Project name: 4z5r:L
Status: done
submitted: 2019-03-20 20:23:17, status changed: 2019-03-20 20:35:03
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRASQSVSTSSYSYMHWYQQKPGKAPKVLISYASNLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQHSWGIPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6543
-
Maximal score value
-
1.4743
-
Average score
-
-0.8184
-
Total score value
-
-177.6009
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.1471 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-2.2485 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.1854 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.8175 |
|
| 8 |
P |
L |
-0.5410 |
|
| 9 |
S |
L |
-0.9684 |
|
| 10 |
S |
L |
-1.0078 |
|
| 11 |
L |
L |
-0.8161 |
|
| 12 |
S |
L |
-1.0960 |
|
| 13 |
A |
L |
-1.2556 |
|
| 14 |
S |
L |
-1.2308 |
|
| 15 |
V |
L |
-0.4356 |
|
| 16 |
G |
L |
-0.8515 |
|
| 17 |
D |
L |
-1.9078 |
|
| 18 |
R |
L |
-2.3193 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6023 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.8070 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.4003 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-1.8381 |
|
| 27 |
Q |
L |
-1.8714 |
|
| 27A |
S |
L |
-0.9542 |
|
| 27B |
V |
L |
0.0000 |
|
| 27C |
S |
L |
0.2266 |
|
| 27D |
T |
L |
0.2645 |
|
| 28 |
S |
L |
-0.0287 |
|
| 29 |
S |
L |
0.2720 |
|
| 30 |
Y |
L |
1.3523 |
|
| 31 |
S |
L |
0.0000 |
|
| 32 |
Y |
L |
0.8902 |
|
| 33 |
M |
L |
0.0000 |
|
| 34 |
H |
L |
0.3675 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0732 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.4691 |
|
| 39 |
K |
L |
-1.9126 |
|
| 40 |
P |
L |
-1.4712 |
|
| 41 |
G |
L |
-1.6682 |
|
| 42 |
K |
L |
-2.3458 |
|
| 43 |
A |
L |
-1.4017 |
|
| 44 |
P |
L |
-1.3609 |
|
| 45 |
K |
L |
-1.7079 |
|
| 46 |
V |
L |
-0.4129 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
S |
L |
-0.0425 |
|
| 50 |
Y |
L |
0.7488 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.5210 |
|
| 53 |
N |
L |
-1.1051 |
|
| 54 |
L |
L |
-0.4072 |
|
| 55 |
E |
L |
-1.0815 |
|
| 56 |
S |
L |
-0.7599 |
|
| 57 |
G |
L |
-0.6412 |
|
| 58 |
V |
L |
-0.4514 |
|
| 59 |
P |
L |
-0.3936 |
|
| 60 |
S |
L |
-0.4616 |
|
| 61 |
R |
L |
-0.8103 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.5603 |
|
| 64 |
G |
L |
-0.4033 |
|
| 65 |
S |
L |
-0.7763 |
|
| 66 |
G |
L |
-1.0357 |
|
| 67 |
S |
L |
-0.6216 |
|
| 68 |
G |
L |
-0.9192 |
|
| 69 |
T |
L |
-1.7074 |
|
| 70 |
D |
L |
-2.4482 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7983 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6096 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.4188 |
|
| 77 |
S |
L |
-1.2025 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.1237 |
|
| 80 |
P |
L |
-1.9259 |
|
| 81 |
E |
L |
-2.0160 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
-0.1178 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
-0.0813 |
|
| 90 |
H |
L |
0.0000 |
|
| 91 |
S |
L |
0.1223 |
|
| 92 |
W |
L |
0.0899 |
|
| 93 |
G |
L |
0.0761 |
|
| 94 |
I |
L |
0.8364 |
|
| 95 |
P |
L |
-0.2734 |
|
| 96 |
R |
L |
-1.4259 |
|
| 97 |
T |
L |
-0.7854 |
|
| 98 |
F |
L |
0.2382 |
