Project name: 3gkw:H
Status: done
submitted: 2019-03-20 15:33:38, status changed: 2019-03-20 17:16:32
Settings
|
Chain sequence(s)
|
H: QSGAEVKKPGSSVKVSCKASGYTFTNYYIYWVRQAPGQGLEWIGGINPTSGGSNFNEKFKTRVTITADESSTTAYMELSSLRSEDTAFYFCTRQGLWFDSDGRGFDFWGQGTTVTVSSASTKGPSVFPLAPAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPQTYICNVNHKPSNTKVDKKVP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4726
-
Maximal score value
-
2.3176
-
Average score
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-0.6598
-
Total score value
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-133.2879
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 6 |
Q |
H |
-1.6401 |
|
| 7 |
S |
H |
-1.1661 |
|
| 8 |
G |
H |
-1.1427 |
|
| 9 |
A |
H |
0.0000 |
|
| 10 |
E |
H |
-1.3911 |
|
| 11 |
V |
H |
-1.0580 |
|
| 12 |
K |
H |
-1.8233 |
|
| 13 |
K |
H |
-2.4483 |
|
| 14 |
P |
H |
-2.0819 |
|
| 15 |
G |
H |
-1.5165 |
|
| 16 |
S |
H |
-1.2048 |
|
| 17 |
S |
H |
-1.3135 |
|
| 18 |
V |
H |
0.0000 |
|
| 19 |
K |
H |
-1.9280 |
|
| 20 |
V |
H |
0.0000 |
|
| 21 |
S |
H |
-0.9942 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
K |
H |
-1.9559 |
|
| 24 |
A |
H |
0.0000 |
|
| 25 |
S |
H |
-0.5071 |
|
| 26 |
G |
H |
-0.2628 |
|
| 27 |
Y |
H |
0.9810 |
|
| 28 |
T |
H |
0.0000 |
|
| 29 |
F |
H |
0.0000 |
|
| 30 |
T |
H |
-0.0521 |
|
| 31 |
N |
H |
0.3956 |
|
| 32 |
Y |
H |
0.0000 |
|
| 33 |
Y |
H |
-0.1919 |
|
| 34 |
I |
H |
0.0000 |
|
| 35 |
Y |
H |
-0.0741 |
|
| 36 |
W |
H |
0.0000 |
|
| 37 |
V |
H |
0.0000 |
|
| 38 |
R |
H |
0.0000 |
|
| 39 |
Q |
H |
-0.3756 |
|
| 40 |
A |
H |
-0.9901 |
|
| 41 |
P |
H |
-1.1723 |
|
| 42 |
G |
H |
-1.3202 |
|
| 43 |
Q |
H |
-1.5593 |
|
| 44 |
G |
H |
-0.6685 |
|
| 45 |
L |
H |
0.7980 |
|
| 46 |
E |
H |
0.1467 |
|
| 47 |
W |
H |
0.4103 |
|
| 48 |
I |
H |
0.0000 |
|
| 49 |
G |
H |
0.0000 |
|
| 50 |
G |
H |
0.0000 |
|
| 51 |
I |
H |
0.0000 |
|
| 52 |
N |
H |
-0.6701 |
|
| 52A |
P |
H |
0.0000 |
|
| 53 |
T |
H |
-0.6965 |
|
| 54 |
S |
H |
-0.6770 |
|
| 55 |
G |
H |
-1.1819 |
|
| 56 |
G |
H |
-1.0634 |
|
| 57 |
S |
H |
-0.9275 |
|
| 58 |
N |
H |
-1.5967 |
|
| 59 |
F |
H |
-1.4063 |
|
| 60 |
N |
H |
-2.1087 |
|
| 61 |
E |
H |
-3.4726 |
|
| 62 |
K |
H |
-3.0989 |
|
| 63 |
F |
H |
0.0000 |
|
| 64 |
K |
H |
-3.1060 |
|
| 65 |
T |
H |
-1.6173 |
|
| 66 |
R |
H |
-1.4242 |
|
| 67 |
V |
H |
0.0000 |
|
| 68 |
T |
H |
-0.8025 |
|
| 69 |
I |
H |
0.0000 |
|
| 70 |
T |
H |
-0.6132 |
|
| 71 |
A |
H |
-1.2656 |
|
| 72 |
D |
H |
-2.1985 |
|
| 73 |
E |
H |
-2.6302 |
|
| 74 |
S |
H |
-1.5601 |
|
| 75 |
S |
H |
-1.4876 |
|
| 76 |
T |
H |
-1.6044 |
|
| 77 |
T |
H |
-1.5385 |
|
| 78 |
A |
H |
0.0000 |
|
| 79 |
Y |
H |
-0.6356 |
|
| 80 |
M |
H |
0.0000 |
|
| 81 |
E |
H |
-1.3150 |
|
| 82 |
L |
H |
0.0000 |
|
| 82A |
S |
H |
-0.9504 |
|
| 82B |
S |
H |
-1.0812 |
|
| 82C |
L |
H |
0.0000 |
|
| 83 |
R |
H |
-2.5692 |
|
| 84 |
S |
H |
-2.1787 |
|
| 85 |
E |
H |
-2.4007 |
|
| 86 |
D |
H |
0.0000 |
|
| 87 |
T |
H |
-1.0274 |
|
| 88 |
A |
H |
0.0000 |
|
| 89 |
F |
H |
0.2321 |
|
| 90 |
Y |
H |
0.0000 |
|
| 91 |
F |
H |
0.0000 |
|
| 92 |
C |
H |
0.0000 |
|
| 93 |
T |
H |
0.0000 |
|
| 94 |
R |
H |
-1.1546 |
|
| 95 |
Q |
H |
-1.4834 |
|
| 96 |
G |
H |
-0.6816 |
|
| 97 |
L |
H |
0.4913 |
|
| 98 |
W |
H |
1.2513 |
|
| 99 |
F |
H |
0.3790 |
|
| 100 |
D |
H |
-1.6379 |
|
| 100A |
S |
H |
-1.9754 |
|
| 100B |
D |
H |
-2.4248 |
|
| 100C |
G |
H |
-2.3172 |
|
| 100D |
R |
H |
-2.8353 |
|
| 100E |
G |
H |
-1.5984 |
|
| 100F |
F |
H |
-0.5340 |
|
| 101 |
D |
H |
-1.6323 |
|
| 102 |
F |
H |
0.0000 |
|
| 103 |
W |
H |
-0.0498 |
|
| 104 |
G |
H |
-0.8956 |
|
| 105 |
Q |
H |
-1.4266 |
|
| 106 |
G |
H |
0.0000 |
|
| 107 |
T |
H |
-0.6786 |
|
| 108 |
T |
H |
-0.4355 |
|
| 109 |
V |
H |
0.0000 |
|
| 110 |
T |
H |
-1.1059 |
|
| 111 |
V |
H |
0.0000 |
|
| 112 |
S |
H |
-1.1834 |
|
| 113 |
S |
H |
-0.9847 |
|
| 114 |
A |
H |
-0.6493 |
|
| 115 |
S |
H |
-0.7945 |
|
| 116 |
T |
H |
-0.9704 |
|
| 117 |
K |
H |
-1.6995 |
|
| 118 |
G |
H |
-1.8057 |
|
| 119 |
P |
H |
-0.8426 |
|
| 120 |
S |
H |
-0.1994 |
|
| 121 |
V |
H |
0.0000 |
|
| 122 |
F |
H |
1.1549 |
|
| 123 |
P |
H |
