Project name: 5iv2:B

Chain sequence(s)	B: QVQLKQSGPGLVQQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8708
• Maximal score value: 2.5086
• Average score: -0.5054
• Total score value: -109.1712

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4782
2	V	B	-0.8472
3	Q	B	-1.6145
4	L	B	0.0000
5	K	B	-2.2422
6	Q	B	0.0000
7	S	B	-0.8617
8	G	B	-1.1744
9	P	B	-0.4579
10	G	B	-0.3763
11	L	B	0.1095
12	V	B	-0.5878
13	Q	B	-1.1601
14	P	B	-1.2965
15	S	B	-1.4688
16	Q	B	-1.8518
17	S	B	-1.5382
18	L	B	0.0000
19	S	B	-0.6480
20	I	B	0.0000
21	T	B	-0.5499
22	C	B	0.0000
23	T	B	-1.1735
24	V	B	0.0000
25	S	B	-1.2411
26	G	B	-1.0005
27	F	B	-0.5354
28	S	B	-0.8687
29	L	B	0.0000
30	T	B	-0.9057
31	N	B	-0.8742
32	Y	B	0.3241
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.2741
40	S	B	0.0000
41	P	B	-1.1053
42	G	B	-1.6774
43	K	B	-2.0208
44	G	B	-0.6248
45	L	B	0.7920
46	E	B	0.0000
47	W	B	0.4487
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.5609
53	S	B	-0.6609
54	G	B	-1.2314
55	G	B	-1.5404
56	N	B	-1.9168
57	T	B	-1.4189
58	D	B	-1.3337
59	Y	B	-0.5901
60	N	B	-0.6023
61	T	B	-0.5024
62	P	B	-0.4618
63	F	B	0.0000
64	T	B	-0.5668
65	S	B	-0.5715
66	R	B	-0.9465
67	L	B	0.0000
68	S	B	-1.0556
69	I	B	0.0000
70	N	B	-1.7389
71	K	B	-1.4363
72	D	B	-1.7909
73	N	B	-2.1465
74	S	B	-1.6563
75	K	B	-2.3526
76	S	B	-1.5814
77	Q	B	-1.5221
78	V	B	0.0000
79	F	B	-0.3145
80	F	B	0.0000
81	K	B	-1.5339
82	M	B	0.0000
83	N	B	-1.6088
84	S	B	-1.4052
85	L	B	0.0000
86	Q	B	-1.9989
87	S	B	-1.4498
88	N	B	-2.0602
89	D	B	0.0000
90	T	B	-0.6559
91	A	B	0.0000
92	I	B	0.6384
93	Y	B	0.0000
94	Y	B	-0.0548
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.0006
100	T	B	0.9351
101	Y	B	1.6106
102	Y	B	1.5354
103	D	B	0.3037
104	Y	B	0.2713
105	E	B	-0.8686
106	F	B	0.0557
107	A	B	0.4187
108	Y	B	0.4161
109	W	B	0.1230
110	G	B	0.0000
111	Q	B	-1.4903
112	G	B	-0.6310
113	T	B	0.0000
114	L	B	0.2404
115	V	B	0.0000
116	T	B	-0.1961
117	V	B	0.0000
118	S	B	-0.3789
119	A	B	-0.2089
120	A	B	-0.1958
121	S	B	-0.4165
122	T	B	-0.6730
123	K	B	-1.2009
124	G	B	-1.3477
125	P	B	0.0000
126	S	B	-0.1185
127	V	B	0.0000
128	F	B	0.9604
129	P	B	-0.1067
130	L	B	0.3234
131	A	B	-0.8995
132	P	B	0.0000
133	S	B	-0.8976
134	S	B	-0.5432
139	G	B	-0.7677
140	G	B	-0.8940
141	T	B	-0.6227
142	A	B	-0.3902
143	A	B	0.0798
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.6425
148	V	B	0.0000
149	K	B	-0.2943
150	D	B	-0.7567
151	Y	B	0.0000
152	F	B	-0.2106
153	P	B	0.0000
154	E	B	-0.0083
155	P	B	-0.4149
156	V	B	-0.4700
157	T	B	-0.4637
158	V	B	-0.3772
159	S	B	-0.4740
160	W	B	0.0000
161	N	B	-0.9259
162	S	B	-0.7011
163	G	B	-0.5796
164	A	B	-0.2603
165	L	B	-0.0787
166	T	B	-0.3406
167	S	B	-0.3746
168	G	B	-0.4445
169	V	B	-0.1361
170	H	B	-0.5838
171	T	B	0.1186
172	F	B	0.9405
173	P	B	0.7320
174	A	B	1.3056
175	V	B	2.5086
176	L	B	2.1810
177	Q	B	0.6734
178	S	B	0.0956
179	S	B	-0.2344
180	G	B	0.2375
181	L	B	0.3302
182	Y	B	0.8858
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6258
186	S	B	0.0000
187	V	B	0.3339
188	V	B	0.0000
189	T	B	-0.2259
190	V	B	0.0000
191	P	B	-0.5617
192	S	B	-0.6565
193	S	B	-0.6224
194	S	B	-0.6364
195	L	B	-0.7647
196	G	B	-0.9431
197	T	B	-0.7117
198	Q	B	-1.2212
199	T	B	-1.1471
200	Y	B	0.0000
201	I	B	-1.4801
202	C	B	0.0000
203	N	B	-1.4689
204	V	B	0.0000
205	N	B	-1.6973
206	H	B	0.0000
207	K	B	-2.5012
208	P	B	-1.4221
209	S	B	-1.6755
210	N	B	-2.4193
211	T	B	-1.9271
212	K	B	-2.5550
213	V	B	-1.6727
214	D	B	-2.5908
215	K	B	-2.1063
216	R	B	-2.5754
217	V	B	0.0000
218	E	B	-2.8708
219	P	B	-1.9248
220	K	B	-2.2920