| Chain sequence(s) |
A: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF C: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF B: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF E: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF D: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF G: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF F: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF I: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF H: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF J: VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
| Mutated residues | VA309K |
| Energy difference between WT (input) and mutated protein (by FoldX) | -0.158681 kcal/mol
Changes in protein stability upon mutation are calculated using the FoldX forcefield. Computational prediction of protein stability is used with the intention of preventing the experimental characterization of proteins bearing mutations that significantly destabilize their structure. Mutations resulting in a predicted reduction in protein stability ≥ 1 kcal/mol are considered disruptive. |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 306 | V | A | 1.9594 | |
| 307 | Q | A | -0.2558 | |
| 308 | I | A | -0.2552 | |
| 309 | K | A | -2.2770 | mutated: VA309K |
| 310 | Y | A | -1.4801 | |
| 311 | K | A | -2.1366 | |
| 312 | P | A | -0.7478 | |
| 313 | V | A | 0.8095 | |
| 314 | D | A | -0.2230 | |
| 315 | L | A | 0.8229 | |
| 316 | S | A | -0.7056 | |
| 317 | K | A | -1.5676 | |
| 318 | V | A | -1.1269 | |
| 319 | T | A | -1.3614 | |
| 320 | S | A | -1.5857 | |
| 321 | K | A | -2.4669 | |
| 322 | C | A | -1.1728 | |
| 323 | G | A | -1.0682 | |
| 324 | S | A | -0.6347 | |
| 325 | L | A | -0.0103 | |
| 326 | G | A | -0.7593 | |
| 327 | N | A | -1.5296 | |
| 328 | I | A | -0.5645 | |
| 329 | H | A | -1.1930 | |
| 330 | H | A | -0.6577 | |
| 331 | K | A | -1.3737 | |
| 332 | P | A | -0.9085 | |
| 333 | G | A | -1.0350 | |
| 334 | G | A | -0.9897 | |
| 335 | G | A | -1.0608 | |
| 336 | Q | A | -1.6851 | |
| 337 | V | A | -1.0918 | |
| 338 | E | A | -2.2889 | |
| 339 | V | A | -1.6314 | |
| 340 | K | A | -2.9809 | |
| 341 | S | A | -2.6608 | |
| 342 | E | A | -3.6299 | |
| 343 | K | A | -3.4339 | |
| 344 | L | A | -1.8829 | |
| 345 | D | A | -2.6891 | |
| 346 | F | A | -2.8272 | |
| 347 | K | A | -4.0046 | |
| 348 | D | A | -3.8771 | |
| 349 | R | A | -4.1088 | |
| 350 | V | A | -2.6662 | |
| 351 | Q | A | -2.7501 | |
| 352 | S | A | -1.6025 | |
| 353 | K | A | -2.1096 | |
| 354 | I | A | -1.0222 | |
| 355 | G | A | -1.0112 | |
| 356 | S | A | -0.8229 | |
| 357 | L | A | -0.1855 | |
| 358 | D | A | -0.2101 | |
