Project name: 434353ae86fb3e

Chain sequence(s)	A: PSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDAD; B: GSPGYPNGLLSGDEDFSSIADMDFSALLSQISS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -5.0861
• Maximal score value: 1.5458
• Average score: -1.0758
• Total score value: -159.222

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	P	A	-0.4749
2	S	A	-0.5182
3	H	A	-0.6787
4	S	A	-0.2308
5	G	A	-0.2428
6	A	A	-0.0480
7	A	A	0.0000
8	I	A	-0.0995
9	F	A	-0.7360
10	E	A	-2.8689
11	K	A	-2.3017
12	V	A	-0.7108
13	S	A	-0.5054
14	G	A	0.0000
15	I	A	0.4886
16	I	A	0.0000
17	A	A	-0.2954
18	I	A	-0.3793
19	N	A	-0.8479
20	E	A	-1.2599
21	D	A	-1.5896
22	V	A	-0.0993
23	S	A	-0.2177
24	P	A	-0.2830
25	A	A	0.0000
26	E	A	-0.3107
27	L	A	0.0000
28	T	A	0.0259
29	W	A	0.0000
30	R	A	-0.9221
31	S	A	0.0000
32	T	A	-1.2102
33	D	A	-2.3919
34	G	A	-1.9081
35	D	A	-2.4823
36	K	A	-1.3223
37	V	A	0.2970
38	H	A	0.0838
39	T	A	0.0070
40	V	A	0.0000
41	V	A	0.0665
42	L	A	0.0000
43	S	A	-0.7987
44	T	A	-0.6948
45	I	A	0.0000
46	D	A	-2.1526
47	K	A	-2.4164
48	L	A	-1.2385
49	Q	A	-0.5659
50	A	A	-0.2857
51	T	A	0.0000
52	P	A	-0.3402
53	A	A	-0.6387
54	S	A	-0.6312
55	S	A	0.0000
56	E	A	-2.0162
57	K	A	-1.5054
58	M	A	-0.7387
59	M	A	-0.3675
60	L	A	0.0000
61	R	A	0.0000
62	L	A	0.0000
63	I	A	0.0000
64	G	A	-2.0961
65	K	A	-2.8672
66	V	A	-2.2087
67	D	A	-3.1622
68	E	A	-4.0849
69	S	A	-2.9591
70	K	A	-4.0745
71	K	A	-4.5981
72	R	A	-4.6947
73	K	A	-5.0861
74	D	A	-4.0650
75	N	A	-3.3140
76	E	A	-3.7529
77	G	A	-3.6407
78	N	A	-4.0016
79	E	A	-3.9169
80	V	A	-2.2414
81	V	A	-2.7336
82	P	A	-2.3781
83	K	A	-2.4716
84	P	A	-2.4939
85	Q	A	-2.2488
86	R	A	-2.2445
87	H	A	-1.0011
88	M	A	-0.3989
89	F	A	0.0000
90	S	A	-0.4745
91	F	A	0.0000
92	N	A	-1.7565
93	N	A	-2.0292
94	R	A	-1.5378
95	T	A	-1.2589
96	V	A	-1.2016
97	M	A	0.0000
98	D	A	-2.3144
99	N	A	-1.5588
100	I	A	0.0000
101	K	A	-1.7164
102	M	A	-1.3007
103	T	A	0.0000
104	L	A	0.0000
105	Q	A	-2.3740
106	Q	A	-2.1528
107	I	A	0.0000
108	I	A	0.0000
109	S	A	-2.7858
110	R	A	-3.4303
111	Y	A	-2.2817
112	K	A	-3.4675
113	D	A	-3.4829
114	A	A	-2.4724
115	D	A	-2.6863
519	G	B	-0.6736
520	S	B	-0.6699
521	P	B	-0.4469
522	G	B	-0.2496
523	Y	B	0.6061
524	P	B	-0.2685
525	N	B	-0.5894
526	G	B	0.1428
527	L	B	1.2688
528	L	B	1.5458
529	S	B	-0.0757
530	G	B	-1.1467
531	D	B	-3.3167
532	E	B	-3.4959
533	D	B	-2.1585
534	F	B	-0.3435
535	S	B	-1.0027
536	S	B	-0.0731
537	I	B	1.5175
538	A	B	0.5468
539	D	B	0.2635
540	M	B	0.8284
541	D	B	-0.3014
542	F	B	0.0000
543	S	B	-0.1079
544	A	B	0.2354
545	L	B	0.2148
546	L	B	1.1478
547	S	B	0.5213
548	Q	B	0.1756
549	I	B	1.4835
550	S	B	0.4231
551	S	B	0.1510