Project name: 5cma:B
Status: done
submitted: 2019-03-20 15:49:44, status changed: 2019-03-20 17:24:07
Settings
|
Chain sequence(s)
|
B: QVQLQQSGAELVKPGASVKLSCKASGYTFTNYDINWVRQRPEQGLEWIGWIFPGDGSTQYNEKFKGKATLTTDTSSSTAYMQLSRLTSEDSAVYFCARQTTATWFAYWGQGTLVTVSAASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6023
-
Maximal score value
-
2.5143
-
Average score
-
-0.6163
-
Total score value
-
-131.2649
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
B |
-1.4426 |
|
| 2 |
V |
B |
-0.6958 |
|
| 3 |
Q |
B |
-1.6268 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
Q |
B |
-1.8959 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-1.0759 |
|
| 8 |
G |
B |
-1.1368 |
|
| 9 |
A |
B |
-0.6671 |
|
| 10 |
E |
B |
-0.9398 |
|
| 11 |
L |
B |
-0.4258 |
|
| 12 |
V |
B |
0.0000 |
|
| 13 |
K |
B |
-2.0418 |
|
| 14 |
P |
B |
-1.7213 |
|
| 15 |
G |
B |
-1.7027 |
|
| 16 |
A |
B |
-1.4112 |
|
| 17 |
S |
B |
-1.5859 |
|
| 18 |
V |
B |
0.0000 |
|
| 19 |
K |
B |
-2.0517 |
|
| 20 |
L |
B |
0.0000 |
|
| 21 |
S |
B |
-0.9412 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
K |
B |
-1.7250 |
|
| 24 |
A |
B |
0.0000 |
|
| 25 |
S |
B |
-1.0722 |
|
| 26 |
G |
B |
-0.9574 |
|
| 27 |
Y |
B |
-0.4579 |
|
| 28 |
T |
B |
-0.3361 |
|
| 29 |
F |
B |
0.0000 |
|
| 30 |
T |
B |
-1.1266 |
|
| 31 |
N |
B |
-1.4064 |
|
| 32 |
Y |
B |
-0.3950 |
|
| 33 |
D |
B |
-0.2358 |
|
| 34 |
I |
B |
0.0000 |
|
| 35 |
N |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.9204 |
|
| 40 |
R |
B |
-1.9357 |
|
| 41 |
P |
B |
-2.0298 |
|
| 42 |
E |
B |
-2.7622 |
|
| 43 |
Q |
B |
-2.3082 |
|
| 44 |
G |
B |
-1.1043 |
|
| 45 |
L |
B |
0.5181 |
|
| 46 |
E |
B |
-0.5240 |
|
| 47 |
W |
B |
-0.2263 |
|
| 48 |
I |
B |
0.0000 |
|
| 49 |
G |
B |
0.0000 |
|
| 50 |
W |
B |
-0.0226 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
F |
B |
-0.5443 |
|
| 53 |
P |
B |
0.0000 |
|
| 54 |
G |
B |
-1.6623 |
|
| 55 |
D |
B |
-2.1602 |
|
| 56 |
G |
B |
-1.2829 |
|
| 57 |
S |
B |
-0.8667 |
|
| 58 |
T |
B |
-0.6328 |
|
| 59 |
Q |
B |
-1.3143 |
|
| 60 |
Y |
B |
-1.6279 |
|
| 61 |
N |
B |
-2.2668 |
|
| 62 |
E |
B |
-3.6023 |
|
| 63 |
K |
B |
-3.2942 |
|
| 64 |
F |
B |
0.0000 |
|
| 65 |
K |
B |
-3.3013 |
|
| 66 |
G |
B |
-2.2956 |
|
| 67 |
K |
B |
-2.1018 |
|
| 68 |
A |
B |
0.0000 |
|
| 69 |
T |
B |
-0.9791 |
|
| 70 |
L |
B |
0.0000 |
|
| 71 |
T |
B |
-0.2944 |
|
| 72 |
T |
B |
-1.0069 |
|
| 73 |
D |
B |
-1.4897 |
|
| 74 |
T |
B |
-1.1358 |
|
| 75 |
S |
B |
-0.7221 |
|
| 76 |
S |
B |
-0.8819 |
|
| 77 |
S |
B |
-0.9028 |
|
| 78 |
T |
B |
0.0000 |
|
| 79 |
A |
B |
0.0000 |
|
| 80 |
Y |
B |
-0.7272 |
|
| 81 |
M |
B |
0.0000 |
|
| 82 |
Q |
B |
-1.4195 |
|
| 83 |
L |
B |
0.0000 |
|
| 84 |
S |
B |
-1.8278 |
|
| 85 |
R |
B |
-2.3993 |
|
| 86 |
L |
B |
0.0000 |
|
| 87 |
T |
B |
-1.6100 |
|
| 88 |
S |
B |
-1.4207 |
|
| 89 |
E |
B |
-2.1056 |
|
| 90 |
D |
B |
0.0000 |
|
| 91 |
S |
B |
-0.8763 |
|
| 92 |
A |
B |
0.0000 |
|
| 93 |
V |
B |
0.2504 |
|
| 94 |
Y |
B |
0.0000 |
|
| 95 |
F |
B |
0.3843 |
|
| 96 |
C |
B |
0.0000 |
|
| 97 |
A |
B |
0.0000 |
|
| 98 |
R |
B |
0.0000 |
|
| 99 |
Q |
B |
0.3063 |
|
| 100 |
T |
B |
0.0861 |
|
| 101 |
T |
B |
0.0018 |
|
| 102 |
A |
B |
0.3081 |
|
| 103 |
T |
B |
0.4711 |
|
| 104 |
W |
B |
1.2395 |
|
| 105 |
F |
B |
1.0885 |
|
| 106 |
A |
B |
0.8065 |
|
| 107 |
Y |
B |
0.7571 |
|
| 108 |
W |
B |
0.3372 |
|
| 109 |
G |
B |
-0.8380 |
|
| 110 |
Q |
B |
-1.3114 |
|
| 111 |
G |
B |
-0.5242 |
|
| 112 |
T |
B |
0.0000 |
|
| 113 |
L |
B |
-0.0304 |
|
| 114 |
V |
B |
0.0000 |
|
| 115 |
T |
B |
-0.5276 |
|
| 116 |
V |
B |
0.0000 |
|
| 117 |
S |
B |
-0.6671 |
|
| 118 |
A |
B |
-0.6428 |
|
| 119 |
A |
B |
-0.4429 |
|
| 120 |
S |
B |
-0.6235 |
|
| 121 |
T |
B |
-0.7602 |
|
| 122 |
K |
B |
-1.2947 |
|
| 123 |
G |
B |
-1.4612 |
|
| 124 |
P |
B |
-0.5710 |
|
| 125 |
S |
B |
-0.0453 |
|
| 126 |
V |
B |
0.0000 |
|
| 127 |
F |
B |
1.1453 |
|
| 128 |
P |
B |
0.2406 |
|
| 129 |
L |
B |
0.8419 |
|
| 130 |
A |
B |
-0.4154 |
|
| 131 |
P |
B |
-0.6494 |
|
| 139 |
G |
B |
-0.6419 |
|
| 140 |
T |
B |
-0.4798 |
|
| 141 |
A |
B |
-0.3154 |
|
| 142 |
A |
B |
0.0907 |
|
| 143 |
L |
B |
0.0000 |
|
| 144 |
G |
B |
0.0000 |
|
| 145 |
C |
B |
0.0000 |
