Project name: 463fb84cb38daa3

Chain sequence(s)	A: MMVLLDVAFVLLEGSDKIGEEADFNRRSKEEFMEEVIQRMDVGQDDSSIHVTVLQYSYYMMVTVEYPFSEAQSSKGDILQRVREIRYQGGNRRTNTGLALRRYLSDHSFLVSQGDDREQQAPNLLVYYMMVVTTGNPASDEEIKRLPGDIQQVVVPIGVGPNANVQQELERIGWWPNAPILIQDFETLPREAPDLVLQRRCCS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5344
• Maximal score value: 1.1574
• Average score: -0.9497
• Total score value: -168.0922

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1495	M	A	0.9097
1496	V	A	0.4922
1497	L	A	0.0000
1498	D	A	0.0000
1499	V	A	0.0000
1500	A	A	0.0000
1501	F	A	0.0000
1502	V	A	0.0000
1503	L	A	0.0000
1504	E	A	0.0000
1505	G	A	0.0000
1506	S	A	0.0000
1507	D	A	-3.4336
1508	K	A	-3.4322
1509	I	A	0.0000
1510	G	A	-2.4315
1511	E	A	-3.0626
1512	A	A	-1.7817
1513	D	A	-2.5074
1514	F	A	0.0000
1515	N	A	-2.9574
1516	R	A	-2.8355
1517	S	A	0.0000
1518	K	A	-2.4972
1519	E	A	-3.1643
1520	F	A	0.0000
1521	M	A	0.0000
1522	E	A	-2.5427
1523	E	A	-3.1315
1524	V	A	0.0000
1525	I	A	0.0000
1526	Q	A	-2.9410
1527	R	A	-3.1921
1528	M	A	0.0000
1529	D	A	-2.3655
1530	V	A	-1.6541
1531	G	A	-1.4994
1532	Q	A	-2.3102
1533	D	A	-2.2445
1534	S	A	-0.9415
1535	I	A	0.0000
1536	H	A	0.0000
1537	V	A	0.0000
1538	T	A	0.0000
1539	V	A	0.0000
1540	L	A	0.0000
1541	Q	A	0.0000
1542	Y	A	0.0000
1543	S	A	0.0000
1544	Y	A	0.6343
1545	M	A	1.0544
1546	V	A	1.0036
1547	T	A	0.6524
1548	V	A	0.6606
1549	E	A	-0.4108
1550	Y	A	0.0000
1551	P	A	-0.2172
1552	F	A	0.0000
1553	S	A	-0.4487
1554	E	A	-1.3200
1555	A	A	-1.1198
1556	Q	A	0.0000
1557	S	A	-1.6133
1558	K	A	-2.2799
1559	G	A	-1.9935
1560	D	A	-2.6666
1561	I	A	0.0000
1562	L	A	0.0000
1563	Q	A	-2.6775
1564	R	A	-2.6075
1565	V	A	0.0000
1566	R	A	-3.4651
1567	E	A	-3.2442
1568	I	A	0.0000
1569	R	A	-2.8602
1570	Y	A	-1.9529
1571	Q	A	-1.0306
1572	G	A	-1.8518
1573	G	A	-1.5282
1574	N	A	-2.3230
1575	R	A	-1.9121
1576	T	A	0.0000
1577	N	A	0.0000
1578	T	A	0.0000
1579	G	A	0.0000
1580	L	A	0.0775
1581	A	A	0.0000
1582	L	A	0.0000
1583	R	A	-1.6319
1584	Y	A	-0.4489
1585	L	A	0.0000
1586	S	A	-0.8990
1587	D	A	-0.8685
1588	H	A	-0.3928
1589	S	A	0.0000
1590	F	A	0.3183
1591	L	A	1.1574
1592	V	A	0.7674
1593	S	A	-0.9819
1594	Q	A	-2.2901
1595	G	A	-2.7608
1596	D	A	-3.3621
1597	R	A	-2.9227
1598	E	A	-3.5344
1599	Q	A	-3.1230
1600	A	A	-1.6822
1601	P	A	-1.1173
1602	N	A	-1.0335
1603	L	A	-0.4650
1604	V	A	0.0000
1605	Y	A	0.0000
1606	M	A	0.0000
1607	V	A	0.0000
1608	T	A	0.0000
1609	G	A	0.0000
1610	N	A	0.0000
1611	P	A	-0.8567
1612	A	A	-0.8993
1613	S	A	-1.0182
1614	D	A	-1.6044
1615	E	A	-2.3710
1616	I	A	0.0000
1617	K	A	-2.9833
1618	R	A	-2.6001
1619	L	A	-1.9191
1620	P	A	-1.5584
1621	G	A	-1.6643
1622	D	A	-2.5564
1623	I	A	0.0000
1624	Q	A	-0.9585
1625	V	A	0.0000
1626	V	A	0.0000
1627	P	A	0.0000
1628	I	A	0.0000
1629	G	A	0.0000
1630	V	A	0.0000
1631	G	A	-1.2670
1632	P	A	-1.0728
1633	N	A	-1.6885
1634	A	A	-0.7548
1635	N	A	-1.0016
1636	V	A	-0.4253
1637	Q	A	-1.5231
1638	E	A	-1.2388
1639	L	A	0.0000
1640	E	A	-1.1527
1641	R	A	-1.6086
1642	I	A	0.0000
1643	G	A	0.0000
1644	W	A	0.1746
1645	P	A	-0.0016
1646	N	A	-0.1879
1647	A	A	-0.0097
1648	P	A	0.0621
1649	I	A	0.0000
1650	L	A	0.7750
1651	I	A	-0.5144
1652	Q	A	-1.4926
1653	D	A	-1.8787
1654	F	A	0.0000
1655	E	A	-2.8046
1656	T	A	-2.3033
1657	L	A	0.0000
1658	P	A	-2.9233
1659	R	A	-3.5143
1660	E	A	-2.9304
1661	A	A	0.0000
1662	P	A	0.0000
1663	D	A	-2.1066
1664	L	A	-1.0143
1665	V	A	0.0000
1666	L	A	-1.3674
1667	Q	A	-1.7752
1668	R	A	-1.6972
1669	C	A	0.0000
1670	C	A	-0.8191
1671	S	A	-0.8053