Project name: 4ypg:A
Status: done
submitted: 2019-03-20 20:22:47, status changed: 2019-03-20 20:34:35
Settings
|
Chain sequence(s)
|
A: EIVLTQSPGTLSLSPGERATLSCRASQSVSSTYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.0118
-
Maximal score value
-
1.5406
-
Average score
-
-0.9107
-
Total score value
-
-195.8011
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
A |
-1.8385 |
|
| 2 |
I |
A |
-0.7916 |
|
| 3 |
V |
A |
0.4170 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.6533 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
-0.8658 |
|
| 8 |
P |
A |
-0.4581 |
|
| 9 |
G |
A |
-0.7914 |
|
| 10 |
T |
A |
-0.3061 |
|
| 11 |
L |
A |
-0.0774 |
|
| 12 |
S |
A |
-0.5236 |
|
| 13 |
L |
A |
-0.9938 |
|
| 14 |
S |
A |
-1.6451 |
|
| 15 |
P |
A |
-2.2527 |
|
| 16 |
G |
A |
-2.5633 |
|
| 17 |
E |
A |
-3.0509 |
|
| 18 |
R |
A |
-3.2861 |
|
| 19 |
A |
A |
0.0000 |
|
| 20 |
T |
A |
-0.5435 |
|
| 21 |
L |
A |
0.0000 |
|
| 22 |
S |
A |
-0.8997 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.3620 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-1.0992 |
|
| 27 |
Q |
A |
-1.7759 |
|
| 28 |
S |
A |
-1.4056 |
|
| 29 |
V |
A |
0.0000 |
|
| 30 |
S |
A |
-0.2171 |
|
| 31 |
S |
A |
-0.2138 |
|
| 32 |
T |
A |
0.2711 |
|
| 33 |
Y |
A |
0.6611 |
|
| 34 |
L |
A |
0.0000 |
|
| 35 |
A |
A |
0.0000 |
|
| 36 |
W |
A |
0.0000 |
|
| 37 |
Y |
A |
0.0077 |
|
| 38 |
Q |
A |
-0.8138 |
|
| 39 |
Q |
A |
-1.3772 |
|
| 40 |
K |
A |
-1.8459 |
|
| 41 |
P |
A |
-1.4540 |
|
| 42 |
G |
A |
-1.4077 |
|
| 43 |
Q |
A |
-2.0826 |
|
| 44 |
A |
A |
-1.3226 |
|
| 45 |
P |
A |
-1.3675 |
|
| 46 |
R |
A |
-1.8698 |
|
| 47 |
L |
A |
-0.2778 |
|
| 48 |
L |
A |
0.0000 |
|
| 49 |
I |
A |
0.0000 |
|
| 50 |
Y |
A |
0.8149 |
|
| 51 |
G |
A |
0.3108 |
|
| 52 |
A |
A |
0.0000 |
|
| 53 |
S |
A |
-0.4283 |
|
| 54 |
S |
A |
-0.4230 |
|
| 55 |
R |
A |
-1.1076 |
|
| 56 |
A |
A |
-0.4211 |
|
| 57 |
T |
A |
-0.3646 |
|
| 58 |
G |
A |
-0.6517 |
|
| 59 |
I |
A |
-0.7815 |
|
| 60 |
P |
A |
-1.1910 |
|
| 61 |
D |
A |
-2.3339 |
|
| 62 |
R |
A |
-2.1186 |
|
| 63 |
F |
A |
0.0000 |
|
| 64 |
S |
A |
