Project name: Tm HydA

Chain sequence(s)	B: VTLDKDRCRGCTNCIKRCPTEAIRVRDGKARIINERCIDCGECIRVCPYHAKLAVTDSLDMMKDFKYKIALPAPSLYGQFRDLTINQILSALLDVGFDEVFEVAYAAEIVSKFTREALAKGNLKKPVISSACPAVVRLVQIRFPSLIDNLLDICSPMDTAAILAKKEAIKKTGLKEEEIGVFFISPCAAKVTSVKNPIGIEKSKIDGVFSMKEIYGLIIQKAKTTVVRDLSKASMIGVGWANSGGEAFGTFTENSIYVDGIHNVVDVLEEIELGKLNDLDFFEGLACIGGCIGGPLTVENNFVAKN
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.926
• Maximal score value: 2.2745
• Average score: -0.7613
• Total score value: -232.9648

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
7	V	B	1.0537
8	T	B	0.7507
9	L	B	0.0000
10	D	B	-1.9634
11	K	B	-3.4817
12	D	B	-3.6290
13	R	B	-3.3023
14	C	B	-3.0059
15	R	B	-3.3724
16	G	B	0.0000
17	C	B	-1.7093
18	T	B	-1.9585
19	N	B	-1.3787
20	C	B	0.0000
21	I	B	-1.7077
22	K	B	-2.5899
23	R	B	-1.9631
24	C	B	-1.5699
25	P	B	-1.6619
26	T	B	-1.6853
27	E	B	-2.8870
28	A	B	0.0000
29	I	B	0.0000
30	R	B	-2.2811
31	V	B	-2.1496
32	R	B	-3.5741
33	D	B	-3.5933
34	G	B	-3.0482
35	K	B	-3.7702
36	A	B	-3.1653
37	R	B	0.0000
38	I	B	-0.2427
39	I	B	-0.8774
40	N	B	-1.9744
41	E	B	-2.7054
42	R	B	-3.0893
43	C	B	-1.6760
44	I	B	0.0000
45	D	B	-0.5918
46	C	B	0.0000
47	G	B	0.0000
48	E	B	0.0000
49	C	B	0.0000
50	I	B	0.0536
51	R	B	-0.2512
52	V	B	-0.1833
53	C	B	0.0000
54	P	B	-0.3265
55	Y	B	-0.9136
56	H	B	-1.0694
57	A	B	0.0000
58	K	B	0.0000
59	L	B	1.1392
60	A	B	1.1305
61	V	B	1.6504
62	T	B	0.1585
63	D	B	-1.5861
64	S	B	-1.4666
65	L	B	-1.7689
66	D	B	-2.6206
67	M	B	-1.5278
68	M	B	0.0000
69	K	B	-2.9173
70	D	B	-2.7782
71	F	B	-1.4441
72	K	B	-2.3460
73	Y	B	-1.7123
74	K	B	0.0000
75	I	B	0.0000
76	A	B	0.0000
77	L	B	0.0000
78	P	B	0.0000
79	A	B	0.0000
80	P	B	0.0000
81	S	B	0.0000
82	L	B	0.0000
83	Y	B	0.1108
84	G	B	0.0558
85	Q	B	-0.7383
86	F	B	0.0000
87	R	B	-1.6490
88	D	B	-1.1294
89	L	B	-0.1704
90	T	B	-0.2956
91	I	B	-0.1779
92	N	B	-1.4611
93	Q	B	-1.3366
94	I	B	0.0000
95	L	B	0.0000
96	S	B	-0.4718
97	A	B	0.0000
98	L	B	0.0000
99	L	B	-0.4219
100	D	B	-0.6015
101	V	B	-1.1832
102	G	B	-1.3378
103	F	B	0.0000
104	D	B	-2.1119
105	E	B	-1.1215
106	V	B	0.0000
107	F	B	-0.3359
108	E	B	-0.4511
109	V	B	0.0000
110	A	B	0.0000
111	Y	B	-0.3150
112	A	B	0.0000
113	A	B	0.0000
114	E	B	-0.7631
115	I	B	-0.4215
116	V	B	0.0000
117	S	B	-0.7105
118	K	B	-1.8132
119	F	B	-0.6635
120	T	B	-0.5924
121	R	B	-1.7188
122	E	B	-1.2632
123	A	B	-0.3764
124	L	B	0.5714
125	A	B	-0.2665
126	K	B	-1.0737
127	G	B	-0.9346
128	N	B	-1.5906
129	L	B	0.1526
130	K	B	-1.4967
131	K	B	-1.8706
132	P	B	0.0000
133	V	B	0.0000
134	I	B	0.0000
135	S	B	0.0000
136	S	B	0.0376
137	A	B	0.0000
138	C	B	0.0000
139	P	B	0.0000
140	A	B	0.0000
141	V	B	0.0000
142	V	B	0.1227
143	R	B	-0.9934
144	L	B	0.0000