| 359 | N | A | 0.1025 | |
| 360 | I | A | 1.2122 | |
| 361 | T | A | 0.0000 | |
| 362 | H | A | -0.5561 | |
| 363 | V | A | -0.0851 | |
| 364 | P | A | -0.4038 | |
| 365 | G | A | 0.0000 | |
| 366 | G | A | -1.2029 | |
| 367 | G | A | -1.1143 | |
| 368 | N | A | -1.6179 | |
| 369 | K | A | -2.4227 | |
| 370 | K | A | -1.5537 | |
| 371 | I | A | -0.0578 | |
| 372 | E | A | -0.6020 | |
| 373 | T | A | -0.6693 | |
| 374 | H | A | -1.1912 | |
| 375 | K | A | -2.0588 | |
| 376 | L | A | -0.3137 | |
| 377 | T | A | 0.5406 | |
| 378 | F | A | 1.8382 | |
| 306 | V | B | 1.9598 | |
| 307 | Q | B | 0.5738 | |
| 308 | I | B | 1.4577 | |
| 309 | V | B | 1.2924 | |
| 310 | Y | B | 0.3678 | |
| 311 | K | B | -1.1626 | |
| 312 | P | B | -0.2520 | |
| 313 | V | B | 0.9572 | |
| 314 | D | B | -0.0466 | |
| 315 | L | B | 0.9103 | |
| 316 | S | B | -0.6233 | |
| 317 | K | B | -1.6367 | |
| 318 | V | B | -0.9146 | |
| 319 | T | B | -1.2838 | |
| 320 | S | B | -1.4449 | |
| 321 | K | B | -2.3323 | |
| 322 | C | B | -1.0496 | |
| 323 | G | B | -0.9753 | |
| 324 | S | B | -0.5324 | |
| 325 | L | B | 0.1962 | |
| 326 | G | B | -0.6403 | |
| 327 | N | B | -1.4709 | |
| 328 | I | B | -0.6374 | |
| 329 | H | B | -1.1965 | |
| 330 | H | B | -0.7919 | |
| 331 | K | B | -1.1862 | |
| 332 | P | B | -0.9391 | |
| 333 | G | B | -0.9257 | |
| 334 | G | B | -0.7148 | |
| 335 | G | B | -0.6223 | |
| 336 | Q | B | -0.8795 | |
| 337 | V | B | -0.7703 | |
| 338 | E | B | -2.1645 | |
| 339 | V | B | -1.5479 | |
| 340 | K | B | -2.9245 | |
| 341 | S | B | -2.5725 | |
| 342 | E | B | -3.5649 | |
| 343 | K | B | -3.4995 | |
| 344 | L | B | -1.9611 | |
| 345 | D | B | -2.8335 | |
| 346 | F | B | -2.8459 | |
| 347 | K | B | -4.0008 | |
| 348 | D | B | -3.7285 | |
| 349 | R | B | -4.0087 | |
| 350 | V | B | -2.6167 | |
| 351 | Q | B | -2.7565 | |
| 352 | S | B | -1.5863 | |
| 353 | K | B | -2.1014 | |
| 354 | I | B | -0.9878 | |
| 355 | G | B | -0.9349 | |
| 356 | S | B | -0.8061 | |
| 357 | L | B | -0.0874 | |
| 358 | D | B | -0.4131 | |
| 359 | N | B | -0.0764 | |
| 360 | I | B | 1.1311 | |
| 361 | T | B | 0.0000 | |
| 362 | H | B | -0.4408 | |
| 363 | V | B | -0.0252 | |
| 364 | P | B | -0.3525 | |
| 365 | G | B | 0.0000 | |
| 366 | G | B | -1.1119 | |
| 367 | G | B | -1.0724 | |
| 368 | N | B | -1.3591 | |
| 369 | K | B | -1.9278 | |
| 370 | K | B | -0.6570 | |
| 371 | I | B | 0.4448 | |
| 372 | E | B | -0.3700 | |
| 373 | T | B | -0.6437 | |
| 374 | H | B | -1.1923 | |
| 375 | K | B | -2.1065 | |
| 376 | L | B | -0.3437 | |
| 377 | T | B | 0.5106 | |
| 378 | F | B | 1.8118 | |
| 306 | V | C | 2.5355 | |
| 307 | Q | C | 0.5624 | |
| 308 | I | C | 0.0000 | |
| 309 | V | C | -1.1982 | |
