Project name: 5jq6:L
Status: done
submitted: 2019-03-20 20:33:13, status changed: 2019-03-20 20:44:47
Settings
|
Chain sequence(s)
|
L: DIVMTQSPDSLAVSLGERVTMNCKSSQSVLYSSNQKNYLAWYQQKPGQSPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSVQAEDLAVYYCHQYLSSYTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGPVTKSANR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.1938
-
Maximal score value
-
2.4845
-
Average score
-
-0.8358
-
Total score value
-
-177.1946
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.3846 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
V |
L |
1.2891 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.2971 |
|
| 6 |
Q |
L |
-0.9167 |
|
| 7 |
S |
L |
-1.1220 |
|
| 8 |
P |
L |
-1.2733 |
|
| 9 |
D |
L |
-2.2142 |
|
| 10 |
S |
L |
-1.2771 |
|
| 11 |
L |
L |
-0.6021 |
|
| 12 |
A |
L |
-0.4659 |
|
| 13 |
V |
L |
0.0000 |
|
| 14 |
S |
L |
-0.6856 |
|
| 15 |
L |
L |
0.3571 |
|
| 16 |
G |
L |
-0.8020 |
|
| 17 |
E |
L |
-1.8622 |
|
| 18 |
R |
L |
-2.3535 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6580 |
|
| 21 |
M |
L |
0.0000 |
|
| 22 |
N |
L |
-1.0808 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
K |
L |
-1.6997 |
|
| 25 |
S |
L |
0.0000 |
|
| 26 |
S |
L |
-0.8736 |
|
| 27 |
Q |
L |
-1.5301 |
|
| 28 |
S |
L |
-0.7920 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
L |
L |
0.0239 |
|
| 31 |
Y |
L |
0.5178 |
|
| 32 |
S |
L |
-0.4451 |
|
| 33 |
S |
L |
-0.7666 |
|
| 34 |
N |
L |
-1.4394 |
|
| 35 |
Q |
L |
-1.6854 |
|
| 36 |
K |
L |
-1.1516 |
|
| 37 |
N |
L |
-0.2386 |
|
| 38 |
Y |
L |
0.4455 |
|
| 39 |
L |
L |
0.0000 |
|
| 40 |
A |
L |
0.0000 |
|
| 41 |
W |
L |
0.0000 |
|
| 42 |
Y |
L |
0.1228 |
|
| 43 |
Q |
L |
0.0000 |
|
| 44 |
Q |
L |
-1.2157 |
|
| 45 |
K |
L |
-1.5853 |
|
| 46 |
P |
L |
-1.1028 |
|
| 47 |
G |
L |
-1.4120 |
|
| 48 |
Q |
L |
-2.0582 |
|
| 49 |
S |
L |
-1.4754 |
|
| 50 |
P |
L |
-1.3449 |
|
| 51 |
K |
L |
-1.6674 |
|
| 52 |
L |
L |
-0.5364 |
|
| 53 |
L |
L |
0.0000 |
|
| 54 |
I |
L |
0.0000 |
|
| 55 |
Y |
L |
0.3920 |
|
| 56 |
W |
L |
0.3164 |
|
| 57 |
A |
L |
0.0000 |
|
| 58 |
S |
L |
-0.4458 |
|
