Project name: 6and:H
Status: done
submitted: 2019-03-20 16:16:45, status changed: 2019-03-20 17:32:33
Settings
|
Chain sequence(s)
|
H: VQLVESGGGLVQPGGSLRLSCAASGYEFSRSWMNWVRQAPGKGLEWVGRIYPGDGDTQYSGKFKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARDGSSWDWYFDVWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-2.8638
-
Maximal score value
-
2.432
-
Average score
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-0.562
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Total score value
-
-119.7018
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
V |
H |
0.8544 |
|
| 3 |
Q |
H |
-0.3555 |
|
| 4 |
L |
H |
0.0000 |
|
| 5 |
V |
H |
0.1841 |
|
| 6 |
E |
H |
0.0000 |
|
| 7 |
S |
H |
-0.5059 |
|
| 8 |
G |
H |
-0.8537 |
|
| 9 |
G |
H |
-0.4231 |
|
| 10 |
G |
H |
-0.2156 |
|
| 11 |
L |
H |
-0.0601 |
|
| 12 |
V |
H |
0.0000 |
|
| 13 |
Q |
H |
-1.6991 |
|
| 14 |
P |
H |
-1.8742 |
|
| 15 |
G |
H |
-1.5343 |
|
| 16 |
G |
H |
-1.1677 |
|
| 17 |
S |
H |
-1.3549 |
|
| 18 |
L |
H |
-1.1771 |
|
| 19 |
R |
H |
-2.0789 |
|
| 20 |
L |
H |
0.0000 |
|
| 21 |
S |
H |
-0.4472 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
A |
H |
-0.4498 |
|
| 24 |
A |
H |
0.0000 |
|
| 25 |
S |
H |
-0.7015 |
|
| 26 |
G |
H |
-0.4172 |
|
| 27 |
Y |
H |
-0.9935 |
|
| 28 |
E |
H |
-2.3083 |
|
| 29 |
F |
H |
0.0000 |
|
| 30 |
S |
H |
-2.0544 |
|
| 31 |
R |
H |
-2.5926 |
|
| 32 |
S |
H |
-1.2955 |
|
| 33 |
W |
H |
-0.5035 |
|
| 34 |
M |
H |
0.0000 |
|
| 35 |
N |
H |
0.0000 |
|
| 36 |
W |
H |
0.0000 |
|
| 37 |
V |
H |
0.0000 |
|
| 38 |
R |
H |
0.0000 |
|
| 39 |
Q |
H |
-0.3842 |
|
| 40 |
A |
H |
-1.0572 |
|
| 41 |
P |
H |
-1.0580 |
|
| 42 |
G |
H |
-1.4115 |
|
| 43 |
K |
H |
-2.0419 |
|
| 44 |
G |
H |
-0.8803 |
|
| 45 |
L |
H |
0.6984 |
|
| 46 |
E |
H |
0.0868 |
|
| 47 |
W |
H |
0.4992 |
|
| 48 |
V |
H |
0.0000 |
|
| 49 |
G |
H |
0.0000 |
|
| 50 |
R |
H |
-0.6320 |
|
| 51 |
I |
H |
0.0000 |
|
| 52 |
Y |
H |
-1.6049 |
|
| 52A |
P |
H |
0.0000 |
|
| 53 |
G |
H |
-2.2785 |
|
| 54 |
D |
H |
-2.8638 |
|
| 55 |
G |
H |
-2.3146 |
|
| 56 |
D |
H |
-2.7066 |
|
| 57 |
T |
H |
-1.5396 |
|
| 58 |
Q |
H |
-1.3894 |
