Project name: SOD1

Chain sequence(s)	A: AATTKAVCVLLKGDGPVQGIINFEQKESNGPVKKKVWGSIKGLTEGLHGFHVHEFGDNNTAGCTSAGPHFNPLSRKHGGPKDEEERHVGDLGNVTADKDGVADVSIEEDSVISLSGDHHCCIIIGRTLVVHEEKADDLGKGGNNEESTKTGNAGSRLACGVIGIAQ; F: AATTKAVCVLKGGDDGGPPVVQGIINFEQKESNGPVKKVWGSIKGLTEGLHGFHVHEFGDNNTAGCTSAGPHFNPLSSRKHGGPKDEEERHVGDLGNVTADKDGVADDVSIEEDSVISLSSGGDDHCCIIGRTLVVHEKKADDLGKKGGNNEEESTKTGNAGSRLACGVIGIAQ
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.2547
• Maximal score value: 1.1792
• Average score: -0.3957
• Total score value: -121.0717

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-0.2378
2	T	A	-0.1381
3	K	A	-0.6961
4	A	A	0.0000
5	V	A	0.0000
6	C	A	0.0000
7	V	A	0.3197
8	L	A	0.0000
9	K	A	-1.8788
10	G	A	-0.9050
11	D	A	-1.9245
12	G	A	-0.8441
13	P	A	-0.3419
14	V	A	0.0000
15	Q	A	-1.3935
16	G	A	-0.1567
17	I	A	0.6853
18	I	A	0.0000
19	N	A	-0.2795
20	F	A	0.0000
21	E	A	-0.6467
22	Q	A	0.0000
23	K	A	-2.0240
24	E	A	-2.1777
25	S	A	-0.7903
26	N	A	-1.3226
27	G	A	-0.5034
28	P	A	-0.1450
29	V	A	0.0000
30	K	A	-1.6024
31	V	A	0.0000
32	W	A	0.2553
33	G	A	-0.0496
34	S	A	-0.3129
35	I	A	0.0000
36	K	A	-1.5456
37	G	A	-0.5183
38	L	A	0.0000
39	T	A	-0.4005
40	E	A	-1.8457
41	G	A	-0.1780
42	L	A	1.1792
43	H	A	0.0000
44	G	A	0.0000
45	F	A	0.0000
46	H	A	0.0000
47	V	A	0.0000
48	H	A	0.0000
49	E	A	-0.2364
50	F	A	0.1586
51	G	A	0.0000
52	D	A	-0.3195
53	N	A	-0.3983
54	T	A	-0.0870
55	A	A	0.0247
56	G	A	-0.1594
57	C	A	0.0335
58	T	A	-0.0657
59	S	A	-0.0577
60	A	A	0.0000
61	G	A	-0.1404
62	P	A	-0.2178
63	H	A	0.0000
64	F	A	0.0000
65	N	A	-0.3133
66	P	A	0.0468
67	L	A	1.0815
68	S	A	-0.1111
69	R	A	-0.9038
70	K	A	-1.8017
71	H	A	0.0000
72	G	A	0.0000
73	G	A	0.0000
74	P	A	-0.3586
75	K	A	-1.9070
76	D	A	-1.7352
77	E	A	-2.1004
78	E	A	-0.7524
79	R	A	0.0000
80	H	A	0.0000
81	V	A	0.0000
82	G	A	0.0000
83	D	A	0.0000
84	L	A	0.0000
85	G	A	0.0000
86	N	A	-0.2667
87	V	A	0.0000
88	T	A	0.0909
89	A	A	0.0000
90	D	A	-1.3827
91	K	A	-2.2247
92	D	A	-2.0979
93	G	A	0.0000
94	V	A	0.0016
95	A	A	0.0000
96	D	A	-1.7993
97	V	A	0.0000
98	S	A	-0.1165
99	I	A	-0.0608
100	E	A	-1.9352
101	D	A	0.0000
102	S	A	-0.1161
103	V	A	0.5671
104	I	A	0.0000
105	S	A	0.0000
106	L	A	0.0000
107	S	A	-0.2837
108	G	A	-0.8381
109	D	A	-1.9134
110	H	A	-0.5101
111	C	A	0.0549
112	I	A	0.0000
113	I	A	0.0000
114	G	A	0.0000
115	R	A	-0.2084
116	T	A	0.0000
117	L	A	0.0000
118	V	A	0.0000
119	V	A	0.0000
120	H	A	0.0000
121	E	A	-1.5337
122	K	A	-1.4160
123	A	A	-0.0658
124	D	A	0.0000
125	D	A	-0.3787
126	L	A	0.1729
127	G	A	-0.3649
128	K	A	-1.7842
129	G	A	-0.7633
130	G	A	-0.7050
131	N	A	-1.3822
132	E	A	-2.2547
133	E	A	-1.9058
134	S	A	0.0000
