Project name: 3mlv

Chain sequence(s)	A: YLLTQPPSVSVSPGQTASISCSGDKLDDKYVSWYYQRPGQSPVLLMYQDFKRPSGIPERLSGSKSGKTATLTISGTQSLDEGDYYCQAWDASTGVSGGGTKLTVLFGEGTRLTVLAQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPTEVQLVESGGEVKQPGQSLKISCKSSGYNFLDSWIGWVRQIPGKGLEWIGIIYPDDSDAHYSPSFEGQVTMSVDKSISTAYLQWTTLQASDTGKYFCTRLYLFEGAQSSNAFDLWGQGTMILVSSGTTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.2077
• Maximal score value: 1.6203
• Average score: -0.7397
• Total score value: -326.9431

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	Y	A	0.4968
3	L	A	1.2668
4	L	A	0.0000
5	T	A	-0.4318
6	Q	A	0.0000
7	P	A	-0.8332
8	P	A	-1.1993
9	S	A	-0.9633
11	V	A	-0.4078
12	S	A	-0.0794
13	V	A	-0.2116
14	S	A	-0.4293
15	P	A	-0.9722
16	G	A	-1.5359
17	Q	A	-1.7417
18	T	A	-1.0672
19	A	A	0.0000
20	S	A	-0.2645
21	I	A	0.0000
22	S	A	-0.2491
23	C	A	0.0000
24	S	A	-1.0138
25	G	A	-1.4189
26	D	A	-2.9341
27	K	A	-3.2712
28	L	A	0.0000
29	D	A	-4.2077
30	D	A	-3.6828
31	K	A	-2.4789
32	Y	A	-0.7260
33	V	A	0.0000
34	S	A	0.0000
35	W	A	0.0000
36	Y	A	0.0000
37	Y	A	0.0000
38	Q	A	-1.3981
39	R	A	-2.1001
40	P	A	-1.6567
41	G	A	-1.6816
42	Q	A	-2.0908
43	S	A	-1.2781
44	P	A	0.0000
45	V	A	0.5118
46	L	A	0.0000
47	L	A	0.0000
48	M	A	0.0000
49	Y	A	0.1032
50	Q	A	0.0000
51	D	A	0.2080
52	F	A	0.9847
53	K	A	-0.0464
54	R	A	-1.0250
55	P	A	-0.5027
56	S	A	-0.5251
57	G	A	-0.7336
58	I	A	-0.7587
59	P	A	-1.5045
60	E	A	-2.5847
61	R	A	-2.1747
62	L	A	0.0000
63	S	A	-0.7842
64	G	A	0.0595
65	S	A	-0.1330
66	K	A	-1.0045
67	S	A	-1.3280
68	G	A	-2.7694
69	K	A	-3.7352
70	T	A	-1.8341
71	A	A	0.0000
72	T	A	-0.2395
73	L	A	0.0000
74	T	A	-0.4971
75	I	A	0.0000
76	S	A	-1.5409
77	G	A	-1.4968
78	T	A	0.0000
79	Q	A	-1.7309
80	S	A	-0.9145
81	L	A	0.0000
82	D	A	-1.4702
83	E	A	-1.7478
84	G	A	0.0000
85	D	A	-2.0992
86	Y	A	0.0000
87	Y	A	0.0000
88	C	A	0.0000
89	Q	A	0.0000
90	A	A	0.0000
91	W	A	0.0000
92	D	A	-0.5298
93	A	A	-0.7082
94	S	A	-1.0217
95	T	A	-0.8931
95A	G	A	-0.4141
95B	V	A	1.0713
95C	S	A	0.1039
95D	G	A	-0.7922
95E	G	A	-1.0594
95F	G	A	-1.3573
96	T	A	-1.3985
97	K	A	-1.8238
98	L	A	-0.6733
99	T	A	-0.0279
100	V	A	0.0000
101	L	A	1.6203
102	F	A	0.5485
103	G	A	0.0000
104	E	A	-2.0593
105	G	A	-1.8817
106	T	A	0.0000
106A	R	A	-2.3538
107	L	A	0.0000
108	T	A	-0.6151
109	V	A	0.0000
110	L	A	0.8461
111	A	A	-0.0173
112	Q	A	-0.7580
113	P	A	-1.1294
114	K	A	-2.1905
115	A	A	-1.2992
116	A	A	-0.7503
117	P	A	-0.6143
118	S	A	-0.3821
119	V	A	0.0000
120	T	A	-0.3404
121	L	A	-0.2079
122	F	A	0.0000
