Project name: 4b44e695caf57b2
Status: done
submitted: 2018-11-16 23:42:20, status changed: 2018-11-16 23:49:26
Settings
|
Chain sequence(s)
|
A: GGGGGGGAQRRRPPPPQSALEKVAAQEGLSLQQLAGKWFLVSMASRCSYLAEHSHQLEATTMTVTVLDGQSLAISTFRKLDRMCWEIRQHYLPAQAPGRFLLKGHRKSSKVDVVVGEADASSFVILYYQKGRSISVKLYGRSSLVSDAVMDKFEQRVRAVGLSEDVTYRFPTYGFCDSADEFHILDVMCLPTC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8361
-
Maximal score value
-
1.6657
-
Average score
-
-0.8338
-
Total score value
-
-160.9164
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
G |
A |
-0.8845 |
|
| 2 |
G |
A |
-1.3586 |
|
| 3 |
G |
A |
-1.1313 |
|
| 4 |
G |
A |
-1.4244 |
|
| 5 |
G |
A |
-1.4390 |
|
| 6 |
G |
A |
-1.1897 |
|
| 7 |
G |
A |
-1.0139 |
|
| 8 |
A |
A |
-1.1899 |
|
| 9 |
Q |
A |
-2.1485 |
|
| 10 |
R |
A |
-3.3980 |
|
| 11 |
R |
A |
-3.8361 |
|
| 12 |
R |
A |
-3.5968 |
|
| 13 |
P |
A |
-2.0984 |
|
| 14 |
P |
A |
-1.9605 |
|
| 15 |
P |
A |
-1.3119 |
|
| 16 |
P |
A |
-1.1704 |
|
| 17 |
Q |
A |
-1.8610 |
|
| 18 |
S |
A |
-1.9937 |
|
| 19 |
A |
A |
-1.7172 |
|
| 20 |
L |
A |
0.0000 |
|
| 21 |
E |
A |
-2.6738 |
|
| 22 |
K |
A |
-2.4858 |
|
| 23 |
V |
A |
-1.2588 |
|
| 24 |
A |
A |
-1.1315 |
|
| 25 |
A |
A |
-1.2778 |
|
| 26 |
Q |
A |
-1.6461 |
|
| 27 |
E |
A |
-2.3002 |
|
| 28 |
G |
A |
-1.5188 |
|
| 29 |
L |
A |
0.0000 |
|
| 30 |
S |
A |
-1.3995 |
|
| 31 |
L |
A |
0.0000 |
|
| 32 |
Q |
A |
-1.7348 |
|
| 33 |
Q |
A |
-1.9826 |
|
| 34 |
L |
A |
0.0000 |
|
| 35 |
A |
A |
-0.8109 |
|
| 36 |
G |
A |
-0.8140 |
|
| 37 |
K |
A |
-0.8624 |
|
| 38 |
W |
A |
0.0000 |
|
| 39 |
F |
A |
0.2008 |
|
| 40 |
L |
A |
0.0000 |
|
| 41 |
V |
A |
0.0000 |
|
| 42 |
S |
A |
0.0000 |
|
| 43 |
M |
A |
-0.2826 |
|
| 44 |
A |
A |
0.0000 |
|
| 45 |
S |
A |
0.0000 |
|
| 46 |
R |
A |
-1.8706 |
|
| 47 |
C |
A |
-1.5000 |
|
| 48 |
S |
A |
0.0000 |
|
| 49 |
Y |
A |
-1.1149 |
|
| 50 |
L |
A |
-0.5847 |
|
| 51 |
A |
A |
-1.0715 |
|
| 52 |
E |
A |
-1.5427 |
|
| 53 |
H |
A |
-1.6390 |
|
| 54 |
S |
A |
-1.6443 |
|
| 55 |
H |
A |
-2.0875 |
|
| 56 |
Q |
A |
-1.8634 |
|
| 57 |
L |
A |
-1.0658 |
|
| 58 |
E |
A |
-0.7611 |
|
| 59 |
A |
A |
0.0000 |
|
| 60 |
T |
A |
0.0000 |
|
| 61 |
T |
A |
0.0000 |
|
| 62 |
M |
A |
0.0000 |
|
| 63 |
T |
A |
-0.4629 |
|
| 64 |
V |
A |
0.0000 |
|
| 65 |
T |
A |
-0.3085 |
|
| 66 |
V |
A |
-0.2641 |
|
| 67 |
L |
A |
-0.4212 |
|
| 68 |
D |
A |
-1.7853 |
|
| 69 |
G |
A |
-1.4171 |
|
| 70 |
Q |
A |
-1.3050 |
|
| 71 |
S |
A |
0.0000 |
|
| 72 |
L |
A |
0.0000 |
|
| 73 |
A |
A |
-0.0563 |
|
| 74 |
I |
A |
0.0000 |
|
| 75 |
S |
A |
-0.3069 |
|
| 76 |
T |
A |
-0.2195 |
|
| 77 |
F |
A |
0.0000 |
|
| 78 |
R |
A |
-0.7232 |
|
| 79 |
K |
A |
-1.0032 |
|
| 80 |
L |
A |
-0.9813 |
|
| 81 |
D |
A |
-2.1772 |
|
| 82 |
R |
A |
-2.3032 |
|
| 83 |
M |
A |
-1.0004 |
|
| 84 |
C |
A |
-0.8092 |
|
| 85 |
W |
A |
-0.2724 |
|
| 86 |
E |
A |
0.0000 |
|
| 87 |
I |
A |
0.1426 |
|
| 88 |
R |
A |
-0.4620 |
|
| 89 |
Q |