135	T	A	-0.3418
136	K	A	-1.8515
137	T	A	-0.3237
138	G	A	0.0000
139	N	A	-0.2441
140	A	A	0.0000
141	G	A	-0.3473
142	S	A	-0.3633
143	R	A	-0.4558
144	L	A	0.3196
145	A	A	0.0000
146	C	A	0.0000
147	G	A	-0.0088
148	V	A	0.1950
149	I	A	0.0000
150	G	A	0.0000
151	I	A	0.3599
152	A	A	-0.1532
153	Q	A	-1.1972
1	A	F	-0.2255
2	T	F	-0.1632
3	K	F	-0.8091
4	A	F	0.0000
5	V	F	0.0000
6	C	F	0.0000
7	V	F	0.3169
8	L	F	0.0000
9	K	F	-1.8383
10	G	F	-0.7925
11	D	F	-1.9322
12	G	F	-0.8731
13	P	F	-0.5983
14	V	F	0.0000
15	Q	F	-1.1709
16	G	F	-0.1086
17	I	F	0.6952
18	I	F	0.0000
19	N	F	-0.2532
20	F	F	0.0000
21	E	F	-0.6618
22	Q	F	0.0000
23	K	F	-2.0314
24	E	F	-2.1788
25	S	F	-0.7947
26	N	F	-1.3266
27	G	F	-0.3488
28	P	F	-0.2174
29	V	F	0.0000
30	K	F	-1.2335
31	V	F	0.0000
32	W	F	0.2477
33	G	F	-0.0432
34	S	F	-0.3186
35	I	F	0.0000
36	K	F	-1.7552
37	G	F	-0.7833
38	L	F	0.0000
39	T	F	-0.4036
40	E	F	-1.8478
41	G	F	-0.2086
42	L	F	1.0815
43	H	F	0.0000
44	G	F	0.0000
45	F	F	0.0000
46	H	F	0.0000
47	V	F	0.0000
48	H	F	0.0000
49	E	F	-0.2664
50	F	F	0.1559
51	G	F	0.0000
52	D	F	-0.2963
53	N	F	-0.3302
54	T	F	-0.0723
55	A	F	0.0061
56	G	F	-0.2447
57	C	F	0.0275
58	T	F	-0.0629
59	S	F	-0.0557
60	A	F	0.0000
61	G	F	-0.1325
62	P	F	-0.2329
63	H	F	0.0000
64	F	F	0.0000
65	N	F	-0.2847
66	P	F	-0.0155
67	L	F	0.8759
68	S	F	-0.1054
69	R	F	-0.6661
70	K	F	-1.5350
71	H	F	0.0000
72	G	F	0.0000
73	G	F	0.0000
74	P	F	-0.3914
75	K	F	-1.8026
76	D	F	-1.1144
77	E	F	-2.1793
78	E	F	-1.8035
79	R	F	0.0000
80	H	F	0.0000
81	V	F	0.0000
82	G	F	0.0000
83	D	F	0.0000
84	L	F	0.0000
85	G	F	0.0000
86	N	F	-0.2653
87	V	F	0.0000
88	T	F	0.0791
89	A	F	0.0000
90	D	F	-1.4059
91	K	F	-2.2248
92	D	F	-2.0959
93	G	F	0.0000
94	V	F	-0.0020
95	A	F	0.0000
96	D	F	-1.8002
97	V	F	0.0000
98	S	F	-0.1171
99	I	F	-0.0626
100	E	F	-1.8893
101	D	F	0.0000
102	S	F	-0.1568
103	V	F	0.4049
104	I	F	0.0000
105	S	F	-0.0107
106	L	F	0.0000
107	S	F	-0.2001
108	G	F	-0.8228
109	D	F	-1.9268
110	H	F	-0.5819
111	C	F	0.0411
112	I	F	0.0000
113	I	F	0.2054
114	G	F	0.0000
115	R	F	-0.2336
116	T	F	0.0000
117	L	F	0.0000
118	V	F	0.0000
119	V	F	0.0000
120	H	F	0.0000
121	E	F	-1.6867
122	K	F	-1.4491
123	A	F	-0.0787
124	D	F	0.0000
125	D	F	-0.4671
126	L	F	0.1587
127	G	F	-0.3170
128	K	F	-1.7814
129	G	F	-0.7931
130	G	F	-0.6744
131	N	F	-1.1895
132	E	F	-2.1905
133	E	F	-1.5954
134	S	F	0.0000
135	T	F	-0.3238
136	K	F	-1.7068
137	T	F	-0.3316
138	G	F	0.0000
139	N	F	-0.2752
140	A	F	0.0000
141	G	F	-0.3898
142	S	F	-0.3825
143	R	F	-0.5237
144	L	F	0.2745
145	A	F	0.0000
146	C	F	0.0000
147	G	F	0.0000
148	V	F	0.1947
149	I	F	0.0000
150	G	F	0.0000
151	I	F	0.3961
152	A	F	0.0000
153	Q	F	-1.1983