-0.8889 |
|
| 65 |
G |
A |
-0.4156 |
|
| 66 |
S |
A |
-0.6571 |
|
| 67 |
G |
A |
-1.0620 |
|
| 68 |
S |
A |
-1.0798 |
|
| 69 |
G |
A |
-1.2808 |
|
| 70 |
T |
A |
-1.8278 |
|
| 71 |
D |
A |
-2.2054 |
|
| 72 |
F |
A |
0.0000 |
|
| 73 |
T |
A |
-0.7618 |
|
| 74 |
L |
A |
0.0000 |
|
| 75 |
T |
A |
-0.8305 |
|
| 76 |
I |
A |
0.0000 |
|
| 77 |
S |
A |
-2.4343 |
|
| 78 |
R |
A |
-3.6422 |
|
| 79 |
L |
A |
0.0000 |
|
| 80 |
E |
A |
-2.9358 |
|
| 81 |
P |
A |
-1.9506 |
|
| 82 |
E |
A |
-2.3910 |
|
| 83 |
D |
A |
0.0000 |
|
| 84 |
F |
A |
-0.6215 |
|
| 85 |
A |
A |
0.0000 |
|
| 86 |
V |
A |
-0.0867 |
|
| 87 |
Y |
A |
0.0000 |
|
| 88 |
Y |
A |
0.0829 |
|
| 89 |
C |
A |
0.0000 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
Q |
A |
0.0000 |
|
| 92 |
Y |
A |
-0.0757 |
|
| 93 |
G |
A |
-0.3929 |
|
| 94 |
S |
A |
-0.9223 |
|
| 95 |
S |
A |
-1.1448 |
|
| 96 |
P |
A |
-1.4274 |
|
| 97 |
R |
A |
-1.6720 |
|
| 98 |
T |
A |
-0.4569 |
|
| 99 |
F |
A |
0.7736 |
|
| 100 |
G |
A |
0.0000 |
|
| 101 |
Q |
A |
-0.8179 |
|
| 102 |
G |
A |
-0.5110 |
|
| 103 |
T |
A |
0.0000 |
|
| 104 |
K |
A |
-0.4127 |
|
| 105 |
V |
A |
0.0000 |
|
| 106 |
E |
A |
0.0000 |
|
| 107 |
I |
A |
-0.8351 |
|
| 108 |
K |
A |
-1.2228 |
|
| 109 |
R |
A |
-1.0137 |
|
| 110 |
T |
A |
-0.1800 |
|
| 111 |
V |
A |
0.2041 |
|
| 112 |
A |
A |
-0.1397 |
|
| 113 |
A |
A |
-0.2342 |
|
| 114 |
P |
A |
0.0000 |
|
| 115 |
S |
A |
-0.1541 |
|
| 116 |
V |
A |
0.0000 |
|
| 117 |
F |
A |
1.0309 |
|
| 118 |
I |
A |
1.0757 |
|
| 119 |
F |
A |
1.5406 |
|
| 120 |
P |
A |
0.2802 |
|
| 121 |
P |
A |
-0.5133 |
|
| 122 |
S |
A |
-1.6956 |
|
| 123 |
D |
A |
-3.2671 |
|
| 124 |
E |
A |
-3.4356 |
|
| 125 |
Q |
A |
-2.4279 |
|
| 126 |
L |
A |
-2.4803 |
|
| 127 |
K |
A |
-3.0421 |
|
| 128 |
S |
A |
-1.9801 |
|
| 129 |
G |
A |
-1.4690 |
|
| 130 |
T |
A |
-1.3306 |
|
| 131 |
A |
A |
0.0000 |
|
| 132 |
S |
A |
0.0610 |
|
| 133 |
V |
A |
0.0000 |
|
| 134 |
V |
A |
0.7390 |
|
| 135 |
C |
A |
0.0000 |
|
| 136 |
L |
A |
0.4243 |
|
| 137 |
L |
A |
0.0000 |
|
| 138 |
N |
A |
-0.6511 |
|
| 139 |
N |
A |
-1.4421 |
|
| 140 |
F |
A |
0.0000 |
