Project name: 5xhg:B

Chain sequence(s)	B: EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0164
• Maximal score value: 2.4644
• Average score: -0.5353
• Total score value: -114.5597

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.1360
2	V	B	-1.3180
3	Q	B	-1.3632
4	L	B	0.0000
5	V	B	0.3898
6	E	B	0.0000
7	S	B	-0.4529
8	G	B	-0.8625
9	G	B	-0.3051
10	G	B	0.1479
11	L	B	0.2470
12	V	B	-0.4642
13	Q	B	-1.4559
14	P	B	-1.5431
15	G	B	-1.3090
16	G	B	-1.0024
17	S	B	-1.0700
18	L	B	-1.1090
19	R	B	-2.1347
20	L	B	0.0000
21	S	B	-0.5015
22	C	B	0.0000
23	A	B	-0.2471
24	A	B	0.0000
25	S	B	-1.1800
26	G	B	-1.5435
27	F	B	-1.5702
28	N	B	-2.5088
29	I	B	0.0000
30	K	B	-2.7857
31	D	B	-3.0164
32	T	B	0.0000
33	Y	B	-0.5865
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.5313
40	A	B	-1.1081
41	P	B	-1.0464
42	G	B	-1.5819
43	K	B	-2.1031
44	G	B	-0.9771
45	L	B	0.5083
46	E	B	-0.3580
47	W	B	0.1342
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-0.7114
51	I	B	0.0000
52	Y	B	-0.3286
53	P	B	0.0000
54	T	B	-1.1092
55	N	B	-0.7942
56	G	B	-0.2557
57	Y	B	0.5469
58	T	B	-0.4914
59	R	B	-2.0424
60	Y	B	-1.8335
61	A	B	-1.7936
62	D	B	-2.6235
63	S	B	-1.7627
64	V	B	0.0000
65	K	B	-2.8677
66	G	B	-1.7657
67	R	B	-1.3959
68	F	B	0.0000
69	T	B	-1.1730
70	I	B	0.0000
71	S	B	-0.1305
72	A	B	-0.6718
73	D	B	-1.3340
74	T	B	-1.8520
75	S	B	-1.5775
76	K	B	-2.2041
77	N	B	-1.8179
78	T	B	-1.0618
79	A	B	0.0000
80	Y	B	-0.5459
81	L	B	0.0000
82	Q	B	-1.3888
83	M	B	0.0000
84	N	B	-1.2739
85	S	B	-1.1250
86	L	B	0.0000
87	R	B	-2.1345
88	A	B	-1.6296
89	E	B	-2.2096
90	D	B	0.0000
91	T	B	-0.6301
92	A	B	0.0000
93	V	B	0.4484
94	Y	B	0.0000
95	Y	B	0.3501
96	C	B	0.0000
97	S	B	0.0000
98	R	B	-0.3731
99	W	B	0.0299
100	G	B	0.0000
101	G	B	-0.5070
102	D	B	-1.4209
103	G	B	0.2616
104	F	B	1.8268
105	Y	B	1.6835
106	A	B	0.8751
107	M	B	0.4991
108	D	B	0.2196
109	Y	B	0.2877
110	W	B	0.2987
111	G	B	-0.2027
112	Q	B	-0.8325
113	G	B	-0.1158
114	T	B	0.1969
115	L	B	0.6766
116	V	B	0.0000
117	T	B	-0.2404
118	V	B	0.0000
119	S	B	-0.8517
120	S	B	-0.6390
121	A	B	-0.3954
122	S	B	-0.4988
123	T	B	-0.6997
124	K	B	-1.0852
125	G	B	-1.3641
126	P	B	0.0000
127	S	B	-0.0239
128	V	B	0.0000
129	F	B	1.0806
130	P	B	0.1825
131	L	B	0.5019
132	A	B	-0.4121
133	P	B	0.0000
134	S	B	-0.3952
141	G	B	-0.7220
142	T	B	-0.4420
143	A	B	-0.2972
144	A	B	0.0279
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.7589
149	V	B	0.0000
150	K	B	-0.1384
151	D	B	-0.5181
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.7253
156	P	B	-0.7842
157	V	B	-0.6947
158	T	B	-0.5604
159	V	B	-0.2697
160	S	B	-0.3581
161	W	B	0.0000
162	N	B	-0.7014
163	S	B	-0.6587
164	G	B	-0.5743
165	A	B	-0.2481
166	L	B	-0.0092
167	T	B	-0.3047
168	S	B	-0.3673
169	G	B	-0.5461
170	V	B	-0.0085
171	H	B	-0.4564
172	T	B	0.1348
173	F	B	0.9432
174	P	B	0.6844
175	A	B	1.2164
176	V	B	2.4644
177	L	B	2.0768
178	Q	B	0.6706
179	S	B	0.0866
180	S	B	-0.1940
181	G	B	0.2756
182	L	B	0.3515
183	Y	B	0.8253
184	S	B	0.7138
185	L	B	0.0000
186	S	B	0.6401
187	S	B	0.0000
188	V	B	0.4119
189	V	B	0.0000
190	T	B	-0.3619
191	V	B	0.0000
192	P	B	-0.5508
193	S	B	-0.5065
194	S	B	-0.5899
195	S	B	-0.6197
196	L	B	-0.8644
197	G	B	-1.0707
198	T	B	-0.9679
199	Q	B	-1.1965
200	T	B	-1.0426
201	Y	B	0.0000
202	I	B	-1.1358
203	C	B	0.0000
204	N	B	-1.4733
205	V	B	0.0000
206	N	B	-1.8473
207	H	B	0.0000
208	K	B	-2.7704
209	P	B	-1.6368
210	S	B	-1.8203
211	N	B	-2.5806
212	T	B	-2.0768
213	K	B	-2.7181
214	V	B	-1.6779
215	D	B	-2.5757
216	K	B	-2.0342
217	K	B	-2.1610
218	V	B	0.0000
219	E	B	-2.4133
220	P	B	-1.1992