Project name: 5gzo:D
Status: done
submitted: 2019-03-21 13:16:56, status changed: 2019-03-21 13:28:05
Settings
|
Chain sequence(s)
|
D: DIVMTQSPSSLSASVGDRVTITCRASQGIRNDLGWYQQKPGKAPKRLIYAASSLQSGVPSRFSGSGSGTEFTLTISSLQPEDFATYYCLQHNSYPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-3.937
-
Maximal score value
-
1.5357
-
Average score
-
-0.9234
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Total score value
-
-196.6786
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
D |
-1.6146 |
|
| 2 |
I |
D |
0.0000 |
|
| 3 |
V |
D |
0.7158 |
|
| 4 |
M |
D |
0.0000 |
|
| 5 |
T |
D |
-0.5371 |
|
| 6 |
Q |
D |
0.0000 |
|
| 7 |
S |
D |
-0.7281 |
|
| 8 |
P |
D |
-0.5747 |
|
| 9 |
S |
D |
-0.8340 |
|
| 10 |
S |
D |
-0.7237 |
|
| 11 |
L |
D |
-0.4317 |
|
| 12 |
S |
D |
-0.8534 |
|
| 13 |
A |
D |
-1.1207 |
|
| 14 |
S |
D |
-1.0590 |
|
| 15 |
V |
D |
-0.1152 |
|
| 16 |
G |
D |
-0.8162 |
|
| 17 |
D |
D |
-1.8762 |
|
| 18 |
R |
D |
-2.3450 |
|
| 19 |
V |
D |
0.0000 |
|
| 20 |
T |
D |
-0.6035 |
|
| 21 |
I |
D |
0.0000 |
|
| 22 |
T |
D |
-0.9409 |
|
| 23 |
C |
D |
0.0000 |
|
| 24 |
R |
D |
-2.4164 |
|
| 25 |
A |
D |
0.0000 |
|
| 26 |
S |
D |
-1.1115 |
|
| 27 |
Q |
D |
-2.1675 |
|
| 28 |
G |
D |
-2.4421 |
|
| 29 |
I |
D |
0.0000 |
|
| 30 |
R |
D |
-3.2752 |
|
| 31 |
N |
D |
-2.4650 |
|
| 32 |
D |
D |
-1.9053 |
|
| 33 |
L |
D |
0.0000 |
|
| 34 |
G |
D |
0.0000 |
|
| 35 |
W |
D |
0.0000 |
|
| 36 |
Y |
D |
-0.9616 |
|
| 37 |
Q |
D |
-1.5726 |
|
| 38 |
Q |
D |
-1.7859 |
|
| 39 |
K |
D |
-1.8538 |
|
| 40 |
P |
D |
-1.5123 |
|
| 41 |
G |
D |
-1.6812 |
|
| 42 |
K |
D |
-2.3801 |
|
| 43 |
A |
D |
-1.7160 |
|
| 44 |
P |
D |
-2.0066 |
|
| 45 |
K |
D |
-2.9486 |
|
| 46 |
R |
D |
-2.6020 |
|
| 47 |
L |
D |
0.0000 |
|
| 48 |
I |
D |
0.0000 |
|
| 49 |
Y |
D |
0.0194 |
|
| 50 |
A |
D |
-0.5443 |
|
| 51 |
A |
D |
0.0000 |
|
| 52 |
S |
D |
-0.4080 |
|
| 53 |
S |
D |
0.1000 |
|
| 54 |
L |
D |
0.0854 |
|
| 55 |
Q |
D |
-0.5055 |
|
| 56 |
S |
D |
-0.6557 |
|
| 57 |
G |
D |
-0.7237 |
|
| 58 |
V |
D |
-0.6780 |
|
| 59 |
P |
D |
-0.3525 |
|
| 60 |
S |
D |
-0.4660 |
|
| 61 |
R |
D |
-0.8009 |
