Project name: 5etu:A
Status: done
submitted: 2019-03-20 20:25:38, status changed: 2019-03-20 20:38:26
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8485
-
Maximal score value
-
1.7139
-
Average score
-
-0.8585
-
Total score value
-
-182.8687
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.3078 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7844 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.2144 |
|
| 6 |
Q |
A |
-0.1420 |
|
| 7 |
S |
A |
-0.0295 |
|
| 8 |
P |
A |
0.7352 |
|
| 9 |
V |
A |
1.7139 |
|
| 10 |
I |
A |
1.0790 |
|
| 11 |
L |
A |
0.4138 |
|
| 12 |
S |
A |
-0.4176 |
|
| 13 |
V |
A |
-1.2957 |
|
| 14 |
S |
A |
-1.8149 |
|
| 15 |
P |
A |
-2.0440 |
|
| 16 |
G |
A |
-2.2652 |
|
| 17 |
E |
A |
-2.9598 |
|
| 18 |
R |
A |
-3.0632 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7134 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.6997 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.3341 |
|
| 25 |
A |
A |
-1.1914 |
|
| 26 |
S |
A |
-0.9207 |
|
| 27 |
Q |
A |
-1.2653 |
|
| 28 |
S |
A |
-1.4668 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0342 |
|
| 31 |
T |
A |
-0.7238 |
|
| 32 |
N |
A |
-1.0594 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.0929 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.5264 |
|
| 39 |
R |
A |
-2.1663 |
|
| 40 |
T |
A |
-1.8441 |
|
| 41 |
N |
A |
-1.9422 |
|
| 42 |
G |
A |
-1.5406 |
|
| 43 |
S |
A |
-1.0938 |
|
| 44 |
P |
A |
-1.0486 |
|
| 45 |
R |
A |
-0.9037 |
|
| 46 |
L |
A |
-0.1586 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.8358 |
|
| 50 |
Y |
A |
-0.2605 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1348 |
|
| 53 |
E |
A |
-1.9207 |
|
| 54 |
S |
A |
-1.1017 |
|
| 55 |
I |
A |
-0.4740 |
|
| 56 |
S |
A |
-0.2149 |
|
| 57 |
G |
A |
-0.3863 |
|
| 58 |
I |
A |
-0.1385 |
|
| 59 |
P |
A |
-0.2838 |
|
| 60 |
S |
A |
-0.5291 |
|
| 61 |
R |
A |
-1.1310 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.8935 |
|
| 64 |
G |
A |
-0.6790 |
|
| 65 |
S |
A |
-0.6937 |
|
| 66 |
G |
A |
-0.8703 |
|
| 67 |
S |
A |
-0.9551 |
|
| 68 |
G |
A |
-1.2247 |
|
| 69 |
T |
A |
-1.6848 |
|
| 70 |
D |
A |
-2.0850 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.7581 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.8523 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.3757 |
|
| 77 |
S |
A |
-2.3900 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.9741 |
|
| 80 |
S |
A |
-2.8363 |
|
| 81 |
E |
A |
-2.9170 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-1.9020 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.9730 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1153 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.1313 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.4220 |
|
| 92 |
N |
A |
-1.8201 |
|
| 93 |
N |
A |
-1.2440 |
|
| 94 |
W |
A |
0.0290 |
|
| 95 |
P |
A |
-0.1643 |
|
| 96 |
T |
A |
-0.5018 |
|
| 97 |
T |
A |
0.2980 |
|
| 98 |
F |
A |
1.4418 |
|
| 99 |
G |
A |
0.6352 |
|
| 100 |
A |
A |
0.5769 |
|
| 101 |
G |
A |
