Project name: 5F1 protein
Status: done
submitted: 2018-11-16 09:23:15, status changed: 2018-11-16 09:28:43
Settings
|
Chain sequence(s)
|
A: MKSFLLSPVLALLWVSTAQAEVLVQPDFDAEKFSGLWYVVSMVSDCKVFLGKKDHLLMSTRAIKATAGGDLSVHMEFPGADGCTQVDAEYLKVGSAGHFRVPALGYLDVRVADTDYSSFAVVYIYKELEGALSTMVQLYSRTQDASPQALKALRDFYPTVGLPDDMMVLLPKSDACSPRD
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-3.1541
-
Maximal score value
-
2.1142
-
Average score
-
-0.6376
-
Total score value
-
-114.7716
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
M |
A |
0.7245 |
|
| 2 |
K |
A |
-0.6853 |
|
| 3 |
S |
A |
0.5109 |
|
| 4 |
F |
A |
2.0885 |
|
| 5 |
L |
A |
1.5804 |
|
| 6 |
L |
A |
0.7610 |
|
| 7 |
S |
A |
0.8456 |
|
| 8 |
P |
A |
1.5068 |
|
| 9 |
V |
A |
0.0000 |
|
| 10 |
L |
A |
1.8888 |
|
| 11 |
A |
A |
1.8103 |
|
| 12 |
L |
A |
2.1142 |
|
| 13 |
L |
A |
1.2979 |
|
| 14 |
W |
A |
0.0000 |
|
| 15 |
V |
A |
0.6458 |
|
| 16 |
S |
A |
0.5364 |
|
| 17 |
T |
A |
0.2772 |
|
| 18 |
A |
A |
-0.2895 |
|
| 19 |
Q |
A |
-0.7940 |
|
| 20 |
A |
A |
-0.6727 |
|
| 21 |
E |
A |
-0.3125 |
|
| 22 |
V |
A |
1.1297 |
|
| 23 |
L |
A |
0.0000 |
|
| 24 |
V |
A |
0.3209 |
|
| 25 |
Q |
A |
0.1763 |
|
| 26 |
P |
A |
-0.6406 |
|
| 27 |
D |
A |
-1.8780 |
|
| 28 |
F |
A |
-1.4145 |
|
| 29 |
D |
A |
-2.1653 |
|
| 30 |
A |
A |
-2.2228 |
|
| 31 |
E |
A |
-3.1541 |
|
| 32 |
K |
A |
-2.9561 |
|
| 33 |
F |
A |
0.0000 |
|
| 34 |
S |
A |
-1.8235 |
|
| 35 |
G |
A |
-1.0746 |
|
| 36 |
L |
A |
-0.2641 |
|
| 37 |
W |
A |
0.0000 |
|
| 38 |
Y |
A |
-0.8150 |
|
| 39 |
V |
A |
0.0000 |
|
| 40 |
V |
A |
0.0000 |
|
| 41 |
S |
A |
0.0000 |
|
| 42 |
M |
A |
0.0000 |
|
| 43 |
V |
A |
0.0000 |
|
| 44 |
S |
A |
0.0000 |
|
| 45 |
D |
A |
-0.4189 |
|
| 46 |
C |
A |
0.1881 |
|
| 47 |
K |
A |
-0.4836 |
|
| 48 |
V |
A |
0.1577 |
|
| 49 |
F |
A |
-0.3779 |
|
| 50 |
L |
A |
0.0000 |
|
| 51 |
G |
A |
-1.2869 |
|
| 52 |
K |
A |
-2.9580 |
|
| 53 |
K |
A |
-2.8424 |
|
| 54 |
D |
A |
0.0000 |
|
| 55 |
H |
A |
-1.1328 |
|
| 56 |
L |
A |
0.0000 |
|
| 57 |
L |
A |
0.0000 |
|
| 58 |
M |
A |
-0.0136 |
|
| 59 |
S |
A |
0.0000 |
|
| 60 |
T |
A |
0.0000 |
|
| 61 |
R |
A |
-1.3389 |
|
| 62 |
A |
A |
-0.9605 |
|
| 63 |
I |
A |
0.0000 |
|
| 64 |
K |
A |
-2.4162 |
|
| 65 |
A |
A |
-1.9043 |
|
| 66 |
T |
A |
-1.0558 |
|
| 67 |
A |
A |
-0.4591 |
|
| 68 |
G |
A |
-0.7694 |
|
| 69 |
G |
A |
-1.1891 |
|
| 70 |
D |
A |
-1.4860 |
|
| 71 |
L |
A |
0.0000 |
|
| 72 |
S |
A |
-1.6783 |
|
| 73 |
V |
A |
0.0000 |
|
| 74 |
H |
A |
-1.6252 |
|
| 75 |
M |
A |
-0.8574 |
|
| 76 |
E |
A |
0.0000 |
|
| 77 |
F |
A |
-0.7379 |
|
| 78 |
P |
A |
-1.8487 |
|
| 79 |
G |
A |
-1.8001 |
|
| 80 |
A |
A |
-1.6419 |
|
| 81 |
D |
A |
-2.6864 |
|
| 82 |
G |
A |
-1.3734 |
|
| 83 |
C |
A |
-1.3590 |
|
| 84 |
T |
A |
-0.9939 |
|
| 85 |
Q |
A |
-1.8468 |
|
| 86 |
V |
A |
-0.8486 |
|
| 87 |
D |
A |
-2.2653 |
|
| 88 |
A |
A |
-1.5683 |
|
| 89 |
E |
A |
-2.6554 |
|
| 90 |
Y |
A |
0.0000 |
|
| 91 |
L |
A |
-1.0006 |
|
| 92 |
K |
A |
-2.0687 |
|
| 93 |
V |
A |
-1.1084 |
|
| 94 |
G |
A |
-0.8652 |
|
| 95 |
S |
A |
-0.7784 |
|
| 96 |
A |
A |
-0.9581 |
|
| 97 |
G |
A |
-1.2936 |
|
| 98 |
H |
A |
-1.1435 |
|
| 99 |
F |
A |
0.0000 |
|
| 100 |
R |
A |
-1.8641 |
|
| 101 |
V |
A |
0.0000 |
|
| 102 |
P |
A |
-0.3861 |
|
| 103 |
A |
A |
-0.0150 |
|
| 104 |
L |
A |
0.8576 |
|
| 105 |
G |
A |
0.2994 |
|
| 106 |
Y |
A |
0.0161 |
|
| 107 |
L |
A |
0.0000 |
|
| 108 |
D |
A |
-0.8304 |
|
| 109 |
V |
A |
0.0000 |
|
| 110 |
R |
A |
-0.7015 |
|
| 111 |
V |
A |
-0.2592 |
|
| 112 |
A |
A |
0.0000 |
|
| 113 |
D |
A |
0.0000 |
|
| 114 |
T |
A |
0.0000 |
|
| 115 |
D |
A |
0.1834 |
|
| 116 |
Y |
A |
-0.3150 |
|
| 117 |
S |
A |
-0.5313 |
|
| 118 |
S |
A |
-0.5184 |
|
| 119 |
F |
A |
0.0000 |
|
| 120 |
A |
A |
0.0000 |
|
| 121 |
V |
A |
0.0000 |
|
| 122 |
V |
A |
0.0000 |
|
| 123 |
Y |
A |
0.0000 |
|
| 124 |
I |
A |
0.0000 |
|
| 125 |
Y |
A |
0.1682 |
|
| 126 |
K |
A |
0.0000 |
|
| 127 |
E |
A |
-0.3217 |
|
| 128 |
L |
A |
-0.2914 |
|
| 129 |
E |
A |
-1.7522 |
|
| 130 |
G |
A |
-1.0104 |
|
| 131 |
A |
A |
0.0068 |
|
| 132 |
L |
A |
0.9417 |
|
| 133 |
S |
A |
0.0000 |
|
| 134 |
T |
A |
0.0000 |
|
| 135 |
M |
A |
0.0000 |
|
| 136 |
V |
A |
0.0000 |
|
| 137 |
Q |
A |
0.0000 |
|
| 138 |
L |
A |
0.0000 |
|
| 139 |
Y |
A |
0.0000 |
|
| 140 |
S |
A |
0.0000 |
|
| 141 |
R |
A |
-0.9997 |
|
| 142 |
T |
A |
-1.2909 |
|
| 143 |
Q |
A |
-2.0306 |
|
| 144 |
D |
A |
-2.2883 |
|
| 145 |
A |
A |
-1.3027 |
|
| 146 |
S |
A |
-1.1147 |
|
| 147 |
P |
A |
-1.4324 |
|
| 148 |
Q |
A |
-1.9397 |
|
| 149 |
A |
A |
0.0000 |
|
| 150 |
L |
A |
-1.4123 |
|
| 151 |
K |
A |
-2.4502 |
|
| 152 |
A |
A |
-1.4134 |
|
| 153 |
L |
A |
0.0000 |
|
| 154 |
R |
A |
-1.8918 |
|
| 155 |
D |
A |
-1.3479 |
|
| 156 |
F |
A |
0.0000 |
|
| 157 |
Y |
A |
0.0000 |
|
| 158 |
P |
A |
-0.7325 |
|
| 159 |
T |
A |
0.3802 |
|
| 160 |
V |
A |
0.0000 |
|
| 161 |
G |
A |
-0.4759 |
|
| 162 |
L |
A |
-0.8936 |
|
| 163 |
P |
A |
-1.6713 |
|
| 164 |
D |
A |
-2.6094 |
|
| 165 |
D |
A |
-2.4897 |
|
| 166 |
M |
A |
-1.1566 |
|
| 167 |
M |
A |
-0.7801 |
|
| 168 |
V |
A |
-0.1265 |
|
| 169 |
L |
A |
0.2556 |
|
| 170 |
L |
A |
0.0000 |
|
| 171 |
P |
A |
-1.6631 |
|
| 172 |
K |
A |
-2.2205 |
|
| 173 |
S |
A |
-1.9548 |
|
| 174 |
D |
A |
-2.6729 |
|
| 175 |
A |
A |
0.0000 |
|
| 176 |
C |
A |
0.0000 |
|
| 177 |
S |
A |
-1.9762 |
|
| 178 |
P |
A |
-1.9179 |
|
| 179 |
R |
A |
-3.1141 |
|
| 180 |
D |
A |
-3.0161 |
|