Project name: 5y9j:H

Chain sequence(s)	H: VQLQQSGAEVKKPGSSVRVSCKASGGTFNNNAINWVRQAPGQGLEWMGGIIPMFGTAKYSQNFQGRVAITADESTGTASMELSSLRSEDTAVYYCARSRDLLLFPHHALSPWGRGTMVTVSSASTKGPSVFPLAPSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7523
• Maximal score value: 2.8855
• Average score: -0.5765
• Total score value: -125.67

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	1.0352
3	Q	H	-1.1459
4	L	H	0.0000
5	Q	H	-2.4600
6	Q	H	-1.6251
7	S	H	-1.3956
8	G	H	-1.0976
9	A	H	-0.8073
10	E	H	-1.3755
11	V	H	-0.8924
12	K	H	-1.8034
13	K	H	-2.4443
14	P	H	-2.0994
15	G	H	-1.4829
16	S	H	-1.2424
17	S	H	-1.4882
18	V	H	0.0000
19	R	H	-2.3948
20	V	H	0.0000
21	S	H	-1.2328
22	C	H	0.0000
23	K	H	-2.3304
24	A	H	-1.4922
25	S	H	-1.2033
26	G	H	-0.9272
27	G	H	-1.3296
28	T	H	-1.6826
29	F	H	0.0000
30	N	H	-1.9552
31	N	H	-1.2281
32	N	H	-0.7524
33	A	H	0.0000
34	I	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.3653
39	Q	H	-0.6532
40	A	H	-1.1162
41	P	H	-1.2053
42	G	H	-1.1766
43	Q	H	-1.6889
44	G	H	-0.9052
45	L	H	0.2641
46	E	H	-0.9825
47	W	H	-0.0238
48	M	H	0.0000
49	G	H	0.0000
50	G	H	0.0000
51	I	H	0.1603
52	I	H	-0.0605
53	P	H	-0.6294
54	M	H	-0.0461
55	F	H	1.0154
56	G	H	0.1205
57	T	H	-0.1824
58	A	H	-0.4750
59	K	H	-1.4106
60	Y	H	-0.5322
61	S	H	-1.2709
62	Q	H	-2.1830
63	N	H	-2.2887
64	F	H	0.0000
65	Q	H	-2.1268
66	G	H	-1.4661
67	R	H	-1.1955
68	V	H	-1.0901
69	A	H	-0.6926
70	I	H	0.0000
71	T	H	-0.6123
72	A	H	-1.2153
73	D	H	-2.4335
74	E	H	-2.6056
75	S	H	-1.6801
76	T	H	-1.4796
77	G	H	0.0000
78	T	H	-1.7051
79	A	H	0.0000
80	S	H	0.0000
81	M	H	0.0000
82	E	H	-1.7929
83	L	H	0.0000
84	S	H	-1.2291
85	S	H	-1.1885
86	L	H	0.0000
87	R	H	-2.7360
88	S	H	-2.2547
89	E	H	-2.4887
90	D	H	0.0000
91	T	H	-1.0987
92	A	H	0.0000
93	V	H	0.1271
94	Y	H	0.0000
95	Y	H	-0.2422
96	C	H	0.0000
97	A	H	0.0000
98	R	H	-0.1335
99	S	H	-0.3257
100	R	H	-0.4062
101	D	H	0.9038
102	L	H	2.2535
103	L	H	2.8855
104	L	H	2.5042
105	F	H	1.3405
106	P	H	0.5940
107	H	H	-0.8820
108	H	H	-1.0537
109	A	H	-0.6484
110	L	H	0.0151
111	S	H	-0.1201
112	P	H	-0.0302
113	W	H	-0.2106
114	G	H	0.0000
115	R	H	-2.0789
116	G	H	-1.0262
117	T	H	0.0000
118	M	H	-0.1326
119	V	H	0.0000
120	T	H	-0.7519
121	V	H	0.0000
122	S	H	-1.3391
123	S	H	-1.0131
124	A	H	-0.6465
125	S	H	-0.7773
126	T	H	-0.8686
127	K	H	-1.4199
128	G	H	-1.6198
129	P	H	0.0000
130	S	H	-0.3339
131	V	H	0.0000
132	F	H	0.4469
133	P	H	0.0036
134	L	H	0.2527
135	A	H	-0.8468
136	P	H	0.0000
137	S	H	-0.4751
143	G	H	-0.8082
144	G	H	-0.8256
145	T	H	-0.5577
146	A	H	0.0000
147	A	H	0.1243
148	L	H	0.0000
149	G	H	0.0000
150	C	H	0.0000
151	L	H	0.6420
152	V	H	0.0000
153	K	H	-0.4525
154	D	H	-0.6116
155	Y	H	0.0000
156	F	H	0.0000
157	P	H	0.0000
158	E	H	-0.4484
159	P	H	-0.6679
160	V	H	-0.5547
161	T	H	-0.4401
162	V	H	-0.2162
163	S	H	-0.4028
164	W	H	0.0000
165	N	H	-0.6978
166	S	H	-0.6162
167	G	H	-0.5490
168	A	H	-0.2377
169	L	H	0.0231
170	T	H	-0.2731
171	S	H	-0.3367
172	G	H	-0.4086
173	V	H	0.0599
174	H	H	-0.3617
175	T	H	0.2783
176	F	H	1.2121
177	P	H	0.8471
178	A	H	1.3251
179	V	H	2.4309
180	L	H	2.0676
181	Q	H	0.6167
182	S	H	0.0296
183	S	H	-0.2633
184	G	H	0.1647
185	L	H	0.1636
186	Y	H	0.6983
187	S	H	0.6503
188	L	H	0.0000
189	S	H	0.7121
190	S	H	0.0000
191	V	H	0.5151
192	V	H	0.0000
193	T	H	-0.2172
194	V	H	0.0000
195	P	H	-0.6565
196	S	H	-0.6112
197	S	H	-0.7052
198	S	H	-0.6079
199	L	H	-0.8127
200	G	H	-0.9816
201	T	H	-0.7282
202	Q	H	-1.2929
203	T	H	-1.0588
204	Y	H	0.0000
205	I	H	-1.0796
206	C	H	0.0000
207	N	H	0.0000
208	V	H	0.0000
209	N	H	-1.7405
210	H	H	0.0000
211	K	H	-2.5672
212	P	H	-1.6727
213	S	H	-1.8032
214	N	H	-2.4585
215	T	H	-2.0269
216	K	H	-2.5908
217	V	H	-1.6062
218	D	H	-2.4636
219	K	H	-2.0452
220	K	H	-2.3607
221	V	H	0.0000
222	E	H	-2.7523
223	P	H	-1.8438
224	K	H	-2.1821