| 310 | Y | C | 0.0000 | |
| 311 | K | C | -1.8428 | |
| 312 | P | C | 0.0000 | |
| 313 | V | C | 0.3891 | |
| 314 | D | C | 0.5374 | |
| 315 | L | C | 0.7448 | |
| 316 | S | C | 0.0000 | |
| 317 | K | C | -1.1454 | |
| 318 | V | C | 0.0000 | |
| 319 | T | C | -1.6186 | |
| 320 | S | C | 0.0000 | |
| 321 | K | C | -2.9884 | |
| 322 | C | C | 0.0000 | |
| 323 | G | C | -1.2810 | |
| 324 | S | C | -0.6819 | |
| 325 | L | C | 0.0000 | |
| 326 | G | C | -0.9327 | |
| 327 | N | C | -1.5326 | |
| 328 | I | C | 0.0000 | |
| 329 | H | C | -0.9917 | |
| 330 | H | C | 0.0000 | |
| 331 | K | C | 0.0000 | |
| 332 | P | C | 0.0000 | |
| 333 | G | C | 0.0000 | |
| 334 | G | C | 0.0000 | |
| 335 | G | C | 0.0000 | |
| 336 | Q | C | 0.0000 | |
| 337 | V | C | 0.0000 | |
| 338 | E | C | -1.5663 | |
| 339 | V | C | 0.0000 | |
| 340 | K | C | -2.7181 | |
| 341 | S | C | -2.8492 | |
| 342 | E | C | -3.3952 | |
| 343 | K | C | -3.3877 | |
| 344 | L | C | 0.0000 | |
| 345 | D | C | -2.6993 | |
| 346 | F | C | 0.0000 | |
| 347 | K | C | -4.1139 | |
| 348 | D | C | -4.4682 | |
| 349 | R | C | -5.1632 | |
| 350 | V | C | 0.0000 | |
| 351 | Q | C | -2.8980 | |
| 352 | S | C | -1.5149 | |
| 353 | K | C | -1.3979 | |
| 354 | I | C | 0.0000 | |
| 355 | G | C | 0.0000 | |
| 356 | S | C | 0.0000 | |
| 357 | L | C | 0.0000 | |
| 358 | D | C | 0.0000 | |
| 359 | N | C | 0.0000 | |
| 360 | I | C | 0.5458 | |
| 361 | T | C | 0.0000 | |
| 362 | H | C | -0.3082 | |
| 363 | V | C | 0.0000 | |
| 364 | P | C | 0.0000 | |
| 365 | G | C | 0.0000 | |
| 366 | G | C | 0.0000 | |
| 367 | G | C | -1.0007 | |
| 368 | N | C | 0.0000 | |
| 369 | K | C | -1.9440 | |
| 370 | K | C | 0.0000 | |
| 371 | I | C | -0.0831 | |
| 372 | E | C | 0.0000 | |
| 373 | T | C | -0.5070 | |
| 374 | H | C | 0.0000 | |
| 375 | K | C | -1.6202 | |
| 376 | L | C | 0.0000 | |
| 377 | T | C | 0.5954 | |
| 378 | F | C | 1.9244 | |
| 306 | V | D | 2.5401 | |
| 307 | Q | D | 1.0927 | |
| 308 | I | D | 0.0000 | |
| 309 | V | D | 0.2595 | |
| 310 | Y | D | 0.0000 | |
| 311 | K | D | -0.8274 | |
| 312 | P | D | 0.0000 | |
| 313 | V | D | 0.5303 | |
| 314 | D | D | 0.0000 | |
| 315 | L | D | 0.8896 | |
| 316 | S | D | 0.0000 | |
| 317 | K | D | -1.5368 | |
| 318 | V | D | 0.0000 | |
| 319 | T | D | -1.6071 | |
| 320 | S | D | 0.0000 | |
| 321 | K | D | -2.5742 | |
| 322 | C | D | 0.0000 | |
| 323 | G | D | -1.1882 | |
| 324 | S | D | -0.5941 | |
| 325 | L | D | 0.0000 | |
| 326 | G | D | -0.8287 | |
| 327 | N | D | -1.4241 | |
| 328 | I | D | 0.0000 | |
| 329 | H | D | -0.9996 | |
| 330 | H | D | 0.0000 | |
| 331 | K | D | 0.0000 | |
| 332 | P | D | 0.0000 | |
| 333 | G | D | 0.0000 | |