|
| 62 |
F |
D |
0.0000 |
|
| 63 |
S |
D |
-0.3819 |
|
| 64 |
G |
D |
-0.2129 |
|
| 65 |
S |
D |
-0.8755 |
|
| 66 |
G |
D |
-1.4372 |
|
| 67 |
S |
D |
-2.0151 |
|
| 68 |
G |
D |
-2.4904 |
|
| 69 |
T |
D |
-2.6100 |
|
| 70 |
E |
D |
-3.0596 |
|
| 71 |
F |
D |
0.0000 |
|
| 72 |
T |
D |
-0.8914 |
|
| 73 |
L |
D |
0.0000 |
|
| 74 |
T |
D |
-0.6401 |
|
| 75 |
I |
D |
0.0000 |
|
| 76 |
S |
D |
-1.4792 |
|
| 77 |
S |
D |
-1.2008 |
|
| 78 |
L |
D |
0.0000 |
|
| 79 |
Q |
D |
-0.6804 |
|
| 80 |
P |
D |
-1.5026 |
|
| 81 |
E |
D |
-1.2822 |
|
| 82 |
D |
D |
0.0000 |
|
| 83 |
F |
D |
0.0000 |
|
| 84 |
A |
D |
0.0000 |
|
| 85 |
T |
D |
-0.9006 |
|
| 86 |
Y |
D |
0.0000 |
|
| 87 |
Y |
D |
-0.2386 |
|
| 88 |
C |
D |
0.0000 |
|
| 89 |
L |
D |
0.0000 |
|
| 90 |
Q |
D |
0.0000 |
|
| 91 |
H |
D |
-1.5084 |
|
| 92 |
N |
D |
-1.8145 |
|
| 93 |
S |
D |
-0.8985 |
|
| 94 |
Y |
D |
0.0822 |
|
| 95 |
P |
D |
-0.7856 |
|
| 96 |
R |
D |
-1.5089 |
|
| 97 |
T |
D |
-0.1718 |
|
| 98 |
F |
D |
1.1922 |
|
| 99 |
G |
D |
0.0000 |
|
| 100 |
Q |
D |
-0.7666 |
|
| 101 |
G |
D |
-0.6540 |
|
| 102 |
T |
D |
0.0000 |
|
| 103 |
K |
D |
-1.4736 |
|
| 104 |
V |
D |
0.0000 |
|
| 105 |
E |
D |
-1.1754 |
|
| 106 |
I |
D |
0.0000 |
|
| 107 |
K |
D |
-1.7840 |
|
| 108 |
R |
D |
-0.9787 |
|
| 109 |
T |
D |
-0.1671 |
|
| 110 |
V |
D |
0.3077 |
|
| 111 |
A |
D |
0.1355 |
|
| 112 |
A |
D |
-0.2087 |
|
| 113 |
P |
D |
0.0000 |
|
| 114 |
S |
D |
-0.0624 |
|
| 115 |
V |
D |
0.0000 |
|
| 116 |
F |
D |
1.5357 |
|
| 117 |
I |
D |
1.3712 |
|
| 118 |
F |
D |
1.4774 |
|
| 119 |
P |
D |
-0.2163 |
|
| 120 |
P |
D |
-0.7172 |
|
| 121 |
S |
D |
-1.8898 |
|
| 122 |
D |
D |
-3.3888 |
|
| 123 |
E |
D |
-3.5804 |
|
| 124 |
Q |
D |
-2.8166 |
|
| 125 |
L |
D |
-2.6979 |
|
| 126 |
K |
D |
-3.1223 |
|
| 127 |
S |
D |
-1.9550 |
|
| 128 |
G |
D |
-1.5337 |
|
| 129 |
T |
D |
-1.4098 |
|
| 130 |
A |
D |
0.0000 |
|
| 131 |
S |
D |
-0.0366 |
|
| 132 |
V |
D |
0.0000 |
|
| 133 |
V |
D |
1.0086 |
|
| 134 |
C |
D |
0.0000 |
|
| 135 |
L |
D |
0.7946 |
|
| 136 |
L |
D |
0.0000 |
|
| 137 |
N |
D |
-0.5675 |
|
| 138 |
N |
D |
-1.2383 |