|
| 99 |
G |
L |
-0.5024 |
|
| 100 |
Q |
L |
-1.2594 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.9335 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.7695 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.8686 |
|
| 108 |
R |
L |
-1.1741 |
|
| 109 |
T |
L |
-0.1159 |
|
| 110 |
V |
L |
0.3906 |
|
| 111 |
A |
L |
-0.1369 |
|
| 112 |
A |
L |
-0.2624 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1587 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.4173 |
|
| 117 |
I |
L |
1.3225 |
|
| 118 |
F |
L |
1.4743 |
|
| 119 |
P |
L |
-0.1736 |
|
| 120 |
P |
L |
-0.9463 |
|
| 121 |
S |
L |
-1.9496 |
|
| 122 |
D |
L |
-3.4145 |
|
| 123 |
E |
L |
-3.6543 |
|
| 124 |
Q |
L |
-2.9683 |
|
| 125 |
L |
L |
0.0000 |
|
| 126 |
K |
L |
-3.3371 |
|
| 127 |
S |
L |
-2.2487 |
|
| 128 |
G |
L |
-1.3844 |
|
| 129 |
T |
L |
-1.4888 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
-0.0559 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7095 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5020 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.7243 |
|
| 138 |
N |
L |
-1.6633 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
-1.3545 |
|
| 141 |
P |
L |
-1.8323 |
|
| 142 |
R |
L |
-3.1267 |
|
| 143 |
E |
L |
-3.2499 |
|
| 144 |
A |
L |
-2.3772 |
|
| 145 |
K |
L |
-2.4039 |
|
| 146 |
V |
L |
-1.0091 |
|
| 147 |
Q |
L |
-0.5006 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.6542 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-2.3216 |
|
| 152 |
N |
L |
-1.7235 |
|
| 153 |
A |
L |
-0.3455 |
|
| 154 |
L |
L |
0.7430 |
|
| 155 |
Q |
L |
-0.0221 |
|
| 156 |
S |
L |
-0.4873 |
|
| 157 |
G |
L |
-1.0016 |
|
| 158 |
N |
L |
-0.9735 |
|
| 159 |
S |
L |
-1.4115 |
|
| 160 |
Q |
L |
-2.3285 |
|
| 161 |
E |
L |
-2.3183 |
|
| 162 |
S |
L |
-1.2897 |
|
| 163 |
V |
L |
-0.7177 |
|
| 164 |
T |
L |
-1.1904 |
|
| 165 |
E |
L |
-2.2254 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.1905 |
|
| 168 |
S |
L |
-2.3298 |
|
| 169 |
K |
L |
-2.8964 |
|
| 170 |
D |
L |
-2.6942 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-1.0531 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.3938 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6426 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.4568 |
|
| 181 |
L |
L |
-0.6611 |
|
| 182 |
S |
L |
-1.1553 |
|
| 183 |
K |
L |
-2.2938 |
|
| 184 |
A |
L |
-1.8444 |
|
| 185 |
D |
L |
-2.5277 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.1452 |
|
| 188 |
K |
L |
-3.5070 |
|
| 189 |
H |
L |
-3.0586 |
|
| 190 |
K |
L |
-3.3645 |
|
| 191 |
V |
L |
-1.7552 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.8623 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2077 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7405 |
|
| 200 |
G |
L |
-0.4102 |
|
| 201 |
L |
L |
-0.2438 |
|
| 202 |
S |
L |
-0.4862 |
|
| 203 |
S |
L |
-0.4481 |
|
| 204 |
P |
L |
-0.5564 |
|
| 205 |
V |
L |
-0.0169 |
|
| 206 |
T |
L |
-0.4176 |
|
| 207 |
K |
L |
-0.5019 |
|
| 208 |
S |
L |
-0.4131 |
|
| 209 |
F |
L |
-0.9082 |
|
| 210 |
N |
L |
-2.1012 |
|
| 211 |
R |
L |
-2.5780 |
|
| 212 |
G |
L |
-2.1155 |
|
| 213 |
E |
L |
-2.5320 |
|