Project name: 1yy9:C
Status: done
submitted: 2019-03-20 20:06:14, status changed: 2019-03-20 20:19:02
Settings
|
Chain sequence(s)
|
C: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7647
-
Maximal score value
-
1.8362
-
Average score
-
-0.8868
-
Total score value
-
-187.1205
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
C |
-1.5376 |
|
| 2 |
I |
C |
0.0000 |
|
| 3 |
L |
C |
0.6748 |
|
| 4 |
L |
C |
0.0000 |
|
| 5 |
T |
C |
-0.1211 |
|
| 6 |
Q |
C |
-0.0769 |
|
| 7 |
S |
C |
0.0491 |
|
| 8 |
P |
C |
0.7969 |
|
| 9 |
V |
C |
1.8362 |
|
| 10 |
I |
C |
1.3667 |
|
| 11 |
L |
C |
0.5219 |
|
| 12 |
S |
C |
-0.1185 |
|
| 13 |
V |
C |
-0.8711 |
|
| 14 |
S |
C |
-1.5322 |
|
| 15 |
P |
C |
-1.9373 |
|
| 16 |
G |
C |
-2.1340 |
|
| 17 |
E |
C |
-2.9374 |
|
| 18 |
R |
C |
-3.2747 |
|
| 19 |
V |
C |
0.0000 |
|
| 20 |
S |
C |
-0.9030 |
|
| 21 |
F |
C |
0.0000 |
|
| 22 |
S |
C |
-0.9610 |
|
| 23 |
C |
C |
0.0000 |
|
| 24 |
R |
C |
-2.3648 |
|
| 25 |
A |
C |
0.0000 |
|
| 26 |
S |
C |
-1.1292 |
|
| 27 |
Q |
C |
-1.9479 |
|
| 28 |
S |
C |
-1.5652 |
|
| 29 |
I |
C |
0.0000 |
|
| 30 |
G |
C |
-1.1097 |
|
| 31 |
T |
C |
-1.0701 |
|
| 32 |
N |
C |
-1.1600 |
|
| 33 |
I |
C |
0.0000 |
|
| 34 |
H |
C |
0.0000 |
|
| 35 |
W |
C |
0.0000 |
|
| 36 |
Y |
C |
-0.0808 |
|
| 37 |
Q |
C |
0.0000 |
|
| 38 |
Q |
C |
-1.3711 |
|
| 39 |
R |
C |
-1.9621 |
|
| 40 |
T |
C |
-1.6405 |
|
| 41 |
N |
C |
-1.7467 |
|
| 42 |
G |
C |
-1.4550 |
|
| 43 |
S |
C |
-1.0514 |
|
| 44 |
P |
C |
-0.9258 |
|
| 45 |
R |
C |
-0.6687 |
|
| 46 |
L |
C |
-0.0701 |
|
| 47 |
L |
C |
0.0000 |
|
| 48 |
I |
C |
0.0000 |
|
| 49 |
K |
C |
-1.3065 |
|
| 50 |
Y |
C |
-0.8347 |
|
| 51 |
A |
C |
0.0000 |
|
| 52 |
S |
C |
-1.3740 |
|
| 53 |
E |
C |
-2.1744 |
|
| 54 |
S |
C |
-1.2485 |
|
| 55 |
I |
C |
-0.5857 |
|
| 56 |
S |
C |
-0.4620 |
|
| 57 |
G |
C |
-0.4062 |
|
| 58 |
I |
C |
-0.2146 |
|
| 59 |
P |
C |
-0.4504 |
|
| 60 |
S |
C |
-0.8017 |
|
| 61 |
R |
C |
-1.6102 |
|
| 62 |
F |
C |
0.0000 |
|
| 63 |
S |
C |
-1.0233 |
|
| 64 |
G |
C |
-0.8231 |
