| Chain sequence(s) |
A: MNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQIS B: DYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRN |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 225 | M | A | 0.3764 | |
| 226 | N | A | -0.6395 | |
| 227 | L | A | -0.1875 | |
| 228 | E | A | -0.8020 | |
| 229 | P | A | -0.3706 | |
| 230 | Y | A | 0.6679 | |
| 231 | F | A | 0.4235 | |
| 232 | E | A | -1.0644 | |
| 233 | S | A | -0.5166 | |
| 234 | F | A | -0.2348 | |
| 235 | I | A | -1.1712 | |
| 236 | N | A | -2.8425 | |
| 237 | N | A | -3.1035 | |
| 238 | L | A | 0.0000 | |
| 239 | R | A | -4.5308 | |
| 240 | R | A | -5.0665 | |
| 241 | R | A | -4.8143 | |
| 242 | V | A | 0.0000 | |
| 243 | D | A | -4.7314 | |
| 244 | Q | A | -4.1398 | |
| 245 | L | A | -3.5215 | |
| 246 | K | A | -3.4830 | |
| 247 | S | A | -2.7492 | |
| 248 | D | A | -2.7835 | |
| 249 | Q | A | -2.6682 | |
| 250 | S | A | -2.3003 | |
| 251 | R | A | -3.0112 | |
| 252 | L | A | -2.2300 | |
| 253 | D | A | -2.2172 | |
| 254 | S | A | -2.6300 | |
| 255 | E | A | -2.9531 | |
| 256 | L | A | -2.6225 | |
| 257 | K | A | -3.3954 | |
| 258 | N | A | -3.2710 | |
| 259 | M | A | -3.0325 | |
| 260 | Q | A | -3.3123 | |
| 261 | D | A | -3.8024 | |
| 262 | M | A | -2.5648 | |
| 263 | V | A | -2.9214 | |
| 264 | E | A | -3.2546 | |
| 265 | D | A | -3.5319 | |
| 266 | Y | A | -3.1631 | |
| 267 | R | A | -3.4741 | |
| 268 | N | A | -3.3602 | |
| 269 | K | A | -3.2929 | |
| 270 | Y | A | -3.2653 | |
| 271 | E | A | -3.4985 | |
| 272 | D | A | -3.8246 | |
| 273 | E | A | 0.0000 | |
| 274 | I | A | -2.3430 | |
| 275 | N | A | -3.3370 | |
| 276 | K | A | -3.6279 | |
| 277 | R | A | -2.8003 | |
| 278 | T | A | -2.3977 | |
| 279 | N | A | -3.2113 | |
| 280 | A | A | -2.7928 | |
| 281 | E | A | -2.4398 | |
| 282 | N | A | -2.5598 | |
| 283 | E | A | -2.6643 | |
| 284 | F | A | -2.1295 | |
| 285 | V | A | -0.9026 | |
| 286 | T | A | -1.8093 | |
| 287 | I | A | -2.1043 | |
| 288 | K | A | -2.9405 | |
| 289 | K | A | -3.3240 | |
| 290 | D | A | -3.1129 | |
| 291 | V | A | 0.0000 | |
| 292 | D | A | -2.6595 | |
| 293 | G | A | -1.6034 | |
| 294 | A | A | -0.7506 | |
| 295 | Y | A | 0.6480 | |
| 296 | M | A | 0.9636 | |
| 297 | T | A | 0.1270 | |
| 298 | K | A | -0.0822 | |
| 299 | V | A | 0.8798 | |
| 300 | D | A | -1.0755 | |
| 301 | L | A | -1.5057 | |
| 302 | Q | A | -1.8399 | |
| 303 | A | A | -1.9554 | |
| 304 | K | A | -2.9149 | |
| 305 | L | A | 0.0000 | |
| 306 | D | A | -3.6016 | |
| 307 | N | A | -3.5310 | |
| 308 | L | A | -2.5985 | |
| 309 | Q | A | -3.0002 | |
| 310 | Q | A | -3.1602 | |
| 311 | E | A | -2.3357 | |
| 312 | I | A | 0.0000 | |
| 313 | D | A | -1.5935 | |
| 314 | F | A | 0.4729 | |
| 315 | L | A | -0.1118 | |
| 316 | T | A | -0.3774 | |
| 317 | A | A | -0.0170 | |
| 318 | L | A | 0.2871 | |
| 319 | Y | A | 0.0000 | |
| 320 | Q | A | -1.3080 | |
| 321 | A | A | -1.0462 | |
| 322 | E | A | -1.4032 | |
| 323 | L | A | -0.9770 | |
| 324 | S | A | -1.5497 | |
| 325 | Q | A | -1.9812 | |
| 326 | M | A | -1.0739 | |
