Project name: 1s78:C
Status: done
submitted: 2019-03-20 20:05:43, status changed: 2019-03-20 20:18:09
Settings
|
Chain sequence(s)
|
C: DIQMTQSPSSLSASVGDRVTITCKASQDVSIGVAWYQQKPGKAPKLLIYSASYRYTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYYIYPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.9389
-
Maximal score value
-
2.4659
-
Average score
-
-0.7244
-
Total score value
-
-155.0128
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
C |
-1.7780 |
|
| 2 |
I |
C |
0.0000 |
|
| 3 |
Q |
C |
-1.6079 |
|
| 4 |
M |
C |
0.0000 |
|
| 5 |
T |
C |
-0.9905 |
|
| 6 |
Q |
C |
0.0000 |
|
| 7 |
S |
C |
-0.6912 |
|
| 8 |
P |
C |
-0.4983 |
|
| 9 |
S |
C |
-0.8898 |
|
| 10 |
S |
C |
-0.8585 |
|
| 11 |
L |
C |
-0.4664 |
|
| 12 |
S |
C |
-0.6616 |
|
| 13 |
A |
C |
0.0000 |
|
| 14 |
S |
C |
-0.5989 |
|
| 15 |
V |
C |
-0.0539 |
|
| 16 |
G |
C |
-0.8733 |
|
| 17 |
D |
C |
-1.6674 |
|
| 18 |
R |
C |
-2.3451 |
|
| 19 |
V |
C |
0.0000 |
|
| 20 |
T |
C |
-0.5925 |
|
| 21 |
I |
C |
0.0000 |
|
| 22 |
T |
C |
-0.7504 |
|
| 23 |
C |
C |
0.0000 |
|
| 24 |
K |
C |
-2.1808 |
|
| 25 |
A |
C |
0.0000 |
|
| 26 |
S |
C |
-2.0499 |
|
| 27 |
Q |
C |
-2.4616 |
|
| 28 |
D |
C |
-2.2865 |
|
| 29 |
V |
C |
0.0000 |
|
| 30 |
S |
C |
-0.1443 |
|
| 31 |
I |
C |
0.9449 |
|
| 32 |
G |
C |
0.0000 |
|
| 33 |
V |
C |
0.0000 |
|
| 34 |
A |
C |
0.0000 |
|
| 35 |
W |
C |
0.0000 |
|
| 36 |
Y |
C |
0.1460 |
|
| 37 |
Q |
C |
0.0000 |
|
| 38 |
Q |
C |
-1.4378 |
|
| 39 |
K |
C |
-1.9183 |
|
| 40 |
P |
C |
-1.5839 |
|
| 41 |
G |
C |
-1.5925 |
|
| 42 |
K |
C |
-2.4210 |
|
| 43 |
A |
C |
-1.4365 |
|
| 44 |
P |
C |
-1.3179 |
|
| 45 |
K |
C |
-1.3627 |
|
| 46 |
L |
C |
-0.0798 |
|
| 47 |
L |
C |
0.0000 |
|
| 48 |
I |
C |
0.0000 |
|
| 49 |
Y |
C |
1.2663 |
|
| 50 |
S |
C |
1.0512 |
|
| 51 |
A |
C |
0.0000 |
|
| 52 |
S |
C |
0.4315 |
|
| 53 |
Y |
C |
0.9651 |
|
| 54 |
R |
C |
-0.3075 |
|
| 55 |
Y |
C |
0.6372 |
|
| 56 |
T |
C |
0.0556 |
|
| 57 |
G |
C |
-0.5384 |
|
| 58 |
V |
C |
0.0000 |
|
| 59 |
P |
C |
-0.5779 |
|
| 60 |
S |
C |
-0.8033 |
|
| 61 |
R |
C |
-1.0170 |
|
| 62 |
F |
C |
0.0000 |
|
| 63 |
S |
C |
-0.4680 |
|
| 64 |
G |
C |
0.0000 |
|
| 65 |
S |
C |
-0.4220 |
|
| 66 |
G |
C |
-0.8540 |
|
| 67 |
S |
C |
-0.8637 |
|
| 68 |
G |
C |
-1.4647 |
|
| 69 |
T |
C |
-2.0955 |
|
| 70 |
D |
C |
-2.7049 |
|
| 71 |
F |
C |
0.0000 |
|
| 72 |
T |
C |
-0.7868 |
|
| 73 |
L |
C |
0.0000 |
|
| 74 |
T |
C |
-0.6126 |
|
| 75 |
I |
C |
0.0000 |
|
| 76 |
S |
C |
-1.2994 |
|
| 77 |
S |
C |
-1.3031 |
|
| 78 |
L |
C |
0.0000 |
|
| 79 |
Q |
C |
-1.2792 |
|
| 80 |
P |
C |
-0.9980 |
|
| 81 |
E |
C |
-1.9360 |
|
| 82 |
D |
C |
0.0000 |
|
| 83 |
F |
C |
-0.6761 |
|
| 84 |
A |
C |
0.0000 |
|
| 85 |
T |
C |
0.0000 |
|
| 86 |
Y |
C |
0.0000 |
|
| 87 |
Y |
C |
0.0598 |
|
| 88 |
C |
C |
0.0000 |
|
| 89 |
Q |
C |
1.0924 |
|
| 90 |
Q |
C |
0.0000 |
|
| 91 |
Y |
C |
2.4659 |
|
| 92 |
Y |
C |
2.2961 |
|
| 93 |
I |
C |
1.8843 |
|
| 94 |
Y |
C |
2.1426 |
|
| 95 |
P |
C |
1.4069 |
|
| 96 |
Y |
C |
2.3184 |
|
| 97 |
T |
C |
1.3023 |
|
| 98 |
F |
C |
1.5650 |
|
| 99 |
G |
C |
0.0000 |
|
| 100 |
Q |
C |
-0.9417 |
|
| 101 |
G |
C |
0.0000 |
|
| 102 |
T |
C |
0.0000 |
|
| 103 |
K |
C |
-1.5232 |
|
| 104 |
V |
C |
0.0000 |
|
| 105 |
E |
C |
-0.8166 |
|
| 106 |
I |
C |
-0.4699 |
|
| 107 |
K |
C |
-1.0708 |
|
| 108 |
R |
C |
-0.6569 |
|
| 109 |
T |
C |
0.2579 |
|
| 110 |
V |
C |
1.2164 |
|
| 111 |
A |
C |
0.4336 |
|
| 112 |
A |
C |
-0.1044 |
|
| 113 |
P |
C |
0.0000 |
|
| 114 |
S |
C |
-0.2604 |
|
| 115 |
V |
C |
0.0000 |
|
| 116 |
F |
C |
1.1682 |
|
| 117 |
I |
C |
1.3159 |
|
| 118 |
F |
C |
1.8817 |
|
| 119 |
P |
C |
0.2930 |
|
| 120 |
P |
C |
-0.6438 |
|
| 121 |
S |
C |
-1.8411 |
|
| 122 |
D |
C |
-3.2203 |
|
| 123 |
E |
C |
-3.5292 |
|
| 124 |
Q |
C |
-2.9708 |
|
| 125 |
L |
C |
-2.2801 |
|
| 126 |
K |
C |
-2.8687 |
|
| 127 |
S |
C |
-1.8268 |
|
| 128 |
G |
C |
-1.2481 |
|
| 129 |
T |
C |
-1.1917 |
|
| 130 |
A |
C |
0.0000 |
|
| 131 |
S |
C |
-0.0133 |
|
| 132 |
V |
C |
0.0000 |
|
| 133 |
V |
C |
1.0948 |
|
| 134 |
C |
C |
0.0000 |
|
| 135 |
L |
C |
0.8561 |
|
| 136 |
L |
C |
0.0000 |
|
| 137 |
N |
C |
-0.6238 |
|
| 138 |
N |
C |
-1.3209 |
|
| 139 |
F |
C |
0.0000 |
|
| 140 |
Y |
C |
0.0000 |
|
| 141 |
P |
C |
-1.7188 |
|
| 142 |
R |
C |
-3.0373 |
|
| 143 |
E |
C |
-3.3324 |
|
| 144 |
A |
C |
-2.4109 |
|
| 145 |
K |
C |
-2.6123 |
|
| 146 |
V |
C |
-1.4717 |
|
| 147 |
Q |
C |
-1.4144 |
|
| 148 |
W |
C |
0.0000 |
|
| 149 |
K |
C |
-1.0280 |
|
| 150 |
V |
C |
-1.1527 |
|
| 151 |
D |
C |
-2.1577 |
|
| 152 |
N |
C |
-1.7345 |
|
| 153 |
A |
C |
-0.5957 |
|
| 154 |
L |
C |
-0.0414 |
|
| 155 |
Q |
C |
-0.9340 |
|
| 156 |
S |
C |
-0.9624 |
|
| 157 |
G |
C |
-1.3018 |
|
| 158 |
N |
C |
-1.2163 |
|
| 159 |
S |
C |
-1.6986 |
|
| 160 |
Q |
C |
-2.3884 |
|
| 161 |
E |
C |
-2.4036 |
|
| 162 |
S |
C |
-1.1392 |
|
| 163 |
V |
C |
-0.7727 |
|
| 164 |
T |
C |
-1.3300 |
|
| 165 |
E |
C |
-2.2286 |
|
| 166 |
Q |
C |
-2.3678 |
|
| 167 |
D |
C |
-2.3773 |
|
| 168 |
S |
C |
-1.8796 |
|
| 169 |
K |
C |
-2.3577 |
|
| 170 |
D |
C |
-1.8840 |
|
| 171 |
S |
C |
-1.9768 |
|
| 172 |
T |
C |
0.0000 |
|
| 173 |
Y |
C |
0.0000 |
|
| 174 |
S |
C |
-1.0587 |
|
| 175 |
L |
C |
0.0000 |
|
| 176 |
S |
C |
-0.4504 |
|
| 177 |
S |
C |
0.0000 |
|
| 178 |
T |
C |
-0.5972 |
|
| 179 |
L |
C |
0.0000 |
|
| 180 |
T |
C |
-0.3856 |
|
| 181 |
L |
C |
-0.5584 |
|
| 182 |
S |
C |
-1.2814 |
|
| 183 |
K |
C |
-2.4166 |
|
| 184 |
A |
C |
-2.1426 |
|
| 185 |
D |
C |
-3.1656 |
|
| 186 |
Y |
C |
0.0000 |
|
| 187 |
E |
C |
-3.9389 |
|
| 188 |
K |
C |
-3.8388 |
|
| 189 |
H |
C |
-3.2530 |
|
| 190 |
K |
C |
-3.1313 |
|
| 191 |
V |
C |
-1.5106 |
|
| 192 |
Y |
C |
0.0000 |
|
| 193 |
A |
C |
-0.5857 |
|
| 194 |
C |
C |
0.0000 |
|
| 195 |
E |
C |
-1.1873 |
|
| 196 |
V |
C |
0.0000 |
|
| 197 |
T |
C |
-1.2971 |
|
| 198 |
H |
C |
0.0000 |
|
| 199 |
Q |
C |
-1.7762 |
|
| 200 |
G |
C |
-0.5018 |
|
| 201 |
L |
C |
-0.0971 |
|
| 202 |
S |
C |
-0.3940 |
|
| 203 |
S |
C |
-0.3627 |
|
| 204 |
P |
C |
-0.4857 |
|
| 205 |
V |
C |
0.0149 |
|
| 206 |
T |
C |
-0.4371 |
|
| 207 |
K |
C |
-0.8131 |
|
| 208 |
S |
C |
-0.3436 |
|
| 209 |
F |
C |
0.0000 |
|
| 210 |
N |
C |
-1.7755 |
|
| 211 |
R |
C |
-2.6960 |
|
| 212 |
G |
C |
-2.1910 |
|
| 213 |
E |
C |
-2.1866 |
|
| 214 |
C |
C |
-0.7628 |
|