Project name: 5wuv:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGYVFTDYGMNWVRQAPGKGLEWMGWINTYIGEPIYADSVKGRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCARGYRSYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8534
• Maximal score value: 2.5268
• Average score: -0.5074
• Total score value: -111.6337

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.2096
2	V	H	-1.3314
3	Q	H	-1.3430
4	L	H	0.0000
5	V	H	0.9623
6	E	H	0.0000
7	S	H	-0.3919
8	G	H	-0.9181
9	G	H	-0.4858
10	G	H	-0.2540
11	L	H	-0.1049
12	V	H	0.0000
13	Q	H	-1.7722
14	P	H	-1.9485
15	G	H	-1.5267
16	G	H	-1.1691
17	S	H	-1.2662
18	L	H	-1.1380
19	R	H	-2.0661
20	L	H	0.0000
21	S	H	-0.3460
22	C	H	0.0000
23	A	H	-0.0816
24	A	H	0.0000
25	S	H	-0.6979
26	G	H	-0.9911
27	Y	H	0.0380
28	V	H	1.2144
29	F	H	0.0000
30	T	H	0.4015
31	D	H	-0.7194
32	Y	H	-0.0478
33	G	H	0.0000
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.1129
39	Q	H	-0.5489
40	A	H	-1.1342
41	P	H	-1.1083
42	G	H	-1.4239
43	K	H	-2.1001
44	G	H	-0.9709
45	L	H	0.5935
46	E	H	-0.0961
47	W	H	0.5389
48	M	H	0.0000
49	G	H	0.0000
50	W	H	0.0000
51	I	H	0.0000
52	N	H	-0.2335
53	T	H	0.0000
54	Y	H	1.5871
55	I	H	1.9994
56	G	H	0.2486
57	E	H	-0.9810
58	P	H	-0.3861
59	I	H	-0.2376
60	Y	H	-0.4674
61	A	H	-1.1109
62	D	H	-2.3823
63	S	H	-1.6573
64	V	H	0.0000
65	K	H	-2.5741
66	G	H	-1.8319
67	R	H	-1.4743
68	F	H	0.0000
69	T	H	-0.8348
70	F	H	0.0000
71	S	H	-0.6675
72	L	H	-0.1806
73	D	H	-1.0951
74	T	H	-0.5784
75	S	H	-1.2222
76	K	H	-2.0056
77	S	H	-0.8116
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.4674
81	L	H	0.0000
82	Q	H	-1.2850
83	M	H	0.0000
84	N	H	-1.2745
85	S	H	-1.2373
86	L	H	0.0000
87	R	H	-2.8534
88	A	H	-1.9877
89	E	H	-2.4049
90	D	H	0.0000
91	T	H	-0.8895
92	A	H	0.0000
93	V	H	0.2547
94	Y	H	0.0000
95	Y	H	0.3821
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	G	H	0.0000
100	Y	H	0.2789
101	R	H	-0.8454
102	S	H	-0.1072
103	Y	H	0.8983
104	A	H	0.3449
105	M	H	-0.0361
106	D	H	-0.9666
107	Y	H	-0.3375
108	W	H	0.1845
109	G	H	0.0000
110	Q	H	-0.7260
111	G	H	-0.1686
112	T	H	-0.0218
113	L	H	0.0246
114	V	H	0.0000
115	T	H	-0.5435
116	V	H	0.0000
117	S	H	-0.9144
118	S	H	-0.7495
119	A	H	-0.4719
120	S	H	-0.5980
121	T	H	-0.9023
122	K	H	-1.1803
123	G	H	-1.4086
124	P	H	0.0000
125	S	H	-0.0612
126	V	H	0.0000
127	F	H	0.9937
128	P	H	-0.0570
129	L	H	0.3512
130	A	H	-0.8541
131	P	H	0.0000
132	S	H	-1.2802
133	S	H	-1.4884
134	K	H	-1.9417
135	S	H	-1.2125
136	T	H	-0.9471
137	S	H	-0.8756
138	G	H	-0.7910
139	G	H	-0.6061
140	T	H	-0.4328
141	A	H	0.0000
142	A	H	0.0792
143	L	H	0.0000
144	G	H	0.0000
145	C	H	0.0000
146	L	H	0.7198
147	V	H	0.0000
148	K	H	-0.1750
149	D	H	-0.5566
150	Y	H	0.0000
151	F	H	0.0000
152	P	H	0.0000
153	E	H	-0.3567
154	P	H	-0.6594
155	V	H	-0.6804
156	T	H	-0.6216
157	V	H	-0.4824
158	S	H	-0.4311
159	W	H	0.0000
160	N	H	-0.8092
161	S	H	-0.6877
162	G	H	-0.5364
163	A	H	-0.2536
164	L	H	-0.0525
165	T	H	-0.3358
166	S	H	-0.3671
167	G	H	-0.4416
168	V	H	-0.1340
169	H	H	-0.6099
170	T	H	0.0894
171	F	H	0.7933
172	P	H	0.6466
173	A	H	1.2806
174	V	H	2.5268
175	L	H	2.1849
176	Q	H	0.7539
177	S	H	0.1195
178	S	H	-0.1871
179	G	H	0.2484
180	L	H	0.4115
181	Y	H	0.9154
182	S	H	0.0000
183	L	H	0.0000
184	S	H	0.6110
185	S	H	0.0000
186	V	H	0.3169
187	V	H	0.0000
188	T	H	-0.2151
189	V	H	0.0000
190	P	H	-0.5915
191	S	H	-0.7565
192	S	H	-0.6714
193	S	H	-0.5911
194	L	H	-0.7852
195	G	H	-1.2521
196	T	H	-0.8728
197	Q	H	-1.1711
198	T	H	-1.1032
199	Y	H	0.0000
200	I	H	-1.4207
201	C	H	0.0000
202	N	H	-1.5843
203	V	H	0.0000
204	N	H	-2.1710
205	H	H	0.0000
206	K	H	-2.7856
207	P	H	-1.5803
208	S	H	-1.8088
209	N	H	-2.5930
210	T	H	-2.1328
211	K	H	-2.7998
212	V	H	-1.8359
213	D	H	-2.6643
214	K	H	-2.1075
215	K	H	-2.4729
216	V	H	0.0000
217	E	H	-2.7424
218	P	H	-1.9021
219	K	H	-2.3679
220	S	H	-1.3082