| 327 | Q | A | -1.5559 | |
| 328 | T | A | -1.1138 | |
| 329 | Q | A | -0.9618 | |
| 330 | I | A | 1.0385 | |
| 331 | S | A | 0.2731 | |
| 195 | D | B | -1.8351 | |
| 196 | Y | B | -0.6967 | |
| 197 | S | B | -0.9939 | |
| 198 | K | B | -2.1002 | |
| 199 | Y | B | -0.9697 | |
| 200 | Y | B | -0.5169 | |
| 201 | K | B | -2.4852 | |
| 202 | T | B | -1.8256 | |
| 203 | I | B | -1.9400 | |
| 204 | D | B | -3.4849 | |
| 205 | D | B | -3.3758 | |
| 206 | L | B | -2.4706 | |
| 207 | K | B | -2.8674 | |
| 208 | N | B | -2.6263 | |
| 209 | Q | B | -1.8453 | |
| 210 | I | B | -1.8544 | |
| 211 | L | B | -0.0880 | |
| 212 | N | B | -1.5656 | |
| 213 | L | B | -1.6095 | |
| 214 | T | B | -1.0945 | |
| 215 | T | B | -1.1750 | |
| 216 | D | B | -2.2387 | |
| 217 | N | B | -1.6872 | |
| 218 | A | B | -0.7316 | |
| 219 | N | B | -1.2025 | |
| 220 | I | B | -0.7685 | |
| 221 | L | B | 0.0593 | |
| 222 | L | B | 0.2900 | |
| 223 | Q | B | -0.9588 | |
| 224 | I | B | 0.0000 | |
| 225 | D | B | -1.4046 | |
| 226 | N | B | -1.6859 | |
| 227 | A | B | 0.0000 | |
| 228 | R | B | -2.0691 | |
| 229 | L | B | -1.1379 | |
| 230 | A | B | -1.5420 | |
| 231 | A | B | 0.0000 | |
| 232 | D | B | -2.6893 | |
| 233 | D | B | -2.5748 | |
| 234 | F | B | -2.5703 | |
| 235 | R | B | -2.7657 | |
| 236 | L | B | -1.4829 | |
| 237 | K | B | -2.6295 | |
| 238 | Y | B | -2.5526 | |
| 239 | E | B | -2.1875 | |
| 240 | N | B | -2.0759 | |
| 241 | E | B | -1.9009 | |
| 242 | V | B | -1.2064 | |
| 243 | A | B | -0.9827 | |
| 244 | L | B | -0.4686 | |
| 245 | R | B | -1.6966 | |
| 246 | Q | B | -1.9548 | |
| 247 | S | B | -1.3501 | |
| 248 | V | B | -1.6917 | |
| 249 | E | B | -2.4336 | |
| 250 | A | B | -2.1449 | |
| 251 | D | B | -2.9273 | |
| 252 | I | B | -2.6758 | |
| 253 | N | B | -2.9869 | |
| 254 | G | B | -2.4603 | |
| 255 | L | B | -2.7098 | |
| 256 | R | B | -3.9408 | |
| 257 | R | B | -4.0300 | |
| 258 | V | B | -2.1023 | |
| 259 | L | B | -2.6342 | |
| 260 | D | B | -3.2049 | |
| 261 | E | B | -2.7342 | |
| 262 | L | B | 0.0000 | |
| 263 | T | B | -0.6480 | |
| 264 | L | B | -0.0680 | |
| 265 | T | B | -1.1162 | |
| 266 | K | B | -1.0091 | |
| 267 | A | B | -1.1720 | |
| 268 | D | B | -1.8216 | |
| 269 | L | B | -1.9386 | |
| 270 | E | B | -2.5983 | |
| 271 | M | B | -1.3866 | |
| 272 | Q | B | -1.9908 | |
| 273 | I | B | -2.4558 | |
| 274 | E | B | -2.6365 | |
| 275 | S | B | -2.0372 | |
| 276 | L | B | -1.7143 | |
| 277 | T | B | -1.6037 | |
| 278 | E | B | -2.2678 | |
| 279 | E | B | -2.1479 | |
| 280 | L | B | -1.6039 | |
| 281 | A | B | -1.0495 | |
| 282 | Y | B | -0.8174 | |
| 283 | L | B | -1.4399 | |
| 284 | K | B | -2.7522 | |
| 285 | K | B | -3.4184 | |
| 286 | N | B | -3.4911 | |
| 287 | H | B | -3.6130 | |
| 288 | E | B | -4.5227 | |
| 289 | E | B | -5.0356 | |
| 290 | E | B | -3.7568 | |
| 291 | M | B | -3.2757 | |
| 292 | K | B | -4.5052 | |
| 293 | D | B | -3.9863 | |
| 294 | L | B | -2.2597 | |
| 295 | R | B | -3.2767 | |
| 296 | N | B | -2.8967 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine