Project name: 5wkz:L

Chain sequence(s)	L: VLTQPPSVSAAPGQKVVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAYVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1821
• Maximal score value: 2.5792
• Average score: -0.6877
• Total score value: -145.7997

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	V	L	1.8241
2	L	L	0.0000
3	T	L	0.2367
4	Q	L	0.0000
5	P	L	-0.4329
6	P	L	-0.6643
7	S	L	-0.5507
8	V	L	-0.1336
9	S	L	-0.0723
10	A	L	0.0000
11	A	L	-0.8175
12	P	L	-1.3438
13	G	L	-1.7517
14	Q	L	-2.3001
15	K	L	-2.4433
16	V	L	0.0000
17	T	L	-0.4815
18	I	L	0.0000
19	S	L	-0.3495
20	C	L	0.0000
21	S	L	-0.2202
22	G	L	0.0137
23	S	L	-0.4940
24	S	L	-0.9665
25	S	L	-0.6428
26	N	L	0.0000
27	I	L	0.0000
28	G	L	-1.1415
29	N	L	-1.2362
30	N	L	-0.1294
31	Y	L	0.7772
32	V	L	0.0000
33	S	L	0.2427
34	W	L	0.0000
35	Y	L	0.1507
36	Q	L	0.0000
37	Q	L	-0.6634
38	L	L	-0.3485
39	P	L	-0.7023
40	G	L	-0.5325
41	T	L	-0.4375
42	A	L	-0.3711
43	P	L	-0.6733
44	K	L	-0.8326
45	L	L	0.0623
46	L	L	0.0000
47	I	L	0.0000
48	Y	L	-0.4967
49	D	L	-0.9142
50	N	L	-1.2238
51	N	L	-2.2602
52	K	L	-2.5978
53	R	L	-2.0756
54	P	L	-0.7148
55	S	L	-0.7549
56	G	L	-0.8693
57	I	L	-0.9358
58	P	L	-1.3483
59	D	L	-2.3722
60	R	L	-1.5768
61	F	L	0.0000
62	S	L	-1.4642
63	G	L	-1.3271
64	S	L	-1.2649
65	K	L	-1.0433
66	S	L	-0.8072
67	G	L	-1.0471
68	T	L	-0.9474
69	S	L	-0.6878
70	A	L	0.0000
71	T	L	-0.5852
72	L	L	0.0000
73	G	L	-0.7998
74	I	L	0.0000
75	T	L	-1.7853
76	G	L	-1.5430
77	L	L	0.0000
78	Q	L	-1.6038
79	T	L	-0.9749
80	G	L	-0.9182
81	D	L	0.0000
82	E	L	-0.8220
83	A	L	0.0000
84	D	L	-0.8824
85	Y	L	0.0000
86	Y	L	0.0422
87	C	L	0.0000
88	G	L	0.0000
89	T	L	0.0000
90	W	L	2.0577
91	D	L	0.0000
92	S	L	0.4370
93	S	L	0.7570
94	L	L	1.4510
95	S	L	0.6637
96	A	L	1.2239
97	Y	L	2.0168
98	V	L	2.5792
99	V	L	0.0000
100	F	L	1.8606
101	G	L	0.0000
102	G	L	-0.1045
103	G	L	-0.4536
104	T	L	0.0000
105	K	L	-0.9778
106	L	L	0.0000
107	T	L	-0.2458
108	V	L	0.0000
109	L	L	-0.0402
110	G	L	-0.6923
111	Q	L	-1.1607
112	P	L	-1.3252
113	K	L	-2.2318
114	A	L	-1.3724
115	A	L	-0.8200
116	P	L	0.0000
117	S	L	-0.4222
118	V	L	0.0000
119	T	L	0.1015
120	L	L	0.0000
121	F	L	1.7498
122	P	L	0.7083
123	P	L	0.0000
124	S	L	-1.0801
125	S	L	-1.8680
126	E	L	-2.8605
127	E	L	-2.4880
128	L	L	-2.4475
129	Q	L	-2.6585
130	A	L	-2.2343
131	N	L	-2.9628
132	K	L	-3.0817
133	A	L	0.0000
134	T	L	-0.1196
135	L	L	0.0000
136	V	L	1.1321
137	C	L	0.0000
138	L	L	0.8689
139	I	L	0.0000
140	S	L	-0.5911
141	D	L	-1.5091
142	F	L	0.0000
143	Y	L	0.0000
144	P	L	-0.9664
145	G	L	-0.9550
146	A	L	-0.2443
147	V	L	-0.2331
148	T	L	-0.2438
149	V	L	0.0000
150	A	L	-0.6225
151	W	L	0.0000
152	K	L	-0.9817
153	A	L	-1.2498
154	D	L	-1.4266
155	S	L	-0.9605
156	S	L	-0.7876
157	P	L	-0.8873
158	V	L	-0.9072
159	K	L	-1.8859
160	A	L	-1.0615
161	G	L	-0.9573
162	V	L	-1.0276
163	E	L	-1.8188
164	T	L	-0.7659
165	T	L	-0.4952
166	T	L	-0.3335
167	P	L	-0.6380
168	S	L	-1.3291
169	K	L	-2.5735
170	Q	L	-2.0518
171	S	L	-1.6849
172	N	L	-2.2591
173	N	L	-2.3384
174	K	L	-2.2770
175	Y	L	-1.4908
176	A	L	-0.7636
177	A	L	0.0000
178	S	L	-0.0191
179	S	L	0.0000
180	Y	L	0.2784
181	L	L	0.0000
182	S	L	-0.6626
183	L	L	-1.1418
184	T	L	-1.8652
185	P	L	-2.5842
186	E	L	-3.1821
187	Q	L	-2.2902
188	W	L	0.0000
189	K	L	-3.0882
190	S	L	-2.3900
191	H	L	-2.4172
192	R	L	-2.5244
193	S	L	-1.5384
194	Y	L	0.0000
195	S	L	-1.0334
196	C	L	0.0000
197	Q	L	-1.1499
198	V	L	0.0000
199	T	L	-0.8078
200	H	L	0.0000
201	E	L	-2.3045
202	G	L	-1.4545
203	S	L	-0.9070
204	T	L	-0.8363
205	V	L	-0.8521
206	E	L	-2.2199
207	K	L	-1.5704
208	T	L	-0.7843
209	V	L	-0.0414
210	A	L	-0.6642
211	P	L	-1.0136
212	T	L	-0.3501