Project name: aquaporin

Chain sequence(s)	A: KLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.3972
• Maximal score value: 3.6996
• Average score: 0.4173
• Total score value: 94.3153

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
8	K	A	-0.8273
9	L	A	0.7945
10	F	A	0.9174
11	W	A	0.7093
12	R	A	-0.4686
13	A	A	0.0000
14	V	A	0.0000
15	V	A	1.6705
16	A	A	0.9466
17	E	A	0.0000
18	F	A	2.4311
19	L	A	2.5724
20	A	A	0.0000
21	T	A	0.0000
22	T	A	2.2701
23	L	A	2.2969
24	F	A	0.0000
25	V	A	0.0000
26	F	A	1.8687
27	I	A	1.2242
28	S	A	0.0000
29	I	A	0.0000
30	G	A	0.4709
31	S	A	0.3779
32	A	A	-0.0606
33	L	A	0.0000
34	G	A	0.5760
35	F	A	0.8222
36	K	A	0.2152
37	Y	A	1.0219
38	P	A	0.6227
39	V	A	0.9289
40	G	A	-0.4815
41	N	A	-1.6884
42	N	A	-2.0084
43	Q	A	-1.7757
44	T	A	-0.6468
45	A	A	-0.2075
46	V	A	0.5926
47	Q	A	-0.4479
48	D	A	-1.7519
49	N	A	-0.6828
50	V	A	0.7276
51	K	A	0.1805
52	V	A	0.0000
53	S	A	0.0000
54	L	A	1.4939
55	A	A	0.8684
56	F	A	0.0000
57	G	A	0.0000
58	L	A	1.6287
59	S	A	1.1764
60	I	A	0.7732
61	A	A	0.0000
62	T	A	0.1066
63	L	A	0.0000
64	A	A	0.0000
65	Q	A	-1.3015
66	S	A	-0.8262
67	V	A	-0.2066
68	G	A	-0.4026
69	H	A	-0.8788
70	I	A	0.6270
71	S	A	0.4571
72	G	A	0.1862
73	A	A	0.0000
74	H	A	-0.3714
75	L	A	0.0000
76	N	A	0.0000
77	P	A	0.0000
78	A	A	0.0000
79	V	A	0.0000
80	T	A	0.0000
81	L	A	1.2925
82	G	A	0.0000
83	L	A	1.5028
84	L	A	1.5433
85	L	A	1.5128
86	S	A	0.6184
87	C	A	0.6501
88	Q	A	0.6819
89	I	A	2.0034
90	S	A	1.2144
91	I	A	2.0089
92	F	A	1.4601
93	R	A	-0.0148
94	A	A	0.0000
95	L	A	1.7934
96	M	A	1.5503
97	Y	A	1.7983
98	I	A	2.1726
99	I	A	2.9895
100	A	A	0.0000
101	Q	A	0.0000
102	C	A	2.1893
103	V	A	2.4496
104	G	A	0.0000
105	A	A	0.0000
106	I	A	2.4059
107	V	A	2.8298
108	A	A	0.0000
109	T	A	0.0000
110	A	A	2.1951
111	I	A	2.8372
112	L	A	0.0000
113	S	A	0.9421
114	G	A	1.0324
115	I	A	2.0870
116	T	A	1.0326
117	S	A	0.2537
118	S	A	0.1553
119	L	A	0.4588
120	T	A	-0.1289
121	G	A	-0.6658
122	N	A	-1.3215
123	S	A	-0.7818
124	L	A	-0.0888
125	G	A	-0.7794
126	R	A	-1.8594
127	N	A	-1.2436
128	D	A	-1.2962
129	L	A	0.0000
130	A	A	0.0000
131	D	A	-1.6510
132	G	A	-0.3759
133	V	A	1.2731
134	N	A	-0.1869
135	S	A	-0.6831
136	G	A	-1.1703
137	Q	A	-1.2898
138	G	A	0.0000
139	L	A	0.5043
140	G	A	0.4971
141	I	A	1.0373
142	E	A	0.0000
143	I	A	1.9886
144	I	A	2.2707
145	G	A	1.2688
146	T	A	0.0000
147	L	A	1.1436
148	Q	A	0.1279
149	L	A	0.0000
150	V	A	0.0000
151	L	A	0.4258
152	C	A	0.2192
153	V	A	0.0000
154	L	A	0.0088
155	A	A	-0.5559
156	T	A	-1.2657
157	T	A	-2.2144
158	D	A	-3.5414
159	R	A	-4.0322
160	R	A	-4.3972
161	R	A	-3.6296
162	R	A	-1.9507
163	D	A	-1.4506
164	L	A	0.6362
165	G	A	-0.0559
166	G	A	-0.2256
167	S	A	0.0132
168	A	A	-0.1726
169	P	A	0.0000
170	L	A	1.6012
171	A	A	1.0923
172	I	A	1.0633
173	G	A	0.0000
174	L	A	1.7516
175	S	A	1.0609
176	V	A	0.0000
177	A	A	0.0000
178	L	A	2.2821
179	G	A	1.5724
180	H	A	0.0000
181	L	A	1.8834
182	L	A	2.0677
183	A	A	0.0000
184	I	A	0.3287
185	D	A	-0.7643
186	Y	A	0.4037
187	T	A	0.0000
188	G	A	-0.5425
189	C	A	0.0000
190	G	A	0.0000
191	I	A	0.0000
192	N	A	-0.0094
193	P	A	0.8710
194	A	A	0.0000
195	R	A	0.0000
196	S	A	1.0758
197	F	A	2.7037
198	G	A	0.0000
199	S	A	0.0000
200	A	A	0.0000
201	V	A	2.5644
202	I	A	2.2805
203	T	A	0.2841
204	H	A	-0.9871
205	N	A	-1.6022
206	F	A	-0.5604
207	S	A	-0.0692
208	N	A	-0.0192
209	H	A	0.5327
210	W	A	2.0177
211	I	A	1.5715
212	F	A	0.0000
213	W	A	1.7998
214	V	A	2.3126
215	G	A	0.0000
216	P	A	0.0000
217	F	A	2.0276
218	I	A	2.5237
219	G	A	0.0000
220	G	A	0.0000
221	A	A	1.9762
222	L	A	1.8369
223	A	A	0.0000
224	V	A	0.0000
225	L	A	2.6142
226	I	A	2.7376
227	Y	A	2.2269
228	D	A	1.6656
229	F	A	3.3980
230	I	A	3.6996
231	L	A	2.9189
232	A	A	1.4038
233	P	A	0.1513