Project name: 395b08f568373a0

Chain sequence(s)	A: GADYSAQWAEYYRSVGKIEEAEAIEKTLKNKQN; B: RPPPAHHNMFSVPPPPILGRG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.0061
• Maximal score value: 1.9323
• Average score: -1.3557
• Total score value: -73.2054

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
651	G	A	-2.4103
652	A	A	-1.6276
653	D	A	-2.2874
654	Y	A	-0.0629
655	S	A	0.0000
656	A	A	-1.7138
657	Q	A	-1.6774
658	W	A	-0.8122
659	A	A	0.0000
660	E	A	-2.3671
661	Y	A	-0.8287
662	Y	A	-1.7499
663	R	A	-2.5987
664	S	A	-0.7285
665	V	A	-0.0763
666	G	A	-0.9176
667	K	A	-2.0709
668	I	A	-1.8946
669	E	A	-3.1525
670	E	A	-3.5271
671	A	A	0.0000
672	E	A	-4.0061
673	A	A	-2.6842
674	I	A	0.0000
675	E	A	-3.5816
676	K	A	-3.3946
677	T	A	-2.4461
678	L	A	-2.4226
679	K	A	-3.6077
680	N	A	-3.5189
681	K	A	-3.8347
682	Q	A	-3.1778
683	N	A	-2.6861
405	R	B	-2.0704
406	P	B	-1.3275
407	P	B	-0.9986
408	P	B	-0.9799
409	A	B	-0.8366
410	H	B	-1.6697
411	H	B	-1.8004
412	N	B	-1.3427
413	M	B	0.5293
414	F	B	1.0272
415	S	B	0.9709
416	V	B	1.9323
417	P	B	0.6867
418	P	B	-0.0020
419	P	B	0.1300
420	P	B	0.4894
421	I	B	1.0392
422	L	B	0.8303
423	G	B	-0.8291
424	R	B	-1.8095
425	G	B	-1.3104