Project name: 5xxy:L
Status: done
submitted: 2019-03-20 20:40:23, status changed: 2019-03-20 20:54:29
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRASQDVSTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYLYHPATFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7785
-
Maximal score value
-
2.1942
-
Average score
-
-0.7499
-
Total score value
-
-158.2354
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.3014 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-2.0613 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.3991 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.7723 |
|
| 8 |
P |
L |
-0.5888 |
|
| 9 |
S |
L |
-1.0244 |
|
| 10 |
S |
L |
-0.9727 |
|
| 11 |
L |
L |
-0.6674 |
|
| 12 |
S |
L |
-0.8105 |
|
| 13 |
A |
L |
-0.7141 |
|
| 14 |
S |
L |
-0.5237 |
|
| 15 |
V |
L |
0.5766 |
|
| 16 |
G |
L |
-0.3922 |
|
| 17 |
D |
L |
-1.3681 |
|
| 18 |
R |
L |
-2.1420 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6519 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.9697 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-3.1305 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-2.1457 |
|
| 27 |
Q |
L |
-2.2728 |
|
| 28 |
D |
L |
-2.7067 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
S |
L |
-0.9206 |
|
| 31 |
T |
L |
-0.4260 |
|
| 32 |
A |
L |
0.5102 |
|
| 33 |
V |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0727 |
|
| 37 |
Q |
L |
-0.9138 |
|
| 38 |
Q |
L |
-1.5138 |
|
| 39 |
K |
L |
-2.0068 |
|
| 40 |
P |
L |
-1.5529 |
|
| 41 |
G |
L |
-1.7055 |
|
| 42 |
K |
L |
-2.3356 |
|
| 43 |
A |
L |
-1.3450 |
|
| 44 |
P |
L |
-1.1816 |
|
| 45 |
K |
L |
-1.1955 |
|
| 46 |
L |
L |
0.2838 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
1.7391 |
|
| 50 |
S |
L |
0.8636 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
0.7787 |
|
| 53 |
F |
L |
2.1942 |
|
| 54 |
L |
L |
1.8734 |
|
| 55 |
Y |
L |
1.6089 |
|
| 56 |
S |
L |
0.3677 |
|
| 57 |
G |
L |
-0.2968 |
|
| 58 |
V |
L |
0.0000 |
|
| 59 |
P |
L |
-0.2756 |
|
| 60 |
S |
L |
-0.3507 |
|
| 61 |
R |
L |
-0.8553 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.0505 |
|
| 64 |
G |
L |
0.2242 |
|
| 65 |
S |
L |
-0.5082 |
|
| 66 |
G |
L |
-1.2366 |
|
| 67 |
S |
L |
-1.1818 |
|
| 68 |
G |
L |
-1.7858 |
|
| 69 |
T |
L |
-2.4651 |
|
| 70 |
D |
L |
-2.9531 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.9062 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6474 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3712 |
|
| 77 |
S |
L |
-0.9377 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.8607 |
|
| 80 |
P |
L |
-1.5018 |
|
| 81 |
E |
L |
-1.8836 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-1.3684 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
-0.2042 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.4083 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Y |
L |
1.1292 |
|
| 92 |
L |
L |
1.3069 |
|
| 93 |
Y |
L |
0.4541 |
|
| 94 |
H |
L |
-0.7362 |
|
| 95 |
P |
L |
-0.7447 |
|
| 96 |
A |
L |
-0.1393 |
|
| 97 |
T |
L |
-0.2207 |
|
| 98 |
F |
L |
0.4943 |
|
| 99 |
G |
L |
-0.6769 |
|
| 100 |
Q |
L |
-1.3464 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-2.0517 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.2758 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.0423 |
|
| 108 |
R |
L |
-0.7152 |
|
| 109 |
T |
L |
-0.0261 |
|
| 110 |
V |
L |
0.5113 |
|
| 111 |
A |
L |
0.1112 |
|
| 112 |
A |
L |
-0.1848 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1216 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.1282 |
|
| 117 |
I |
L |
1.3448 |
|
| 118 |
F |
L |
1.7580 |
|
| 119 |
P |
L |
0.0349 |
|
| 120 |
P |
L |
-0.6250 |
|
| 121 |
S |
L |
-1.8477 |
|
| 122 |
D |
L |
-3.3990 |
|
| 123 |
E |
L |
-3.6044 |
|
| 124 |
Q |
L |
-2.9154 |
|
| 125 |
L |
L |
-2.9292 |
|
| 126 |
K |
L |
-3.2082 |
|
| 127 |
S |
L |
-2.1422 |
|
| 128 |
G |
L |
-1.8426 |
|
| 129 |
T |
L |
-1.5177 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
-0.0466 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7762 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.6814 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.4833 |
|
| 138 |
N |
L |
-1.2995 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.5622 |
|
| 142 |
R |
L |
-2.5441 |
|
| 143 |
E |
L |
-3.0085 |
|
| 144 |
A |
L |
-2.1990 |
|
| 145 |
K |
L |
-2.2887 |
|
| 146 |
V |
L |
-1.1423 |
|
| 147 |
Q |
L |
-0.6720 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.6654 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.9196 |
|
| 152 |
N |
L |
-1.5390 |
|
| 153 |
A |
L |
-0.2699 |
|
| 154 |
L |
L |
0.6926 |
|
| 155 |
Q |
L |
-0.2291 |
|
| 156 |
S |
L |
-0.4403 |
|
| 157 |
G |
L |
-0.9870 |
|
| 158 |
N |
L |
-0.9580 |
|
| 159 |
S |
L |
-1.4840 |
|
| 160 |
Q |
L |
-2.2953 |
|
| 161 |
E |
L |
-2.2324 |
|
| 162 |
S |
L |
-0.9628 |
|
| 163 |
V |
L |
-0.4996 |
|
| 164 |
T |
L |
-0.9786 |
|
| 165 |
E |
L |
-2.1615 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.3302 |
|
| 168 |
S |
L |
-2.2896 |
|
| 169 |
K |
L |
-2.6785 |
|
| 170 |
D |
L |
-2.1023 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.7996 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.3455 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.4759 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.3820 |
|
| 181 |
L |
L |
-0.6843 |
|
| 182 |
S |
L |
-1.1271 |
|
| 183 |
K |
L |
-2.3143 |
|
| 184 |
A |
L |
-1.8152 |
|
| 185 |
D |
L |
-2.3463 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.7785 |
|
| 188 |
K |
L |
-3.5149 |
|
| 189 |
H |
L |
-3.2275 |
|
| 190 |
K |
L |
-3.6094 |
|
| 191 |
V |
L |
-2.2018 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.7266 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.1182 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7298 |
|
| 200 |
G |
L |
-0.4339 |
|
| 201 |
L |
L |
-0.1866 |
|
| 202 |
S |
L |
-0.4372 |
|
| 203 |
S |
L |
-0.3639 |
|
| 204 |
P |
L |
-0.5262 |
|
| 205 |
V |
L |
0.1631 |
|
| 206 |
T |
L |
-0.3718 |
|
| 207 |
K |
L |
-0.4573 |
|
| 208 |
S |
L |
-0.4648 |
|
| 209 |
F |
L |
-1.0638 |
|
| 210 |
N |
L |
-2.6459 |
|
| 211 |
R |
L |
-3.0938 |
|