| 334 | G | D | 0.0000 | |
| 335 | G | D | 0.0000 | |
| 336 | Q | D | 0.0000 | |
| 337 | V | D | 0.0000 | |
| 338 | E | D | -1.5043 | |
| 339 | V | D | 0.0000 | |
| 340 | K | D | -2.6711 | |
| 341 | S | D | 0.0000 | |
| 342 | E | D | -3.2868 | |
| 343 | K | D | -3.3975 | |
| 344 | L | D | 0.0000 | |
| 345 | D | D | -3.0935 | |
| 346 | F | D | 0.0000 | |
| 347 | K | D | -4.4085 | |
| 348 | D | D | -4.3647 | |
| 349 | R | D | -5.1355 | |
| 350 | V | D | 0.0000 | |
| 351 | Q | D | -2.9447 | |
| 352 | S | D | 0.0000 | |
| 353 | K | D | -1.3757 | |
| 354 | I | D | 0.0000 | |
| 355 | G | D | 0.0000 | |
| 356 | S | D | 0.0000 | |
| 357 | L | D | 0.0000 | |
| 358 | D | D | 0.0000 | |
| 359 | N | D | 0.0000 | |
| 360 | I | D | 0.5032 | |
| 361 | T | D | 0.0000 | |
| 362 | H | D | -0.3050 | |
| 363 | V | D | 0.0000 | |
| 364 | P | D | 0.0000 | |
| 365 | G | D | 0.0000 | |
| 366 | G | D | 0.0000 | |
| 367 | G | D | -0.9493 | |
| 368 | N | D | 0.0000 | |
| 369 | K | D | -1.5575 | |
| 370 | K | D | 0.0000 | |
| 371 | I | D | 0.1922 | |
| 372 | E | D | 0.0000 | |
| 373 | T | D | -0.5330 | |
| 374 | H | D | 0.0000 | |
| 375 | K | D | -1.7894 | |
| 376 | L | D | 0.0000 | |
| 377 | T | D | 0.5625 | |
| 378 | F | D | 1.9965 | |
| 306 | V | E | 2.6882 | |
| 307 | Q | E | 0.7538 | |
| 308 | I | E | 0.0000 | |
| 309 | V | E | -0.4796 | |
| 310 | Y | E | 0.0000 | |
| 311 | K | E | -1.5041 | |
| 312 | P | E | 0.0000 | |
| 313 | V | E | 0.5695 | |
| 314 | D | E | 0.0000 | |
| 315 | L | E | 1.1260 | |
| 316 | S | E | 0.0000 | |
| 317 | K | E | -1.3034 | |
| 318 | V | E | 0.0000 | |
| 319 | T | E | 0.0000 | |
| 320 | S | E | 0.0000 | |
| 321 | K | E | -2.6539 | |
| 322 | C | E | 0.0000 | |
| 323 | G | E | -1.3017 | |
| 324 | S | E | -0.6617 | |
| 325 | L | E | 0.0000 | |
| 326 | G | E | -1.0332 | |
| 327 | N | E | -1.5697 | |
| 328 | I | E | 0.0000 | |
| 329 | H | E | -0.7283 | |
| 330 | H | E | 0.0000 | |
| 331 | K | E | 0.0000 | |
| 332 | P | E | 0.0000 | |
| 333 | G | E | 0.0000 | |
| 334 | G | E | 0.0000 | |
| 335 | G | E | 0.0000 | |
| 336 | Q | E | 0.0000 | |
| 337 | V | E | 0.0000 | |
| 338 | E | E | -0.9801 | |
| 339 | V | E | 0.0000 | |
| 340 | K | E | -2.0116 | |
| 341 | S | E | -2.5595 | |
| 342 | E | E | -3.0906 | |
| 343 | K | E | -2.9906 | |
| 344 | L | E | 0.0000 | |
| 345 | D | E | -2.6064 | |
| 346 | F | E | 0.0000 | |
| 347 | K | E | -3.8659 | |
| 348 | D | E | -4.2932 | |
| 349 | R | E | -5.0426 | |
| 350 | V | E | 0.0000 | |
| 351 | Q | E | -2.5647 | |
| 352 | S | E | 0.0000 | |
| 353 | K | E | -1.1213 | |
| 354 | I | E | 0.0000 | |
| 355 | G | E | 0.0000 | |
| 356 | S | E | 0.0000 | |
| 357 | L | E | 0.0000 | |
| 358 | D | E | 0.0000 | |