|
| 59 |
Y |
H |
-1.1994 |
|
| 60 |
S |
H |
-1.3742 |
|
| 61 |
G |
H |
-2.0610 |
|
| 62 |
K |
H |
-2.5324 |
|
| 63 |
F |
H |
0.0000 |
|
| 64 |
K |
H |
-2.7510 |
|
| 65 |
G |
H |
-1.9847 |
|
| 66 |
R |
H |
-1.6476 |
|
| 67 |
F |
H |
0.0000 |
|
| 68 |
T |
H |
-1.0049 |
|
| 69 |
I |
H |
0.0000 |
|
| 70 |
S |
H |
-0.5130 |
|
| 71 |
A |
H |
-1.0694 |
|
| 72 |
D |
H |
-1.2493 |
|
| 73 |
T |
H |
-1.8621 |
|
| 74 |
S |
H |
-1.3488 |
|
| 75 |
K |
H |
-2.2257 |
|
| 76 |
N |
H |
-1.9106 |
|
| 77 |
T |
H |
0.0000 |
|
| 78 |
A |
H |
0.0000 |
|
| 79 |
Y |
H |
-0.4233 |
|
| 80 |
L |
H |
0.0000 |
|
| 81 |
Q |
H |
-1.2092 |
|
| 82 |
M |
H |
0.0000 |
|
| 82A |
N |
H |
-1.5627 |
|
| 82B |
S |
H |
-1.3584 |
|
| 82C |
L |
H |
0.0000 |
|
| 83 |
R |
H |
-2.6470 |
|
| 84 |
A |
H |
-1.9016 |
|
| 85 |
E |
H |
-2.3268 |
|
| 86 |
D |
H |
0.0000 |
|
| 87 |
T |
H |
-0.7861 |
|
| 88 |
A |
H |
0.0000 |
|
| 89 |
V |
H |
0.3640 |
|
| 90 |
Y |
H |
0.0000 |
|
| 91 |
Y |
H |
0.4082 |
|
| 92 |
C |
H |
0.0000 |
|
| 93 |
A |
H |
0.0000 |
|
| 94 |
R |
H |
0.0109 |
|
| 95 |
D |
H |
0.0000 |
|
| 96 |
G |
H |
0.3543 |
|
| 97 |
S |
H |
0.5912 |
|
| 98 |
S |
H |
0.3113 |
|
| 99 |
W |
H |
0.6708 |
|
| 100 |
D |
H |
-0.4461 |
|
| 100A |
W |
H |
1.1357 |
|
| 100B |
Y |
H |
1.6703 |
|
| 100C |
F |
H |
1.1314 |
|
| 101 |
D |
H |
0.0505 |
|
| 102 |
V |
H |
0.3296 |
|
| 103 |
W |
H |
0.2687 |
|
| 104 |
G |
H |
0.0000 |
|
| 105 |
Q |
H |
-1.0081 |
|
| 106 |
G |
H |
-0.1963 |
|
| 107 |
T |
H |
0.0419 |
|
| 108 |
L |
H |
0.4768 |
|
| 109 |
V |
H |
0.0000 |
|
| 110 |
T |
H |
0.0000 |
|
| 111 |
V |
H |
0.0000 |
|
| 112 |
S |
H |
-1.0852 |
|
| 113 |
S |
H |
-0.7265 |
|
| 114 |
A |
H |
-0.5253 |
|
| 115 |
S |
H |
-0.6112 |
|
| 116 |
T |
H |
-0.5858 |
|
| 117 |
K |
H |
-1.1421 |
|
| 118 |
G |
H |
-1.4561 |
|
| 119 |
P |
H |
0.0000 |
|
| 120 |
S |
H |
-0.0397 |
|
| 121 |
V |
H |
0.0000 |
|
| 122 |
F |
H |
1.0305 |
|
| 123 |
P |
H |
0.0811 |
|
| 124 |
L |
H |
0.3464 |
|
| 125 |
A |
H |
-0.4723 |
|
| 126 |
P |
H |
0.0000 |
|
| 127 |
S |
H |
-0.4047 |
|
| 134 |
G |
H |
-0.6533 |
|
| 135 |
T |
H |
-0.4657 |
|
| 136 |
A |
H |
-0.3058 |
|
| 137 |
