Project name: 5sx4:L
Status: done
submitted: 2019-03-20 20:34:09, status changed: 2019-03-20 20:43:47
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYFCQHFDHLPLAFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8956
-
Maximal score value
-
1.9949
-
Average score
-
-0.8239
-
Total score value
-
-175.4874
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.8832 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.8165 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.8592 |
|
| 6 |
Q |
L |
-0.6309 |
|
| 7 |
S |
L |
-0.5440 |
|
| 8 |
P |
L |
-0.6581 |
|
| 9 |
S |
L |
-0.8959 |
|
| 10 |
S |
L |
-1.0339 |
|
| 11 |
L |
L |
-0.6567 |
|
| 12 |
S |
L |
-0.9205 |
|
| 13 |
A |
L |
-1.0564 |
|
| 14 |
S |
L |
-0.9667 |
|
| 15 |
V |
L |
-0.0763 |
|
| 16 |
G |
L |
-0.8358 |
|
| 17 |
D |
L |
-1.9586 |
|
| 18 |
R |
L |
-2.3899 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6675 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7454 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
Q |
L |
-1.9929 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-1.9678 |
|
| 27 |
Q |
L |
-2.4543 |
|
| 28 |
D |
L |
-2.6403 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
S |
L |
-1.2193 |
|
| 31 |
N |
L |
-0.9738 |
|
| 32 |
Y |
L |
-0.0931 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
N |
L |
0.2527 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.0849 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5500 |
|
| 39 |
K |
L |
-2.0657 |
|
| 40 |
P |
L |
-1.6918 |
|
| 41 |
G |
L |
-1.7391 |
|
| 42 |
K |
L |
-2.3581 |
|
| 43 |
A |
L |
-1.3796 |
|
| 44 |
P |
L |
-1.2207 |
|
| 45 |
K |
L |
-1.3836 |
|
| 46 |
L |
L |
-0.0621 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.1821 |
|
| 50 |
D |
L |
-0.8657 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.9761 |
|
| 53 |
N |
L |
-1.1705 |
|
| 54 |
L |
L |
-0.2555 |
|
| 55 |
E |
L |
-0.5725 |
|
| 56 |
T |
L |
-0.4594 |
|
| 57 |
G |
L |
-0.5062 |
|
| 58 |
V |
L |
-0.3140 |
|
| 59 |
P |
L |
-0.3832 |
|
| 60 |
S |
L |
-0.4851 |
|
| 61 |
R |
L |
-0.8521 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.5246 |
|
| 64 |
G |
L |
-0.5206 |
|
| 65 |
S |
L |
-1.0267 |
|
| 66 |
G |
L |
-1.1529 |
|
| 67 |
S |
L |
-1.3170 |
|
| 68 |
G |
L |
-1.7052 |
|
| 69 |
T |
L |
-2.1481 |
|
| 70 |
D |
L |
-2.6092 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7536 |
|
| 73 |
F |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6243 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3685 |
|
| 77 |
S |
L |
-1.1638 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.9822 |
|
| 80 |
P |
L |
-1.6835 |
|
| 81 |
E |
L |
-2.1590 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
I |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-1.1054 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
F |
L |
0.1157 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
H |
L |
0.0000 |
|
| 91 |
F |
L |
1.0849 |
|
| 92 |
D |
L |
-0.2079 |
|
| 93 |
H |
L |
0.2830 |
|
| 94 |
L |
L |
1.3996 |
|
| 95 |
P |
L |
1.0287 |
|
| 96 |
L |
L |
1.9949 |
|
| 97 |
A |
L |
1.1229 |
|
| 98 |
F |
L |
1.5858 |
|
| 99 |
G |
L |
0.1361 |
|
| 100 |
G |
L |
-0.5390 |
|
| 101 |
G |
L |
-0.5195 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-2.0295 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.5842 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.5453 |
|
| 108 |
R |
L |
-1.1048 |
|
| 109 |
T |
L |
-0.3033 |
|
| 110 |
V |
L |
0.0822 |
|
| 111 |
A |
L |
-0.1771 |
|
| 112 |
A |
L |
-0.2711 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1118 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.2516 |
|
| 117 |
I |
L |
1.1797 |
|
| 118 |
F |
L |
1.3059 |
|
| 119 |
P |
L |
-0.0243 |
|
| 120 |
P |
L |
-0.7135 |
|
| 121 |
S |
L |
-1.8476 |
|
| 122 |
D |
L |
-3.2535 |
|
| 123 |
E |
L |
-3.4220 |
|
| 124 |
Q |
L |
-2.5718 |
|
| 125 |
L |
L |
-2.5941 |
|
| 126 |
K |
L |
-2.9985 |
|
| 127 |
S |
L |
-1.8969 |
|
| 128 |
G |
L |
-1.3282 |
|
| 129 |
T |
L |
-0.9999 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0012 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.6379 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5047 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6272 |
|
| 138 |
N |
L |
-1.3035 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
-1.2262 |
|
| 141 |
P |
L |
-1.7021 |
|
| 142 |
R |
L |
-2.7999 |
|
| 143 |
E |
L |
-3.0817 |
|
| 144 |
A |
L |
-2.2488 |
|
| 145 |
K |
L |
-2.2681 |
|
| 146 |
V |
L |
-1.0469 |
|
| 147 |
Q |
L |
-0.5951 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5348 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.8071 |
|
| 152 |
N |
L |
-1.3853 |
|
| 153 |
A |
L |
-0.2845 |
|
| 154 |
L |
L |
0.7250 |
|
| 155 |
Q |
L |
-0.1041 |
|
| 156 |
S |
L |
-0.5636 |
|
| 157 |
G |
L |
-1.0347 |
|
| 158 |
N |
L |
-1.0163 |
|
| 159 |
S |
L |
-1.4557 |
|
| 160 |
Q |
L |
-2.3388 |
|
| 161 |
E |
L |
-2.3210 |
|
| 162 |
S |
L |
-1.2986 |
|
| 163 |
V |
L |
-0.7317 |
|
| 164 |
T |
L |
-1.1958 |
|
| 165 |
E |
L |
-2.3498 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.3836 |
|
| 168 |
S |
L |
-2.4329 |
|
| 169 |
K |
L |
-2.6152 |
|
| 170 |
D |
L |
-1.8440 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9837 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4127 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6441 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.4089 |
|
| 181 |
L |
L |
-0.7620 |
|
| 182 |
S |
L |
-1.1876 |
|
| 183 |
K |
L |
-2.2305 |
|
| 184 |
A |
L |
-2.0622 |
|
| 185 |
D |
L |
-2.8776 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.8956 |
|
| 188 |
K |
L |
-3.7907 |
|
| 189 |
H |
L |
-3.1690 |
|
| 190 |
K |
L |
-3.1426 |
|
| 191 |
V |
L |
-1.2084 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
-0.7582 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.9416 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.1820 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.5564 |
|
| 200 |
G |
L |
-0.4886 |
|
| 201 |
L |
L |
-0.2689 |
|
| 202 |
S |
L |
-0.4610 |
|
| 203 |
S |
L |
-0.3921 |
|
| 204 |
P |
L |
-0.5382 |
|
| 205 |
V |
L |
0.0708 |
|
| 206 |
T |
L |
-0.3851 |
|
| 207 |
K |
L |
-0.4046 |
|
| 208 |
S |
L |
-0.2792 |
|
| 209 |
F |
L |
-0.6984 |
|
| 210 |
N |
L |
-1.8005 |
|
| 211 |
R |
L |
-2.7448 |
|
| 212 |
G |
L |
-2.2670 |
|
| 213 |
E |
L |
-2.4979 |
|