Project name: 4np4:L

Chain sequence(s)	L: EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSTWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.717
• Maximal score value: 2.1571
• Average score: -0.8222
• Total score value: -175.133

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	L	-1.5689
2	I	L	0.1037
3	V	L	0.9004
4	L	L	0.0000
5	T	L	-0.4696
6	Q	L	0.0000
7	S	L	-0.9833
8	P	L	-0.6943
9	G	L	-1.1756
10	T	L	-0.8375
11	L	L	-0.5453
12	S	L	-0.6400
13	L	L	-0.9432
14	S	L	-1.5445
15	P	L	-2.1545
16	G	L	-2.6133
17	E	L	-3.0734
18	R	L	-3.2244
19	A	L	0.0000
20	T	L	-0.6755
21	L	L	0.0000
22	S	L	-0.9866
23	C	L	0.0000
24	R	L	-2.2424
25	A	L	0.0000
26	S	L	-0.9932
27	Q	L	-1.6931
28	S	L	-1.2594
29	V	L	-0.6360
30	S	L	-0.0607
31	S	L	-0.0664
32	S	L	0.2499
33	Y	L	0.9225
34	L	L	0.0000
35	A	L	0.0000
36	W	L	0.0000
37	Y	L	0.3676
38	Q	L	0.0000
39	Q	L	-1.2448
40	K	L	-1.5561
41	P	L	-1.2577
42	G	L	-1.2646
43	Q	L	-1.8319
44	A	L	-1.1615
45	P	L	-1.0721
46	R	L	-1.1593
47	L	L	0.1154
48	L	L	0.0000
49	I	L	0.0000
50	Y	L	1.0253
51	G	L	0.2504
52	A	L	0.0000
53	S	L	-0.5545
54	S	L	-0.5817
55	R	L	-1.3297
56	A	L	-0.4101
57	T	L	-0.4650
58	G	L	-0.8266
59	I	L	-0.9115
60	P	L	-1.2462
61	D	L	-2.1935
62	R	L	-2.0039
63	F	L	0.0000
64	S	L	-1.0077
65	G	L	-0.4639
66	S	L	-0.8185
67	G	L	-1.2807
68	S	L	-1.2091
69	G	L	-1.2770
70	T	L	-1.9456
71	D	L	-2.7427
72	F	L	0.0000
73	T	L	-0.9072
74	L	L	0.0000
75	T	L	-0.8272
76	I	L	0.0000
77	S	L	-2.5112
78	R	L	-3.5167
79	L	L	0.0000
80	E	L	-2.7009
81	P	L	-1.7697
82	E	L	-2.3874
83	D	L	0.0000
84	F	L	0.0000
85	A	L	0.0000
86	V	L	0.0000
87	Y	L	0.0000
88	Y	L	0.1400
89	C	L	0.0000
90	Q	L	0.0000
91	Q	L	0.0000
92	Y	L	0.9816
93	G	L	0.3308
94	S	L	-0.2908
95	S	L	0.0495
96	T	L	0.3987
97	W	L	1.6478
98	T	L	1.4899
99	F	L	2.1571
100	G	L	0.0000
101	Q	L	-0.8166
102	G	L	0.0000
103	T	L	0.0000
104	K	L	-1.7709
105	V	L	0.0000
106	E	L	-0.9474
107	I	L	-0.7703
108	K	L	-1.1192
109	R	L	-0.8200
110	T	L	-0.0000
111	V	L	0.5776
112	A	L	0.0227
113	A	L	-0.2168
114	P	L	0.0000
115	S	L	-0.0884
116	V	L	0.0000
117	F	L	1.1795
118	I	L	1.1428
119	F	L	1.3633
120	P	L	-0.1424
121	P	L	0.0000
122	S	L	-1.8364
123	D	L	-3.2967
124	E	L	-3.5378
125	Q	L	-2.8195
126	L	L	-2.6467
127	K	L	-3.1437
128	S	L	-2.0729
129	G	L	-1.2676
130	T	L	-1.0811
131	A	L	0.0000
132	S	L	-0.0302
133	V	L	0.0000
134	V	L	0.6520
135	C	L	0.0000
136	L	L	0.4961
137	L	L	0.0000
138	N	L	-0.5923
139	N	L	-1.2252
140	F	L	0.0000
141	Y	L	0.0000
142	P	L	-1.5771
143	R	L	-2.6425
144	E	L	-3.0021
145	A	L	-2.0473
146	K	L	-1.8331
147	V	L	-0.8220
148	Q	L	-0.3233
149	W	L	0.0000
150	K	L	-0.4141
151	V	L	0.0000
152	D	L	-1.7290
153	N	L	-1.2317
154	A	L	-0.1669
155	L	L	0.8031
156	Q	L	-0.2210
157	S	L	-0.5929
158	G	L	-1.3338
159	N	L	-1.6401
160	S	L	-1.7686
161	Q	L	-2.4500
162	E	L	-2.3461
163	S	L	-1.3385
164	V	L	-0.7872
165	T	L	-1.0739
166	E	L	-2.3159
167	Q	L	-2.1333
168	D	L	-2.4849
169	S	L	-2.0702
170	K	L	-2.6533
171	D	L	-2.4238
172	S	L	-2.0640
173	T	L	0.0000
174	Y	L	0.0000
175	S	L	-0.9882
176	L	L	0.0000
177	S	L	-0.5100
178	S	L	0.0000
179	T	L	-0.7828
180	L	L	0.0000
181	T	L	-0.6907
182	L	L	-0.8250
183	S	L	-1.0552
184	K	L	-2.1085
185	A	L	-1.8812
186	D	L	-2.6201
187	Y	L	0.0000
188	E	L	-3.7170
189	K	L	-3.6506
190	H	L	-3.1842
191	K	L	-3.2476
192	V	L	-1.6174
193	Y	L	0.0000
194	A	L	0.0000
195	C	L	0.0000
196	E	L	-0.6553
197	V	L	0.0000
198	T	L	-1.0987
199	H	L	0.0000
200	Q	L	-1.4030
201	G	L	-0.4020
202	L	L	-0.2261
203	S	L	-0.4199
204	S	L	-0.4348
205	P	L	-0.5931
206	V	L	-0.0579
207	T	L	-0.4035
208	K	L	-0.4193
209	S	L	-0.3401
210	F	L	-0.9202
211	N	L	-2.3379
212	R	L	-2.7794
213	G	L	-1.5942