Project name: 5ir1:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8907
• Maximal score value: 2.4716
• Average score: -0.5195
• Total score value: -114.2849

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4678
2	V	B	-0.8416
3	Q	B	-1.7247
4	L	B	0.0000
5	K	B	-2.0089
6	Q	B	-1.1093
7	S	B	-0.7948
8	G	B	-0.9846
9	P	B	-0.4182
10	G	B	-0.3636
11	L	B	-0.0254
12	V	B	-0.6819
13	Q	B	-1.3423
14	P	B	-1.4766
15	S	B	-1.4387
16	Q	B	-1.7475
17	S	B	-1.4338
18	L	B	0.0000
19	S	B	-0.5612
20	I	B	0.0000
21	T	B	-0.4990
22	C	B	0.0000
23	T	B	-1.1223
24	V	B	0.0000
25	S	B	-1.1804
26	G	B	-0.8361
27	F	B	-0.4421
28	S	B	-0.8103
29	L	B	0.0000
30	T	B	-0.8914
31	N	B	-0.8650
32	Y	B	0.3428
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.4082
40	S	B	-0.9921
41	P	B	-1.1618
42	G	B	-1.7087
43	K	B	-2.0377
44	G	B	-0.6595
45	L	B	0.7578
46	E	B	0.0000
47	W	B	0.4520
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.6141
53	S	B	-0.6379
54	G	B	-1.2269
55	G	B	-1.5251
56	N	B	-1.9561
57	T	B	-1.5253
58	D	B	-1.5459
59	Y	B	-0.6447
60	N	B	-0.5802
61	T	B	-0.5025
62	P	B	-0.4493
63	F	B	0.0000
64	T	B	-0.5738
65	S	B	-0.5398
66	R	B	-0.8948
67	L	B	0.0000
68	S	B	-1.0102
69	I	B	0.0000
70	N	B	-1.7235
71	K	B	-1.4787
72	D	B	-1.7676
73	N	B	-2.1961
74	S	B	-1.6679
75	K	B	-2.3551
76	S	B	-1.5760
77	Q	B	-1.5174
78	V	B	0.0000
79	F	B	-0.2817
80	F	B	0.0000
81	K	B	-1.3506
82	M	B	0.0000
83	N	B	-1.4935
84	S	B	-1.3321
85	L	B	0.0000
86	Q	B	-1.9875
87	S	B	-1.4794
88	N	B	-2.0787
89	D	B	0.0000
90	T	B	-0.6964
91	A	B	0.0000
92	I	B	0.4922
93	Y	B	0.0000
94	Y	B	-0.0869
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.0563
100	T	B	0.9428
101	Y	B	1.6038
102	Y	B	1.5088
103	D	B	0.2535
104	Y	B	0.1682
105	E	B	-0.8996
106	F	B	0.0819
107	A	B	0.4523
108	Y	B	0.3892
109	W	B	0.1023
110	G	B	0.0000
111	Q	B	-1.4755
112	G	B	-0.6657
113	T	B	0.0000
114	L	B	0.1719
115	V	B	0.0000
116	T	B	-0.2870
117	V	B	0.0000
118	S	B	-0.6131
119	A	B	-0.2870
120	A	B	-0.2744
121	S	B	-0.5001
122	T	B	-0.8479
123	K	B	-1.2196
124	G	B	-1.4038
125	P	B	0.0000
126	S	B	-0.0589
127	V	B	0.0000
128	F	B	1.1999
129	P	B	0.0287
130	L	B	0.4488
131	A	B	-1.0448
132	P	B	0.0000
133	S	B	-1.3829
134	S	B	-1.1670
135	K	B	-1.8939
136	S	B	-1.0163
137	T	B	-1.0175
138	S	B	-0.9333
139	G	B	-0.8582
140	G	B	-0.9161
141	T	B	-0.6683
142	A	B	0.0000
143	A	B	-0.1738
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.7999
148	V	B	0.0000
149	K	B	-0.1631
150	D	B	-0.6238
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.0735
155	P	B	-0.4735
156	V	B	-0.5766
157	T	B	-0.5433
158	V	B	-0.1896
159	S	B	-0.3949
160	W	B	0.0000
161	N	B	-0.8242
162	S	B	-0.5912
163	G	B	-0.5707
164	A	B	-0.2415
165	L	B	-0.0469
166	T	B	-0.2889
167	S	B	-0.3703
168	G	B	-0.4586
169	V	B	0.0529
170	H	B	-0.3286
171	T	B	0.2271
172	F	B	1.0476
173	P	B	0.7817
174	A	B	1.3070
175	V	B	2.4716
176	L	B	2.0935
177	Q	B	0.6696
178	S	B	0.0794
179	S	B	-0.2191
180	G	B	0.2334
181	L	B	0.2944
182	Y	B	0.8458
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.7350
186	S	B	0.0000
187	V	B	0.5084
188	V	B	0.0000
189	T	B	-0.2296
190	V	B	0.0000
191	P	B	-0.5471
192	S	B	-0.6028
193	S	B	-0.5969
194	S	B	-0.5956
195	L	B	-0.7947
196	G	B	-0.9584
197	T	B	-0.7381
198	Q	B	-1.2660
199	T	B	-1.2243
200	Y	B	0.0000
201	I	B	-1.3666
202	C	B	0.0000
203	N	B	-1.2643
204	V	B	0.0000
205	N	B	-1.8313
206	H	B	0.0000
207	K	B	-2.4146
208	P	B	-1.3930
209	S	B	-1.7074
210	N	B	-2.4385
211	T	B	-1.9864
212	K	B	-2.5052
213	V	B	-1.4022
214	D	B	-1.8364
215	K	B	-1.7514
216	R	B	-2.4868
217	V	B	0.0000
218	E	B	-2.8907
219	P	B	-1.9014
220	K	B	-2.2415