123	P	A	-0.0494
124	P	A	0.0000
125	S	A	0.0000
126	S	A	-0.8245
127	E	A	-1.4427
128	E	A	0.0000
129	L	A	-1.6865
130	Q	A	-2.0348
131	A	A	-1.7864
132	N	A	-2.7032
133	K	A	-2.8597
134	A	A	0.0000
135	T	A	0.0000
136	L	A	0.0000
137	V	A	0.0000
138	C	A	0.0000
139	L	A	0.0000
140	I	A	0.0000
141	S	A	-0.8134
142	D	A	-1.3082
143	F	A	0.0000
144	Y	A	-1.2782
145	P	A	-0.9814
146	G	A	-0.6687
147	A	A	-0.2115
148	V	A	-0.1519
149	T	A	-0.2083
150	V	A	0.0000
151	A	A	-0.5340
152	W	A	0.0000
153	K	A	-0.8275
154	A	A	0.0000
155	D	A	-1.4464
156	S	A	-0.8635
157	S	A	-0.4461
158	P	A	0.0000
159	V	A	-0.6612
160	K	A	-1.8069
161	A	A	-1.0239
162	G	A	-1.1379
163	V	A	-1.1795
164	E	A	-1.6264
165	T	A	-0.5741
166	T	A	-0.2850
167	T	A	-0.1176
168	P	A	-0.4199
169	S	A	-0.9488
170	K	A	-2.0000
171	Q	A	-1.6921
172	S	A	-1.3595
173	N	A	-1.9731
174	N	A	-1.8776
175	K	A	-1.9248
176	Y	A	-1.2255
177	A	A	0.0000
178	A	A	0.0000
179	S	A	0.0000
180	S	A	0.0000
181	Y	A	0.0000
182	L	A	0.0000
183	S	A	-0.8354
184	L	A	-1.0451
185	T	A	-1.9672
186	P	A	-2.5203
187	E	A	-3.1545
188	Q	A	-2.6307
189	W	A	0.0000
190	K	A	-3.1142
191	S	A	0.0000
192	H	A	-2.4831
193	K	A	-2.5856
194	S	A	-1.4882
195	Y	A	0.0000
196	S	A	0.0000
197	C	A	0.0000
198	Q	A	-0.9819
199	V	A	0.0000
200	T	A	-0.6613
201	H	A	0.0000
202	E	A	-2.3021
203	G	A	-1.4386
204	S	A	-0.8741
205	T	A	-0.6321
206	V	A	-0.4510
207	E	A	-1.7779
208	K	A	-1.7032
209	T	A	-0.9588
210	V	A	-0.3800
211	A	A	-0.8334
212	P	A	-0.9280
1	E	A	-1.5672
2	V	A	-0.3043
3	Q	A	-0.7007
4	L	A	0.0000
5	V	A	-0.1135
6	E	A	-0.5919
7	S	A	-0.8175
8	G	A	-1.0609
9	G	A	-1.2794
10	E	A	-1.5998
11	V	A	-0.7937
12	K	A	-1.4944
13	Q	A	-1.8565
14	P	A	-1.7201
15	G	A	-1.6136
16	Q	A	-1.8573
17	S	A	-1.5164
18	L	A	0.0000
19	K	A	-2.0386
20	I	A	0.0000
21	S	A	-0.6539
22	C	A	0.0000
23	K	A	-0.9452
24	S	A	-0.4674
25	S	A	-0.7053
26	G	A	-0.9757
27	Y	A	-0.9024
28	N	A	-1.3758
29	F	A	0.0000
30	L	A	-0.8622
31	D	A	-1.3943
32	S	A	0.0000
33	W	A	0.1627
34	I	A	0.0000
35	G	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	0.0000
39	Q	A	0.0000
40	I	A	-0.7940
41	P	A	-1.0124
42	G	A	-1.3278
43	K	A	-2.3221
44	G	A	-1.6896
45	L	A	0.0000
46	E	A	-0.7437
47	W	A	0.0000
48	I	A	0.0000
49	G	A	0.0000
50	I	A	0.0000
51	I	A	0.0000
52	Y	A	-0.9362
53	P	A	0.0000
54	D	A	-2.0880
55	D	A	-2.5659
56	S	A	-2.0668
57	D	A	-2.4822
58	A	A	-1.1892
59	H	A	-0.9042
60	Y	A	-0.9025
61	S	A	-0.7415
62	P	A	-1.2188
63	S	A	-0.9949
64	F	A	0.0000
65	E	A	-2.3675
66	G	A	-1.7762
67	Q	A	-1.7074
68	V	A	0.0000
69	T	A	-0.9929