| 59 |
T |
L |
-0.4764 |
|
| 60 |
R |
L |
-1.3635 |
|
| 61 |
E |
L |
-1.1242 |
|
| 62 |
S |
L |
-0.8006 |
|
| 63 |
G |
L |
-0.9281 |
|
| 64 |
V |
L |
-1.0603 |
|
| 65 |
P |
L |
-1.2967 |
|
| 66 |
D |
L |
-2.1651 |
|
| 67 |
R |
L |
-1.5586 |
|
| 68 |
F |
L |
0.0000 |
|
| 69 |
S |
L |
-0.9308 |
|
| 70 |
G |
L |
0.0000 |
|
| 71 |
S |
L |
-0.6632 |
|
| 72 |
G |
L |
-1.1380 |
|
| 73 |
S |
L |
-1.1145 |
|
| 74 |
G |
L |
-0.9776 |
|
| 75 |
T |
L |
-1.5237 |
|
| 76 |
D |
L |
-2.2007 |
|
| 77 |
F |
L |
0.0000 |
|
| 78 |
T |
L |
-0.7784 |
|
| 79 |
L |
L |
0.0000 |
|
| 80 |
T |
L |
-0.6152 |
|
| 81 |
I |
L |
0.0000 |
|
| 82 |
S |
L |
-1.6178 |
|
| 83 |
S |
L |
-1.5027 |
|
| 84 |
V |
L |
0.0000 |
|
| 85 |
Q |
L |
-1.2361 |
|
| 86 |
A |
L |
-0.8475 |
|
| 87 |
E |
L |
-2.0468 |
|
| 88 |
D |
L |
0.0000 |
|
| 89 |
L |
L |
-0.4500 |
|
| 90 |
A |
L |
0.0000 |
|
| 91 |
V |
L |
-0.3739 |
|
| 92 |
Y |
L |
0.0000 |
|
| 93 |
Y |
L |
0.3760 |
|
| 94 |
C |
L |
0.0000 |
|
| 95 |
H |
L |
0.0000 |
|
| 96 |
Q |
L |
0.0000 |
|
| 97 |
Y |
L |
1.2190 |
|
| 98 |
L |
L |
0.8808 |
|
| 99 |
S |
L |
0.0275 |
|
| 100 |
S |
L |
0.2518 |
|
| 101 |
Y |
L |
1.7118 |
|
| 102 |
T |
L |
1.7036 |
|
| 103 |
F |
L |
2.4845 |
|
| 104 |
G |
L |
0.8349 |
|
| 105 |
G |
L |
-0.4530 |
|
| 106 |
G |
L |
-0.5640 |
|
| 107 |
T |
L |
0.0000 |
|
| 108 |
K |
L |
-1.1721 |
|
| 109 |
L |
L |
0.0000 |
|
| 110 |
E |
L |
-0.5968 |
|
| 111 |
I |
L |
-0.5941 |
|
| 112 |
K |
L |
-1.3221 |
|
| 113 |
R |
L |
-1.2028 |
|
| 114 |
T |
L |
-0.2332 |
|
| 115 |
V |
L |
0.4080 |
|
| 116 |
A |
L |
-0.1062 |
|
| 117 |
A |
L |
-0.5245 |
|
| 118 |
P |
L |
-0.4533 |
|
| 119 |
S |
L |
-0.1103 |
|
| 120 |
V |
L |
0.0000 |
|
| 121 |
F |
L |
1.8436 |
|
| 122 |
I |
L |
1.8556 |
|
| 123 |
F |
L |
2.3817 |
|
| 124 |
P |
L |
0.2709 |
|
| 125 |
P |
L |
-0.7451 |
|
| 126 |
S |
L |
-1.8191 |
|
| 127 |
D |
L |
-3.4531 |
|
| 128 |
E |
L |
-3.8256 |
|
| 129 |
Q |
L |
-3.4422 |
|
| 130 |
L |
L |
-2.8396 |
|
| 131 |
K |
L |
-3.3142 |
|
| 132 |
S |
L |
-2.1862 |
|
| 133 |
G |
L |
-1.6495 |
|
| 134 |
T |
L |
-1.2891 |
|
| 135 |
A |
L |
0.0000 |
|
| 136 |
S |
L |
-0.0185 |
