Project name: 5bvj:B
Status: done
submitted: 2019-03-20 15:48:20, status changed: 2019-03-20 17:21:42
Settings
|
Chain sequence(s)
|
B: VQLVESGGGVVQPGRSLRLSCAASGFTFSVYGMNWVRQAPGKGLEWVAIIWYDGDNQYYADSVKGRFTISRDNSKNTLYLQMNGLRAEDTAVYYCARDLRTGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKT
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.9053
-
Maximal score value
-
2.5024
-
Average score
-
-0.5916
-
Total score value
-
-131.9315
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
V |
B |
0.7692 |
|
| 3 |
Q |
B |
-0.4231 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
V |
B |
0.1767 |
|
| 6 |
E |
B |
0.0000 |
|
| 7 |
S |
B |
-0.3546 |
|
| 8 |
G |
B |
-0.6135 |
|
| 9 |
G |
B |
0.0435 |
|
| 10 |
G |
B |
0.5796 |
|
| 11 |
V |
B |
0.8955 |
|
| 12 |
V |
B |
0.0000 |
|
| 13 |
Q |
B |
-1.6233 |
|
| 14 |
P |
B |
-1.9553 |
|
| 15 |
G |
B |
-2.1477 |
|
| 16 |
R |
B |
-2.7678 |
|
| 17 |
S |
B |
-2.0923 |
|
| 18 |
L |
B |
-1.5553 |
|
| 19 |
R |
B |
-2.2217 |
|
| 20 |
L |
B |
0.0000 |
|
| 21 |
S |
B |
-0.4907 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
A |
B |
-0.4283 |
|
| 24 |
A |
B |
0.0000 |
|
| 25 |
S |
B |
-0.5780 |
|
| 26 |
G |
B |
-0.1645 |
|
| 27 |
F |
B |
0.2421 |
|
| 28 |
T |
B |
0.2798 |
|
| 29 |
F |
B |
0.0000 |
|
| 30 |
S |
B |
-0.0831 |
|
| 31 |
V |
B |
0.7565 |
|
| 32 |
Y |
B |
0.5334 |
|
| 33 |
G |
B |
0.0000 |
|
| 34 |
M |
B |
0.0000 |
|
| 35 |
N |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.4117 |
|
| 40 |
A |
B |
-1.0279 |
|
| 41 |
P |
B |
-0.9662 |
|
| 42 |
G |
B |
-1.4510 |
|
| 43 |
K |
B |
-2.1132 |
|
| 44 |
G |
B |
-0.9701 |
|
| 45 |
L |
B |
0.4845 |
|
| 46 |
E |
B |
-0.3805 |
|
| 47 |
W |
B |
0.0005 |
|
| 48 |
V |
B |
0.0000 |
|
| 49 |
A |
B |
0.0000 |
|
| 50 |
I |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
W |
B |
-0.6745 |
|
| 53 |
Y |
B |
-0.3017 |
|
| 54 |
D |
B |
-1.8472 |
|
| 55 |
G |
B |
-2.0370 |
|
| 56 |
D |
B |
-2.8581 |
|
| 57 |
N |
B |
-2.1967 |
|
| 58 |
Q |
B |
-0.7604 |
|
| 59 |
Y |
B |
0.3919 |
|
| 60 |
Y |
B |
-0.4825 |
|
| 61 |
A |
B |
-1.1464 |
|
| 62 |
D |
B |
-2.2513 |
|
| 63 |
S |
B |
-1.7305 |
|
| 64 |
V |
B |
0.0000 |
|
| 65 |
K |
B |
-2.4237 |
|
| 66 |