|
| 65 |
S |
C |
-0.8101 |
|
| 66 |
G |
C |
-0.9923 |
|
| 67 |
S |
C |
-0.8581 |
|
| 68 |
G |
C |
-1.3220 |
|
| 69 |
T |
C |
-1.8062 |
|
| 70 |
D |
C |
-2.2341 |
|
| 71 |
F |
C |
0.0000 |
|
| 72 |
T |
C |
-0.8214 |
|
| 73 |
L |
C |
0.0000 |
|
| 74 |
S |
C |
-1.0294 |
|
| 75 |
I |
C |
0.0000 |
|
| 76 |
N |
C |
-3.0771 |
|
| 77 |
S |
C |
-2.5244 |
|
| 78 |
V |
C |
0.0000 |
|
| 79 |
E |
C |
-2.5480 |
|
| 80 |
S |
C |
-2.2871 |
|
| 81 |
E |
C |
-2.6982 |
|
| 82 |
D |
C |
0.0000 |
|
| 83 |
I |
C |
-1.6093 |
|
| 84 |
A |
C |
0.0000 |
|
| 85 |
D |
C |
-0.6880 |
|
| 86 |
Y |
C |
0.0000 |
|
| 87 |
Y |
C |
0.1286 |
|
| 88 |
C |
C |
0.0000 |
|
| 89 |
Q |
C |
0.1007 |
|
| 90 |
Q |
C |
0.0000 |
|
| 91 |
N |
C |
-1.3040 |
|
| 92 |
N |
C |
-1.7963 |
|
| 93 |
N |
C |
-1.1646 |
|
| 94 |
W |
C |
0.2202 |
|
| 95 |
P |
C |
-0.0115 |
|
| 96 |
T |
C |
-0.1173 |
|
| 97 |
T |
C |
0.3941 |
|
| 98 |
F |
C |
1.3516 |
|
| 99 |
G |
C |
0.5601 |
|
| 100 |
A |
C |
0.3716 |
|
| 101 |
G |
C |
0.2480 |
|
| 102 |
T |
C |
0.0000 |
|
| 103 |
K |
C |
-0.5689 |
|
| 104 |
L |
C |
0.0000 |
|
| 105 |
E |
C |
-0.7450 |
|
| 106 |
L |
C |
0.0000 |
|
| 107 |
K |
C |
-1.1999 |
|
| 108 |
R |
C |
-1.0271 |
|
| 109 |
T |
C |
-0.1465 |
|
| 110 |
V |
C |
0.1920 |
|
| 111 |
A |
C |
-0.2434 |
|
| 112 |
A |
C |
-0.2273 |
|
| 113 |
P |
C |
0.0000 |
|
| 114 |
S |
C |
-0.1800 |
|
| 115 |
V |
C |
0.0000 |
|
| 116 |
F |
C |
0.9902 |
|
| 117 |
I |
C |
1.0107 |
|
| 118 |
F |
C |
1.2730 |
|
| 119 |
P |
C |
-0.0333 |
|
| 120 |
P |
C |
0.0000 |
|
| 121 |
S |
C |
-1.5139 |
|
| 122 |
D |
C |
-3.1772 |
|
| 123 |
E |
C |
-3.5591 |
|
| 124 |
Q |
C |
-2.5868 |
|
| 125 |
L |
C |
-2.6534 |
|
| 126 |
K |
C |
-3.1056 |
|
| 127 |
S |
C |
-2.1643 |
|
| 128 |
G |
C |
-1.6176 |
|
| 129 |
T |
C |
-1.3621 |
|
| 130 |
A |
C |
0.0000 |
|
| 131 |
S |
C |
-0.0662 |
|
| 132 |
V |
C |
0.0000 |
|
| 133 |
V |
C |
0.6328 |
|
| 134 |
C |
C |
0.0000 |
|
| 135 |
L |
C |
0.5007 |
|
| 136 |
L |
C |
0.0000 |
|
| 137 |
N |
C |
-0.6402 |
|
| 138 |
N |
C |
-1.2471 |
|
| 139 |
