Project name: 5ff6:B

Chain sequence(s)	B: QVQLKQSGPGLVQQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9115
• Maximal score value: 2.5034
• Average score: -0.5155
• Total score value: -113.4011

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4989
2	V	B	-0.9139
3	Q	B	-1.6490
4	L	B	0.0000
5	K	B	-1.9843
6	Q	B	-1.2196
7	S	B	-0.7599
8	G	B	-1.0376
9	P	B	-0.4028
10	G	B	-0.3469
11	L	B	-0.0540
12	V	B	-0.7835
13	Q	B	-1.5689
14	P	B	-1.4024
15	S	B	-1.4534
16	Q	B	-1.7342
17	S	B	-1.3974
18	L	B	0.0000
19	S	B	-0.4961
20	I	B	0.0000
21	T	B	-0.4686
22	C	B	0.0000
23	T	B	-1.0909
24	V	B	0.0000
25	S	B	-1.0451
26	G	B	-1.0043
27	F	B	-0.5364
28	S	B	-0.8551
29	L	B	0.0000
30	T	B	-0.8892
31	N	B	-0.8753
32	Y	B	0.3809
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.2570
40	S	B	-0.9157
41	P	B	-1.1074
42	G	B	-1.6420
43	K	B	-2.0484
44	G	B	-0.6786
45	L	B	0.7368
46	E	B	0.0795
47	W	B	0.4983
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.4059
53	S	B	-0.6412
54	G	B	-1.2053
55	G	B	-1.4839
56	N	B	-1.8721
57	T	B	-1.3683
58	D	B	-1.2591
59	Y	B	-0.5710
60	N	B	-0.6473
61	T	B	-0.5153
62	P	B	-0.4739
63	F	B	0.0000
64	T	B	-0.5619
65	S	B	-0.5724
66	R	B	-0.8485
67	L	B	0.0000
68	S	B	-0.9257
69	I	B	0.0000
70	N	B	-1.6721
71	K	B	-1.3979
72	D	B	-1.7208
73	N	B	-2.0907
74	S	B	-1.6254
75	K	B	-2.3091
76	S	B	-1.5189
77	Q	B	-1.4576
78	V	B	0.0000
79	F	B	-0.2367
80	F	B	0.0000
81	K	B	-1.1592
82	M	B	0.0000
83	N	B	-1.4237
84	S	B	-1.3278
85	L	B	0.0000
86	Q	B	-2.0663
87	S	B	-1.5449
88	N	B	-2.0738
89	D	B	0.0000
90	T	B	-0.6594
91	A	B	0.0000
92	I	B	0.5362
93	Y	B	0.0000
94	Y	B	-0.0549
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.6565
100	T	B	1.3604
101	Y	B	1.9398
102	Y	B	1.8332
103	D	B	0.9734
104	Y	B	1.0614
105	E	B	0.2286
106	F	B	0.7334
107	A	B	0.7947
108	Y	B	0.5112
109	W	B	0.1237
110	G	B	0.0000
111	Q	B	-1.4449
112	G	B	-0.5739
113	T	B	0.0000
114	L	B	0.4489
115	V	B	0.0000
116	T	B	-0.2749
117	V	B	0.0000
118	S	B	-0.6725
119	A	B	-0.3845
120	A	B	-0.3200
121	S	B	-0.5160
122	T	B	-0.7347
123	K	B	-1.2757
124	G	B	-1.4922
125	P	B	0.0000
126	S	B	-0.0958
127	V	B	0.0000
128	F	B	1.2472
129	P	B	0.0004
130	L	B	0.4137
131	A	B	-1.0299
132	P	B	0.0000
133	S	B	-1.4541
134	S	B	-1.1960
135	K	B	-1.9153
136	S	B	-1.0468
137	T	B	-1.0275
138	S	B	-0.9837
139	G	B	-0.8411
140	G	B	-0.8963
141	T	B	-0.6629
142	A	B	0.0000
143	A	B	-0.2067
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.7091
148	V	B	0.0000
149	K	B	-0.1946
150	D	B	-0.7809
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.1083
155	P	B	-0.5330
156	V	B	-0.6705
157	T	B	-0.6319
158	V	B	-0.3170
159	S	B	-0.5239
160	W	B	0.0000
161	N	B	-0.8523
162	S	B	-0.6952
163	G	B	-0.5456
164	A	B	-0.2463
165	L	B	-0.0305
166	T	B	-0.2915
167	S	B	-0.3056
168	G	B	-0.3396
169	V	B	-0.0627
170	H	B	-0.5126
171	T	B	0.1308
172	F	B	0.9668
173	P	B	0.5876
174	A	B	1.3111
175	V	B	2.5034
176	L	B	2.1552
177	Q	B	0.6620
178	S	B	0.0869
179	S	B	-0.2448
180	G	B	0.2154
181	L	B	0.2500
182	Y	B	0.8173
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6607
186	S	B	0.0000
187	V	B	0.2991
188	V	B	0.0000
189	T	B	-0.2001
190	V	B	0.0000
191	P	B	-0.5349
192	S	B	-0.5950
193	S	B	-0.5917
194	S	B	-0.6412
195	L	B	-0.8058
196	G	B	-0.9650
197	T	B	-0.7629
198	Q	B	-1.3004
199	T	B	-1.2491
200	Y	B	0.0000
201	I	B	-1.6003
202	C	B	0.0000
203	N	B	-1.6308
204	V	B	0.0000
205	N	B	-2.1542
206	H	B	0.0000
207	K	B	-2.8677
208	P	B	-1.6409
209	S	B	-1.8618
210	N	B	-2.6266
211	T	B	-2.1359
212	K	B	-2.8140
213	V	B	-1.8629
214	D	B	-2.7261
215	K	B	-2.2376
216	R	B	-2.7057
217	V	B	0.0000
218	E	B	-2.9115
219	P	B	-1.9059
220	K	B	-2.2467