|
| 139 |
F |
D |
0.0000 |
|
| 140 |
Y |
D |
-1.0044 |
|
| 141 |
P |
D |
-1.4559 |
|
| 142 |
R |
D |
-2.0152 |
|
| 143 |
E |
D |
-2.8552 |
|
| 144 |
A |
D |
-2.0548 |
|
| 145 |
K |
D |
-2.0125 |
|
| 146 |
V |
D |
-1.1876 |
|
| 147 |
Q |
D |
-0.8336 |
|
| 148 |
W |
D |
0.0000 |
|
| 149 |
K |
D |
-0.7853 |
|
| 150 |
V |
D |
0.0000 |
|
| 151 |
D |
D |
-1.7601 |
|
| 152 |
N |
D |
-1.3670 |
|
| 153 |
A |
D |
-0.2965 |
|
| 154 |
L |
D |
0.6650 |
|
| 155 |
Q |
D |
-0.1644 |
|
| 156 |
S |
D |
-0.6193 |
|
| 157 |
G |
D |
-1.0254 |
|
| 158 |
N |
D |
-1.0073 |
|
| 159 |
S |
D |
-1.4941 |
|
| 160 |
Q |
D |
-2.3295 |
|
| 161 |
E |
D |
-2.3854 |
|
| 162 |
S |
D |
-1.0775 |
|
| 163 |
V |
D |
-0.5335 |
|
| 164 |
T |
D |
-1.0408 |
|
| 165 |
E |
D |
-2.1529 |
|
| 166 |
Q |
D |
0.0000 |
|
| 167 |
D |
D |
-2.6970 |
|
| 168 |
S |
D |
-2.2487 |
|
| 169 |
K |
D |
-2.6521 |
|
| 170 |
D |
D |
-2.1766 |
|
| 171 |
S |
D |
0.0000 |
|
| 172 |
T |
D |
0.0000 |
|
| 173 |
Y |
D |
0.0000 |
|
| 174 |
S |
D |
-0.9416 |
|
| 175 |
L |
D |
0.0000 |
|
| 176 |
S |
D |
-0.3470 |
|
| 177 |
S |
D |
0.0000 |
|
| 178 |
T |
D |
-0.6703 |
|
| 179 |
L |
D |
0.0000 |
|
| 180 |
T |
D |
-0.6052 |
|
| 181 |
L |
D |
-0.8806 |
|
| 182 |
S |
D |
-1.2625 |
|
| 183 |
K |
D |
-2.3120 |
|
| 184 |
A |
D |
-2.2325 |
|
| 185 |
D |
D |
-3.1836 |
|
| 186 |
Y |
D |
0.0000 |
|
| 187 |
E |
D |
-3.9370 |
|
| 188 |
K |
D |
-3.8036 |
|
| 189 |
H |
D |
-3.2470 |
|
| 190 |
K |
D |
-3.0521 |
|
| 191 |
V |
D |
-1.4965 |
|
| 192 |
Y |
D |
0.0000 |
|
| 193 |
A |
D |
-0.8001 |
|
| 194 |
C |
D |
0.0000 |
|
| 195 |
E |
D |
-1.0770 |
|
| 196 |
V |
D |
0.0000 |
|
| 197 |
T |
D |
-1.1699 |
|
| 198 |
H |
D |
0.0000 |
|
| 199 |
Q |
D |
-1.6457 |
|
| 200 |
G |
D |
-0.4241 |
|
| 201 |
L |
D |
-0.3546 |
|
| 202 |
S |
D |
-0.4659 |
|
| 203 |
S |
D |
-0.4091 |
|
| 204 |
P |
D |
-0.4846 |
|
| 205 |
V |
D |
-0.0103 |
|
| 206 |
T |
D |
-0.4463 |
|
| 207 |
K |
D |
-0.4035 |
|
| 208 |
S |
D |
-0.3247 |
|
| 209 |
F |
D |
-0.9535 |
|
| 210 |
N |
D |
-2.1559 |
|
| 211 |
R |
D |
-2.7135 |
|
| 212 |
G |
D |
-2.5117 |
|
| 213 |
E |
D |
-2.4756 |
|