|
| 146 |
L |
B |
0.7927 |
|
| 147 |
V |
B |
0.0000 |
|
| 148 |
K |
B |
-0.1739 |
|
| 149 |
D |
B |
-0.5535 |
|
| 150 |
Y |
B |
0.0000 |
|
| 151 |
F |
B |
0.0000 |
|
| 152 |
P |
B |
0.0000 |
|
| 153 |
E |
B |
-0.3470 |
|
| 154 |
P |
B |
-0.6255 |
|
| 155 |
V |
B |
-0.5880 |
|
| 156 |
T |
B |
-0.5358 |
|
| 157 |
V |
B |
-0.1875 |
|
| 158 |
S |
B |
-0.4475 |
|
| 159 |
W |
B |
0.0000 |
|
| 160 |
N |
B |
-0.8511 |
|
| 161 |
S |
B |
-0.6744 |
|
| 162 |
G |
B |
-0.5361 |
|
| 163 |
A |
B |
-0.2352 |
|
| 164 |
L |
B |
-0.0234 |
|
| 165 |
T |
B |
-0.3160 |
|
| 166 |
S |
B |
-0.3812 |
|
| 167 |
G |
B |
-0.4954 |
|
| 168 |
V |
B |
-0.0998 |
|
| 169 |
H |
B |
-0.5587 |
|
| 170 |
T |
B |
0.0444 |
|
| 171 |
F |
B |
0.7420 |
|
| 172 |
P |
B |
0.6275 |
|
| 173 |
A |
B |
1.2274 |
|
| 174 |
V |
B |
2.5143 |
|
| 175 |
L |
B |
2.1900 |
|
| 176 |
Q |
B |
0.7445 |
|
| 177 |
S |
B |
0.0852 |
|
| 178 |
S |
B |
-0.2262 |
|
| 179 |
G |
B |
-0.0262 |
|
| 180 |
L |
B |
0.2991 |
|
| 181 |
Y |
B |
0.8092 |
|
| 182 |
S |
B |
0.7069 |
|
| 183 |
L |
B |
0.0000 |
|
| 184 |
S |
B |
0.5872 |
|
| 185 |
S |
B |
0.0000 |
|
| 186 |
V |
B |
0.3898 |
|
| 187 |
V |
B |
0.0000 |
|
| 188 |
T |
B |
-0.2538 |
|
| 189 |
V |
B |
0.0000 |
|
| 190 |
P |
B |
-0.5039 |
|
| 191 |
S |
B |
-0.5573 |
|
| 192 |
S |
B |
-0.6538 |
|
| 193 |
S |
B |
-0.6910 |
|
| 194 |
L |
B |
-0.8730 |
|
| 195 |
G |
B |
-1.0166 |
|
| 196 |
T |
B |
-0.8340 |
|
| 197 |
Q |
B |
-1.1953 |
|
| 198 |
T |
B |
-1.2264 |
|
| 199 |
Y |
B |
0.0000 |
|
| 200 |
I |
B |
-1.4499 |
|
| 201 |
C |
B |
0.0000 |
|
| 202 |
N |
B |
-1.5000 |
|
| 203 |
V |
B |
0.0000 |
|
| 204 |
N |
B |
-1.8625 |
|
| 205 |
H |
B |
0.0000 |
|
| 206 |
K |
B |
-2.9149 |
|
| 207 |
P |
B |
-1.7236 |
|
| 208 |
S |
B |
-1.8875 |
|
| 209 |
N |
B |
-2.6291 |
|
| 210 |
T |
B |
-2.0995 |
|
| 211 |
K |
B |
-2.7194 |
|
| 212 |
V |
B |
-1.7623 |
|
| 213 |
D |
B |
-2.6631 |
|
| 214 |
K |
B |
-2.2485 |
|
| 215 |
R |
B |
-2.6314 |
|
| 216 |
V |
B |
0.0000 |
|
| 217 |
E |
B |
-2.7319 |
|
| 218 |
P |
B |
-1.8539 |
|
| 219 |
K |
B |
-2.3618 |
|
| 220 |
S |
B |
-1.2689 |
|