145	V	B	0.0000
146	Q	B	-0.6740
147	I	B	-0.0685
148	R	B	-1.1444
149	F	B	0.0000
150	P	B	-0.7382
151	S	B	-0.9178
152	L	B	0.0000
153	I	B	-0.7027
154	D	B	-2.0140
155	N	B	-1.0798
156	L	B	-0.6806
157	L	B	0.0000
158	D	B	-1.6755
159	I	B	-0.2990
160	C	B	0.1709
161	S	B	0.0000
162	P	B	0.0000
163	M	B	0.0000
164	D	B	-0.1002
165	T	B	0.2604
166	A	B	0.0000
167	A	B	0.0000
168	I	B	-0.3379
169	L	B	-0.7875
170	A	B	0.0000
171	K	B	-2.8269
172	K	B	-3.1023
173	E	B	-3.1971
174	A	B	-2.3590
175	I	B	0.0000
176	K	B	-3.9418
177	K	B	-3.1736
178	T	B	-1.8738
179	G	B	-2.1092
180	L	B	-2.4909
181	K	B	-3.9159
182	E	B	-4.9260
183	E	B	-4.3584
184	E	B	-3.8309
185	I	B	0.0000
186	G	B	0.0000
187	V	B	0.0000
188	F	B	0.0000
189	F	B	0.0000
190	I	B	0.0000
191	S	B	0.0000
192	P	B	0.0000
193	C	B	0.0000
194	A	B	0.0770
195	A	B	0.0000
196	K	B	0.0000
197	V	B	-0.5724
198	T	B	-0.8832
199	S	B	-1.0354
200	V	B	-1.2834
201	K	B	-2.3173
202	N	B	-2.0169
203	P	B	-0.7313
204	I	B	0.0643
205	G	B	0.3302
206	I	B	0.6556
207	E	B	-1.8908
208	K	B	-3.0046
209	S	B	-1.9446
210	K	B	-1.3321
211	I	B	0.0000
212	D	B	-1.1815
213	G	B	0.0000
214	V	B	0.0000
215	F	B	0.0000
216	S	B	0.0000
217	M	B	0.0000
218	K	B	-0.9840
219	E	B	-0.4886
220	I	B	0.0000
221	Y	B	0.1267
222	G	B	-0.1547
223	L	B	0.0000
224	I	B	-0.0584
225	I	B	0.7417
226	Q	B	-0.6481
227	K	B	-1.1311
228	A	B	-1.0021
229	K	B	-1.8818
230	T	B	-0.5439
231	T	B	0.4956
232	V	B	1.5201
233	V	B	0.1510
234	R	B	-1.9294
235	D	B	-2.6555
236	L	B	-0.8321
237	S	B	-1.2736
238	K	B	-1.9763
239	A	B	-0.7210
240	S	B	0.2381
241	M	B	1.2609
242	I	B	1.3723
243	G	B	0.0000
244	V	B	0.6478
245	G	B	0.4148
246	W	B	0.0000
247	A	B	0.0000
248	N	B	-0.9650
249	S	B	-0.0777
250	G	B	0.4415
251	G	B	0.0000
252	E	B	0.0000
253	A	B	1.4432
254	F	B	2.2745
255	G	B	0.0000
256	T	B	0.7758
257	F	B	1.9432
258	T	B	0.1974
259	E	B	-1.8289
260	N	B	-1.6077
261	S	B	-0.3090
262	I	B	0.7336
263	Y	B	1.6973
264	V	B	0.6034
265	D	B	-0.1030
266	G	B	0.0000
267	I	B	0.0000
268	H	B	-2.0054
269	N	B	-1.5550
270	V	B	0.0000
271	V	B	-1.6624
272	D	B	-2.7331
273	V	B	0.0000
274	L	B	0.0000
275	E	B	-3.0785
276	E	B	-3.3877
277	I	B	0.0000
278	E	B	-2.5688
279	L	B	-0.9719
280	G	B	-2.0668
281	K	B	-3.1259
282	L	B	0.0000
283	N	B	-3.4944
284	D	B	-3.1518
285	L	B	0.0000
286	D	B	-2.3846
287	F	B	0.0000
288	F	B	0.0000
289	E	B	0.0000
290	G	B	0.0000
291	L	B	0.0000
292	A	B	0.0000
293	C	B	0.0000
294	I	B	0.4531
295	G	B	0.0300
296	G	B	0.0000
297	C	B	0.0000
298	I	B	0.2079
299	G	B	-0.0396
300	G	B	0.0000
301	P	B	0.0000
302	L	B	-0.0288
303	T	B	0.0000
304	V	B	-0.5882
305	E	B	-0.8625
306	N	B	-1.4256
307	N	B	-1.2814
308	F	B	0.5751
309	V	B	-0.2127
310	A	B	-1.1015
311	K	B	-2.1074
312	N	B	-1.9551