	A	0.2706
39	Y	A	0.9379
40	G	A	0.0000
41	K	A	-0.3961
42	L	A	0.0000
43	T	A	-0.7597
44	L	A	0.0000
45	K	A	-0.9353
46	F	A	0.0000
47	I	A	-1.0368
48	C	A	0.0000
49	T	A	-0.7770
50	T	A	-1.2886
51	G	A	-1.5886
52	K	A	-2.2435
53	L	A	0.0000
54	P	A	-1.2001
55	V	A	0.0000
56	P	A	0.0000
57	W	A	0.0000
58	P	A	0.0000
59	T	A	0.0000
60	L	A	0.0000
61	V	A	0.0000
62	T	A	-0.0032
63	T	A	0.0000
64	F	A	0.0000
68	V	A	-0.0493
69	Q	A	-0.2122
70	C	A	0.0000
71	F	A	0.0000
72	S	A	0.0000
73	R	A	-1.1756
74	Y	A	0.0000
75	P	A	-1.7948
76	D	A	-3.0601
77	H	A	-2.2778
78	M	A	0.0000
79	K	A	-3.2977
80	R	A	-3.0432
81	H	A	-1.7551
82	D	A	0.0000
83	F	A	0.0000
84	F	A	0.0000
85	K	A	-1.1575
86	S	A	0.0000
87	A	A	0.0000
88	M	A	0.0000
89	P	A	-1.8368
90	E	A	-2.5025
91	G	A	0.0000
92	Y	A	0.0000
93	V	A	-0.9206
94	Q	A	0.0000
95	E	A	-2.5839
96	R	A	0.0000
97	T	A	-0.5137
98	I	A	0.0000
99	F	A	0.3820
100	F	A	0.0000
101	K	A	-1.5422
102	D	A	-2.5269
103	D	A	-2.4637
104	G	A	0.0000
105	N	A	-0.7187
106	Y	A	0.0000
107	K	A	-1.8639
108	T	A	0.0000
109	R	A	-3.1102
110	A	A	0.0000
111	E	A	-2.2105
112	V	A	0.0000
113	K	A	-1.9493
114	F	A	-1.9997
115	E	A	-2.7611
116	G	A	-2.2829
117	D	A	-2.5432
118	T	A	-1.7261
119	L	A	0.0000
120	V	A	0.0000
121	N	A	0.0000
122	R	A	-2.8389
123	I	A	0.0000
124	E	A	-3.9370
125	L	A	0.0000
126	K	A	-2.6728
127	G	A	0.0000
128	I	A	-1.1456
129	D	A	-2.2764
130	F	A	0.0000
131	K	A	-3.9070
132	E	A	-3.9632
133	D	A	-3.5886
134	G	A	-2.7831
135	N	A	-2.1312
136	I	A	0.0000
137	L	A	-1.9112
138	G	A	-2.2781
139	H	A	-2.2231
140	K	A	-2.5221
141	L	A	0.0000
142	E	A	-1.8579
143	Y	A	-0.6841
144	N	A	-0.6143
145	Y	A	-0.6998
146	N	A	-0.9671
147	S	A	-1.0622
148	H	A	0.0000
149	N	A	-1.0832
150	V	A	0.0000
151	Y	A	0.0708
152	I	A	0.0000
153	M	A	-0.9523
154	A	A	-1.7125
155	D	A	0.0000
156	K	A	-3.1072
157	Q	A	-3.1298
158	K	A	-3.4495
159	N	A	-2.6418
160	G	A	0.0000
161	I	A	0.0000
162	K	A	-1.5354
163	V	A	0.0000
164	N	A	-0.3741
165	F	A	0.0000
166	K	A	-1.1709
167	I	A	0.0000
168	R	A	-0.8516
169	H	A	0.0000
170	N	A	-1.1589
171	I	A	0.0000
172	E	A	-3.2768
173	D	A	-2.9819
174	G	A	-1.8037
175	S	A	-0.7053
176	V	A	0.4138
177	Q	A	0.0000
178	L	A	-0.3873
179	A	A	0.0000
180	D	A	0.0000
181	H	A	0.0000
182	Y	A	0.1672
183	Q	A	0.0000
184	Q	A	-1.7701
185	N	A	0.0000
186	T	A	-0.9746
187	P	A	-0.8383
188	I	A	-0.3974
189	G	A	-1.3280
190	D	A	-2.0285
191	G	A	-1.3737
192	P	A	-0.8354
193	V	A	-0.5723
194	L	A	-0.6519
195	L	A	-0.7839
196	P	A	0.0000
197	D	A	-2.2067
198	N	A	-1.6170
199	H	A	0.0000
200	Y	A	0.1266
201	L	A	0.0000
202	S	A	-0.6284
203	T	A	-0.8360
204	Q	A	-1.3153
205	S	A	-0.5634
206	A	A	-0.0183
207	L	A	-0.0132
208	S	A	-0.6479
209	K	A	-1.7200
210	D	A	-2.1748
211	P	A	-1.8365
212	N	A	-2.4828
213	E	A	-2.7275
214	K	A	-3.1984
215	R	A	-3.4003
216	D	A	-2.3069
217	H	A	0.0000
218	M	A	0.0000
219	V	A	-0.1259
220	L	A	0.0000
221	L	A	0.2786
222	E	A	-0.2545
223	F	A	-0.0486
224	V	A	0.0000
225	T	A	-0.4479
226	A	A	0.0000
227	A	A	0.0867
228	G	A	0.3071
229	I	A	1.2046