G |
B |
-1.8573 |
|
| 67 |
R |
B |
-1.5922 |
|
| 68 |
F |
B |
0.0000 |
|
| 69 |
T |
B |
-0.9169 |
|
| 70 |
I |
B |
0.0000 |
|
| 71 |
S |
B |
-0.9312 |
|
| 72 |
R |
B |
-1.1665 |
|
| 73 |
D |
B |
-1.6928 |
|
| 74 |
N |
B |
-1.7912 |
|
| 75 |
S |
B |
-1.6679 |
|
| 76 |
K |
B |
-2.4761 |
|
| 77 |
N |
B |
-1.9713 |
|
| 78 |
T |
B |
0.0000 |
|
| 79 |
L |
B |
0.0000 |
|
| 80 |
Y |
B |
-0.4941 |
|
| 81 |
L |
B |
0.0000 |
|
| 82 |
Q |
B |
-1.6100 |
|
| 83 |
M |
B |
0.0000 |
|
| 84 |
N |
B |
-2.1242 |
|
| 85 |
G |
B |
-1.8721 |
|
| 86 |
L |
B |
0.0000 |
|
| 87 |
R |
B |
-2.5516 |
|
| 88 |
A |
B |
-1.7007 |
|
| 89 |
E |
B |
-2.2644 |
|
| 90 |
D |
B |
0.0000 |
|
| 91 |
T |
B |
-0.5140 |
|
| 92 |
A |
B |
0.0000 |
|
| 93 |
V |
B |
0.8330 |
|
| 94 |
Y |
B |
0.0000 |
|
| 95 |
Y |
B |
0.4127 |
|
| 96 |
C |
B |
0.0000 |
|
| 97 |
A |
B |
0.0000 |
|
| 98 |
R |
B |
0.0000 |
|
| 99 |
D |
B |
0.0000 |
|
| 100 |
L |
B |
-0.2743 |
|
| 101 |
R |
B |
-1.3310 |
|
| 102 |
T |
B |
-0.6812 |
|
| 103 |
G |
B |
-0.8394 |
|
| 104 |
P |
B |
-0.3913 |
|
| 105 |
F |
B |
0.2298 |
|
| 106 |
D |
B |
0.2267 |
|
| 107 |
Y |
B |
0.9087 |
|
| 108 |
W |
B |
0.6193 |
|
| 109 |
G |
B |
-0.0477 |
|
| 110 |
Q |
B |
-1.0023 |
|
| 111 |
G |
B |
0.0000 |
|
| 112 |
T |
B |
0.4339 |
|
| 113 |
L |
B |
1.4357 |
|
| 114 |
V |
B |
0.0000 |
|
| 115 |
T |
B |
0.0886 |
|
| 116 |
V |
B |
0.0000 |
|
| 117 |
S |
B |
-0.6588 |
|
| 118 |
S |
B |
-0.5094 |
|
| 119 |
A |
B |
-0.3487 |
|
| 120 |
S |
B |
-0.4669 |
|
| 121 |
T |
B |
-0.5379 |
|
| 122 |
K |
B |
-1.1138 |
|
| 123 |
G |
B |
-1.4140 |
|
| 124 |
P |
B |
0.0000 |
|
| 125 |
S |
B |
-0.1783 |
|
| 126 |
V |
B |
0.0000 |
|
| 127 |
F |
B |
0.7483 |
|
| 128 |
P |
B |
-0.0131 |
|
| 129 |
L |
B |
0.3620 |
|
| 130 |
A |
B |
-1.1148 |
|
| 131 |
P |
B |
0.0000 |
|
| 132 |
S |
B |
-1.3372 |
|
| 133 |
S |
B |
-1.5656 |
|
| 134 |
K |
B |
-1.9006 |
|
| 135 |
S |
B |
-1.0245 |
|
| 136 |
T |
B |
-0.9929 |
|
| 137 |
S |
B |
-0.9466 |
|
| 138 |
G |
B |
-0.8952 |
|
| 139 |
G |
B |
-0.9248 |
|
| 140 |
T |
B |
-0.6735 |
|
| 141 |
A |
B |
0.0000 |
|
| 142 |
A |
B |
-0.1807 |
|
| 143 |
L |
B |
0.0000 |
|
| 144 |
G |
B |
0.0000 |
|
| 145 |
C |
B |
0.0000 |
|
| 146 |
