Project name: 4k3j:L
Status: done
submitted: 2019-03-20 20:19:25, status changed: 2019-03-20 20:28:06
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCKSSQSLLYTSSQKNYLAWYQQKPGKAPKLLIYWASTRESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYYAYPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7892
-
Maximal score value
-
1.5588
-
Average score
-
-0.7793
-
Total score value
-
-169.1068
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.8401 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.9790 |
|
| 4 |
M |
L |
-1.1852 |
|
| 5 |
T |
L |
-1.1460 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.7087 |
|
| 8 |
P |
L |
-0.6401 |
|
| 9 |
S |
L |
-0.9235 |
|
| 10 |
S |
L |
-0.8135 |
|
| 11 |
L |
L |
-0.5232 |
|
| 12 |
S |
L |
-0.8650 |
|
| 13 |
A |
L |
-1.0120 |
|
| 14 |
S |
L |
-0.9971 |
|
| 15 |
V |
L |
-0.4282 |
|
| 16 |
G |
L |
-0.9753 |
|
| 17 |
D |
L |
-1.8199 |
|
| 18 |
R |
L |
-2.3615 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6208 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7835 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
K |
L |
-2.4064 |
|
| 25 |
S |
L |
0.0000 |
|
| 26 |
S |
L |
-1.8463 |
|
| 27 |
Q |
L |
-1.6855 |
|
| 27A |
S |
L |
-0.7282 |
|
| 27B |
L |
L |
0.0000 |
|
| 27C |
L |
L |
0.2062 |
|
| 27D |
Y |
L |
0.5537 |
|
| 27E |
T |
L |
-0.2924 |
|
| 27F |
S |
L |
-0.4889 |
|
| 28 |
S |
L |
-0.8104 |
|
| 29 |
Q |
L |
-1.2336 |
|
| 30 |
K |
L |
-0.6859 |
|
| 31 |
N |
L |
0.0000 |
|
| 32 |
Y |
L |
0.6321 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.2362 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.4317 |
|
| 39 |
K |
L |
-2.1334 |
|
| 40 |
P |
L |
-1.6237 |
|
| 41 |
G |
L |
-1.5652 |
|
| 42 |
K |
L |
-2.4037 |
|
| 43 |
A |
L |
-1.3368 |
|
| 44 |
P |
L |
-1.1604 |
|
| 45 |
K |
L |
-1.2558 |
|
| 46 |
L |
L |
-0.1855 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.3427 |
|
| 50 |
W |
L |
0.2865 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.5186 |
|
| 53 |
T |
L |
-0.5191 |
|
| 54 |
R |
L |
-1.2270 |
|
| 55 |
E |
L |
-1.2710 |
|
| 56 |
S |
L |
-0.9450 |
|
| 57 |
G |
L |
-0.9168 |
|
| 58 |
V |
L |
0.0000 |
|
| 59 |
P |
L |
-0.6738 |
|
| 60 |
S |
L |
-0.7330 |
|
| 61 |
R |
L |
-0.8690 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.5452 |
|
| 64 |
G |
L |
0.0000 |
|
| 65 |
S |
L |
-0.6614 |
|
| 66 |
G |
L |
-1.1129 |
|
| 67 |
S |
L |
-0.9335 |
|
| 68 |
G |
L |
-0.8623 |
|
| 69 |
T |
L |
-1.5474 |
|
| 70 |
D |
L |
-2.1637 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7574 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6002 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.4516 |
|
| 77 |
S |
L |
-1.1699 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.2824 |
|
| 80 |
P |
L |
-2.2237 |
|
| 81 |
E |
L |
-2.8385 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.1073 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Y |
L |
1.2688 |
|
| 92 |
Y |
L |
1.2016 |
|
| 93 |
A |
L |
0.8572 |
|
| 94 |
Y |
L |
1.2932 |
|
| 95 |
P |
L |
0.7592 |
|
| 96 |
W |
L |
1.2221 |
|
| 97 |
T |
L |
0.5710 |
|
| 98 |
F |
L |
