Project name: mab5

Chain sequence(s)	H: EVQLVQSGAEVKKPGSSVKVSCKASGGTFSTYGISWVRQAPGQGLEWIGGIIPIFDAGNSAQSFQGRVTITADESTSTANMEVSSLRSEQTAVYYCASSSRIYDHHIQKGGYYDMQVWGQGTMVTVS; L: AVLTQPSSVSTPPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAWVFGGGTKLTVLRT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0528
• Maximal score value: 1.7925
• Average score: -0.5993
• Total score value: -142.6417

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.3598
2	V	H	0.2287
3	Q	H	-0.9570
4	L	H	0.0000
5	V	H	-0.1282
6	Q	H	0.0000
7	S	H	-0.7852
8	G	H	-0.6801
9	A	H	-0.0755
10	E	H	-0.3710
11	V	H	0.7251
12	K	H	-1.1024
13	K	H	-2.1502
14	P	H	-2.0503
15	G	H	-1.5496
16	S	H	-1.2623
17	S	H	-1.5527
18	V	H	0.0000
19	K	H	-2.2066
20	V	H	0.0000
21	S	H	-0.8954
22	C	H	0.0000
23	K	H	-1.4996
24	A	H	0.0000
25	S	H	-0.9229
26	G	H	-1.0678
27	G	H	-1.0001
28	T	H	-0.8328
29	F	H	0.0000
30	S	H	0.2426
31	T	H	1.1403
32	Y	H	1.1857
33	G	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6389
40	A	H	0.0000
41	P	H	-1.1195
42	G	H	-1.2298
43	Q	H	-1.7431
44	G	H	-1.0161
45	L	H	0.0000
46	E	H	-0.5952
47	W	H	0.0000
48	I	H	0.0000
49	G	H	0.0000
50	G	H	0.0000
51	I	H	0.0000
52	I	H	0.2062
52A	P	H	0.0000
53	I	H	0.7612
54	F	H	0.5909
55	D	H	-1.3409
56	A	H	-0.7509
57	G	H	-1.1322
58	N	H	-1.4144
59	S	H	-1.4480
60	A	H	-1.1063
61	Q	H	-1.9714
62	S	H	-1.4660
63	F	H	0.0000
64	Q	H	-2.5880
65	G	H	-2.1274
66	R	H	-2.7092
67	V	H	-1.7536
68	T	H	-1.2848
69	I	H	-0.6883
70	T	H	-0.8305
71	A	H	-1.1553
72	D	H	-1.7714
73	E	H	-1.6591
74	S	H	-1.0670
75	T	H	-1.1441
76	S	H	0.0000
77	T	H	0.0000
78	A	H	0.0000
79	N	H	-1.0867
80	M	H	0.0000
81	E	H	-1.8290
82	V	H	0.0000
82A	S	H	-1.5273
82B	S	H	-1.3685
82C	L	H	0.0000
83	R	H	-3.0528
84	S	H	-2.4255
85	E	H	-2.6374
86	Q	H	-1.6881
87	T	H	-0.8358
88	A	H	0.0000
89	V	H	0.2464
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	S	H	0.0000
95	S	H	0.0000
96	S	H	0.5225
97	R	H	0.0000
98	I	H	1.7925
99	Y	H	1.3047
100	D	H	-0.7209
100A	H	H	-0.4200
100B	H	H	-0.8822
100C	I	H	0.2966
100D	Q	H	-1.2107
100E	K	H	-1.2897
100F	G	H	0.0000
100G	G	H	0.0000
100H	Y	H	-0.0930
100I	Y	H	0.1248
100J	D	H	0.0000
100K	M	H	0.0000
101	Q	H	-0.6464
102	V	H	-0.2061
103	W	H	-0.3034
104	G	H	0.0000
105	Q	H	-1.0951
106	G	H	-0.4491
107	T	H	0.0000
108	M	H	0.3250
109	V	H	0.0000
110	T	H	-0.3411
111	V	H	0.0000
112	S	H	-1.1071
2	A	L	0.3093
3	V	L	1.2679
4	L	L	0.0000
5	T	L	-0.0529
6	Q	L	-0.4994
7	P	L	-0.6277
8	S	L	-0.8532
10	S	L	-0.9229
11	V	L	-0.3248
12	S	L	-0.5762
13	T	L	0.0000
14	P	L	-1.1906
15	P	L	-1.5952
16	G	L	-1.7558
17	Q	L	-2.3678
18	K	L	-2.4662
19	V	L	0.0000
20	T	L	-0.5069
21	I	L	0.0000
22	S	L	-0.3906
23	C	L	0.0000
24	S	L	-0.3302
25	G	L	-0.2933
26	S	L	-0.7452
27	S	L	-0.9344
28	S	L	-0.6672
29	N	L	0.0000
30	I	L	0.0000
30A	G	L	-1.2237
30B	N	L	-1.3929
31	N	L	0.0000
32	Y	L	0.1514
33	V	L	0.0000
34	S	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	L	L	-0.2634
40	P	L	-0.4367
41	G	L	-0.4332
42	T	L	-0.5873
43	A	L	-0.5726
44	P	L	0.0000
45	K	L	-1.2361
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.4465
50	D	L	-0.7666
51	N	L	-1.2918
52	N	L	-2.4174
53	K	L	-2.8392
54	R	L	-2.3476
55	P	L	-1.0879
56	S	L	-0.7746
57	G	L	-0.9676
58	I	L	0.0000
59	P	L	-1.4861
60	D	L	-2.4779
61	R	L	-1.6654
62	F	L	0.0000
63	S	L	-1.6993
64	G	L	-1.3623
65	S	L	-1.3057
66	K	L	-1.0469
67	S	L	-0.8182
68	G	L	-1.0854
69	T	L	-0.9801
70	S	L	-0.7251
71	A	L	0.0000
72	T	L	-0.6050
73	L	L	0.0000
74	G	L	-0.6450
75	I	L	0.0000
76	T	L	-1.8097
77	G	L	-1.7107
78	L	L	0.0000
79	Q	L	-1.8531
80	T	L	-1.3306
81	G	L	-1.1525
82	D	L	0.0000
83	E	L	-1.7335
84	A	L	0.0000
85	D	L	-1.2243
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	G	L	0.0000
90	T	L	0.0000
91	W	L	0.0000
92	D	L	0.0000
93	S	L	-0.7367
94	S	L	-0.1778
95	L	L	0.2274
95A	S	L	-0.1845
95B	A	L	0.0000
96	W	L	0.2499
97	V	L	0.0000
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-0.6476
101	G	L	-0.9946
102	T	L	0.0000
103	K	L	-2.0564
104	L	L	0.0000
105	T	L	-0.8335
106	V	L	0.0000
107	L	L	-0.2252
108	R	L	-1.5415
109	T	L	-0.8238