0.2738 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.5506 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.1549 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.5274 |
|
| 108 |
R |
A |
-1.1695 |
|
| 109 |
T |
A |
-0.0422 |
|
| 110 |
V |
A |
0.5238 |
|
| 111 |
A |
A |
0.1296 |
|
| 112 |
A |
A |
-0.1814 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1315 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.3420 |
|
| 117 |
I |
A |
1.3386 |
|
| 118 |
F |
A |
1.6261 |
|
| 119 |
P |
A |
0.0542 |
|
| 120 |
P |
A |
-0.6844 |
|
| 121 |
S |
A |
-1.7605 |
|
| 122 |
D |
A |
-3.2117 |
|
| 123 |
E |
A |
-3.4003 |
|
| 124 |
Q |
A |
-2.5034 |
|
| 125 |
L |
A |
-2.5833 |
|
| 126 |
K |
A |
-2.9928 |
|
| 127 |
S |
A |
-1.8566 |
|
| 128 |
G |
A |
-1.5077 |
|
| 129 |
T |
A |
-1.1987 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0390 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7843 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.7389 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.5537 |
|
| 138 |
N |
A |
-1.3811 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
0.0000 |
|
| 141 |
P |
A |
-1.6963 |
|
| 142 |
R |
A |
-2.8602 |
|
| 143 |
E |
A |
-3.2129 |
|
| 144 |
A |
A |
-2.3513 |
|
| 145 |
K |
A |
-2.2893 |
|
| 146 |
V |
A |
-1.1921 |
|
| 147 |
Q |
A |
-0.8111 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.6535 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.8905 |
|
| 152 |
N |
A |
-1.5227 |
|
| 153 |
A |
A |
-0.2834 |
|
| 154 |
L |
A |
0.6807 |
|
| 155 |
Q |
A |
-0.2078 |
|
| 156 |
S |
A |
-0.4673 |
|
| 157 |
G |
A |
-1.0811 |
|
| 158 |
N |
A |
-1.1109 |
|
| 159 |
S |
A |
-1.5138 |
|
| 160 |
Q |
A |
-2.3352 |
|
| 161 |
E |
A |
-2.3732 |
|
| 162 |
S |
A |
-1.3322 |
|
| 163 |
V |
A |
-0.7809 |
|
| 164 |
T |
A |
-1.2157 |
|
| 165 |
E |
A |
-2.4846 |
|
| 166 |
Q |
A |
-2.2797 |
|
| 167 |
D |
A |
-2.5284 |
|
| 168 |
S |
A |
-2.7535 |
|
| 169 |
K |
A |
-3.0289 |
|
| 170 |
D |
A |
-2.3064 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
-1.5978 |
|
| 174 |
S |
A |
-0.9785 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4393 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5726 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.5839 |
|
| 181 |
L |
A |
-0.8356 |
|
| 182 |
S |
A |
-1.2252 |
|
| 183 |
K |
A |
-2.3721 |
|
| 184 |
A |
A |
-2.1309 |
|
| 185 |
D |
A |
-2.8283 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.8485 |
|
| 188 |
K |
A |
-3.8242 |
|
| 189 |
H |
A |
-3.1458 |
|
| 190 |
K |
A |
-3.1452 |
|
| 191 |
V |
A |
-1.4044 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
-0.8214 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.9074 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2582 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.6981 |
|
| 200 |
G |
A |
-0.3495 |
|
| 201 |
L |
A |
-0.1557 |
|
| 202 |
S |
A |
-0.4299 |
|
| 203 |
S |
A |
-0.4114 |
|
| 204 |
P |
A |
-0.5920 |
|
| 205 |
V |
A |
-0.0421 |
|
| 206 |
T |
A |
-0.3741 |
|
| 207 |
K |
A |
-0.3237 |
|
| 208 |
S |
A |
-0.3672 |
|
| 209 |
F |
A |
-0.5718 |
|
| 210 |
N |
A |
-1.6861 |
|
| 211 |
R |
A |
-2.3642 |
|
| 212 |
G |
A |
-1.4171 |
|
| 213 |
A |
A |
-0.7887 |
|