Project name: 40d722a94a160d0

Chain sequence(s)	H: VQLQQSGPEMVKPGASVKMSCKASGYTFTNYVLHWVKQKPGQGLEWIGYINPYNDGTNYNAKFKDKATLTSDKSSSTAYMELSSLTSEDSAVYYCSKGGYYTLDYWGQGTSVTVSS; L: DVVMTQTPLSLPVSFGDQASISCRSSQSLVHSKGNTYLHWYLQKPGQSPKLLIYKISNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCSQSTHVPFTFGSGTKLEIK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.273
• Maximal score value: 1.8469
• Average score: -0.624
• Total score value: -142.2824

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	1.1698
3	Q	H	-0.7821
4	L	H	0.0000
5	Q	H	-1.8167
6	Q	H	0.0000
7	S	H	-1.1907
8	G	H	-1.1108
9	P	H	-0.7483
10	E	H	-0.9245
11	M	H	0.2455
12	V	H	-0.4851
13	K	H	-1.6442
14	P	H	-1.2437
15	G	H	-1.0410
16	A	H	-0.8414
17	S	H	-1.1130
18	V	H	0.0000
19	K	H	-2.1572
20	M	H	0.0000
21	S	H	0.0000
22	C	H	0.0000
23	K	H	-1.7402
24	A	H	0.0000
25	S	H	-0.5419
26	G	H	0.0451
27	Y	H	0.0585
28	T	H	-0.0966
29	F	H	0.0000
30	T	H	-0.7748
31	N	H	-0.8864
32	Y	H	0.0959
33	V	H	0.0000
34	L	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	K	H	0.0000
39	Q	H	0.0000
40	K	H	-1.5370
41	P	H	-1.0013
42	G	H	-1.3202
43	Q	H	-1.8837
44	G	H	-1.2050
45	L	H	0.0000
46	E	H	-1.5594
47	W	H	0.0000
48	I	H	0.0000
49	G	H	0.0000
50	Y	H	0.0000
51	I	H	0.0000
52	N	H	-1.1646
52A	P	H	0.0000
53	Y	H	-0.6193
54	N	H	-1.8777
55	D	H	-2.7092
56	G	H	-1.8492
57	T	H	-1.3054
58	N	H	-1.3668
59	Y	H	-1.2745
60	N	H	-1.3961
61	A	H	-1.8287
62	K	H	-2.7104
63	F	H	0.0000
64	K	H	-3.2730
65	D	H	-3.1193
66	K	H	-2.1659
67	A	H	0.0000
68	T	H	-1.1796
69	L	H	0.0000
70	T	H	-1.0514
71	S	H	-1.3502
72	D	H	-1.9412
73	K	H	-2.3626
74	S	H	-1.4172
75	S	H	-1.3117
76	S	H	-1.3784
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.6637
80	M	H	0.0000
81	E	H	-1.6034
82	L	H	0.0000
82A	S	H	-1.1620
82B	S	H	-1.0592
82C	L	H	0.0000
83	T	H	-1.1855
84	S	H	-1.4188
85	E	H	-1.9981
86	D	H	0.0000
87	S	H	-0.7395
88	A	H	0.0000
89	V	H	-0.1323
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	S	H	0.0000
94	K	H	0.0000
95	G	H	0.0000
96	G	H	0.4786
97	Y	H	1.8469
98	Y	H	1.8358
99	T	H	0.8863
100	L	H	0.0000
101	D	H	-0.2960
102	Y	H	0.4096
103	W	H	-0.2362
104	G	H	0.0000
105	Q	H	-1.9084
106	G	H	0.0000
107	T	H	0.0000
108	S	H	-0.4693
109	V	H	0.0000
110	T	H	-0.3762
111	V	H	-0.7553
112	S	H	-0.6548
113	S	H	-0.6708
1	D	L	-1.2126
2	V	L	-0.0672
3	V	L	0.9958
4	M	L	0.0000
5	T	L	0.0799
6	Q	L	0.0000
7	T	L	0.1801
8	P	L	0.4225
9	L	L	1.2042
10	S	L	0.1679
11	L	L	-0.1223
12	P	L	-0.6451
13	V	L	0.0000
14	S	L	-0.9823
15	F	L	-0.4469
16	G	L	-1.7027
17	D	L	-2.4470
18	Q	L	-2.7852
19	A	L	0.0000
20	S	L	-0.8255
21	I	L	0.0000
22	S	L	-0.8132
23	C	L	0.0000
24	R	L	-1.4170
25	S	L	0.0000
26	S	L	-0.7769
27	Q	L	-1.3789
28	S	L	-0.8024
29	L	L	0.0000
30	V	L	0.1125
30A	H	L	-0.6886
30B	S	L	-1.1365
30C	K	L	-2.0878
30D	G	L	-1.3832
30E	N	L	-1.1573
31	T	L	-0.3582
32	Y	L	0.1548
33	L	L	0.0000
34	H	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	L	L	0.0000
38	Q	L	-1.2839
39	K	L	-1.6818
40	P	L	-1.0975
41	G	L	-1.4875
42	Q	L	-2.2513
43	S	L	-1.6773
44	P	L	0.0000
45	K	L	-1.9402
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.0724
50	K	L	-0.5554
51	I	L	-0.3256
52	S	L	-0.5070
53	N	L	-0.7474
54	R	L	-1.0298
55	F	L	-0.3605
56	S	L	-0.4276
57	G	L	-0.7272
58	V	L	-0.7772
59	P	L	-1.2740
60	D	L	-2.2075
61	R	L	-2.2542
62	F	L	0.0000
63	S	L	-1.2091
64	G	L	0.0000
65	S	L	-0.8943
66	G	L	-1.0580
67	S	L	-0.8437
68	G	L	-0.8589
69	T	L	-1.5018
70	D	L	-2.4438
71	F	L	0.0000
72	T	L	-0.9534
73	L	L	0.0000
74	K	L	-1.6789
75	I	L	0.0000
76	S	L	-2.5626
77	R	L	-3.1301
78	V	L	0.0000
79	E	L	-2.4857
80	A	L	-1.2176
81	E	L	-2.2437
82	D	L	0.0000
83	L	L	-0.7014
84	G	L	0.0000
85	V	L	-0.1540
86	Y	L	0.0000
87	F	L	0.0000
88	C	L	0.0000
89	S	L	0.0000
90	Q	L	0.0000
91	S	L	0.0000
92	T	L	0.0000
93	H	L	0.2759
94	V	L	1.3297
95	P	L	0.5195
96	F	L	0.0000
97	T	L	0.0533
98	F	L	0.2319
99	G	L	0.0000
100	S	L	-0.1377
101	G	L	0.0000
102	T	L	0.0000
103	K	L	-0.6253
104	L	L	0.0000
105	E	L	-0.8932
106	I	L	-0.5551
106A	K	L	-1.3849