| 359 | N | E | 0.0000 | |
| 360 | I | E | 0.5090 | |
| 361 | T | E | 0.0000 | |
| 362 | H | E | -0.4882 | |
| 363 | V | E | 0.0000 | |
| 364 | P | E | 0.0000 | |
| 365 | G | E | 0.0000 | |
| 366 | G | E | 0.0000 | |
| 367 | G | E | -0.6790 | |
| 368 | N | E | 0.0000 | |
| 369 | K | E | -1.7927 | |
| 370 | K | E | 0.0000 | |
| 371 | I | E | 0.2768 | |
| 372 | E | E | 0.0000 | |
| 373 | T | E | -0.3118 | |
| 374 | H | E | 0.0000 | |
| 375 | K | E | -1.4096 | |
| 376 | L | E | 0.0000 | |
| 377 | T | E | 0.5664 | |
| 378 | F | E | 1.7563 | |
| 306 | V | F | 2.7072 | |
| 307 | Q | F | 0.7897 | |
| 308 | I | F | 0.0000 | |
| 309 | V | F | 0.1339 | |
| 310 | Y | F | 0.0000 | |
| 311 | K | F | -1.2609 | |
| 312 | P | F | 0.0000 | |
| 313 | V | F | 0.7185 | |
| 314 | D | F | 0.0000 | |
| 315 | L | F | 1.1676 | |
| 316 | S | F | 0.0000 | |
| 317 | K | F | -1.5674 | |
| 318 | V | F | 0.0000 | |
| 319 | T | F | 0.0000 | |
| 320 | S | F | 0.0000 | |
| 321 | K | F | -2.3409 | |
| 322 | C | F | 0.0000 | |
| 323 | G | F | -1.2157 | |
| 324 | S | F | -0.6864 | |
| 325 | L | F | 0.0000 | |
| 326 | G | F | -1.0493 | |
| 327 | N | F | -1.5852 | |
| 328 | I | F | 0.0000 | |
| 329 | H | F | -0.7532 | |
| 330 | H | F | 0.0000 | |
| 331 | K | F | 0.0000 | |
| 332 | P | F | 0.0000 | |
| 333 | G | F | 0.0000 | |
| 334 | G | F | 0.0000 | |
| 335 | G | F | 0.0000 | |
| 336 | Q | F | 0.0000 | |
| 337 | V | F | 0.0000 | |
| 338 | E | F | -0.9730 | |
| 339 | V | F | 0.0000 | |
| 340 | K | F | -2.3358 | |
| 341 | S | F | -2.6704 | |
| 342 | E | F | -3.1815 | |
| 343 | K | F | -3.0040 | |
| 344 | L | F | 0.0000 | |
| 345 | D | F | -2.9380 | |
| 346 | F | F | 0.0000 | |
| 347 | K | F | -4.6002 | |
| 348 | D | F | -4.9460 | |
| 349 | R | F | -5.3476 | |
| 350 | V | F | 0.0000 | |
| 351 | Q | F | -2.5947 | |
| 352 | S | F | 0.0000 | |
| 353 | K | F | -1.0396 | |
| 354 | I | F | 0.0000 | |
| 355 | G | F | 0.0000 | |
| 356 | S | F | 0.0000 | |
| 357 | L | F | 0.0000 | |
| 358 | D | F | 0.0000 | |
| 359 | N | F | 0.0000 | |
| 360 | I | F | 0.5142 | |
| 361 | T | F | 0.0000 | |
| 362 | H | F | -0.4676 | |
| 363 | V | F | 0.0000 | |
| 364 | P | F | 0.0000 | |
| 365 | G | F | 0.0000 | |
| 366 | G | F | 0.0000 | |
| 367 | G | F | -0.6665 | |
| 368 | N | F | 0.0000 | |
| 369 | K | F | -1.7740 | |
| 370 | K | F | 0.0000 | |
| 371 | I | F | 0.3185 | |
| 372 | E | F | 0.0000 | |
| 373 | T | F | -0.3558 | |
| 374 | H | F | 0.0000 | |
| 375 | K | F | -1.6739 | |
| 376 | L | F | 0.0000 | |
| 377 | T | F | 0.5745 | |
| 378 | F | F | 1.9169 | |
| 306 | V | G | 2.6306 | |
| 307 | Q | G | 1.0064 | |
| 308 | I | G | 0.0000 | |
| 309 | V | G | -0.2600 | |