1.0538 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-1.1687 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.5428 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.4551 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.3104 |
|
| 108 |
R |
L |
-0.9459 |
|
| 109 |
T |
L |
-0.1754 |
|
| 110 |
V |
L |
0.0867 |
|
| 111 |
A |
L |
0.0273 |
|
| 112 |
A |
L |
-0.2123 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
0.0604 |
|
| 115 |
V |
L |
0.4888 |
|
| 116 |
F |
L |
1.5309 |
|
| 117 |
I |
L |
1.4139 |
|
| 118 |
F |
L |
1.5588 |
|
| 119 |
P |
L |
-0.1169 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.8639 |
|
| 122 |
D |
L |
-3.2976 |
|
| 123 |
E |
L |
-3.5933 |
|
| 124 |
Q |
L |
-2.8521 |
|
| 125 |
L |
L |
-2.6847 |
|
| 126 |
K |
L |
-3.1446 |
|
| 127 |
S |
L |
-2.0567 |
|
| 128 |
G |
L |
-1.4250 |
|
| 129 |
T |
L |
-1.1449 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0033 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.9431 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.7941 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.4367 |
|
| 138 |
N |
L |
-1.2696 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
-1.2459 |
|
| 141 |
P |
L |
-1.6596 |
|
| 142 |
R |
L |
-2.6546 |
|
| 143 |
E |
L |
-3.1155 |
|
| 144 |
A |
L |
-2.3133 |
|
| 145 |
K |
L |
-2.4800 |
|
| 146 |
V |
L |
-1.1259 |
|
| 147 |
Q |
L |
-0.7034 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5242 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.6687 |
|
| 152 |
N |
L |
-1.4071 |
|
| 153 |
A |
L |
-0.1784 |
|
| 154 |
L |
L |
0.7491 |
|
| 155 |
Q |
L |
-0.2531 |
|
| 156 |
S |
L |
-0.5908 |
|
| 157 |
G |
L |
-1.2736 |
|
| 158 |
N |
L |
-1.4562 |
|
| 159 |
S |
L |
-1.5320 |
|
| 160 |
Q |
L |
-2.1089 |
|
| 161 |
E |
L |
-1.7685 |
|
| 162 |
S |
L |
-1.1422 |
|
| 163 |
V |
L |
-0.7625 |
|
| 164 |
T |
L |
-1.2969 |
|
| 165 |
E |
L |
-2.2259 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.9697 |
|
| 168 |
S |
L |
-3.0432 |
|
| 169 |
K |
L |
-3.2975 |
|
| 170 |
D |
L |
-2.8513 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9681 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.3758 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.4892 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.7179 |
|
| 181 |
L |
L |
-0.9430 |
|
| 182 |
S |
L |
-1.4792 |
|
| 183 |
K |
L |
-2.4025 |
|
| 184 |
A |
L |
-2.1665 |
|
| 185 |
D |
L |
-3.0530 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.5593 |
|
| 188 |
K |
L |
-3.7892 |
|
| 189 |
H |
L |
-3.2420 |
|
| 190 |
K |
L |
-3.2737 |
|
| 191 |
V |
L |
-1.6623 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.8911 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2582 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7469 |
|
| 200 |
G |
L |
-0.4822 |
|
| 201 |
L |
L |
-0.2866 |
|
| 202 |
S |
L |
-0.4628 |
|
| 203 |
S |
L |
-0.4696 |
|
| 204 |
P |
L |
-0.6152 |
|
| 205 |
V |
L |
-0.1437 |
|
| 206 |
T |
L |
-0.5133 |
|
| 207 |
K |
L |
-0.5213 |
|
| 208 |
S |
L |
-0.5908 |
|
| 209 |
F |
L |
-0.9024 |
|
| 210 |
N |
L |
-2.3151 |
|
| 211 |
R |
L |
-2.9686 |
|