Project name: 3u0t:A

Chain sequence(s)	A: VVMTQSPLSLPVTLGQPASISCKSSQSLLYSDAKTYLNWFQQRPGQSPRRLIYQISRLDPGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCLQGTHYPVLFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6263
• Maximal score value: 2.5648
• Average score: -0.703
• Total score value: -153.2463

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	A	1.4358
3	V	A	1.7535
4	M	A	0.0000
5	T	A	-0.2955
6	Q	A	0.0000
7	S	A	-0.2547
8	P	A	0.2176
9	L	A	0.9056
10	S	A	0.1612
11	L	A	-0.1185
12	P	A	-0.7106
13	V	A	0.0000
14	T	A	-1.1449
15	L	A	-0.7792
16	G	A	-1.4641
17	Q	A	-1.8249
18	P	A	-1.8748
19	A	A	-1.0873
20	S	A	-0.6574
21	I	A	0.0000
22	S	A	-0.7639
23	C	A	0.0000
24	K	A	-2.0740
25	S	A	-0.8469
26	S	A	-0.3938
27	Q	A	-0.6956
27A	S	A	-0.2449
27B	L	A	0.0000
27C	L	A	1.4029
27D	Y	A	1.0860
27E	S	A	-0.2634
28	D	A	-1.4724
29	A	A	-0.6335
30	K	A	-0.6392
31	T	A	0.0000
32	Y	A	0.4706
33	L	A	0.0000
34	N	A	-0.0347
35	W	A	0.0000
36	F	A	-0.0429
37	Q	A	0.0000
38	Q	A	-1.2389
39	R	A	-1.5546
40	P	A	-1.3767
41	G	A	-1.4637
42	Q	A	-1.7026
43	S	A	-1.2684
44	P	A	-1.2702
45	R	A	-1.4277
46	R	A	-0.9898
47	L	A	0.0000
48	I	A	0.0000
49	Y	A	-0.4301
50	Q	A	-0.7041
51	I	A	-0.6759
52	S	A	-1.0195
53	R	A	-1.6869
54	L	A	-0.8769
55	D	A	-0.7395
56	P	A	-0.6716
57	G	A	-0.7568
58	V	A	-0.7374
59	P	A	-1.0760
60	D	A	-1.9739
61	R	A	-2.1420
62	F	A	0.0000
63	S	A	-1.2090
64	G	A	-0.7783
65	S	A	-0.8982
66	G	A	-1.0191
67	S	A	-0.7167
68	G	A	-0.3480
69	T	A	-1.3654
70	D	A	-2.2325
71	F	A	0.0000
72	T	A	-0.9623
73	L	A	0.0000
74	K	A	-1.4698
75	I	A	0.0000
76	S	A	-2.2414
77	R	A	-2.8723
78	V	A	0.0000
79	E	A	-2.6143
80	A	A	-1.7841
81	E	A	-2.3505
82	D	A	0.0000
83	V	A	-1.1666
84	G	A	-1.0562
85	V	A	-0.2584
86	Y	A	0.0000
87	Y	A	0.2932
88	C	A	0.0000
89	L	A	1.1303
90	Q	A	0.0000
91	G	A	0.9358
92	T	A	1.0135
93	H	A	1.0798
94	Y	A	1.7321
95	P	A	1.9165
96	V	A	2.5648
97	L	A	2.3862
98	F	A	2.0238
99	G	A	0.0000
100	Q	A	-0.5598
101	G	A	0.0000
102	T	A	0.0000
103	R	A	-0.7894
104	L	A	0.0000
105	E	A	0.0000
106	I	A	0.0000
107	K	A	-1.5459
108	R	A	-1.2096
109	T	A	-0.3529
110	V	A	-0.0115
111	A	A	-0.1397
112	A	A	-0.2611
113	P	A	0.0000
114	S	A	-0.1565
115	V	A	0.0000
116	F	A	1.1149
117	I	A	1.1304
118	F	A	1.3741
119	P	A	0.3126
120	P	A	-0.7039
121	S	A	-1.8365
122	D	A	-3.2501
123	E	A	-3.4837
124	Q	A	-2.5230
125	L	A	-2.6832
126	K	A	-3.1330
127	S	A	-1.9973
128	G	A	-1.4106
129	T	A	-1.2136
130	A	A	0.0000
131	S	A	-0.0056
132	V	A	0.0000
133	V	A	0.6179
134	C	A	0.0000
135	L	A	0.5239
136	L	A	0.0000
137	N	A	-0.6387
138	N	A	-1.3206
139	F	A	0.0000
140	Y	A	0.0000
141	P	A	-1.6868
142	R	A	-2.4896
143	E	A	-2.9747
144	A	A	-2.2384
145	K	A	-2.2495
146	V	A	-1.0729
147	Q	A	-0.5027
148	W	A	0.0000
149	K	A	-0.4378
150	V	A	0.0000
151	D	A	-1.6974
152	N	A	-1.3816
153	A	A	-0.2621
154	L	A	0.7576
155	Q	A	-0.0456
156	S	A	-0.5028
157	G	A	-0.9810
158	N	A	-0.9366
159	S	A	-1.4054
160	Q	A	-2.3294
161	E	A	-2.3926
162	S	A	-1.2359
163	V	A	-1.0045
164	T	A	-1.2172
165	E	A	-2.1926
166	Q	A	-1.8828
167	D	A	-1.9627
168	S	A	-2.1461
169	K	A	-2.3377
170	D	A	-2.0240
171	S	A	-1.8590
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-0.9443
175	L	A	0.0000
176	S	A	-0.5392
177	S	A	0.0000
178	T	A	-0.6520
179	L	A	0.0000
180	T	A	-0.3986
181	L	A	-0.7292
182	S	A	-1.1670
183	K	A	-2.2906
184	A	A	-2.0171
185	D	A	-2.6628
186	Y	A	0.0000
187	E	A	-3.5522
188	K	A	-3.6263
189	H	A	-2.8467
190	K	A	-2.6091
191	V	A	-0.8398
192	Y	A	0.0000
193	A	A	-0.4034
194	C	A	0.0000
195	E	A	-0.6575
196	V	A	0.0000
197	T	A	-1.1512
198	H	A	0.0000
199	Q	A	-1.7575
200	G	A	-0.5218
201	L	A	-0.2157
202	S	A	-0.4123
203	S	A	-0.3950
204	P	A	-0.4529
205	V	A	0.1369
206	T	A	-0.3169
207	K	A	-0.3959
208	S	A	-0.2294
209	F	A	-0.3789
210	N	A	-1.3310
211	R	A	-1.8683
212	G	A	-1.7564
213	E	A	-2.0216
214	C	A	-0.4642