| 310 | Y | G | 0.0000 | |
| 311 | K | G | -1.4724 | |
| 312 | P | G | 0.0000 | |
| 313 | V | G | 0.2603 | |
| 314 | D | G | 0.0000 | |
| 315 | L | G | 0.6040 | |
| 316 | S | G | 0.0000 | |
| 317 | K | G | -1.1211 | |
| 318 | V | G | 0.0000 | |
| 319 | T | G | -1.3303 | |
| 320 | S | G | 0.0000 | |
| 321 | K | G | -2.6116 | |
| 322 | C | G | 0.0000 | |
| 323 | G | G | -1.1597 | |
| 324 | S | G | -0.7092 | |
| 325 | L | G | 0.0000 | |
| 326 | G | G | -1.0538 | |
| 327 | N | G | -1.4101 | |
| 328 | I | G | 0.0000 | |
| 329 | H | G | -0.8264 | |
| 330 | H | G | 0.0000 | |
| 331 | K | G | 0.0000 | |
| 332 | P | G | 0.0000 | |
| 333 | G | G | 0.0000 | |
| 334 | G | G | 0.0000 | |
| 335 | G | G | 0.0000 | |
| 336 | Q | G | 0.0000 | |
| 337 | V | G | 0.0000 | |
| 338 | E | G | -1.1347 | |
| 339 | V | G | 0.0000 | |
| 340 | K | G | -2.5472 | |
| 341 | S | G | -3.0027 | |
| 342 | E | G | -3.9043 | |
| 343 | K | G | -3.6692 | |
| 344 | L | G | 0.0000 | |
| 345 | D | G | -2.6153 | |
| 346 | F | G | 0.0000 | |
| 347 | K | G | -3.9762 | |
| 348 | D | G | -4.1762 | |
| 349 | R | G | -5.1919 | |
| 350 | V | G | 0.0000 | |
| 351 | Q | G | -2.7654 | |
| 352 | S | G | 0.0000 | |
| 353 | K | G | -1.1502 | |
| 354 | I | G | 0.0000 | |
| 355 | G | G | 0.0000 | |
| 356 | S | G | 0.0000 | |
| 357 | L | G | 0.0000 | |
| 358 | D | G | -0.6513 | |
| 359 | N | G | 0.0000 | |
| 360 | I | G | -0.1239 | |
| 361 | T | G | 0.0000 | |
| 362 | H | G | -0.4483 | |
| 363 | V | G | 0.0000 | |
| 364 | P | G | 0.0000 | |
| 365 | G | G | 0.0000 | |
| 366 | G | G | 0.0000 | |
| 367 | G | G | -0.9317 | |
| 368 | N | G | 0.0000 | |
| 369 | K | G | -2.2536 | |
| 370 | K | G | 0.0000 | |
| 371 | I | G | -0.5390 | |
| 372 | E | G | 0.0000 | |
| 373 | T | G | -0.8318 | |
| 374 | H | G | 0.0000 | |
| 375 | K | G | -1.7261 | |
| 376 | L | G | 0.0000 | |
| 377 | T | G | 0.8301 | |
| 378 | F | G | 2.1134 | |
| 306 | V | H | 2.6483 | |
| 307 | Q | H | 1.0355 | |
| 308 | I | H | 0.0000 | |
| 309 | V | H | -0.1617 | |
| 310 | Y | H | 0.0000 | |
| 311 | K | H | -0.9531 | |
| 312 | P | H | 0.0000 | |
| 313 | V | H | 0.6860 | |
| 314 | D | H | 0.0000 | |
| 315 | L | H | 0.8737 | |
| 316 | S | H | 0.0000 | |
| 317 | K | H | -1.2283 | |
| 318 | V | H | 0.0000 | |
| 319 | T | H | -1.2823 | |
| 320 | S | H | 0.0000 | |
| 321 | K | H | -2.2423 | |
| 322 | C | H | 0.0000 | |
| 323 | G | H | -1.1908 | |
| 324 | S | H | -0.7401 | |
| 325 | L | H | 0.0000 | |
| 326 | G | H | -1.1769 | |
| 327 | N | H | -1.6297 | |
| 328 | I | H | 0.0000 | |
| 329 | H | H | -1.0914 | |
| 330 | H | H | 0.0000 | |
| 331 | K | H | -1.1360 | |
| 332 | P | H | 0.0000 | |
| 333 | G | H | 0.0000 | |
| 334 | G | H | 0.0000 | |