F |
C |
0.0000 |
|
| 140 |
Y |
C |
0.0000 |
|
| 141 |
P |
C |
-1.7361 |
|
| 142 |
R |
C |
-3.0279 |
|
| 143 |
E |
C |
-3.2312 |
|
| 144 |
A |
C |
-2.3045 |
|
| 145 |
K |
C |
-2.4358 |
|
| 146 |
V |
C |
-1.0856 |
|
| 147 |
Q |
C |
-0.7316 |
|
| 148 |
W |
C |
0.0000 |
|
| 149 |
K |
C |
-1.0643 |
|
| 150 |
V |
C |
0.0000 |
|
| 151 |
D |
C |
-2.3635 |
|
| 152 |
N |
C |
-1.6944 |
|
| 153 |
A |
C |
-0.6442 |
|
| 154 |
L |
C |
0.0757 |
|
| 155 |
Q |
C |
-0.5096 |
|
| 156 |
S |
C |
-0.8120 |
|
| 157 |
G |
C |
-1.1970 |
|
| 158 |
N |
C |
-1.3330 |
|
| 159 |
S |
C |
-1.6412 |
|
| 160 |
Q |
C |
-2.4187 |
|
| 161 |
E |
C |
-2.3560 |
|
| 162 |
S |
C |
-1.3655 |
|
| 163 |
V |
C |
-0.8114 |
|
| 164 |
T |
C |
-1.2860 |
|
| 165 |
E |
C |
-2.3284 |
|
| 166 |
Q |
C |
-2.1408 |
|
| 167 |
D |
C |
-2.6594 |
|
| 168 |
S |
C |
-2.5321 |
|
| 169 |
K |
C |
-2.6041 |
|
| 170 |
D |
C |
-1.8163 |
|
| 171 |
S |
C |
0.0000 |
|
| 172 |
T |
C |
0.0000 |
|
| 173 |
Y |
C |
0.0000 |
|
| 174 |
S |
C |
-1.0365 |
|
| 175 |
L |
C |
0.0000 |
|
| 176 |
S |
C |
-0.4960 |
|
| 177 |
S |
C |
0.0000 |
|
| 178 |
T |
C |
-0.7188 |
|
| 179 |
L |
C |
0.0000 |
|
| 180 |
T |
C |
-0.6450 |
|
| 181 |
L |
C |
-0.6222 |
|
| 182 |
S |
C |
-1.4360 |
|
| 183 |
K |
C |
-2.6241 |
|
| 184 |
A |
C |
-2.5559 |
|
| 185 |
D |
C |
-2.6702 |
|
| 186 |
Y |
C |
0.0000 |
|
| 187 |
E |
C |
-3.7647 |
|
| 188 |
K |
C |
-3.7395 |
|
| 189 |
H |
C |
-3.3809 |
|
| 190 |
K |
C |
-3.6207 |
|
| 191 |
V |
C |
-2.3746 |
|
| 192 |
Y |
C |
0.0000 |
|
| 193 |
A |
C |
0.0000 |
|
| 194 |
C |
C |
0.0000 |
|
| 195 |
E |
C |
-0.7358 |
|
| 196 |
V |
C |
0.0000 |
|
| 197 |
T |
C |
-1.2093 |
|
| 198 |
H |
C |
0.0000 |
|
| 199 |
Q |
C |
-1.7822 |
|
| 200 |
G |
C |
-0.4869 |
|
| 201 |
L |
C |
-0.2240 |
|
| 202 |
S |
C |
-0.4545 |
|
| 203 |
S |
C |
-0.4089 |
|
| 204 |
P |
C |
-0.4781 |
|
| 205 |
V |
C |
0.0133 |
|
| 206 |
T |
C |
-0.4030 |
|
| 207 |
K |
C |
-0.4224 |
|
| 208 |
S |
C |
-0.6953 |
|
| 209 |
F |
C |
-1.1420 |
|
| 210 |
N |
C |
-2.5072 |
|
| 211 |
R |
C |
-2.8606 |
|