70	M	A	0.0000
71	S	A	-0.3666
72	V	A	-0.6475
73	D	A	-1.0764
74	K	A	-1.5308
75	S	A	-0.2415
76	I	A	0.9380
77	S	A	-0.3324
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.5428
81	L	A	0.0000
82	Q	A	-1.5987
83	W	A	0.0000
84	T	A	-0.9462
85	T	A	-1.2148
86	L	A	0.0000
87	Q	A	-1.7950
88	A	A	-0.9689
89	S	A	-0.5383
90	D	A	0.0000
91	T	A	-0.3218
92	G	A	0.0000
93	K	A	-0.8289
94	Y	A	0.0000
95	F	A	0.0000
96	C	A	0.0000
97	T	A	0.0000
98	R	A	0.0000
99	L	A	0.0000
100	Y	A	0.8270
101	L	A	0.9096
102	F	A	-0.3296
103	E	A	-1.9748
104	G	A	-1.7767
105	A	A	-1.1678
106	Q	A	-1.8591
107	S	A	-1.4109
108	S	A	0.0000
109	N	A	-0.0058
110	A	A	0.0000
111	F	A	0.0000
112	D	A	0.0610
113	L	A	0.2015
114	W	A	-0.0626
115	G	A	0.0000
116	Q	A	-1.5099
117	G	A	-1.0678
118	T	A	0.0000
119	M	A	-0.4897
120	I	A	0.0000
121	L	A	-0.3974
122	V	A	0.0000
123	S	A	-0.9787
124	S	A	-0.7850
125	G	A	-0.9789
126	T	A	-0.5841
127	T	A	-0.7934
128	K	A	-1.1741
129	G	A	-1.1565
130	P	A	-0.6482
131	S	A	-0.5630
132	V	A	0.0000
133	F	A	0.0000
134	P	A	-0.9377
135	L	A	0.0000
136	A	A	0.0000
137	P	A	-0.7895
138	S	A	-1.3121
139	S	A	-1.7964
140	K	A	-2.2242
141	S	A	-1.4557
142	T	A	-1.1128
143	S	A	-0.9650
144	G	A	-0.9727
145	G	A	-0.8789
146	T	A	-0.5580
147	A	A	-0.3004
148	A	A	-0.1950
149	L	A	0.0000
150	G	A	0.0000
151	C	A	0.0000
152	L	A	0.0000
153	V	A	0.0000
154	K	A	0.0000
155	D	A	-0.6855
156	Y	A	0.0000
157	F	A	0.0000
158	P	A	0.0000
159	E	A	-1.8074
160	P	A	-1.4506
161	V	A	-1.1693
162	T	A	-0.8309
163	V	A	-0.1383
164	S	A	-0.3405
165	W	A	0.0000
166	N	A	-0.7879
167	S	A	-0.7140
168	G	A	-0.5526
169	A	A	-0.2667
170	L	A	-0.0360
171	T	A	-0.1760
172	S	A	-0.2656
173	G	A	-0.3249
174	V	A	0.2282
175	H	A	-0.1097
176	T	A	0.0698
177	F	A	0.0000
178	P	A	-0.1965
179	A	A	-0.0981
180	V	A	0.0000
181	L	A	0.4593
182	Q	A	-0.3699
183	S	A	-0.4648
184	S	A	-0.3668
185	G	A	-0.2348
186	L	A	-0.3057
187	Y	A	-0.0615
188	S	A	0.0000
189	L	A	0.2792
190	S	A	0.0000
191	S	A	0.0000
192	V	A	0.1841
193	V	A	0.0000
194	T	A	-0.1344
195	V	A	0.0000
196	P	A	-0.7075
197	S	A	-0.7725
198	S	A	-0.7923
199	S	A	-0.5972
200	L	A	-0.8672
201	G	A	-1.0433
202	T	A	-0.7136
203	Q	A	-1.1987
204	T	A	-1.0710
205	Y	A	0.0000
206	I	A	-1.2580
207	C	A	0.0000
208	N	A	-1.4487
209	V	A	0.0000
210	N	A	-1.8499
211	H	A	0.0000
212	K	A	-2.9119
213	P	A	-2.0918
214	S	A	-1.8408
215	N	A	-2.5408
216	T	A	-2.0045
217	K	A	-2.4714
218	V	A	-1.3636
219	D	A	-2.3905
220	K	A	-1.8439
221	K	A	-2.5353
222	V	A	0.0000
223	E	A	-2.6888
224	P	A	-1.9215
225	K	A	-2.5653