| 335 | G | H | 0.0000 | |
| 336 | Q | H | 0.0000 | |
| 337 | V | H | 0.0000 | |
| 338 | E | H | -0.8779 | |
| 339 | V | H | 0.0000 | |
| 340 | K | H | -2.6012 | |
| 341 | S | H | 0.0000 | |
| 342 | E | H | -3.6914 | |
| 343 | K | H | -3.3998 | |
| 344 | L | H | 0.0000 | |
| 345 | D | H | -2.6214 | |
| 346 | F | H | 0.0000 | |
| 347 | K | H | -4.5735 | |
| 348 | D | H | -4.8173 | |
| 349 | R | H | -5.5252 | |
| 350 | V | H | 0.0000 | |
| 351 | Q | H | -2.7242 | |
| 352 | S | H | -1.1314 | |
| 353 | K | H | -0.8095 | |
| 354 | I | H | 0.0000 | |
| 355 | G | H | 0.0000 | |
| 356 | S | H | 0.0000 | |
| 357 | L | H | 0.0000 | |
| 358 | D | H | 0.0000 | |
| 359 | N | H | 0.0000 | |
| 360 | I | H | -0.1190 | |
| 361 | T | H | 0.0000 | |
| 362 | H | H | -0.3947 | |
| 363 | V | H | 0.0000 | |
| 364 | P | H | 0.0000 | |
| 365 | G | H | 0.0000 | |
| 366 | G | H | 0.0000 | |
| 367 | G | H | -0.9468 | |
| 368 | N | H | 0.0000 | |
| 369 | K | H | -2.2816 | |
| 370 | K | H | 0.0000 | |
| 371 | I | H | -0.5441 | |
| 372 | E | H | 0.0000 | |
| 373 | T | H | -0.6994 | |
| 374 | H | H | 0.0000 | |
| 375 | K | H | -1.8341 | |
| 376 | L | H | 0.0000 | |
| 377 | T | H | 0.8401 | |
| 378 | F | H | 2.4255 | |
| 306 | V | I | 2.0460 | |
| 307 | Q | I | 0.3505 | |
| 308 | I | I | 1.1161 | |
| 309 | V | I | -0.0660 | |
| 310 | Y | I | -0.1228 | |
| 311 | K | I | -1.6236 | |
| 312 | P | I | -0.9602 | |
| 313 | V | I | 0.3883 | |
| 314 | D | I | -0.4490 | |
| 315 | L | I | 0.6383 | |
| 316 | S | I | -0.8093 | |
| 317 | K | I | -1.5540 | |
| 318 | V | I | -1.4410 | |
| 319 | T | I | -1.2256 | |
| 320 | S | I | -1.3936 | |
| 321 | K | I | -2.0839 | |
| 322 | C | I | -1.2773 | |
| 323 | G | I | -1.1171 | |
| 324 | S | I | -0.8204 | |
| 325 | L | I | -0.4834 | |
| 326 | G | I | -1.2448 | |
| 327 | N | I | -1.6445 | |
| 328 | I | I | -0.7508 | |
| 329 | H | I | -0.9098 | |
| 330 | H | I | -0.5130 | |
| 331 | K | I | -0.8812 | |
| 332 | P | I | -0.5901 | |
| 333 | G | I | 0.0000 | |
| 334 | G | I | -0.6132 | |
| 335 | G | I | 0.0000 | |
| 336 | Q | I | -0.6847 | |
| 337 | V | I | -0.4030 | |
| 338 | E | I | -1.4540 | |
| 339 | V | I | -1.3258 | |
| 340 | K | I | -2.9271 | |
| 341 | S | I | -3.2202 | |
| 342 | E | I | -3.8446 | |
| 343 | K | I | -3.6974 | |
| 344 | L | I | -2.4908 | |
| 345 | D | I | -2.5096 | |
| 346 | F | I | -1.9693 | |
| 347 | K | I | -3.7914 | |
| 348 | D | I | -4.2913 | |
| 349 | R | I | -4.4030 | |
| 350 | V | I | -3.0383 | |
| 351 | Q | I | -2.6628 | |
| 352 | S | I | -1.4110 | |
| 353 | K | I | -1.7212 | |
| 354 | I | I | -0.1988 | |
| 355 | G | I | -0.6293 | |
| 356 | S | I | -0.7526 | |
| 357 | L | I | -0.4352 | |