|
| 137 |
V |
L |
0.0000 |
|
| 138 |
V |
L |
1.0889 |
|
| 139 |
C |
L |
0.0000 |
|
| 140 |
L |
L |
0.7804 |
|
| 141 |
L |
L |
0.0000 |
|
| 142 |
N |
L |
-0.7894 |
|
| 143 |
N |
L |
-2.1441 |
|
| 144 |
F |
L |
0.0000 |
|
| 145 |
Y |
L |
0.0000 |
|
| 146 |
P |
L |
-1.8864 |
|
| 147 |
R |
L |
-3.0620 |
|
| 148 |
E |
L |
-3.3137 |
|
| 149 |
A |
L |
-2.4946 |
|
| 150 |
K |
L |
-2.3799 |
|
| 151 |
V |
L |
-1.0531 |
|
| 152 |
Q |
L |
-0.6119 |
|
| 153 |
W |
L |
0.0000 |
|
| 154 |
K |
L |
-0.4011 |
|
| 155 |
V |
L |
-0.3855 |
|
| 157 |
N |
L |
-0.9070 |
|
| 158 |
A |
L |
-0.0026 |
|
| 159 |
L |
L |
0.9003 |
|
| 160 |
Q |
L |
-0.2573 |
|
| 161 |
S |
L |
-0.5663 |
|
| 162 |
G |
L |
-1.3081 |
|
| 163 |
N |
L |
-1.8888 |
|
| 164 |
S |
L |
-1.8963 |
|
| 165 |
Q |
L |
-2.5099 |
|
| 166 |
E |
L |
-2.3696 |
|
| 167 |
S |
L |
-1.3980 |
|
| 168 |
V |
L |
-0.8894 |
|
| 169 |
T |
L |
-1.4089 |
|
| 170 |
E |
L |
-2.1870 |
|
| 171 |
Q |
L |
-2.4819 |
|
| 172 |
D |
L |
-2.9692 |
|
| 173 |
S |
L |
-2.2774 |
|
| 174 |
K |
L |
-3.0377 |
|
| 175 |
D |
L |
-3.2740 |
|
| 176 |
S |
L |
-2.6515 |
|
| 177 |
T |
L |
0.0000 |
|
| 178 |
Y |
L |
0.0000 |
|
| 179 |
S |
L |
-1.3125 |
|
| 180 |
L |
L |
0.0000 |
|
| 181 |
S |
L |
-0.4522 |
|
| 182 |
S |
L |
0.0000 |
|
| 183 |
T |
L |
-0.7163 |
|
| 184 |
L |
L |
0.0000 |
|
| 185 |
T |
L |
-0.8394 |
|
| 186 |
L |
L |
-1.0766 |
|
| 187 |
S |
L |
-1.3410 |
|
| 188 |
K |
L |
-2.5938 |
|
| 189 |
A |
L |
-2.3252 |
|
| 190 |
D |
L |
-3.0850 |
|
| 191 |
Y |
L |
0.0000 |
|
| 192 |
E |
L |
-4.1938 |
|
| 193 |
K |
L |
-4.1062 |
|
| 194 |
H |
L |
-3.5840 |
|
| 195 |
K |
L |
-3.5308 |
|
| 196 |
V |
L |
-1.6457 |
|
| 197 |
Y |
L |
0.0000 |
|
| 198 |
A |
L |
0.0000 |
|
| 199 |
C |
L |
0.0000 |
|
| 200 |
E |
L |
-0.9855 |
|
| 201 |
V |
L |
0.0000 |
|
| 202 |
T |
L |
-1.2270 |
|
| 203 |
H |
L |
-1.7357 |
|
| 204 |
Q |
L |
-1.7974 |
|
| 205 |
G |
L |
-0.7927 |
|
| 209 |
P |
L |
-0.4052 |
|
| 210 |
V |
L |
0.2683 |
|
| 211 |
T |
L |
-0.2612 |
|
| 212 |
K |
L |
-0.1858 |
|
| 213 |
S |
L |
-0.4660 |
|
| 214 |
A |
L |
-1.0494 |
|
| 215 |
N |
L |
-2.5851 |
|
| 216 |
R |
L |
-3.6846 |
|