Project name: 5vh3:H

Chain sequence(s)	H: EVKLEESGGGLVQPGGSMKLSCVASGFIFSNHWMNWVRQSPEKGLEWVAEIRSKSINSATHYAESVKGRFTISRDDSKSAVYLQMTDLRTEDTGVYYCSRNYYGSTYDYWGQGTTLTVSSASTKGPSVFPLAPSSKGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9512
• Maximal score value: 2.513
• Average score: -0.6038
• Total score value: -131.6385

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1986
2	V	H	-1.3658
3	K	H	-2.1362
4	L	H	0.0000
5	E	H	-1.9394
6	E	H	-1.1271
7	S	H	-1.1406
8	G	H	-1.0924
9	G	H	-0.6811
10	G	H	-0.1669
11	L	H	0.4035
12	V	H	-0.4205
13	Q	H	-1.6606
14	P	H	-1.9099
15	G	H	-1.8675
16	G	H	-1.3304
17	S	H	-1.4901
18	M	H	-1.1943
19	K	H	-2.1755
20	L	H	0.0000
21	S	H	-0.8043
22	C	H	0.0000
23	V	H	-0.4285
24	A	H	0.0000
25	S	H	-0.9210
26	G	H	-0.8486
27	F	H	0.3809
28	I	H	1.5896
29	F	H	0.0000
30	S	H	-0.7228
31	N	H	-0.8904
32	H	H	0.0000
33	W	H	-0.1930
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6262
40	S	H	0.0000
41	P	H	-1.4920
42	E	H	-2.7852
43	K	H	-2.4108
44	G	H	-1.0095
45	L	H	0.5698
46	E	H	0.0844
47	W	H	0.4943
48	V	H	0.0000
49	A	H	0.0000
50	E	H	0.0000
51	I	H	0.0000
52	R	H	-1.0303
53	S	H	0.0000
54	K	H	-2.2099
55	S	H	-1.0543
56	I	H	-0.1248
57	N	H	-1.3862
58	S	H	-1.2660
59	A	H	-0.6920
60	T	H	-0.5441
61	H	H	-1.0051
62	Y	H	-1.1664
63	A	H	0.0000
64	E	H	-2.5750
65	S	H	-1.7630
66	V	H	0.0000
67	K	H	-2.6983
68	G	H	-1.8301
69	R	H	-1.7239
70	F	H	0.0000
71	T	H	-0.9831
72	I	H	0.0000
73	S	H	-0.4531
74	R	H	-0.9419
75	D	H	-1.1802
76	D	H	-1.3218
77	S	H	-1.3561
78	K	H	-1.9433
79	S	H	-0.6957
80	A	H	0.0000
81	V	H	0.0000
82	Y	H	-0.5111
83	L	H	0.0000
84	Q	H	-1.5611
85	M	H	0.0000
86	T	H	-1.6524
87	D	H	-2.2932
88	L	H	0.0000
89	R	H	-2.7317
90	T	H	-1.9400
91	E	H	-2.7537
92	D	H	0.0000
93	T	H	-0.9404
94	G	H	-0.7133
95	V	H	0.0177
96	Y	H	0.0000
97	Y	H	-0.0473
98	C	H	0.0000
99	S	H	0.0000
100	R	H	0.0000
101	N	H	0.0000
102	Y	H	1.0727
103	Y	H	0.6630
104	G	H	0.0412
105	S	H	0.0043
106	T	H	0.1977
107	Y	H	0.5414
108	D	H	0.1624
109	Y	H	0.5668
110	W	H	0.0149
111	G	H	-0.9457
112	Q	H	-1.6779
113	G	H	-0.9043
114	T	H	-0.7046
115	T	H	-0.2821
116	L	H	0.0000
117	T	H	-0.5058
118	V	H	0.0000
119	S	H	-0.9393
120	S	H	-0.6971
121	A	H	-0.4582
122	S	H	-0.6418
123	T	H	-0.6462
124	K	H	-1.1499
125	G	H	-1.4890
126	P	H	0.0000
127	S	H	-0.0453
128	V	H	0.0000
129	F	H	1.0430
130	P	H	-0.0031
131	L	H	0.3527
132	A	H	-0.9373
133	P	H	0.0000
134	S	H	-1.3381
135	S	H	-1.5120
136	K	H	-1.8859
141	G	H	-0.6433
142	T	H	-0.4706
143	A	H	-0.5134
144	A	H	0.0843
145	L	H	0.0000
146	G	H	0.0000
147	C	H	0.0000
148	L	H	0.7692
149	V	H	0.0000
150	K	H	-0.2042
151	D	H	-0.5473
152	Y	H	0.0000
153	F	H	0.0000
154	P	H	-0.7298
155	E	H	-1.1898
156	P	H	-1.2323
157	V	H	-1.0188
158	T	H	-0.8279
159	V	H	-0.4536
160	S	H	-0.3307
161	W	H	0.0000
162	N	H	-0.6488
163	S	H	-0.5330
164	G	H	-0.5072
165	A	H	-0.2391
166	L	H	-0.0301
167	T	H	-0.2936
168	S	H	-0.3709
169	G	H	-0.4608
170	V	H	0.0638
171	H	H	-0.3452
172	T	H	0.2604
173	F	H	1.0302
174	P	H	0.7234
175	A	H	1.1614
176	V	H	2.5130
177	L	H	2.0644
178	Q	H	0.7184
179	S	H	0.1229
180	S	H	-0.1643
181	G	H	0.2376
182	L	H	0.2292
183	Y	H	0.7206
184	S	H	0.0000
185	L	H	0.0000
186	S	H	0.7074
187	S	H	0.0000
188	V	H	0.4879
189	V	H	0.0000
190	T	H	-0.2061
191	V	H	0.0000
192	P	H	-0.4981
193	S	H	-0.7296
194	S	H	-0.5965
195	S	H	-0.5486
196	L	H	-0.7389
197	G	H	-0.9076
198	T	H	-0.6408
199	Q	H	-1.0331
200	T	H	-1.0879
201	Y	H	0.0000
202	I	H	-1.1193
203	C	H	0.0000
204	N	H	-1.2468
205	V	H	0.0000
206	N	H	-2.3480
207	H	H	0.0000
208	K	H	-2.9512
209	P	H	-1.7815
210	S	H	-1.8924
211	N	H	-2.6725
212	T	H	-2.2251
213	K	H	-2.6602
214	V	H	-1.3251
215	D	H	-1.6833
216	K	H	-1.4185
217	K	H	-2.2584
218	V	H	0.0000
219	E	H	-2.8481
220	P	H	-1.9647
221	K	H	-2.3730
222	S	H	-1.3413