A |
-0.1413 |
|
| 90 |
H |
A |
0.1810 |
|
| 91 |
Y |
A |
0.3657 |
|
| 92 |
L |
A |
0.1054 |
|
| 93 |
P |
A |
-0.6410 |
|
| 94 |
A |
A |
-0.7252 |
|
| 95 |
Q |
A |
-1.2698 |
|
| 96 |
A |
A |
-0.9512 |
|
| 97 |
P |
A |
-1.1213 |
|
| 98 |
G |
A |
0.0000 |
|
| 99 |
R |
A |
-0.8179 |
|
| 100 |
F |
A |
0.0000 |
|
| 101 |
L |
A |
-0.3355 |
|
| 102 |
L |
A |
-0.2877 |
|
| 103 |
K |
A |
-1.0768 |
|
| 104 |
G |
A |
-2.3427 |
|
| 105 |
H |
A |
-2.7272 |
|
| 106 |
R |
A |
-3.4564 |
|
| 107 |
K |
A |
-3.1609 |
|
| 108 |
S |
A |
-2.4344 |
|
| 109 |
S |
A |
-2.2288 |
|
| 110 |
K |
A |
-2.6727 |
|
| 111 |
V |
A |
-1.2125 |
|
| 112 |
D |
A |
-1.0820 |
|
| 113 |
V |
A |
0.0000 |
|
| 114 |
V |
A |
0.0000 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
G |
A |
0.0000 |
|
| 117 |
E |
A |
-0.9832 |
|
| 118 |
A |
A |
-1.1046 |
|
| 119 |
D |
A |
-1.4802 |
|
| 120 |
A |
A |
-1.3113 |
|
| 121 |
S |
A |
-0.9478 |
|
| 122 |
S |
A |
-0.4887 |
|
| 123 |
F |
A |
-0.2638 |
|
| 124 |
V |
A |
0.0000 |
|
| 125 |
I |
A |
0.0000 |
|
| 126 |
L |
A |
0.0000 |
|
| 127 |
Y |
A |
0.0000 |
|
| 128 |
Y |
A |
-0.1208 |
|
| 129 |
Q |
A |
-1.3282 |
|
| 130 |
K |
A |
-1.6381 |
|
| 131 |
G |
A |
-1.9148 |
|
| 132 |
R |
A |
-2.2216 |
|
| 133 |
S |
A |
0.0000 |
|
| 134 |
I |
A |
0.0000 |
|
| 135 |
S |
A |
0.0000 |
|
| 136 |
V |
A |
0.0000 |
|
| 137 |
K |
A |
-0.2541 |
|
| 138 |
L |
A |
0.0000 |
|
| 139 |
Y |
A |
0.0000 |
|
| 140 |
G |
A |
0.0000 |
|
| 141 |
R |
A |
-0.6433 |
|
| 142 |
S |
A |
-0.1089 |
|
| 143 |
S |
A |
0.5974 |
|
| 144 |
L |
A |
1.1889 |
|
| 145 |
V |
A |
0.5956 |
|
| 146 |
S |
A |
-0.5989 |
|
| 147 |
D |
A |
-1.9322 |
|
| 148 |
A |
A |
-1.4509 |
|
| 149 |
V |
A |
-1.0788 |
|
| 150 |
M |
A |
-1.4661 |
|
| 151 |
D |
A |
-2.7399 |
|
| 152 |
K |
A |
-2.1022 |
|
| 153 |
F |
A |
0.0000 |
|
| 154 |
E |
A |
-1.9010 |
|
| 155 |
Q |
A |
-2.0208 |
|
| 156 |
R |
A |
-1.3896 |
|
| 157 |
V |
A |
0.0000 |
|
| 158 |
R |
A |
-1.6150 |
|
| 159 |
A |
A |
-0.7314 |
|
| 160 |
V |
A |
-0.5136 |
|
| 161 |
G |
A |
-0.8160 |
|
| 162 |
L |
A |
0.0000 |
|
| 163 |
S |
A |
-1.7419 |
|
| 164 |
E |
A |
-2.3337 |
|
| 165 |
D |
A |
-2.5119 |
|
| 166 |
V |
A |
-1.7161 |
|
| 167 |
T |
A |
0.0000 |
|
| 168 |
Y |
A |
0.0000 |
|
| 169 |
R |
A |
-1.1090 |
|
| 170 |
F |
A |
-0.4244 |
|
| 171 |
P |
A |
-0.1209 |
|
| 172 |
T |
A |
0.6467 |
|
| 173 |
Y |
A |
1.2527 |
|
| 174 |
G |
A |
0.0499 |
|
| 175 |
F |
A |
0.1718 |
|
| 176 |
C |
A |
0.0000 |
|
| 177 |
D |
A |
-1.8770 |
|
| 178 |
S |
A |
-1.5506 |
|
| 179 |
A |
A |
-1.2424 |
|
| 180 |
D |
A |
-1.9479 |
|
| 181 |
E |
A |
-1.5758 |
|
| 182 |
F |
A |
0.6669 |
|
| 183 |
H |
A |
0.2063 |
|
| 184 |
I |
A |
0.0716 |
|
| 185 |
L |
A |
0.3206 |
|
| 186 |
D |
A |
-0.9973 |
|
| 187 |
V |
A |
0.0871 |
|
| 188 |
M |
A |
0.4171 |
|
| 189 |
C |
A |
0.5466 |
|
| 190 |
L |
A |
1.6657 |
|
| 191 |
P |
A |
0.9745 |
|
| 192 |
T |
A |
0.6469 |
|
| 193 |
C |
A |
0.9096 |
|