Project name: 3c08:H

Chain sequence(s)	H: QVQLVQSGAEVKKPGASVKVSCKASHWMHWVRQAPGQGLEWIGEFNPSNGRTNYNEKFKSKATMTVDTSTNTAYMELSSLRSEDTAVYYCASRDYDYDGRYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3893
• Maximal score value: 2.5584
• Average score: -0.7343
• Total score value: -159.3505

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-0.6217
2	V	H	0.5767
3	Q	H	-0.5930
4	L	H	0.0000
5	V	H	-0.3710
6	Q	H	0.0000
7	S	H	-0.7155
8	G	H	-0.9335
9	A	H	-0.8140
10	E	H	-1.2450
11	V	H	-0.9102
12	K	H	-1.7073
13	K	H	-2.4672
14	P	H	-2.1386
15	G	H	-1.5541
16	A	H	-1.2480
17	S	H	-1.3927
18	V	H	0.0000
19	K	H	-2.1363
20	V	H	0.0000
21	S	H	-0.6489
22	C	H	0.0000
23	K	H	-1.6248
24	A	H	-0.8257
25	S	H	-0.6531
32	H	H	-1.0676
33	W	H	-1.0165
34	M	H	0.0000
35	H	H	-0.4484
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.4415
40	A	H	0.0000
41	P	H	-1.1831
42	G	H	-1.3394
43	Q	H	-1.5276
44	G	H	-0.4517
45	L	H	0.8537
46	E	H	0.0000
47	W	H	0.1246
48	I	H	0.0000
49	G	H	0.0000
50	E	H	-0.9519
51	F	H	0.0000
52	N	H	-1.5940
53	P	H	-1.3916
54	S	H	-1.5470
55	N	H	-2.1306
56	G	H	-1.9980
57	R	H	-2.6181
58	T	H	-1.7164
59	N	H	-2.0328
60	Y	H	-1.8298
61	N	H	-2.1829
62	E	H	-3.3893
63	K	H	-3.1251
64	F	H	0.0000
65	K	H	-3.1153
66	S	H	-1.8454
67	K	H	-1.3973
68	A	H	0.0000
69	T	H	-0.9374
70	M	H	0.0000
71	T	H	-0.6213
72	V	H	-1.1022
73	D	H	-1.4474
74	T	H	-1.3116
75	S	H	-0.8874
76	T	H	-1.2029
77	N	H	-1.9472
78	T	H	-1.2813
79	A	H	0.0000
80	Y	H	-0.5207
81	M	H	0.0000
82	E	H	-1.6424
83	L	H	0.0000
84	S	H	-1.1248
85	S	H	-1.1538
86	L	H	0.0000
87	R	H	-2.7744
88	S	H	-2.1950
89	E	H	-2.6801
90	D	H	0.0000
91	T	H	-1.0850
92	A	H	0.0000
93	V	H	0.1845
94	Y	H	0.0000
95	Y	H	0.0301
96	C	H	0.0000
97	A	H	0.0000
98	S	H	0.0000
99	R	H	-1.6959
100	D	H	-1.3647
101	Y	H	-0.6218
102	D	H	-1.5657
103	Y	H	-0.4888
104	D	H	-2.0619
105	G	H	-1.7306
106	R	H	-1.7903
107	Y	H	-0.2060
108	F	H	-0.5574
109	D	H	-1.5066
110	Y	H	-0.7661
111	W	H	-0.3791
112	G	H	-0.4962
113	Q	H	-1.0115
114	G	H	-0.4207
115	T	H	0.0000
116	L	H	-0.1171
117	V	H	0.0000
118	T	H	0.0000
119	V	H	0.0000
120	S	H	-1.1802
121	S	H	-0.9871
122	A	H	-0.5335
123	S	H	-0.6551
124	T	H	-0.6242
125	K	H	-1.1750
126	G	H	-1.5358
127	P	H	-0.6669
128	S	H	-0.0816
129	V	H	0.0000
130	F	H	0.9920
131	P	H	0.0786
132	L	H	0.2480
133	A	H	-1.1467
134	P	H	0.0000
135	S	H	-1.5920
136	S	H	-1.4308
137	K	H	-2.0901
138	S	H	-1.0124
139	T	H	-1.0210
140	S	H	-0.9368
141	G	H	-0.8802
142	G	H	-0.9228
143	T	H	-0.6771
144	A	H	0.0000
145	A	H	-0.2113
146	L	H	0.0000
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.9643
150	V	H	0.0000
151	K	H	-0.0242
152	D	H	-0.5290
153	Y	H	0.0000
154	F	H	-0.4155
155	P	H	0.0000
156	E	H	-0.5334
157	P	H	-0.7198
158	V	H	0.0000
159	T	H	-0.7849
160	V	H	-0.5759
161	S	H	-0.4194
162	W	H	0.0000
163	N	H	-0.8399
164	S	H	-0.3780
165	G	H	-0.3945
166	A	H	-0.1225
167	L	H	0.0563
168	T	H	-0.2263
169	S	H	-0.3752
170	G	H	-0.5029
171	V	H	-0.1317
172	H	H	-0.5798
173	T	H	0.1055
174	F	H	1.0791
175	P	H	0.5954
176	A	H	1.2644
177	V	H	2.5584
178	L	H	2.1900
179	Q	H	0.6840
180	S	H	0.0911
181	S	H	-0.1797
182	G	H	0.3724
183	L	H	0.4021
184	Y	H	0.8975
185	S	H	0.0000
186	L	H	0.0000
187	S	H	0.7319
188	S	H	0.0000
189	V	H	0.3559
190	V	H	0.0000
191	T	H	-0.2986
192	V	H	0.0000
193	P	H	-0.5689
194	S	H	-0.6212
195	S	H	-0.6069
196	S	H	-0.5641
197	L	H	-0.7062
198	G	H	-0.7099
199	T	H	-0.6848
200	Q	H	-0.9360
201	T	H	-1.0867
202	Y	H	0.0000
203	I	H	-1.3438
204	C	H	0.0000
205	N	H	-1.6951
206	V	H	0.0000
207	N	H	-2.3696
208	H	H	0.0000
209	K	H	-2.7721
210	P	H	-1.7105
211	S	H	-1.8572
212	N	H	-2.4205
213	T	H	-2.1873
214	K	H	-2.9413
215	V	H	-1.8716
216	D	H	-2.6351
217	K	H	-2.2339
218	K	H	-2.4933
219	V	H	0.0000
220	E	H	-2.6986
221	P	H	-2.1473
222	K	H	-2.5139
223	S	H	-1.3822