|
| 141 |
Y |
A |
0.0000 |
|
| 142 |
P |
A |
-1.7412 |
|
| 143 |
R |
A |
-2.8693 |
|
| 144 |
E |
A |
-3.1595 |
|
| 145 |
A |
A |
-2.3408 |
|
| 146 |
K |
A |
-2.4297 |
|
| 147 |
V |
A |
-1.0412 |
|
| 148 |
Q |
A |
-0.6066 |
|
| 149 |
W |
A |
0.0000 |
|
| 150 |
K |
A |
-0.6701 |
|
| 151 |
V |
A |
0.0000 |
|
| 152 |
D |
A |
-1.6654 |
|
| 153 |
N |
A |
-1.5035 |
|
| 154 |
A |
A |
-0.3734 |
|
| 155 |
L |
A |
0.3987 |
|
| 156 |
Q |
A |
-0.3167 |
|
| 157 |
S |
A |
-0.6013 |
|
| 158 |
G |
A |
-1.0069 |
|
| 159 |
N |
A |
-0.9597 |
|
| 160 |
S |
A |
-1.4423 |
|
| 161 |
Q |
A |
-2.3372 |
|
| 162 |
E |
A |
-2.3818 |
|
| 163 |
S |
A |
-1.4138 |
|
| 164 |
V |
A |
-0.8483 |
|
| 165 |
T |
A |
-1.2513 |
|
| 166 |
E |
A |
-2.2335 |
|
| 167 |
Q |
A |
-2.1635 |
|
| 168 |
D |
A |
-2.7608 |
|
| 169 |
S |
A |
-2.1138 |
|
| 170 |
K |
A |
-2.5484 |
|
| 171 |
D |
A |
-2.0763 |
|
| 172 |
S |
A |
-2.0433 |
|
| 173 |
T |
A |
0.0000 |
|
| 174 |
Y |
A |
0.0000 |
|
| 175 |
S |
A |
-1.0776 |
|
| 176 |
L |
A |
0.0000 |
|
| 177 |
S |
A |
-0.6286 |
|
| 178 |
S |
A |
0.0000 |
|
| 179 |
T |
A |
-0.6154 |
|
| 180 |
L |
A |
0.0000 |
|
| 181 |
T |
A |
-0.5134 |
|
| 182 |
L |
A |
-0.8117 |
|
| 183 |
S |
A |
-1.1611 |
|
| 184 |
K |
A |
-2.1816 |
|
| 185 |
A |
A |
-2.0436 |
|
| 186 |
D |
A |
-3.0295 |
|
| 187 |
Y |
A |
0.0000 |
|
| 188 |
E |
A |
-4.0118 |
|
| 189 |
K |
A |
-3.7844 |
|
| 190 |
H |
A |
-3.3660 |
|
| 191 |
K |
A |
-3.4810 |
|
| 192 |
V |
A |
-1.6502 |
|
| 193 |
Y |
A |
0.0000 |
|
| 194 |
A |
A |
0.0000 |
|
| 195 |
C |
A |
0.0000 |
|
| 196 |
E |
A |
-0.8313 |
|
| 197 |
V |
A |
0.0000 |
|
| 198 |
T |
A |
-1.1287 |
|
| 199 |
H |
A |
0.0000 |
|
| 200 |
Q |
A |
-1.7968 |
|
| 201 |
G |
A |
-0.4448 |
|
| 202 |
L |
A |
-0.1615 |
|
| 203 |
S |
A |
-0.3841 |
|
| 204 |
S |
A |
-0.3564 |
|
| 205 |
P |
A |
-0.5464 |
|
| 206 |
V |
A |
0.1031 |
|
| 207 |
T |
A |
-0.3652 |
|
| 208 |
K |
A |
-0.5004 |
|
| 209 |
S |
A |
-0.3294 |
|
| 210 |
F |
A |
0.0000 |
|
| 211 |
N |
A |
-2.0627 |
|
| 212 |
R |
A |
-2.8440 |
|
| 213 |
G |
A |
-2.1879 |
|
| 214 |
E |
A |
-2.3813 |
|
| 215 |
C |
A |
-0.7469 |
|