A |
H |
0.1076 |
|
| 138 |
L |
H |
0.0000 |
|
| 139 |
G |
H |
0.0000 |
|
| 140 |
C |
H |
0.0000 |
|
| 141 |
L |
H |
0.7371 |
|
| 142 |
V |
H |
0.0000 |
|
| 143 |
K |
H |
-0.2290 |
|
| 144 |
D |
H |
-0.5784 |
|
| 145 |
Y |
H |
0.0000 |
|
| 146 |
F |
H |
0.0000 |
|
| 147 |
P |
H |
0.0000 |
|
| 148 |
E |
H |
-0.6649 |
|
| 149 |
P |
H |
-0.8053 |
|
| 150 |
V |
H |
-0.7744 |
|
| 151 |
T |
H |
-0.6665 |
|
| 152 |
V |
H |
-0.4731 |
|
| 153 |
S |
H |
-0.4492 |
|
| 154 |
W |
H |
0.0000 |
|
| 155 |
N |
H |
-0.8192 |
|
| 156 |
S |
H |
-0.7040 |
|
| 157 |
G |
H |
-0.5498 |
|
| 158 |
A |
H |
-0.2575 |
|
| 159 |
L |
H |
-0.0566 |
|
| 160 |
T |
H |
-0.3007 |
|
| 161 |
S |
H |
-0.3690 |
|
| 162 |
G |
H |
-0.4615 |
|
| 163 |
V |
H |
0.0547 |
|
| 164 |
H |
H |
-0.3561 |
|
| 165 |
T |
H |
0.2491 |
|
| 166 |
F |
H |
0.9812 |
|
| 167 |
P |
H |
0.6954 |
|
| 168 |
A |
H |
1.2007 |
|
| 169 |
V |
H |
2.4320 |
|
| 170 |
L |
H |
2.0313 |
|
| 171 |
Q |
H |
0.6068 |
|
| 172 |
S |
H |
0.0609 |
|
| 173 |
S |
H |
-0.2092 |
|
| 174 |
G |
H |
0.2102 |
|
| 175 |
L |
H |
0.2789 |
|
| 176 |
Y |
H |
0.7470 |
|
| 177 |
S |
H |
0.0000 |
|
| 178 |
L |
H |
0.0000 |
|
| 179 |
S |
H |
0.6672 |
|
| 180 |
S |
H |
0.0000 |
|
| 181 |
V |
H |
0.4653 |
|
| 182 |
V |
H |
0.0000 |
|
| 183 |
T |
H |
-0.2187 |
|
| 184 |
V |
H |
0.0000 |
|
| 185 |
P |
H |
-0.6009 |
|
| 186 |
S |
H |
-0.5798 |
|
| 187 |
S |
H |
-0.6298 |
|
| 188 |
S |
H |
-0.6008 |
|
| 189 |
L |
H |
-0.8534 |
|
| 190 |
G |
H |
-0.9863 |
|
| 191 |
T |
H |
-0.6823 |
|
| 192 |
Q |
H |
-1.1561 |
|
| 193 |
T |
H |
-1.1709 |
|
| 194 |
Y |
H |
0.0000 |
|
| 195 |
I |
H |
-1.5524 |
|
| 196 |
C |
H |
0.0000 |
|
| 197 |
N |
H |
-1.6596 |
|
| 198 |
V |
H |
0.0000 |
|
| 199 |
N |
H |
-2.1560 |
|
| 200 |
H |
H |
0.0000 |
|
| 201 |
K |
H |
-2.7863 |
|
| 202 |
P |
H |
-1.6283 |
|
| 203 |
S |
H |
-1.8429 |
|
| 204 |
N |
H |
-2.5835 |
|
| 205 |
T |
H |
-2.1259 |
|
| 206 |
K |
H |
-2.7824 |
|
| 207 |
V |
H |
-1.8748 |
|
| 208 |
D |
H |
-2.7334 |
|
| 209 |
K |
H |
-2.2193 |
|
| 210 |
R |
H |
-2.6765 |
|
| 211 |
V |
H |
0.0000 |
|
| 212 |
E |
H |
-2.5305 |
|
| 213 |
P |
H |
-1.1690 |
|