| 358 | D | I | -1.6361 | |
| 359 | N | I | -1.0558 | |
| 360 | I | I | -0.1180 | |
| 361 | T | I | -0.2113 | |
| 362 | H | I | -0.8004 | |
| 363 | V | I | -0.1398 | |
| 364 | P | I | -0.4919 | |
| 365 | G | I | -0.7866 | |
| 366 | G | I | -0.8018 | |
| 367 | G | I | -1.0248 | |
| 368 | N | I | -2.0902 | |
| 369 | K | I | -2.9323 | |
| 370 | K | I | -2.7186 | |
| 371 | I | I | -1.1910 | |
| 372 | E | I | -1.3052 | |
| 373 | T | I | -1.1800 | |
| 374 | H | I | -1.9991 | |
| 375 | K | I | -2.1838 | |
| 376 | L | I | -0.0410 | |
| 377 | T | I | 0.9991 | |
| 378 | F | I | 2.5011 | |
| 306 | V | J | 2.0668 | |
| 307 | Q | J | 0.3878 | |
| 308 | I | J | 1.2563 | |
| 309 | V | J | 0.0701 | |
| 310 | Y | J | 0.0406 | |
| 311 | K | J | -1.2632 | |
| 312 | P | J | -0.4105 | |
| 313 | V | J | 1.1091 | |
| 314 | D | J | 0.2512 | |
| 315 | L | J | 1.1454 | |
| 316 | S | J | -0.5363 | |
| 317 | K | J | -1.2960 | |
| 318 | V | J | -1.3346 | |
| 319 | T | J | -1.1653 | |
| 320 | S | J | -1.3744 | |
| 321 | K | J | -2.1828 | |
| 322 | C | J | -1.3160 | |
| 323 | G | J | -1.1572 | |
| 324 | S | J | -0.9056 | |
| 325 | L | J | -0.6045 | |
| 326 | G | J | -1.3521 | |
| 327 | N | J | -1.7466 | |
| 328 | I | J | -0.8064 | |
| 329 | H | J | -1.2530 | |
| 330 | H | J | -1.1097 | |
| 331 | K | J | -2.0665 | |
| 332 | P | J | -1.2827 | |
| 333 | G | J | -0.8572 | |
| 334 | G | J | -0.9094 | |
| 335 | G | J | -0.3380 | |
| 336 | Q | J | -0.4280 | |
| 337 | V | J | -0.0025 | |
| 338 | E | J | -0.6599 | |
| 339 | V | J | -0.8778 | |
| 340 | K | J | -2.7028 | |
| 341 | S | J | -2.9772 | |
| 342 | E | J | -3.5792 | |
| 343 | K | J | -3.2160 | |
| 344 | L | J | -2.2875 | |
| 345 | D | J | -2.5253 | |
| 346 | F | J | -2.2271 | |
| 347 | K | J | -4.0393 | |
| 348 | D | J | -4.5502 | |
| 349 | R | J | -4.5954 | |
| 350 | V | J | -3.1997 | |
| 351 | Q | J | -2.5367 | |
| 352 | S | J | -1.0286 | |
| 353 | K | J | -0.8224 | |
| 354 | I | J | 0.3349 | |
| 355 | G | J | -0.0299 | |
| 356 | S | J | -0.1356 | |
| 357 | L | J | 0.0615 | |
| 358 | D | J | -1.3916 | |
| 359 | N | J | -1.1363 | |
| 360 | I | J | -0.1311 | |
| 361 | T | J | -0.2240 | |
| 362 | H | J | -0.7555 | |
| 363 | V | J | -0.0208 | |
| 364 | P | J | -0.4306 | |
| 365 | G | J | -0.8026 | |
| 366 | G | J | -0.8343 | |
| 367 | G | J | -1.0111 | |
| 368 | N | J | -2.1336 | |
| 369 | K | J | -2.9788 | |
| 370 | K | J | -2.7393 | |
| 371 | I | J | -1.1331 | |
| 372 | E | J | -1.0203 | |
| 373 | T | J | -0.8864 | |
| 374 | H | J | -1.4744 | |
| 375 | K | J | -2.1724 | |
| 376 | L | J | -0.2699 | |
| 377 | T | J | 0.8983 | |
| 378 | F | J | 2.5775 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine