Project name: aggre site

Chain sequence(s)	A: MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.9293
• Maximal score value: 3.1017
• Average score: -0.8853
• Total score value: -123.9384

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.8582
2	D	A	0.1253
3	V	A	1.8574
4	F	A	2.0288
5	M	A	0.9152
6	K	A	-0.7769
7	G	A	-0.5719
8	L	A	-0.3400
9	S	A	-1.8773
10	K	A	-2.7903
11	A	A	-1.7126
12	K	A	-2.0205
13	E	A	-2.1969
14	G	A	-0.6961
15	V	A	0.8969
16	V	A	0.8269
17	A	A	-0.5687
18	A	A	-0.8598
19	A	A	-1.1145
20	E	A	-2.9496
21	K	A	-3.1913
22	T	A	-2.1036
23	K	A	-3.2783
24	Q	A	-3.1483
25	G	A	-1.8130
26	V	A	-0.2539
27	A	A	-1.3687
28	E	A	-2.5363
29	A	A	-1.4076
30	A	A	-1.5013
31	G	A	-2.5455
32	K	A	-3.1987
33	T	A	-2.2330
34	K	A	-2.8331
35	E	A	-1.9961
36	G	A	-0.5809
37	V	A	1.4956
38	L	A	1.9461
39	Y	A	1.9456
40	V	A	0.6415
41	G	A	-0.4845
42	S	A	-1.0910
43	K	A	-2.1508
44	T	A	-1.8823
45	K	A	-2.6661
46	E	A	-2.5784
47	G	A	-1.5595
48	V	A	-0.1915
49	V	A	0.6421
50	H	A	-0.1499
51	G	A	0.6949
52	V	A	2.3660
53	A	A	0.8962
54	T	A	0.4091
55	V	A	0.8586
56	A	A	-0.7523
57	E	A	-2.8278
58	K	A	-3.2236
59	T	A	-2.3336
60	K	A	-3.5842
61	E	A	-3.9293
62	Q	A	-2.7296
63	V	A	-0.2793
64	T	A	-1.4397
65	N	A	-1.4275
66	V	A	0.7597
67	G	A	0.5787
68	G	A	0.7393
69	A	A	1.6432
70	V	A	3.1017
71	V	A	3.0445
72	T	A	1.9692
73	G	A	2.1496
74	V	A	2.9647
75	T	A	1.4674
76	A	A	0.9223
77	V	A	1.3338
78	A	A	0.3304
79	Q	A	-1.1649
80	K	A	-1.5455
81	T	A	-0.6776
82	V	A	0.0339
83	E	A	-1.7228
84	G	A	-0.9781
85	A	A	0.0959
86	G	A	-0.1821
87	S	A	0.3215
88	I	A	1.4869
89	A	A	0.9232
90	A	A	1.2356
91	A	A	1.2745
92	T	A	1.0202
93	G	A	0.9125
94	F	A	1.8629
95	V	A	1.1823
96	K	A	-1.7131
97	K	A	-2.7409
98	D	A	-3.0747
99	Q	A	-2.2090
100	L	A	-0.6707
101	G	A	-1.6529
102	K	A	-2.9237
103	N	A	-3.5657
104	E	A	-3.8963
105	E	A	-3.7178
106	G	A	-2.2185
107	A	A	-1.7389
108	P	A	-1.9036
109	Q	A	-2.6251
110	E	A	-2.6355
111	G	A	-1.0127
112	I	A	1.0794
113	L	A	0.2822
114	E	A	-1.6918
115	D	A	-1.4617
116	M	A	0.1734
117	P	A	-0.1232
118	V	A	0.0324
119	D	A	-2.1444
120	P	A	-2.3277
121	D	A	-2.9558
122	N	A	-2.5713
123	E	A	-2.6492
124	A	A	-1.2297
125	Y	A	-0.3116
126	E	A	-1.9871
127	M	A	-0.8153
128	P	A	-1.2846
129	S	A	-1.6613
130	E	A	-2.7938
131	E	A	-2.7542
132	G	A	-2.0398
133	Y	A	-0.6750
134	Q	A	-1.8112
135	D	A	-2.2074
136	Y	A	-1.0889
137	E	A	-2.3465
138	P	A	-1.8129
139	E	A	-2.0778
140	A	A	-1.1262