L |
B |
0.7225 |
|
| 147 |
V |
B |
0.0000 |
|
| 148 |
K |
B |
-0.2284 |
|
| 149 |
D |
B |
-0.5311 |
|
| 150 |
Y |
B |
0.0000 |
|
| 151 |
F |
B |
0.0000 |
|
| 152 |
P |
B |
-0.4674 |
|
| 153 |
E |
B |
-0.6759 |
|
| 154 |
P |
B |
-0.9305 |
|
| 155 |
V |
B |
-0.7509 |
|
| 156 |
T |
B |
-0.5688 |
|
| 157 |
V |
B |
-0.1939 |
|
| 158 |
S |
B |
-0.2818 |
|
| 159 |
W |
B |
0.0000 |
|
| 160 |
N |
B |
-0.7766 |
|
| 161 |
S |
B |
-0.5804 |
|
| 162 |
G |
B |
-0.3685 |
|
| 163 |
A |
B |
-0.1749 |
|
| 164 |
L |
B |
0.0239 |
|
| 165 |
T |
B |
-0.2571 |
|
| 166 |
S |
B |
-0.3625 |
|
| 167 |
G |
B |
-0.4485 |
|
| 168 |
V |
B |
0.0323 |
|
| 169 |
H |
B |
-0.4456 |
|
| 170 |
T |
B |
0.1084 |
|
| 171 |
F |
B |
0.8261 |
|
| 172 |
P |
B |
0.5804 |
|
| 173 |
A |
B |
1.1739 |
|
| 174 |
V |
B |
2.5024 |
|
| 175 |
L |
B |
2.1537 |
|
| 176 |
Q |
B |
0.7397 |
|
| 177 |
S |
B |
0.1202 |
|
| 178 |
S |
B |
-0.1648 |
|
| 179 |
G |
B |
0.2248 |
|
| 180 |
L |
B |
0.3030 |
|
| 181 |
Y |
B |
0.7817 |
|
| 182 |
S |
B |
0.0000 |
|
| 183 |
L |
B |
0.0000 |
|
| 184 |
S |
B |
0.6193 |
|
| 185 |
S |
B |
0.0000 |
|
| 186 |
V |
B |
0.4819 |
|
| 187 |
V |
B |
0.0000 |
|
| 188 |
T |
B |
-0.2062 |
|
| 189 |
V |
B |
0.0000 |
|
| 190 |
P |
B |
-0.5681 |
|
| 191 |
S |
B |
-0.5836 |
|
| 192 |
S |
B |
-0.5914 |
|
| 193 |
S |
B |
-0.6040 |
|
| 194 |
L |
B |
-0.7440 |
|
| 195 |
G |
B |
-0.9429 |
|
| 196 |
T |
B |
-0.7528 |
|
| 197 |
Q |
B |
-1.2962 |
|
| 198 |
T |
B |
-1.2709 |
|
| 199 |
Y |
B |
0.0000 |
|
| 200 |
I |
B |
-1.5296 |
|
| 201 |
C |
B |
0.0000 |
|
| 202 |
N |
B |
-1.5449 |
|
| 203 |
V |
B |
0.0000 |
|
| 204 |
N |
B |
-1.8742 |
|
| 205 |
H |
B |
0.0000 |
|
| 206 |
K |
B |
-2.7611 |
|
| 207 |
P |
B |
-1.6655 |
|
| 208 |
S |
B |
-1.8391 |
|
| 209 |
N |
B |
-2.5866 |
|
| 210 |
T |
B |
-2.0881 |
|
| 211 |
K |
B |
-2.7410 |
|
| 212 |
V |
B |
-1.7968 |
|
| 213 |
D |
B |
-2.7904 |
|
| 214 |
K |
B |
-2.5008 |
|
| 215 |
R |
B |
-2.8490 |
|
| 216 |
V |
B |
0.0000 |
|
| 217 |
E |
B |
-2.9053 |
|
| 218 |
P |
B |
-2.0570 |
|
| 219 |
K |
B |
-2.2552 |
|
| 220 |
S |
B |
-1.6408 |
|
| 221 |
C |
B |
-1.0488 |
|
| 222 |
D |
B |
-2.5565 |
|
| 223 |
K |
B |
-2.4698 |
|
| 224 |
T |
B |
-1.4206 |
|