0.4395 |
|
| 124 |
L |
H |
0.7651 |
|
| 125 |
A |
H |
0.2086 |
|
| 126 |
P |
H |
-0.1646 |
|
| 136 |
A |
H |
0.0147 |
|
| 137 |
A |
H |
0.1730 |
|
| 138 |
L |
H |
0.0000 |
|
| 139 |
G |
H |
0.0000 |
|
| 140 |
C |
H |
0.0000 |
|
| 141 |
L |
H |
0.7663 |
|
| 142 |
V |
H |
0.0000 |
|
| 143 |
K |
H |
-0.5743 |
|
| 144 |
D |
H |
-1.0574 |
|
| 145 |
Y |
H |
0.0000 |
|
| 146 |
F |
H |
0.0000 |
|
| 147 |
P |
H |
0.0000 |
|
| 148 |
E |
H |
-0.4982 |
|
| 149 |
P |
H |
-0.7525 |
|
| 150 |
V |
H |
-0.5963 |
|
| 151 |
T |
H |
-0.5512 |
|
| 152 |
V |
H |
-0.4289 |
|
| 153 |
S |
H |
-0.4283 |
|
| 154 |
W |
H |
0.0000 |
|
| 155 |
N |
H |
-0.9076 |
|
| 156 |
S |
H |
-0.7526 |
|
| 157 |
G |
H |
-0.6147 |
|
| 158 |
A |
H |
-0.2902 |
|
| 159 |
L |
H |
-0.0364 |
|
| 160 |
T |
H |
-0.2958 |
|
| 161 |
S |
H |
-0.3307 |
|
| 162 |
G |
H |
-0.4035 |
|
| 163 |
V |
H |
0.0424 |
|
| 164 |
H |
H |
-0.5631 |
|
| 165 |
T |
H |
0.0814 |
|
| 166 |
F |
H |
0.6724 |
|
| 167 |
P |
H |
0.5311 |
|
| 168 |
A |
H |
1.1094 |
|
| 169 |
V |
H |
2.3176 |
|
| 170 |
L |
H |
1.7569 |
|
| 171 |
Q |
H |
0.5877 |
|
| 172 |
S |
H |
0.0734 |
|
| 173 |
S |
H |
-0.2495 |
|
| 174 |
G |
H |
0.1721 |
|
| 175 |
L |
H |
0.0995 |
|
| 176 |
Y |
H |
0.5606 |
|
| 177 |
S |
H |
0.0000 |
|
| 178 |
L |
H |
0.0000 |
|
| 179 |
S |
H |
0.5611 |
|
| 180 |
S |
H |
0.0000 |
|
| 181 |
V |
H |
0.3475 |
|
| 182 |
V |
H |
0.0000 |
|
| 183 |
T |
H |
-0.0726 |
|
| 184 |
V |
H |
-0.0079 |
|
| 185 |
P |
H |
-0.1142 |
|
| 192 |
Q |
H |
-1.1758 |
|
| 193 |
T |
H |
-0.8953 |
|
| 194 |
Y |
H |
-0.6321 |
|
| 195 |
I |
H |
-1.1238 |
|
| 196 |
C |
H |
0.0000 |
|
| 197 |
N |
H |
-1.6684 |
|
| 198 |
V |
H |
0.0000 |
|
| 199 |
N |
H |
-2.0125 |
|
| 200 |
H |
H |
0.0000 |
|
| 201 |
K |
H |
-3.0015 |
|
| 202 |
P |
H |
-1.8768 |
|
| 203 |
S |
H |
-1.9557 |
|
| 204 |
N |
H |
-2.6136 |
|
| 205 |
T |
H |
-2.3308 |
|
| 206 |
K |
H |
-2.7063 |
|
| 207 |
V |
H |
-1.6941 |
|
| 208 |
D |
H |
-2.7542 |
|
| 209 |
K |
H |
-2.0111 |
|
| 210 |
K |
H |
-2.2453 |
|
| 211 |
V |
H |
0.0000 |
|
| 212 |
P |
H |
-0.6799 |
|