Project name: 5u5m:B

Chain sequence(s)	B: EVQLVESGGGLVQPGGSLRLSSCAASGFNNIKDTYIHWVRQSPGKGLEWVARIYPTNGYTRYADSVKKGRFTISADTSKKNTAYLQMNSLRAEDTAIYYCSRWGGDGFYAMDYWGQQGTLVTVSSSASTKGPSVFPLAPSSKKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8762
• Maximal score value: 2.4815
• Average score: -0.5629
• Total score value: -125.5207

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.0169
2	V	B	-1.1504
3	Q	B	-0.8214
4	L	B	0.0000
5	V	B	0.5957
6	E	B	0.0000
7	S	B	-0.4960
8	G	B	-0.8918
9	G	B	-0.3949
10	G	B	-0.4757
11	L	B	-0.1196
12	V	B	0.0000
13	Q	B	-1.6357
14	P	B	-1.6758
15	G	B	-1.4176
16	G	B	-1.1319
17	S	B	-1.1463
18	L	B	-1.1194
19	R	B	-1.9789
20	L	B	0.0000
21	S	B	-0.4139
22	C	B	0.0000
23	A	B	-0.1693
24	A	B	0.0000
25	S	B	-1.0136
26	G	B	-1.3124
27	F	B	-1.4928
28	N	B	-2.1032
29	I	B	0.0000
30	K	B	-2.5104
31	D	B	-2.7834
32	T	B	0.0000
33	Y	B	0.1194
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.3207
40	S	B	-0.9945
41	P	B	-1.0914
42	G	B	-1.7207
43	K	B	-2.1918
44	G	B	-0.7171
45	L	B	0.6149
46	E	B	-0.1594
47	W	B	0.2628
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-0.9627
51	I	B	0.0000
52	Y	B	-0.3942
53	P	B	-1.0100
54	T	B	-1.0571
55	N	B	-0.7850
56	G	B	-0.3313
57	Y	B	0.4560
58	T	B	-0.6054
59	R	B	-2.1431
60	Y	B	-1.9051
61	A	B	-1.7903
62	D	B	-2.6735
63	S	B	-1.8280
64	V	B	0.0000
65	K	B	-2.8762
66	G	B	-1.7900
67	R	B	-1.4112
68	F	B	0.0000
69	T	B	-1.1276
70	I	B	0.0000
71	S	B	-0.1684
72	A	B	-0.7220
73	D	B	-1.3205
74	T	B	-1.5038
75	S	B	-1.5121
76	K	B	-2.1864
77	N	B	-1.7073
78	T	B	-0.8666
79	A	B	0.0000
80	Y	B	-0.4211
81	L	B	0.0000
82	Q	B	-1.0962
83	M	B	0.0000
84	N	B	-1.4115
85	S	B	-1.2549
86	L	B	0.0000
87	R	B	-2.2693
88	A	B	-1.7035
89	E	B	-2.5827
90	D	B	0.0000
91	T	B	-0.7797
92	A	B	0.0000
93	I	B	0.6327
94	Y	B	0.0000
95	Y	B	0.2647
96	C	B	0.0000
97	S	B	0.0000
98	R	B	0.0000
99	W	B	0.6832
100	G	B	0.4085
101	G	B	0.0000
102	D	B	-1.5163
103	G	B	-0.2126
104	F	B	1.7514
105	Y	B	1.9504
106	A	B	1.2949
107	M	B	0.9764
108	D	B	0.3502
109	Y	B	0.4458
110	W	B	0.5056
111	G	B	-0.0289
112	Q	B	-0.7592
113	G	B	-0.1354
114	T	B	0.0644
115	L	B	0.2552
116	V	B	0.0000
117	T	B	-0.3811
118	V	B	0.0000
119	S	B	-0.7731
120	S	B	-0.7158
121	A	B	-0.4683
122	S	B	-0.5751
123	T	B	-0.6553
124	K	B	-1.2888
125	G	B	-1.5734
126	P	B	0.0000
127	S	B	-0.1375
128	V	B	0.0000
129	F	B	1.0674
130	P	B	0.1857
131	L	B	0.3601
132	A	B	-1.0652
133	P	B	0.0000
134	S	B	-1.3143
135	S	B	-1.1504
136	K	B	-1.8947
137	S	B	-0.9968
138	T	B	-0.9904
139	S	B	-0.9444
140	G	B	-0.8562
141	G	B	-0.9169
142	T	B	-0.6362
143	A	B	0.0000
144	A	B	-0.1980
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.7609
149	V	B	0.0000
150	K	B	-0.3060
151	D	B	-0.5399
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.5692
156	P	B	-0.7167
157	V	B	-0.6911
158	T	B	-0.5981
159	V	B	-0.1943
160	S	B	-0.3972
161	W	B	0.0000
162	N	B	-0.8016
163	S	B	-0.6720
164	G	B	-0.5714
165	A	B	-0.2509
166	L	B	-0.0444
167	T	B	-0.2964
168	S	B	-0.3626
169	G	B	-0.4566
170	V	B	0.0303
171	H	B	-0.3822
172	T	B	0.1962
173	F	B	1.0077
174	P	B	0.7494
175	A	B	1.2975
176	V	B	2.4815
177	L	B	2.2024
178	Q	B	0.7041
179	S	B	0.0968
180	S	B	-0.2342
181	G	B	0.1824
182	L	B	0.2271
183	Y	B	0.8428
184	S	B	0.0000
185	L	B	0.0000
186	S	B	0.7033
187	S	B	0.0000
188	V	B	0.4573
189	V	B	0.0000
190	T	B	-0.2273
191	V	B	0.0000
192	P	B	-0.6172
193	S	B	-0.5461
194	S	B	-0.5214
195	S	B	-0.4903
196	L	B	-0.6736
197	G	B	-1.0289
198	T	B	-0.6669
199	Q	B	-1.1809
200	T	B	-1.1169
201	Y	B	0.0000
202	I	B	-1.4098
203	C	B	0.0000
204	N	B	-1.5477
205	V	B	0.0000
206	N	B	-2.1366
207	H	B	0.0000
208	K	B	-2.8532
209	P	B	-1.6442
210	S	B	-1.8920
211	N	B	-2.6466
212	T	B	-2.1770
213	K	B	-2.8330
214	V	B	-1.8071
215	D	B	-2.5744
216	K	B	-2.1277
217	K	B	-2.5017
218	V	B	0.0000
219	E	B	-2.8469
220	P	B	-1.8338
221	K	B	-2.1114
222	S	B	-0.9495
223	C	B	0.1890