Project name: 393e30d70b29895

Chain sequence(s)	A: GQPREPQVYTLPPCQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSL; B: GQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSL
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.1415
• Maximal score value: 1.5094
• Average score: -0.3447
• Total score value: -72.378

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	B	-0.6827
2	Q	B	-1.3047
3	P	B	-0.3939
4	R	B	-0.8286
5	E	B	-1.9133
6	P	B	0.0000
7	Q	B	-0.3224
8	V	B	0.0000
9	Y	B	0.0000
10	T	B	0.0000
11	L	B	0.0000
12	P	B	-0.1632
13	P	B	-0.0579
14	S	B	-0.2454
15	Q	B	-1.5327
16	E	B	-2.0374
17	E	B	0.0000
18	M	B	0.1156
19	T	B	-0.2049
20	K	B	-1.1110
21	N	B	-1.5891
22	Q	B	-1.2476
23	V	B	0.0000
24	S	B	0.0000
25	L	B	0.0000
26	T	B	0.0000
27	C	B	0.0000
28	L	B	0.0000
29	V	B	0.0000
30	K	B	-0.2232
31	G	B	-0.1247
32	F	B	0.0000
33	Y	B	0.2632
34	P	B	0.0220
35	S	B	-0.3984
36	D	B	-1.7217
37	I	B	0.1012
38	A	B	0.1425
39	V	B	0.0133
40	E	B	-0.9594
41	W	B	0.0000
42	E	B	-0.4984
43	S	B	0.0000
44	N	B	-1.3571
45	G	B	-0.9146
46	Q	B	-1.3286
47	P	B	-0.5813
48	E	B	-0.5312
49	N	B	-1.3883
50	N	B	-0.6070
51	Y	B	0.1010
52	K	B	-0.5151
53	T	B	-0.1372
54	T	B	0.0000
55	P	B	-0.1665
56	P	B	-0.0790
57	V	B	0.4784
58	L	B	1.5045
59	D	B	-0.0190
60	S	B	-0.5782
61	D	B	-1.8668
62	G	B	-0.5406
63	S	B	0.0000
64	F	B	0.4455
65	F	B	0.0000
66	L	B	0.0000
67	Y	B	0.0000
68	S	B	0.0000
69	R	B	0.0000
70	L	B	0.0000
71	T	B	0.0000
72	V	B	0.0000
73	D	B	-1.2625
74	K	B	-0.7471
75	S	B	-0.4224
76	R	B	-0.6788
77	W	B	0.0000
78	Q	B	-1.4746
79	E	B	-2.0661
80	G	B	-0.6049
81	N	B	-0.0723
82	V	B	1.2708
83	F	B	0.0000
84	S	B	-0.0499
85	C	B	0.0000
86	S	B	0.0000
87	V	B	0.0000
88	M	B	0.4492
89	H	B	0.0000
90	E	B	-1.8182
91	A	B	-0.4957
92	L	B	-0.1396
93	H	B	-1.1888
94	N	B	-1.6270
95	H	B	-1.0838
96	Y	B	0.4859
97	T	B	-0.0066
98	Q	B	-0.6528
99	K	B	-0.5349
100	S	B	-0.2392
101	L	B	0.1007
102	S	B	0.1313
103	L	B	0.1570
104	S	B	0.1073
105	L	B	1.5090
1	G	A	-0.6883
2	Q	A	-1.3054
3	P	A	-0.5287
4	R	A	-1.2892
5	E	A	-1.5296
6	P	A	0.0000
7	Q	A	-0.2786
8	V	A	0.0000
9	Y	A	0.0000
10	T	A	-0.0071
11	L	A	0.0000
12	P	A	-0.1862
13	P	A	-0.0628
14	C	A	0.0000
15	Q	A	-1.3700
16	E	A	-1.1656
17	E	A	0.0000
18	M	A	0.1599
19	T	A	-0.1861
20	K	A	-1.0475
21	N	A	-1.5310
22	Q	A	-1.0330
23	V	A	0.0000
24	S	A	0.0000
25	L	A	0.0000
26	T	A	0.0000
27	C	A	0.0000
28	L	A	0.0000
29	V	A	0.0000
30	K	A	-0.1717
31	G	A	0.0000
32	F	A	0.0000
33	Y	A	0.2708
34	P	A	0.0188
35	S	A	-0.4045
36	D	A	-1.7251
37	I	A	0.0832
38	A	A	0.1075
39	V	A	0.0000
40	E	A	-1.6144
41	W	A	0.0000
42	E	A	-0.5853
43	S	A	0.0000
44	N	A	-1.3564
45	G	A	-0.9144
46	Q	A	-1.3299
47	P	A	-0.5482
48	E	A	0.0000
49	N	A	-1.5060
50	N	A	-1.4694
51	Y	A	-0.1272
52	K	A	-0.4385
53	T	A	-0.1087
54	T	A	0.0000
55	P	A	-0.2473
56	P	A	-0.0264
57	V	A	0.6642
58	L	A	1.4026
59	D	A	0.0169
60	S	A	-0.5650
61	D	A	-1.9101
62	G	A	-0.7842
63	S	A	0.0000
64	F	A	0.4194
65	F	A	0.0000
66	L	A	0.0000
67	Y	A	0.0000
68	S	A	0.0000
69	R	A	0.0000
70	L	A	0.0000
71	T	A	-0.0079
72	V	A	0.0000
73	D	A	-1.1822
74	K	A	-0.7070
75	S	A	-0.5334
76	R	A	-0.8308
77	W	A	0.0000
78	Q	A	-1.5488
79	E	A	-2.1415
80	G	A	-0.6141
81	N	A	-0.0536
82	V	A	1.0388
83	F	A	0.0000
84	S	A	0.0000
85	C	A	0.0000
86	S	A	0.0000
87	V	A	0.0000
88	M	A	0.3803
89	H	A	0.0000
90	E	A	-1.8185
91	A	A	-0.4485
92	L	A	-0.1422
93	H	A	-1.1888
94	N	A	-1.6278
95	H	A	-1.0753
96	Y	A	0.5175
97	T	A	0.0230
98	Q	A	-0.6235
99	K	A	-0.9249
100	S	A	-0.3619
101	L	A	0.0000
102	S	A	0.1525
103	L	A	0.5005
104	S	A	0.1671
105	L	A	1.5094